A 1.8 kb alternative transcript from the human epidermal growth factor receptor gene encodes a truncated form of the receptor

Nucleic Acids Research

Volumn 24, Issue 20, 1996, Pages 4050-4056

  Reiter, Jill L ^a   Maihle, Nita J ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; GAMMA UROGASTRONE; MEMBRANE PROTEIN; MONOCLONAL ANTIBODY; PROTEIN TYROSINE KINASE;

AMINO ACID SEQUENCE; ARTICLE; CELL DIFFERENTIATION; CELL GROWTH; CONTROLLED STUDY; DNA SEQUENCE; DNA TRANSCRIPTION; DNA TRANSFECTION; ENZYME ACTIVE SITE; EXON; FIBROBLAST; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; INTRON; LIGAND BINDING; MOLECULAR CLONING; ONCOGENE C ERB; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTO ONCOGENE; STOP CODON;

ALTERNATIVE SPLICING; BASE SEQUENCE; CELLS, CULTURED; CLONING, MOLECULAR; DNA PROBES; GENE EXPRESSION REGULATION; HUMANS; MOLECULAR SEQUENCE DATA; ONCOGENES; POLYMERASE CHAIN REACTION; PRECIPITIN TESTS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS; SEQUENCE DELETION; TRANSCRIPTION, GENETIC;

EID: 0029834942     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/24.20.4050     Document Type: Article

References (43)

1. Downward, J., Yarden, Y., Mayes, E., Scrace, G., Totty, N., Stockwell, P., Ullrich, A., Schlessinger, J. and Waterfield, M. D. (1984) Nature, 307, 521-527.
2. Ullrich, A., Coussens, L., Hayflick, J. S., Dull, T. J., Gray, A., Tam, A. W., Lee, J., Yarden, Y, Libermann, T. A., Schlessinger, J., Downward, J., Mayes, E. L. V., Whittle, N., Waterfield, M. D. and Seeburg, P. H. (1984) Nature, 309, 418-425.
3. Coussens, L., Yang-Feng, T. L., Liao, Y.-C., Chen, E., Gray, A., McGrath, J., Seeburg, P. H., Libermann, T. A., Schlessinger, J., Francke, U., Levinson, A. and Ullrich, A. (1985) Science, 230, 1132-1139.
4. Kraus, M. H., Issing, W., Miki, T., Popescu, N. C. and Aaronson, S. A. (1989) Proc. Natl Acad. Sci. USA, 86, 9193-9197.
5. Plowman, G. D., Whitney, G. S., Neubauer, M. G., Green, J. M., McDonald, V. L., Todaro, G. J. and Shoyab, M. (1990) Proc. Natl Acad. Sci. USA, 87, 4905-4909.
6. Plowman, G. D., Culouscou, J.-M., Whitney, G. S., Green, J. M., Carlton, G. W., Foy, L., Neubauer, M. G. and Shoyab, M. (1993) Proc. Natl Acad. Sci. USA, 90, 1746-1750.
7. Lax, I., Johnson, A., Howk, R., Sap, J., Bellot, F., Winkler, M., Ullrich, A., Vennstrom, B., Schlessinger, J. and Givol, D. (1988) Mol. Cell. Biol., 8, 1970-1978.
8. Lax, I., Fischer, R., Ng, C., Segre, J., Ullrich, A., Givol, D. and Schlessinger, J. (1991) Cell Regul., 2, 337-345.
9. Maihle, N. J., Flickinger, T. W., Raines, M. A., Sanders, M. L. and Kung, H.-J. (1991) Proc. Natl Acad. Sci. USA, 88, 1825-1829.
10. Fetch, L. A., Harris, J., Raymond, V. W., Blasband, A., Lee, D. C. and Earp, H. S. (1990) Mol. Cell. Biol., 10, 2973-2982.
11. Merlino, G. T., Ishii, S., Whang-Peng, J., Knutsen, T., Xu, Y.-h., Clark, A. J. L., Stratton, R. H., Wilson, R. K., Ma, D. P., Roe, B. A., Hunts, J. H., Shimizu, N. and Pastan, I. (1985) Mol. Cell. Biol., 5, 1722-1734.
12. Hunts, J. H., Shimizu, N., Yamamoto, T., Toyoshima, K., Merlino, G. T., Xu, Y.-h. and Pastan, I. (1985) Somat. Cell Mol. Genet., 11, 477-484.
13. Scott, G. K., Robles, R., Park, J. W., Montgomery, P. A., Daniel, J., Holmes, W. E., Lee, J., Keller, G. A., Li, W.-L., Fendly, B. M., Wood, W. I., Shepard, H. M. and Benz, C. C. (1993) Mol. Cell. Biol., 13, 2247-2257.
14. Katoh, M., Yazaki, Y., Sugimura, T. and Terada, M. (1993) Biochem. Biophys. Res. Commun., 192, 1189-1197.
15. Heaney, M. L. and Golde, D. W. (1993) Blood, 82, 1945-1948.
16. Flickinger, T. W., Maihle, N. J. and Kung, H.-J. (1992) Mol. Cell. Biol., 12, 883-893.
17. Prywes, R., Livneh, E., Ullrich, A. and Schlessinger, J. (1986) EMBO J., 5, 2179-2190.
18. Chen, W. S., Lazar, C. S., Poenie, M., Tsien, R. Y., Gill, G. N. and Rosenfeld, M. G. (1987) Nature, 328, 820-823.
19. Murphy, A. J. M., Kung, A. L., Swirski, R. A. and Schimke, R. T. (1992) Methods, 4, 111-131.
20. Chomczynski, P. and Sacchi, N. (1987) Anal. Biochem., 162, 156-159.
21. Moscovici, C., Moscovici, M. G., Jiminez, H., Lai, M. M. C., Hayman, M. J. and Vogt, P. K. (1977) Cell, 11, 95-103.
22. Ausubel, F. M., Brent, R., Kingston, R. E., Moore, D. D., Seidman, J. G., Smith, J. A. and Struhl, K. (1994) Current Protocols in Molecular Biology, John Wiley & Sons, Inc., New York.
23. Maihle, N. J., Raines, M. A., Flickinger, T. W. and Kung, H.-J. (1988) Mol. Cell. Biol., 8, 4868-4876.
24. Ilekis, J. V., Stark, B. C. and Scoccia, B. (1995) Mol. Reprod. Dev., 41, 149-156.
25. Chen, E. Y., Liao, Y.-C., Smith, D. H., Barrera-Saldaña, H. A., Gelinas, R. E. and Seeburg, P. H. (1989) Genomics, 4, 479-497.
26. Johnson, A. C., Ishii, S., Jinno, Y., Pastan, I. and Merlino, G. T. (1988) J. Biol. Chem., 263, 5693-5699.
27. Ishii, S., Xu, Y.-h., Stratton, R. H., Roe, B. A., Merlino, G. T. and Pastan, I. (1985) Proc. Natl Acad. Sci. USA, 82, 4920-4924.
28. Haley, J., Whittle, N., Bennett, P., Kinchington, D., Ullrich, A. and Waterfield, M. (1987) Oncogene Res., 1, 375-396.
29. Reiter, J. L. and Maihle, N. J. (unpublished) cDNA 161, U48722; intron 10, U48723; exon 4/intron 4, U48724; intron 5/exon 6, U48725; exon 8/intron 8/exon 9, U48726; intron 11/exon 12, U48727; intron 12/exon 13/intron 13, U48728; and exon 15/intron 15, U48729.
30. Callaghan, T., Antczak, M., Flickinger, T., Raines, M., Myers, M. and Kung, H.-J. (1993) Oncogene, 8, 2939-2948.
31. Waterfield, M. D., Mayes, E. L. V., Stroobant, P., Bennet, P. L. P., Young, S., Goodfellow, P. N., Banting, G. S. and Ozanne, B. (1982) J. Cell. Biochem., 20, 149-161.
32. Wu, D., Wang, L., Sato, G. H., West, K. A., Harris, W. R., Crabb, J. W. and Sato, J. D. (1989) J. Biol. Chem., 264, 17469-17475.
33. Kawamoto, T., Sato, J. D., Le, A., Polikoff, J., Sato, G. H. and Mendelsohn, J. (1983) Proc. Natl Acad. Sci. USA, 80, 1337-1341.
34. Sato, J. D., Kawamoto, T., Le, A. D., Mendelsohn, J., Polikoff, J. and Sato, G. H. (1983) Mol. Biol. Med., 1, 511-529.
35. Massagué, J. (1983) J. Biol. Chem., 258, 13614-13620.
36. Winkler, M. E., O'Connor, L., Winget, M. and Fendly, B. (1989) Biochemistry, 28, 6373-6378.
37. Harte, M. T. and Gentry, L. E. (1995) Arch. Biochem. Biophys., 322, 378-389.
38. Basu, A., Raghunath, M., Bishayee, S. and Das, M. (1989) Mol. Cell. Biol., 9, 671-677.
39. Nieto-Sampedro, M. (1988) Science, 240, 1784-1786.
40. Nieto-Sampedro, M. and Broderick, J. T. (1989) J. Neurosci. Res., 22, 28-35.
41. Junier, M.-P., Hill, D. F., Costa, M. E., Felder, S. and Ojeda, S. R. (1993) J. Neurosci., 13, 703-713.
42. Davideau, J.-L., Sahlberg, C., Blin, C., Papagerakis, P., Thesleff, I. and Berdal, A. (1995) Int. J. Dev. Biol., 39, 605-615.
43. Kagayama, R., Merlino, G. T. and Pastan, I. (1988) J. Biol. Chem., 263, 6329-6336.