Regulation of carcinoembryonic antigen expression in human colon carcinoma cells by the organ microenvironment

American Journal of Pathology

Volumn 149, Issue 4, 1996, Pages 1157-1166

  Kitadai, Yasuhiko ^a   Radinsky, Robert ^a   Bucana, Corazon D ^a   Takahashi, Yutaka ^a   Xie, Keping ^a   Tahara, Eiichi ^b   Fidler, Isaiah J ^a,c  

^a UNIVERSITY OF TEXAS   (United States)

^b HIROSHIMA UNIV SCHOOL OF MEDICINE   (Japan)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOEMBRYONIC ANTIGEN;

ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; CANCER GROWTH; CELL DIFFERENTIATION; COLON CARCINOMA; CONTROLLED STUDY; ENVIRONMENT; GENE EXPRESSION REGULATION; HUMAN; HUMAN TISSUE; MALE; METASTASIS POTENTIAL; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL;

ANIMALS; CARCINOEMBRYONIC ANTIGEN; CARCINOMA; CELL COUNT; CELL DIVISION; COLONIC NEOPLASMS; CULTURE MEDIA, CONDITIONED; HUMANS; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; TUMOR CELLS, CULTURED;

EID: 0029834565     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. Gold P, Freedman SO: Demonstration of tumor-specific antigen in human colonic carcinoma by immunological tolerance and absorption techniques. J Exp Med 1965, 121:439-462
2. Steele G Jr, Zamcheck N: The use of carcinoembryonic antigen in the clinical management of patients with colorectal cancer. Cancer Detection Prevention 1985, 8:421-427
3. Jessup JM, Gallick GE: The biology of colorectal carcinoma. Curr Probl Cancer 1992, 16:261-328
4. Beauchemin N, Benchimol S, Cournoyer D, Fuks A, Stanners CP: Isolation and characterization of full-length functional cDNA clones for human CEA Mol Cell Biol 1987, 7:3221-3230
5. Barnett TR, Kretschmer A, Austen DA, Goebel SJ, Hart JT, Elting JJ, Kamarck ME: Carcinoembryonic antigens: alternative splicing accounts for the multiple mRNAs that code for novel members of the carcinoembryonic antigen family. J Cell Biol 1989, 108:267-276
6. Paxton R, Mooser G, Pande H, Lee TD, Shively JE: Sequence analysis of carcinoembryonic antigen: identification of glycosylation sites and homology with the immunoglobulin super gene family, Proc Natl Acad Sci USA 1987, 84:920-924
7. Zimmerman W, Ortlieb B, Friedrich R, von Kleist S: Isolation and characterization of cDNA clones encoding the human carcinoembryonic antigen reveal a highly conserved repeating structure Proc Natl Acad Sci USA 1987, 84:2960-2964
8. Benchimol S, Fuks A, Jothy S, Beauchemin N, Shirota K, Stanners CP: Carcinoembryonic antigen, a human tumor marker, functions as an intercellular adhesion molecule. Cell 1989, 57:327-334
9. Liotta LA, Kleinerman J, Saidel GM: The significance of hematogenous tumor cell clumps in the metastatic process. Cancer Res 1976, 36:889-894
10. Wagner HE, Toth GA, Steele GD Jr, Thomas P: Metastatic potential of human colon cancer cell lines: relationship to cellular differentiation and carcinoembryonic antigen production. Exp Metastasis 1992, 10: 25-31
11. Tibbetts LM, Doremus CM, Tzanakakis GN, Vezeridis MP: Liver metastasis with 10 human colon carcinoma cell lines in nude mice and association with carcinoembryonic antigen production. Cancer 1993, 71:315-321
12. Hauck W, Stanners CP: Transcriptional regulation of the carcinoembryonic antigen gene. J Biol Chem 1995, 270:3602-3610
13. Radinsky R, Risin S, Fan D, Dong Z, Bielenberg D, Bucana CD, Fidler IJ: Level and function of epidermal growth factor receptor predict the metastatic potential of human colon carcinoma cells. Clin Cancer Res 1995, 1:19-31
14. Nakajima M, Morikawa K, Fabra A, Bucana CD, Fidler IJ: Influence of the organ environment on extracellular matrix degradative activity and metastasis of human colon carcinoma cells. J Natl Cancer Inst 1990, 82: 1890-1898
15. Fabra A, Nakajima M, Bucana CD, Fidler IJ: Modulation of the invasive phenotype of human colon carcinoma cells by organ-specific fibroblasts of nude mice. Differentiation 1992, 52:101-110
16. Singh RK, Bucana CD, Gutman M, Fan D, Wilson MR, Fidler IJ: The influence of the organ microenvironment on the expression of basic fibroblast growth factor in human renal cell carcinoma cells. Am J Pathol 1994, 145:365-374
17. Gutman M, Singh RK, Xie K, Bucana CD, Fidler IJ: Regulation of interleukin-8 expression in human melanoma cells by the organ environment. Cancer Res 1995, 55:2470-2475
18. Dong Z, Radinsky R, Fan D, Tsan R, Bucana CD, Wilmanns C, Fidler IJ: Organ-specific modulation of steady-state mdr-1 gene expression and drug resistance in murine colon cancer cells. J Natl Cancer Inst 1994, 86:913-920
19. Radinsky R, Fidler IJ, Price JE, Esumi N, Tsan R, Petty CM, Bucana CD, Bar-Eli M: Terminal differentiation and apoptosis in experimental lung metastases of human osteogenic sarcoma cells by wild-type p53. Oncogene 1994, 9:1877-1883
20. Toribara NW, Sack TL, Gum JR, Ho SB, Shively JE, Willson JKV, Kim YS: Heterogeneity in the induction and expression of carcinoembryonic antigen-related antigens in human colon cancer cell lines. Cancer Res 1989, 49:3321-3327
21. Chakrabarty S, Chen JW-J, Chen X, Trujillo JM, Lin P: Modulation of differentiation-related response in human colon carcinoma cells by protein kinase inhibitor H-7. Anticancer Res 1992, 12:97-104
22. Morikawa K, Walker SM, Jessup JM, Fidler IJ: In vivo selection of highly metastatic cells from surgical specimens of different human colon carcinomas implanted into nude mice: Cancer Res 1988, 1948, 48:1943
23. Morikawa K, Walker SM, Nakajima M, Pathak S, Jessup JM, Fidler IJ: The influence of the organ environment on the growth, selection, and metastasis of human colon cancer cells in nude mice. Cancer Res 1988, 48:6863-6871
24. Kobayashi H, Man S, Graham CH, Kapitain SJ, Teicher BA, Kerbel RS: Acquired multicellular-mediated resistance to alkylating agents in cancer. Proc Natl Acad Sci USA 1993, 90:3294-3298
25. Radinsky R, Kraemer PM, Raines MA, Kung HJ, Gulp LA: Amplification and rearrangement of Kirsten ras oncogene in virus transformed BALB/c 3T3 cells during malignant tumor progression. Proc Natl Acad Sci USA 1987, 84:5143-5147
26. Fort P, Marty L, Liechaczyk M, Sabrouty SE, Dani C. Blanchard JM: Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphatidehydrogenase multigene family. Nucleic Acid Res 1985, 13:1431-1442
27. Feinberg AP, Vogelstein B: A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal Biochem 1983, 132:6-13
28. Murphy PR, Sato R, Sato Y, Friesen HG: Fibroblast growth factor messenger ribonucleic acid expression in a human astrocytoma cell line: regulation of serum and cell density. Mol Endonucl 1988, 2:591-598
29. Xie B, Bucana CD, Fidler IJ: Density-dependent induction of 92-kd type IV collagenase activity in cultures of A431 human epidermoid carcinoma cells. Am J Pathol 1994, 144:1058-1067
30. Hauptmann S, Denkert C, Löhrke H, Tietze L, Ott S, Klosterhalfen B, Mittermayer C: Integrin expression on colorectal tumor cells growing as monolayers, as multicellular tumor spheroids, or in nude mice, Int J Cancer 1995, 61:819-825
31. Fogh J, Fogh JM, Orfeo T: One hundred and twenty-seven cultured human tumor cell lines producing tumors in nude mice. J Natl Cancer Inst 1977, 59:221-225
32. Pinto M, Robine-Leon S, Appay M-D, Kedinger M, Triadou N, Dussaulx E, Lacroix B, Simon-Assmann P, Haffen K, Fogh J, Zweibaum A: Enterocyte-like differentiation and polarization of the human colon carcinoma cell line Caco-2 in culture, Biol Cell 1983, 47: 323-330
33. Tomasz M, Lipman R, Chowdary D, Pawlak J, Verdine GL, Nakamishi K: Isolation and structure of covalent crosslink adduct between mitomycin C and DNA. Science 1987, 235:1204-1208
34. Paget S: The distribution of secondary growth in cancer of the breast. Lancet 1889, 1:571-573
35. Mulder KM: Differential regulation of c-myc and transforming growth factor-α messenger RNA expression in poorly differentiated and well differentiated colon carcinoma cells during the establishment of a quiescent state. Cancer Res 1991, 51:2256-2262
36. Williams GM, Stromberg K, Kroes R: Cytochemical and ultrastructural alterations associated with confluent growth in cell cultures of epithelial-like cells from rat liver. Lab Invest 1973, 29:293-303
37. Hauck W, Stanners CP: Control of carcinoembryonic antigen gene family expression in a differentiating colon carcinoma cell line, Caco-2. Cancer Res 1991, 51:3526-3533
38. Chakrabarty S, Jan Y, Brattain MG, Tobon A, Varani J: Diverse cellular response elicited from human colon carcinoma cells by transforming growth factor-β. Cancer Res 1989, 49:2112-2117
39. Chakrabarty S, Fan D, Varani J: Modulation of differentiation and proliferation in human colon carcinoma cells by transforming growth factor β1 and β2. Int J Cancer 1990, 46:493-499
40. Guadagni F, Witt PL, Robbins PF, Schlom J, Greiner JW: Regulation of carcinoembryonic antigen expression in different human colorectal tumor cells by Interferon-γ. Cancer Res 1990, 50:6248-6255
41. Kanai T, Hibi T, Hayashi A, Takashima J, Shiozawa M, Also S, Toda K, Iwao Y, Watanabe M, Tsuchiya M: Carcinoembryonic antigen mediates in vitro cell aggregation induced by interferon-γ in a human colon cancer cell line: requirement for active metabolism and intact cytoskeleton. Cancer Lett 1993, 71:109-117