A comparison of the ultrastructure of perfusion-deficient and functional lung parenchyma in CBA mice during the late phase after irradiation

Radiation Research

Volumn 146, Issue 5, 1996, Pages 586-589

  Franko, Allan J ^a   Nguyen, Gia Khanh ^b   Sharplin, Janet ^a   Vriend, Richard ^b  

^a CROSS CANCER INSTITUTE   (Canada)

^b UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON COLLOID; COLLAGEN FIBER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CAPILLARY ENDOTHELIUM; CONTROLLED STUDY; LUNG INTERSTITIUM; LUNG PARENCHYMA; LUNG PERFUSION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSMISSION ELECTRON MICROSCOPY; ULTRASTRUCTURE; X IRRADIATION;

ANIMALS; LUNG; MALE; MICE; MICE, INBRED C3H; MICE, INBRED CBA; MICROSCOPY, ELECTRON; PERFUSION;

ANIMALIA;

EID: 0029834414     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.2307/3579561     Document Type: Article

References (18)

1. J. Sharplin and A. J. Franko, A quantitative histological study of strain-dependent differences in the effects of irradiation on mouse lung during the intermediate and late phases. Radiat. Res. 119, 15-31 (1989).
2. E. L. Travis, M. L. Meistrich, M. V. Finch-Neimeyer, T. L. Watkins and I. Kiss, Late functional and biochemical changes in mouse lung after irradiation: Differential effects of WR-2721. Radiat. Res. 103, 219-231 (1985).
3. J. D. Down and G. G. Steel, The expression of early and late damage after thoracic irradiation: A comparison between CBA and C57BI mice. Radiat. Res. 96, 603-610 (1983).
4. C. H. Collis and G. G. Steel, Dose-dependence of the time of appearance of lung damage in mice given thoracic irradiation. Int. J. Radiat. Biol. 42, 345-352 (1982).
5. J. D. Down, The nature and relevance of late lung pathology following localized irradiation of the thorax in mice and rats. Br. J. Cancer 53 (Suppl. VII), 330-332 (1986).
6. R. L. Karvonen, F. Fernandez-Madrid, R. L. Maughan, K. C. Palmer and I. Fernandez-Madrid, An animal model of pulmonary radiation fibrosis with biochemical, physiologic, immunologic, and morphological observations. Radiat. Res. 111, 68-80 (1987).
7. J. C. Murray and C. S. Parkins, Collagen metabolism in mouse lung after X irradiation. Radiat. Res. 111, 498-510 (1987).
8. C. D. Port and W. F. Ward, The ultrastructure of radiation injury in rat lung: Modification by D-penicillamine. Radiat. Res. 92, 61-82 (1982).
9. J. R. Maisin, The ultrastructure of the lung of mice exposed to a supralethal dose of radiation on the thorax. Radiat. Res. 44, 545-564 (1970).
10. 60Co radiation pneumonitis in rats. Lab. Invest. 28, 545-553 (1973).
11. E. L. Travis, C. S. Parkins, S. J. Holmes and J. D. Down, Effect of misonidazole on radiation injury to mouse spinal cord. Br. J. Cancer 45, 469-473 (1982).
12. A. J. Franko and J. Sharplin, Assessment of radiation-induced lung injury in mice using carbon monoxide uptake: Correlation with histologically visible damage. Radiat. Res. 133, 245-251 (1993).
13. J. Bell, D. McGivern, J. Bullimore, J. Hill, E. R. Davies and P. Goddard, Diagnostic imaging of post-irradiation changes in the chest. Clin. Radiol. 39, 109-119 (1988).
14. G. G. Miller, J. Sharplin and A. J. Franko, Immunohistochemical quantitation of three collagen isotypes in perfused areas and nonperfused foci of the lungs of irradiated mice. Radiat. Res. 119. 32-38 (1989).
15. L. Kwock, W. C. Davenport, R. L. Clark, J. Zarembra, B. Lingle, E. L. Chancy and M. Friedman, The effects of ionizing radiation on the pulmonary vasculature of intact rats and isolated pulmonary endothelium. Radiat. Res. 111, 276-291 (1987).
16. E. A. Perkett, K. L. Brigham and B. Meyrick, Increased vasoreactivity and chronic pulmonary hypertension following thoracic irradiation in sheep. J. Appl. Physiol. 61, 1875-1881 (1986).
17. J. Sharplin and A. J. Franko, A quantitative histological study of strain-dependent differences in the effects of irradiation on mouse lung during the early phase. Radiat. Res. 119, 1-14 (1989).
18. M. L. Guerry-Force, E. A. Perkett, K. L. Brigham and B. Meyrick, Early structural changes in sheep lung following thoracic irradiation. Radiat. Res. 114, 138-153 (1988).