Intravenous carboplatin for recurrent gliomas: A dose-escalating phase II trial

American Journal of Clinical Oncology: Cancer Clinical Trials

Volumn 19, Issue 6, 1996, Pages 609-612

  Prados, Michael D ^a   Warnick, Ronald E ^a   Mack, Ellen E ^a   Chandler, Kym L ^a   Rabbitt, Jane ^a   Page, Margaretta ^a   Malec, Mary ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Carboplatin; Chemotherapy; Glioma; Survival

Indexed keywords

CARBOPLATIN; STEROID;

ADOLESCENT; ADULT; ARTICLE; BLOOD TOXICITY; CANCER SURVIVAL; CHILD; CLINICAL TRIAL; FEMALE; GLIOBLASTOMA; GLIOMA; HUMAN; INFANT; INTRAVENOUS DRUG ADMINISTRATION; MAJOR CLINICAL STUDY; MALE; NEUROLOGIC EXAMINATION; NUCLEAR MAGNETIC RESONANCE IMAGING; PHASE 2 CLINICAL TRIAL; THROMBOCYTE COUNT; TUMOR GROWTH;

ADOLESCENT; ADULT; AGED; ANTINEOPLASTIC AGENTS; BRAIN NEOPLASMS; CARBOPLATIN; CHILD; CHILD, PRESCHOOL; DISEASE PROGRESSION; DRUG ADMINISTRATION SCHEDULE; FEMALE; GLIOBLASTOMA; GLIOMA; HUMANS; INFANT; INFUSIONS, INTRAVENOUS; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; NEUTROPENIA; REMISSION INDUCTION; SURVIVAL RATE; THROMBOCYTOPENIA;

EID: 0029834063     PISSN: 02773732     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000421-199612000-00016     Document Type: Article

References (15)

1. Shapiro WR, Shapiro JR. Principles of brain tumor chemotherapy. Semin Oncol 1986;13:56-69.
2. Kornblith PL, Walker M. Chemotherapy for malignant gliomas. J Neurosurg 1988;68:1-17.
3. Prados MD, Levin VA, Hoshino T, Wilson CB. Chemotherapy of brain tumors. In: Youmans JR, ed. Neurological surgery. Vol 5. 3rd ed. Philadelphia: Saunders, 1990:3412-25.
4. Walker RW, Allen JC. Cisplatin in the treatment of recurrent childhood primary brain tumors. J Clin Oncol 1988;6:62-6.
5. Mahaley MS Jr, Hipp SW, Dropcho EJ, et al. Intracarotid cis-platin chemotherapy for recurrent gliomas. J Neurosurg 1989;70:371-8.
6. Allen JC, Walker R, Luks E, Jennings M, Barfoot S, Tan C. Carboplatin and recurrent childhood brain tumors. J Clin Oncol 1987;5:459-63.
7. Walker RW. Carboplatin (CBDCA) in the treatment of recurrent glioma. Neurology 1988;38:390-1.
8. Yung WKA, Mechtler L, Gleason MJ. Intravenous carboplatin for recurrent malignant glioma: a phase II study. J Clin Oncol 1991;9:860-4.
9. Warnick RE, Prados MD, Mack EE, et al. A phase II study of intravenous carboplatin for the treatment of recurrent gliomas. J Neurooncol 1994;19:69-74.
10. Kaplan EL, Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc 1958;53:457-81.
11. Stewart DJ, Belanger JMEG, Grahovac Z, et al. Phase I study of intracarotid administration of carboplatin. Neurosurgery 1992;30:512-7.
12. Follezou JY, Fauchon F, Chiras J. Intraarterial infusion of car- boplatin in the treatment of malignant gliomas: a phase II study. Neoplasma 1989;36:349-52.
13. Bacha DM, Caparros-Sison B, Allen JA, Walker R, Tan CTC. Phase I study of carboplatin (CBDCA) in children with cancer. Cancer Treat Rep 1986;70:865-9.
14. Calvert AH, Newell DR, Gumbrell LA, et al. Carboplatin dosage: prospective evaluation of a simple formula based on renal function. J Clin Oncol 1989;7:1748-56.
15. Egorin MJ, Van Echo DA, Olman EA, Whitacre MY, Forrest A, Aisner J. Prospective validation of a pharmacologically based dosing scheme for the cis-diamminedichloroplatinum (II) analogue diamminecyclobutane-dicarboxylatoplatinum. Cancer Res 1985;45:6502-6.