2B1 antigen characteristically expressed on extracellular matrices of human malignant tumors is a large chondroitin sulfate proteoglycan, PG- M/versican

Cancer Research

Volumn 56, Issue 17, 1996, Pages 3902-3908

  Isogai, Zenzo ^b   Shinomura, Tamayuki ^a   Yamakawa, Naomi ^a   Takeuchi, Jun ^c   Tsuji, Takuo ^b   Heinegård, Dick ^d   Kimata, Koji ^a  

^a AICHI MEDICAL UNIVERSITY   (Japan)

^b NAGOYA CITY UNIV MEDICAL SCHOOL   (Japan)

^c NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d LUND UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN 2 B 1; PROTEOCHONDROITIN SULFATE; UNCLASSIFIED DRUG; VERSICAN;

AMINO ACID SEQUENCE; ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; DNA TRANSFECTION; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; L CELL; MALIGNANT FIBROUS HISTIOCYTOMA; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, NEOPLASM; CELL ADHESION MOLECULES; CENTRIFUGATION; CULTURE MEDIA, CONDITIONED; DNA, COMPLEMENTARY; EPITOPES; EXTRACELLULAR MATRIX; HISTIOCYTOMA, BENIGN FIBROUS; HUMANS; HYALURONOGLUCOSAMINIDASE; LECTINS, C-TYPE; MICE; MOLECULAR SEQUENCE DATA; PRECIPITIN TESTS; PROTEOCHONDROITIN SULFATES; PROTEOGLYCANS; SEQUENCE HOMOLOGY, AMINO ACID; VERSICANS;

EID: 0029833998     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (49)

1. Iozzo, R. V., and Cohen, I Altered proteoglycan gene expression and the tumor stroma. Experimentia, 49: 447-455, 1993.
2. Wight, T. N., Heinegård, D K , and Hascall, V. C Proteoglycans: structure and function In: E. D Hay (eds.), Cell Biology of Extracellular Matrix, pp 45-78. New York: Plenum Publishing Corp., 1991.
3. Habucht, H , Suzuki, S., Saito, T., Tamura, T., Harada, T., Yoshida, K., and Kimata, K Structure of a heparan sulfate oligosaccharide that binds to a basic fibroblast growth factor. Biochem J , 285: 805-813, 1992.
4. LeBaron, R G , Zimmermann, D. R., and Ruoslahti, E. Hyaluronate binding properties of versican J Biol. Chem., 267 10003-10010, 1992
5. Yamada, H., Watanabe, K , Shimonaka, M., and Yamaguchi, Y. Molecular cloning of brevican, a novel brain proteoglycan of the aggrecan/versican family. J. Biol. Chem., 269 10119-10126, 1994.
6. Rauch, U , Karthikeyan, L., Maurel, P , Margolis, R. U , and Margolis, R K. Cloning and primary structure of neurocan, a developmentally regulated, aggregating chondroitin sulfate proteoglycan of brain J. Biol. Chem , 207: 19536-19547, 1992.
7. Heinegård, D , and Sommarin, Y Isolation and characterization of proteoglycans. Methods Enzymol., 144, 319-372, 1987.
8. Yamagata, M., Suzuki, S., Akiyama, S. K., Yamada, K. M., and Kimata, K. Regulation of cell-substrate adhesion by proteoglycans immobilized on extracellular substrates J. Biol Chem., 264: 8012-8018, 1989.
9. Yamagata, M., Yamada, K M., Yoneda, M., Suzuki, S., and Kimata, K. Chondroitin sulfate proteoglycan (PG-M-like proteoglycan) is involved in the binding of hyaluronic acid to cellular fibronectin. J Biol. Chem., 261: 13526-13535, 1986.
10. Yeo, T-K., Brown, L., and Dvorak, H. F Alterations in proteoglycan synthesis common to healing wounds and tumors. Am. J Pathol , 138: 1437-1450, 1991
11. Sobue, M., Takeuchi, J., Yoshida, K , Akao, S , Fukatsu, T , Nagasaka, T , and Nakashima, N. Isolation and characterization of proteoglycans from human nonepithelial tumors. Cancer Res., 47: 160-168, 1987.
12. Alini, M., and Losa, G. A. Partial characterization of proteoglycans isolated from neoplastic and nonneoplastic human breast tissues. Cancer Res , 51: 1443-1447, 1991.
13. Schrappe, M., Klier, F. G., Spiro, R C., Waltz, T A., Reisfeld, R. A , and Gladson, C. L. Correlation of chondroitin sulfate proteoglycan expression on proliferating brain capillary endothelial cells with the malignant phenotype of astroglial cells. Cancer Res , 51: 4986-4993, 1991
14. Sobue, M., Nakashima, N., Fukatsu, T., Nagasaka, T., Fukata, S , Ohiwa, N., Nara, Y , Ogura, T., Katoh, T., and Takeuchi, J Production and Immunohistochemical characterization of a monoclonal antibody raised to proteoglyean purified from a human yolk sac tumour Histochem. J , 21: 455-460, 1989
15. Nakashima, N., Sobue, M , Fukata, S., Fukatsu, T , Nagasaka, T , Ohiwa, N., Nara, Y., Lai, S., and Takeuchi, J. Immunohistochemical characterization of extracellular matrix components of yolk sac tumors. Virchows Arch. B Cell Pathol., 58: 203-208, 1990.
16. Ohiwa, N., Fukata, S., Fukatsu, T., Nagasaka, T., Nara, Y , Lai, S., Nakashima,. N., and Takeuchi, J Immunohistochemical localization of proteoglycans in non-epithelial tumor tissues. Connect Tissue, 22: 11-19, 1991.
17. Heinegård, D , Bjorne-Persson, A , Cöster, L., Franzén, A , Gardell, S , Malmström A , Paulsson, M., Sandfalk, R , and Vogel, K The core proteins of large and small interstitial proteoglycans from various connective tissues from distinct subgroups Biochem. J , 230: 181-194, 1985
18. Shinomura, T., Nishida, Y., Ito, K., and Kimata, K. cDNA cloning of PG-M, a large chondroitin sulfate proteoglycan expressed during chondrogenesis in chick limb buds. J Biol. Chem., 268: 14461-14469, 1993.
19. Kanzaki, T , Kitajima, S., and Suzumori, K Biological behavior of cloned cells of human malignant fibrous histiocytoma in vivo and in vitro Cancer Res., 51: 2133-2137, 1991.
20. Morita, H., Takeuchi, T., Suzuki, S., Maeda, K., Yamada, K., Eguchi, G , and Kimata, K. Aortic endothelial cells synthesize a large chondroitin sulfate proteoglycan capable of binding to hyaluronate. Biochem J., 265: 61-68, 1990.
21. Kimura, J. H., Shinomura, T., and Thoner, E J-M. A Biosynthesis of cartilage proteoglycan and link protein Methods Enzymol., 144: 372-393, 1987.
22. Oike, Y., Kimata, K., Shinomura, T., Nakazawa, K., and Suzuki, S. Structural analysis of chick-embryo cartilage proteoglycan by selective degradation with chondroitin lyases (chondroitinases) and and endo-β-D-galactosidase (keratanase). Biochem. J., 191: 193-207, 1980.
23. Laememli, U. K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (Lond.), 227: 680-685, 1970.
24. Kato, M., Oike, Y , Suzuki, S., and Kimata, K. Selective removal of heparan sulfate chains from proteoheparan sulfate with a commercial preparation of heparitinase. Anal. Biochem., 148: 479-484, 1985.
25. Lowry, O H , Rosebrough, N J., Farr, A. L., and Randall, R. J. Protein measurement with the folin phenol reagent. J Biol Chem , 193: 265-275, 1951.
26. Bitter, T., and Muir, H. M. A modified uronic acid carbazole reaction. Anal. Biochem., 4: 330-334, 1962.
27. Towbin, H., Staehelin T., and Gordon, J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications Proc. Natl Acad. Sci USA, 76: 4350-4354, 1979.
28. Cleveland, D. W , Fischer, S G., Kirschner, M. W., and Laemmli, U. K. Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis J Biol Chem , 252: 1102-1106, 1977.
29. Matsudaira, P. Sequence from picornole quantities of proteins electroblotted onto polyvinylidine difluoride membranes J Biol Chem., 262: 10035-10038, 1987.
30. Zako, M., Shinomura, T , Ujita, M , Ito, K., and Kimata, K Expression of PG-M(V3), an alternatively spliced form of PG-M without a chondroitin sulfate attachment region in mouse and human tissues. J. Biol Chem., 270: 3914-3918, 1995
31. Yamagata, M., Saga, S , Kato, M., Bernfield, M., and Kimata, K. Selective distributions of proteoglycans and their ligands in pericellular matrix of cultured fibloblasts, implications for their roles in cell-substratum adhesion J. Cell Sci., 106 55-65, 1993
32. Kimata, K , Oike, Y., Tani, K , Shinomura, T , Yamagata, M , Uritani, M., and Suzuki, S. A large chondroitin sulfate proteoglycan (PG-M) synthesized before chondrogenesis in the limb bud of chick embryo J Biol. Chem., 261: 13517-13525, 1986.
33. Shinomura, T., Zako, M., Ito, K., Ujita, M , and Kimata, K. The gene structure and organization of mouse PG-M, a large chondroitin sulfate proteoglycan J. Biol Chem., 270: 10328-10333, 1995.
34. Ito, K., Shinomura, T., Zako, M., Ujita, M., and Kimata, K. Multiple forms of mouse PG-M, a large chondroitin sulfate proteoglycan generated by alternative splicing. J. Biol. Chem., 270: 958-965, 1995.
35. Dours-Zimmermann, M. T., and Zimmermann. D R. A. Novel glycosaminoglycan attachment domain identified in two alternative splice variants of human versican. J. Biol. Chem., 269: 32992-32998, 1994.
36. Zimmermann, D. R., Dours-Zimmermann, M. T., Schubert, M., and Bruckner-Tuderman, L. Versican is expressed in the proliferating zone in the epidermis and in association with the elastic network of the dermis J. Cell Biol., 124: 817-825, 1994.
37. Yamagata, M., and Kimata, K. Repression of a malignant cell-substratum adhesion phenotype by inhibiting the production of the anti-adhesive proteoglycan, PG-M/versican. J Cell Sci., 107: 2581-2590, 1994.
38. Naso, M. F., Zimmermann, D R., and Iozzo, R. V Characterization of the complete genomic structure of the human versican gene and functional analysis of its promoter. J. Biol. Chem , 269: 32999-33008, 1994.
39. Fukata, S., Fukatsu, T., Nagasaka, T , Ohiwa, N , Nara, Y., Nakashima, N., Sobue, M , and Takeuchi, J Immunohistochemical localization of proteoglycans in interstitial elements of human pancreas and biliary system. Histochem. J., 21: 707-714, 1989.
40. Zimmermann, D. R., and Ruoslahti, E. Multiple domains of the large fibroblast proteoglycan, versican. EMBO J., 8: 2975-2981, 1989.
41. Ujita, M., Shinomura, T., Ito, K., Kitagawa, Y., and Kimata, K. Expression and binding activity of the carboxyl-terminal portion of the core protein of PG-M, a large chondroitin sulfate proteoglycan. J. Biol. Chem., 269, 27603-27609, 1994.
42. Takeuchi, J., Sobue, M., Sato, E., Shamoto, M , Miura, K., and Nakagaki, S Variation in glycosaminoglycan components of breast tumors. Cancer Res., 36 2133-2139, 1976.
43. Kimata, K., Honma, Y., Okayama, M., Oguri, K., Hozumi, M., and Suzuki, S. Increased synthesis of hyaluronic acid by mouse mammary carcinoma cell variants with high metastatic potential. Cancer Res., 43: 1347-1354, 1983.
44. Shinomura, T., Jensen, K L., Yamagata, M., Kimata, K , and Solursh, M. The distribution of mesenchyme proteoglycan (PG-M) during wing bud outgrowth. Anat. Embryol , 181: 227-233, 1990.
45. Toole, B. P. Proteoglycans and hyaluronan in morphogenesis and differentiation. In: E D. Hay (eds ), Cell Biology of Extracellular Matrix, pp. 305-341. New York Plenum Publishing Corp., 1991.
46. Yamagata, M., Shinomura, T , and Kimata, K. Tissue variation of two large chondroitin sulfate proteoglycans (PG-M/versican and PG-H/aggrecan) in chick embryos. Anat Embryol., 187: 433-444, 1993
47. Schönherr, E., Järveläainen, H. T., Sandell, L. J., and Wight, T N. Effects of platelet-derived growth factor and transforming growth factor-β1 on the synthesis of a large versican-like chondroitin sulfate proteoglycan by arterial smooth muscle cells J. Biol Chem., 266: 17640-17647, 1991.
48. Kähäri, V-M., Larjava, H., and Uitto, J. Differential regulation of extracellular matrix proteoglycan (PG) gene expression. J. Biol. Chem., 266: 10608-10615, 1991
49. Nishida, Y , Shinomura, T., Iwata, H , Miura, T , and Kimata, K. Abnormal occurrence of a large chondroitin sulfate proteoglycan, PG-M/versican, in osteoarthritic cartilage. Osteoarthritis Cartilage, 2: 43-49, 1994.