Saccharomyces cerevisiae mutants selected for increased production of Trichoderma reesei cellulases

Applied Microbiology and Biotechnology

Volumn 46, Issue 1, 1996, Pages 36-45

  Aho, S ^a,b   Arffman, A ^a,b   Korhola, M ^a,c  

^a Alko Inc   (Finland)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

^c UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

CELLULASE;

ARTICLE; CONTROLLED STUDY; ENZYME SYNTHESIS; FUNGUS MUTANT; MOLECULAR CLONING; NONHUMAN; SACCHAROMYCES CEREVISIAE; TRICHODERMA REESEI;

CELLULASE; CELLULOSE 1,4-BETA-CELLOBIOSIDASE; CROSSES, GENETIC; GENE EXPRESSION; MUTATION; RECOMBINANT FUSION PROTEINS; RNA, FUNGAL; RNA, MESSENGER; SACCHAROMYCES CEREVISIAE; TRICHODERMA;

FUNGI; HYPOCREA JECORINA; SACCHAROMYCES CEREVISIAE; TRICHODERMA;

EID: 0029833985     PISSN: 01757598     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002530050780     Document Type: Article

References (30)

1. Aho S (1991) Structural and functional analysis of Trichoderma reesei endoglucanase I expressed in yeast Saccharomyces cererisiae. FEBS Lett 291:45-49
2. Aho S, Olkkonen V, Jalava T, Paloheimo M, Bühler R, Niku-Paavola M-L, Bamford D, Korhola M (1991) Monoclonal antibodies against core and cellulose-binding domains of Trichoderma reesei cellobiohydrolases I and II and endoglucanase I. Eur J Biochem 200:643-649
3. Aho S, Paloheimo M (1990) The conserved terminal region of Trichoderma reesei cellulases forms a strong antigenic epitope for polyclonal antibodies. Biochim Biophys Acta 1087:137-141
4. Ammerer G (1983) Expression of genes in yeast using the ADC1 promoter. Methods Enzymol 101:192-201
5. Arffman A, Aho S, Torkkeli H, Korhola M (1990) Isolation and characterization of yeast mutants supersecreting Trichoderma reesei endoglucanase I (EGI). Yeast 6 (Special issue) S438
6. Biely P, Mislovicova D, Toman R (1985) Soluble chromogenic substrates for the assay of end(o-1,4-β-xylanases and endo-1,4-β-glucanases. Anal Biochem 144:142-146
7. Bühler R (1991) Double-antibody sandwich enzyme-linked immunosorbent assay for quantitation of endoglucanase I of Trichoderma reesei. Appl Environ Microbiol 57:3317-3321
8. Farkas V, Liskova M, Biely P (1985) Novel media detection of microbial producers of cellulase and xylanase. FEMS Microbiol Lett 28:137-140
9. Gancedo JM (1992) Carbon catabolite repression in yeast. Eur J Biochem 206:297-313
10. Hadfield C, Raina KK, Shashi-Menon K, Mount RC (1993) The expression and performance of cloned genes in yeasts (review). Mycol Res 97:897-944
11. Harkki A, Mäntylä A, Penttilä M, Muttilainen S, Bühler R, Suominen P, Knowles J, Nevalainen H (1991) Genetic engineering of Trichoderma to produce strains with novel cellulase profiles. Enzyme Microbial Technol 13:227-233
12. Ichikawa K, Shiba Y, Jigami Y, Serizawa N (1993) Secretion and overproduction of carboxypeptidase Y by a Saccharomyces cererisiae ssll mutant strain. Biosci Biotechnol Biochem 57: 1686-1690
13. Kaisho Y, Yoshimura K, Nakahama K (1989) Increase in gene expression by respiratory-deficient mutation. Yeast 5:91-98
14. Karhunen T, Mäntylä A, Nevalainen KMH, Suominen P (1993) High frequency one-step gene replacement in Trichoderma reesei. I. Endoglucanase l overproduction. Mol Gen Genet 241: 515-522
15. Nagasu T, Shimma Y, Nakanishi Y, Kuromitsu J. Iwama K, Nakayama K, Suzuki K, Jigami Y (1992) Isolation of new temperature-sensitive mutants of Saccharomyces cererisiae deficient in mannose outer chain elongation. Yeast 8:535-547
16. Nakayama K, Nagasu T, Shimma Y, Kuromitsu J, Jigami Y (1992) OCH1 encodes a novel membrane bound mannosyltransferase: outer chain elongation of asparagine-linked oligosaceharides. EMBO J 11:2511-2519
17. Penttilä ME, Andre L, Saloheimo M, Lehtovaara P, Knowles JKC (1987) Expression of two Trichoderma reesei endoglucanases in the yeast Saccharomyces cererisiae. Yeast 3: 175-185
18. 2+ ATPase family. Cell 58:133-145
19. Ruohonen L, Penttilä M, Keränen S (1991) Optimization of Bacillus α-amylase production by Saccharomyces cererisiae. Yeast 7: 337-347
20. Sakai A, Shimizu Y, Hishinuma F(1988) Isolation and characterization of mutants, which show an oversecretion phenotype in Saccharomyces cererisiae. Genetics 119:499-506
21. Sakai A, Shimizu Y, Kondou S, Chibazakura T, Hishinuma F (1990) Structure and molecular analysis of GRG1, a gene required for glucose repression of Saccharomyces cererisiae. Mol Cell Biol 10: 4130-4138
22. Sakai A, Chibazakura T, Shimizu Y, Hishinuma F (1992) Molecular analysis of POP2 gene, a gene required for glucose-derepression of gene expression in Saccharomyces cererisiae. Nucleic Acids Res 20:6227-6233
23. Sherman F, Fink GR, Hicks JB (1986) Laboratory course manual for methods in yeast genetics. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York
24. Smith RA, Duncan MJ, Moir DT (1985) Heterologous protein secretion from yeast. Science 229:1219-1224
25. Suominen P (1988) Charactrization and applications of the yeast MEL1 gene. PhD thesis, Department of Genetics, University of Helsinki, Finland
26. Suominen PL, Mäntylä AL, Karhunen T, Hakola S, Nevalainen H (1993) High frequency one-step gene replacement in Trichoderma reesei. II. Effects of deletions of individual cellulase genes. Mol Gen Genet 241:523-530
27. Suzuki K, Ichikawa K, Jigami Y (1989) Yeast mutants with enhanced ability to secrete human lysozyme: isolation and identification of a protease deficient mutant. Mol Gen Genet 219: 58-64
28. Tomme P, Van Tilbeurgh H, Petterson G, Van Damme, Vandekerckhove J, Knowles J, Teeri T, Claeyssens M (1988) Studies of the cellulolytic system of Trichoderma reesei QM 9414. Analysis of domain function in two cellobiohydrolases by limited proteolysis. Eur J Biochem 170:575-581
29. RPG) found initially in genes encoding ribosomal proteins. Gene 90:79-85
30. Zurbriggen B, Bailey MJ, Penttilä ME, Poutanen K, Linko M (1990) Pilot scale production of a heterologous Trichoderma reesei cellulase by Saccharomyces cererisiae. J Biotechnol 13: 267-278