Therapeutic efficacy of pamidronate in combination with chemotherapy to bone metastasis of breast cancer in a rat model

Surgical Oncology

Volumn 5, Issue 3, 1996, Pages 141-147

  Tamura, H ^a   Ishii, S ^a   Ikeda, T ^a   Wada, N ^a   Enomoto, K ^a   Kitajima, M ^a  

^a KAWASAKI MUNICIPAL HOSPITAL   (Japan)

Author keywords

Animal model; Bone metabolic markers; Bone metastasis; Breast cancer; Mitomycin C; Pamidronate

Indexed keywords

ALKALINE PHOSPHATASE BONE ISOENZYME; BISPHOSPHONIC ACID DERIVATIVE; CREATININE; MITOMYCIN C; OSTEOCALCIN; PAMIDRONIC ACID; PYRIDONE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE DESTRUCTION; BONE METABOLISM; BONE METASTASIS; BREAST ADENOCARCINOMA; BREAST CANCER; CANCER COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; HISTOLOGY; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; OSTEOCLAST; OSTEOLYSIS; PRIORITY JOURNAL; RAT; SPINE; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0029833812     PISSN: 09607404     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-7404(96)80014-4     Document Type: Article

References (22)

1. RE Coleman RD Rubens The clinical course of bone metastasis from breast cancer Br J Cancer 155 1987 61 66
2. CSB Galasko Mechanisms of bone destruction in the development of skeletal metastases Nature 263 7 1976 507 508
3. CSB Galasko Relationship of bone destruction in skeletal metastases to osteoclast activation and prostaglandins Nature 263 7 1976 508 510
4. B Krempien F Wingen T Eichmann Protective effects of a prophylactic treatment with the bisphosphonate 3-amino-1-hydroxypropane-1,1-bisphosphonic acid on the development of tumour osteopathies in the rat: experimental studies with the Walker carcinosarcoma 256 Oncology 45 1988 41 46
5. H Kawashima The effect of bisphosponate and bone metabolism T Fujita Osteoporosis—Diagnosis and Therapy 1995 Life Science Japan 397 408 (in Japanese)
6. 2MDP) on Rat macrophage-mediated bone resorption in vitro J Clin Invest 70 1982 927 933
7. PM Boonekamp JA Lianne van der Wee-Pals Two modes of action of bisphosphonates on osteoclastic resorption of mineralized matrix Bone Mineral 1 1986 27 39
8. JM Delaisse Y Eeckhout G Vaes Bisphosphonates and bone resorption: effects on collagenase and lysosomal enzyme excretion Life Sci 37 1985 2291 2296
9. F Wingen T Eichmann C Manegold Effects of new bisphosphonic acids on tumor-induced bone destruction in the rat J Cancer Res Clin Oncol 111 1986 35 41
10. A Jung J Bornand B Mermillod Inhibition by diphosphonates of bone resorption induced by the Walker tumour of the rat Cancer Res 44 1984 3007 3011
11. R Nemoto K Uchida M Tsutsumi A model of localized osteolysis induced by the MBT-2 tumor in mice and its responsiveness to etidronate disodium J Cancer Res Clin Oncol 113 1987 539 543
12. PG Conte PG Giannessi J Latreille Delayed progression of bone metastases with pamidronate therapy in breast cancer patients: A randomized, multicenter phase III trial Ann Oncol 5 Suppl. 7 1994 41 44
13. H Tamura S Ishii T Ikeda A novel animal model for bone metastasis of breast cancer Proc Am Assoc Cancer Res 34 1993 97
14. F Arguello RB Baggs CN Frantz A murine model of experimental metastasis to bone and bone marrow Cancer Res 48 1988 6876 6881
15. I Kjønniken A Nesland φ Fodstad Nude rat model for studying metastasis of human tumor cells to bone and bone marrow J Natl Cancer Inst 82 5 1990 408 412
16. D Uebelhart E Gineyts MC Chapuy Urinary excretion of pyridinium crosslinks: a new marker of bone resorption in metabolic bone disease Bone Mineral 8 1990 87 96
17. CR Paterson SP Robins JM Horobin Pyridinium crosslinks as markers of bone resorption in patients with breast cancer Br J Cancer 64 1991 884 886
18. N Yuhki J Hamada N Kuzumaki Metastatic ability and expression of c-fos oncogene in cell clones of a spontaneous rat mammary tumour Jpn J Cancer Res 77 1986 9 12
19. S Ishii M Kitajima Mechanisms of bone metastasis using an animal model Exp Med 12 8 1994 1050 1054 (in Japanese)
20. K Sekine H Horie K Hata Determination of pyridinoline and deoxypyridinoline in urine by high-performance liquid chromatography with fluorometric detection Rinsho Kagaku 21 1 1992 18 25
21. S Eto Y Nakano A Waki Drug therapies of hypercalcemia: bisphosphonate therapy Horumon to Rinsho 41 7 1993 63 70 (in Japanese)
22. T Fujita M Fukase Y Oohashi A comparative study of pamidronate disodium(AHPrBP) and elcatonin in the treatment of hypercalcaemia of malignancy Rinsho Iyaku 8 6 1992 1455 1472 (in Japanese)