Effect of six-month treatment with Ukrain on early osteoporosis induced by ovariectomy in rats. Part I: Preliminary studies of bone parameters

Drugs under Experimental and Clinical Research

Volumn 22, Issue 3-5, 1996, Pages 173-176

  Jagiello Wojtowicz E ^a   Kleinrok, Z ^a   Nowicky, J W ^c   Jablonski M ^b   Gorzelak, M ^b   Chodkowska, A ^a   Feldo, M ^a   Matuszek, B ^a  

^a MEDICAL UNIVERSITY OF LUBLIN   (Poland)

^b Medical Akademy ^*  (Poland)

^c Ukrainian Anti Cancer Institute   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHOROTHIOIC ACID DERIVATIVE; UKRAIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; BONE STRENGTH; CONTROLLED STUDY; FEMALE; FEMUR; HUMERUS; INTRAPERITONEAL DRUG ADMINISTRATION; NONHUMAN; OSTEOPOROSIS; OVARIECTOMY; RAT;

ALKALOIDS; ANIMALS; ANTINEOPLASTIC AGENTS; BERBERINE ALKALOIDS; BODY WEIGHT; BONE AND BONES; DRUG ADMINISTRATION SCHEDULE; FEMALE; OSTEOPOROSIS; OVARIECTOMY; PHENANTHRIDINES; RATS; RATS, WISTAR;

EID: 0029833519     PISSN: 03786501     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Hohenwarter O., Strutzenberger K., Katinger H., Liepins A., Nowicky J.W. Selective inhibition of in vitro cell growth by the antitumoral drug Ukrain, Drugs Exptl. Clin. Res., XVIII (Suppl.), 1, 1992.
2. Nowicky J.W. New immuno-stimulating anticancer preparation Ukrain. Proceedings 13th International Congress of Chemotherapy, Vienna, 28 August-2 September, 1983.
3. Nowicky J.W., Greif M., Hamier F., Hiesmayr W., Staub W. Biological activity of Ukrain in vitro and in vivo. Chemotherapia, 6, (Suppl. 2), 683, 1987.
4. Nowicky J.W., Manolakis G , Mieijer D., Vatanasapt V., Brzosko W.J. Ukrain both as an anticancer and immunoregulatory agent. Drugs Exptl. Clin. Res., XVIII (Suppl.), 51, 1992.
5. Lohninger A., Hamler F. Chelidonium majus L. (Ukrain) in the treatment of cancer patients. Drugs Exptl. Clin. Res., XVIII (Suppl.), 73, 1992.
6. Musianowicz J. et al. Clinical studies of Ukrain in terminal cancer patients (Phase II). Drugs Exptl. Clin. Res., XVIII (Suppl.), 45, 1992.
7. Kleinrok Z., Jagiełło-Wójtowicz E., Matuszek B. Chodkowska A. Basic pharmacological properties of thiophosphoric acid alkaloid derivatives from Chelidonium majus L. Polish. J. Pharmacol. Pharm., 44, 227, 1992.
8. Kleinrok Z., Jagiełło-Wójtowicz E., Nowicky J.W., Chodkowska A., Feldo M., Matuszek B. Some pharmacological properties of prolonged administration of Ukrain in rodents. Drugs Exptl. Clin. Res., XVIII (Suppl.), 93, 1992.
9. Jagiełło-Wójtowicz E., Kleinrok Z., Surmaczynska B., Baran E., Feldo M., Nowicky J.W. Effect of single and three months treatment with Ukrain on aminotranslerases (ALT and AST) and on the serum protein level in rodents. Drugs Exptl. Clin. Res., XVIII (Suppl.), 85, 1992.
10. Saville P.D. Changes in skeletal mass and fragility with castration in the rat: a model of osteoporosis. J. Am. Geriatr. Soc., 17, 155, 1969.
11. Wroński T.J., Schenck P.A., Cintron M., Walsh C.C. Effect of body weight on osteopenia in ovariectomized rats. Calcif. Tissue Int., 40, 155, 1987.
12. Togari A., Arai M., Hironaka M., Matsumolo S., Shinoda H. Effect of HEBP (1-hydroxyethylidene-1, 1-bisphosphonate) on experimental osteoporosis induced by ovariectomy in rats. Japan J. Pharmacol., 56, 177, 1991.
13. Jagiełło-Wojtowicz E., Kleinrok Z., Nowicky J.W., Chodkowska A., Feldo M., Surmaczynska B., Corzelak M., Jablonski M. Effect of six-month treatment with Ukrain on early osteoporosis induced by ovariectomy in rats. Part II. Preliminary studies of some parameters of peripheral blood Drugs Exptl. Clin. Res., XXII (Suppl.), 105-108, 1996
14. Jagiełło-Wojtowicz E., Kleinrok Z., Nowicky J.W., Baran E. Effect of six-month treatment with Ukrain on early osteoporosis induced by ovariectomy in rats. Part III. Preliminary studies of the levels of some hormones. Drugs Exptl. Clin. Res., XXII (Suppl.), 109-112, 1996.