Identification of the nucleotide substitution that generates the fourth polymorphic site in human deoxyribonuclease I (DNase I)

Human Genetics

Volumn 98, Issue 4, 1996, Pages 415-418

  Iida, Reiko ^a   Yasuda, Toshihiro ^b   Takeshita, Haruo ^a   Tsubota, Etsuko ^a   Yuasa, Isao ^c   Nakajima, Tamiko ^b   Kishi, Koichiro ^b  

^a UNIVERSITY OF FUKUI   (Japan)

^b GUNMA UNIVERSITY   (Japan)

^c TOTTORI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYRIBONUCLEASE I;

ALLELE; ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; DNA SEQUENCE; EXON; GENE AMPLIFICATION; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENOTYPE; HUMAN; HUMAN CELL; INHERITANCE; INTRON; MAJOR CLINICAL STUDY; NUCLEOTIDE SEQUENCE; PHENOTYPE; POLYMERASE CHAIN REACTION; POPULATION GENETICS; PRIORITY JOURNAL; PROTEIN POLYMORPHISM; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SINGLE STRAND CONFORMATION POLYMORPHISM;

BASE SEQUENCE; DEOXYRIBONUCLEASE I; DNA PRIMERS; EXONS; GENOTYPE; HUMANS; INTRONS; MOLECULAR SEQUENCE DATA; PHENOTYPE; POINT MUTATION; POLYMERASE CHAIN REACTION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL;

EID: 0029833509     PISSN: 03406717     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004390050231     Document Type: Article

References (13)

1. Iida R, Yasuda T, Kishi K (1987) Purification of a young age-related glycoprotein (Ugl-Y) from normal human urine. J Biochem 101: 357-363
2. Kishi K, Yasuda T, Awazu S, Mizuta K (1989) Genetic polymorphism of human urine deoxyribonuclease I. Hum Genet 81: 295-297
3. Kishi K, Yasuda T, Ikehara Y, Sato W, Iida R (1990) Human serum deoxyribonuclease I (DNase I) polymorphism: pattern similarities among isozymes from serum, urine, kidney, liver, and pancreas. Am J Hum Genet 47: 121-126
4. Mannherz HG, Peitsch MC, Zanotti S, Paddenberg R, Polzar B (1995) A new function for an old enzyme: the role of DNase I in apoptosis. Curr Top Microbiol Immunol 198: 161-174
5. Nadano D, Yasuda T, Kishi K (1993) Measurement of deoxyribonuclease I activity in human tissues and body fluids by a single radial enzyme-diffusion method. Clin Chem 39: 448-452
6. Peitsch MC, Polzar B, Stephan H, Crompton T, MacDonald HR, Mannherz HG, Tschopp J (1993) Characterization of the endogenous deoxyribonuclease involved in nuclear DNA degradation during apoptosis (programmed cell death). EMBO J 12: 371-377
7. Yasuda T, Mizuta K, Ikehara Y, Kishi K (1989) Genetic analysis of human deoxyribonuclease I by immunoblotting and the zymogram method following isoelectric focusing. Anal Biochem 183: 84-88
8. Yasuda T, Sawazaki K, Nadano D, Takeshita H, Nakanaga M, Kishi K (1993) Human seminal deoxyribonuclease I (DNase I): purification, enzymological and immunological characterization and origin. Clin Chim Acta 218: 5-16
9. Yasuda T, Nadano D, Iida R, Takeshita H, Lane SA, Callen DF, Kishi K (1995a) Chromosomal assignment of the human deoxyribonuclease I gene, DNASE1 (DNL1), to band 16p13.3 using the polymerase chain reaction. Cytogenet Cell Genet 70: 221-223
10. Yasuda T, Kishi K, Yanagawa Y, Yoshida A (1995b) Structure of the human deoxyribonuclease I (DNase I) gene: identification of the nucleotide substitution that generates its classical genetic polymorphism. Ann Hum Genet 59: 1-15
11. Yasuda T, Nadano D, Takeshita H, Tenjo E, Kishi K (1995c) Molecular analysis of the third allele of human deoxyribonuclease I polymorphism. Ann Hum Genet 59: 139-147
12. Yasuda T, Nadano D, Takeshita H, Tenjo E, Sawazaki K, Ootani M, Kishi K (1995d) The molecular basis for genetic polymorphism of human deoxyribonuclease I: identification of the nucleotide substitution that generates the fourth allele. FEBS Lett 359: 211-214
13. Yasuda T, Nadano D, Tenjo E, Takeshita H, Sawazaki K, Nakanaga M, Kishi K (1995e) Genotyping of human deoxyribonuclease I polymorphism by the polymerase chain reaction. Electrophoresis 16: 1889-1893