Organ-specific expression of the colon cancer antigen A33, a cell surface target for antibody-based therapy

International Journal of Oncology

Volumn 9, Issue 3, 1996, Pages 465-471

  Garin Chesa, Pilar ^a,d   Sakamoto, Junichi ^b   Welt, Sydney ^a   Real, Francisco X ^c   Rettig, Wolfgang J ^a   Old, Lloyd J ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b AICHI CANCER CENTER HOSPITAL   (Japan)

^c INST MUNIC D INVESTIGACIO MEDICA   (Spain)

^d BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

Author keywords

cell surface antigen; colorectal cancer; immunohistochemistry; intestinal differentiation; monoclonal antibody

Indexed keywords

CELL SURFACE PROTEIN; MONOCLONAL ANTIBODY; TUMOR ANTIGEN;

ANTIGEN EXPRESSION; ARTICLE; CELL SURFACE; COLORECTAL CANCER; DIGESTIVE SYSTEM CANCER; ESOPHAGUS CANCER; GASTROINTESTINAL TRACT; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INTESTINE MUCOSA; PANCREAS CANCER; PRIORITY JOURNAL; PROTEIN LOCALIZATION; STOMACH CANCER;

EID: 0029832918     PISSN: 10196439     EISSN: None     Source Type: Journal    
DOI: 10.3892/ijo.9.3.465     Document Type: Article

References (26)

1. Press OW, Eary JF, Appelbaum FR, Martin PJ, Badger CC, Nelp WB, Glenn S, Butchko G, Fisher D, Porter B, Matthews DC, Fisher LD and Bernstein ID: Radiolabeled-antibody therapy of B-cell lymphoma with autologous bone marrow support. N Engl J Med 329: 1219-1224, 1993.
2. 131I]anti-B1 (anti-CD20) antibody. N Engl J Med 329: 459-465, 1993.
3. Jurcic JG, Caron PC, Nikula TK, Papadopoulos EB, Finn RD, Gansow OA, Miller WH, Geerlings MW, Warrell RP, Larson SM and Scheinberg DA: Radiolabeled anti-CD33 monoclonal antibody M195 for myeloid leukemias. Cancer Res 55: 5908-5910, 1995.
4. Waldmann TA, Goldman CK, Bongiovanni KF, Sharrow SO, Davey MP, Cease KB, Greenberg SJ and Longo DL: Therapy of patients with human T-cell lymphotropic virus I-induced adult T-cell leukemia with anti-Tac, a monoclonal antibody to the receptor for interleukin-2. Blood 78: 1805-1816, 1988.
5. Riethmüller G, Schneider-Gaedicke E, Schlimok G, Schmiegel W, Raab R, Hoeffken K, Gruber R, Pichlmaier H, Hirche H, Pichlmayr R, Buggisch P, Witte J and German Cancer Aid 17-1A Study Group: Randomized trial of monoclonal antibody for adjuvant therapy of resected Dukes' C colorectal carcinoma. Lancet 343: 1177-1183, 1994.
6. Rettig WJ: Immunogenetics of cell surface antigens of human cancer. Curr Opin Immunol 4: 630-640, 1992.
7. Nilsson B: Antibody engineering. Curr Opin Struct Biol 5: 450-456, 1995.
8. Pai LH and Pastan I: The use of immunotoxins for cancer therapy. Eur J Cancer 29A: 1606-1609, 1993.
9. Shively JE and Beatty JD: CEA-related antigens: molecular biology and clinical significance. Crit Rev Oncol Hematol 2: 355-399, 1985.
10. Hakomori S-I: Possible functions of tumor-associated carbohydrate antigens. Curr Opin Immunol 3: 646-653, 1991.
11. Colcher D, Esteban J, Carrasquillo JA, et al: Complementation of intracavitary and intravenous administration of a monoclonal antibody (B72.3) in patients with carcinoma. Cancer Res 47: 4218-4224, 1987.
12. Mach J-P, Pelegrin A and Buchegger F: Imaging and therapy with monoclonal antibodies in non-hematopoietic tumors. Curr Opin Immunol 3: 685-693, 1991.
13. Oettgen HF, Rettig WJ, Lloyd KO and Old LJ: Serologic analysis of human cancer. In: Human Cancer Immunology I: Immunology and Allergy Clinics of North America. Oettgen HF (ed). Vol. 10 No. 4. WB Saunders Company, Philadelphia, 1990.
14. Welt S, Divgi CR, Real FX, Yeh SD, Garin-Chesa P, Finstad CL, Sakamoto J, Cohen A, Sigurdson ER, Kemeny N, Carswell EA, Oettgen HF and Old LJ: Quantitative analysis of antibody localization in human metastatic colon cancer: a phase I study of monoclonal antibody A33. J Clin Oncol 8: 1894-1906, 1990.
15. 131-labeled monoclonal antibody A33 in patients with advanced colon cancer. J Clin Oncol 12: 1561-1571, 1994.
16. 125-labeled monoclonal antibody A33 in patients with advanced colon cancer. J Clin Oncol (In press).
17. Garin-Chesa P, Campbell I, Saigo PE, Lewis JL Jr, Old LJ and Rettig WJ: Trophoblast and ovarian cancer antigen LK26: sensitivity and specificity in immunopathology and molecular characterization as a folate-binding protein. Am J Pathol 142: 557-567, 1993.
18. Scanlan MJ, Raj BKM, Calvo B, Garin-Chesa P, Sanz-Moncasi MP, Healey JH, Old LJ and Rettig WJ: Molecular cloning of fibroblast activation protein, a member of the senne protease family selectively expressed in stromal fibroblasts of epithelial cancers. Proc Natl Acad Sci USA 91: 5657-5661, 1994.
19. Stearns MW: Staging colonie and rectal cancer. Int Adv Surg Oncol 4: 189-208, 1981.
20. Real FX, Xu M, Vila MR and de Bolos C: Intestinal brushborder-associated enzymes: co-ordinated expression in colorectal cancer. Int J Cancer 51: 173-181, 1992.
21. Yoshiura K, Kamai Y, Ochiai A, Shimoyana Y, Sugimura T and Hirohashi S: Silencing of the E-cadherin invasion suppressor gene by CpG methylation in human carcinoma. Proc Natl Acad Sci USA 92: 7416-7419, 1995.
22. Schlossman S, Boumsell L, Gilks W, Harlan J, Kishimoto TC, et al (eds): Leukocyte typing V. Oxford University Press, Oxford, 1995.
23. Garin-Chesa P, Sanz-Moncasi MP, Campbell IG and Rettig WJ: Non-polarized expression of basal cell adhesion molecule B-CAM in epithelial ovarian cancers. Int J Oncol 5: 1261-1266, 1994.
24. Perez-Soler R, Donato NJ, Shin DM, Rosenblum MG, Zhang H-Z, Tornos C, Brewer H, Chan JC, Lee JS, Hong WK and Murray JL: Tumor epidermal growth factor receptor studies in patients with non-small-cell lung cancer or head and neck cancer treated with monoclonal antibody RG 83852. J Clin Oncol 12: 730-739, 1994.
25. Kaufmann R, Hainzl A, Sterry W, Alberti S and Klein CE: In vivo targeting of integrin receptors in human skin xenografts by intravenously applied antibodies. Arch Dermatol Res 286: 6-11, 1994.
26. 125I-labeled A33 monoclonal antibody across the cytosol by vesicular internalization. J Nucl Med (In press).