Comparison of bronchial challenge with ultrasonic nebulized distilled water and hypertonic saline in children with mild-to-moderate asthma

European Respiratory Journal

Volumn 9, Issue 9, 1996, Pages 1896-1901

  Wojnarowski, C ^a   Storm Van's Gravesande, K ^a   Riedler, J ^b   Eichler, I ^a   Gartner, C ^a   Frischer, T ^a  

^a ST ANNA CHILDREN S HOSPITAL   (Austria)

^b Children's Hospital Salzburg   (Austria)

Author keywords

Asthma; Bronchial provocation; Hypertonic saline; Ultrasonically nebulized distilled water

Indexed keywords

ARTICLE; ASTHMA; BRONCHUS HYPERREACTIVITY; CLINICAL ARTICLE; CLINICAL PROTOCOL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; FORCED EXPIRATORY VOLUME; HUMAN; LUNG FUNCTION TEST; MALE; PRIORITY JOURNAL; PROVOCATION TEST; SAFETY; SCHOOL CHILD;

EID: 0029832548     PISSN: 09031936     EISSN: None     Source Type: Journal    
DOI: 10.1183/09031936.96.09091896     Document Type: Article

References (25)

1. Burney PG, Chinn S, Rona RJ. Has the prevalence of asthma increased in children? Evidence from the national study of health and growth, 1973-1986. BMJ 1990; 300 (6735): 1306-1310.
2. Pearce N, Weiland S, Keil U, et al. Self-reported prevalence of asthma symptoms in children in Australia, England, Germany and New Zealand. Eur Respir J 1993; 6 (10): 1455-1461.
3. Pattemore PK, Asher MI, Harrison AC, Mitchell EA, Rea HH. The interrelationship among bronchial hyper-responsiveness, the diagnosis of asthma, and asthma symptoms. Am Rev Respir Dis 1990; 142 (3):549-554.
4. Smith CH, Anderson SD. Inhalation challenge using hypertonic saline in asthmatic subjects: a comparison with response to hyperpnoea, methacholine and water. Eur Respir J 1990; 3:144-151.
5. Eichler I, Götz M, Zarkovic J, Köfinger A. Distilled water challenges in asthmatic children. Chest 1992; 102:753-758.
6. Galdes-Sebaldt M, McLaughlin FJ, Levison H. Comparison of cold air, ultrasonic mist, and methacholine inhalations as tests of bronchial reactivity in normal and asthmatic children. J Pediatr 1985; 107:526-530.
7. Riedler J, Reade T, Dalton M, Holst D, Robertson C. Hypertonic saline challenge in an epidemiologic survey of asthma in children. Am J Respir Crit Care Med 1994; 150: 1632-1639.
8. Smith CM, Anderson SD. Inhalation provocation tests using nonisotonic aerosols. J Allergy Clin Immunol 1989; 84:781-790.
9. Bascom R, Bleeker ER. Bronchoconstriction induced by distilled water: sensitivity in asthmatics and relationship to exercise-induced bronchospasm. Am Rev Respir Dis 1986; 134:243-248.
10. Foresi A, Mattoli S, Corbo GM, Polidori G, Ciappi G. Comparison of bronchial response to ultrasonic nebulized distilled water, exercise and methacholine in asthma. Chest 1986; 90:822-826.
11. Makker HK, Holgate ST. Relationship of the hypertonic saline responsiveness of the airways to exercise-induced asthma symptom severity and to histamine or methacholine reactivity. Thorax 1993; 48:142-147.
12. Belcher NG, Lee TH, Rees PJ. Airway response to hypertonic saline, exercise and histamine challenges in bronchial asthma. Eur Respir J 1989; 2:44-48.
13. Studnicka MJ, Frischer T, Weiss ST, Dockery DW, Speizer FE, Neumann MG. Seasonal and allergenic predictors of bronchial responsiveness to distilled water. Am Rev Respir Dis 1993; 146 (6, Pt1): 1460-1466.
14. Zach M, Polgar G, Kump H, Kroisel P. Cold air challenge of airway hyperreactivity in children: practical application and theoretical aspects. Pediatr Res 1984; 18 (5):469-478.
15. Bardagi S, Agudo A, Gonzalez CA, Romero PV. Prevalence of exercise-induced airway narrowing in schoolchildren from a Mediterranean town. Am Rev Respir Dis 1993; 147(5): 1112-1115.
16. Frischer T, Studnicka M, Neumann M, Götz M. Determinants of airway response to challenge with distilled water in a population sample of children aged 7 to 10 years old. Chest 1992; 102:764-770.
17. American Thoracic Society Committee on Diagnostic Standards for Nontuberculous Disease. Definitions and clarification of chronic bronchitis, asthma, and pulmonary emphysema. Am Rev Respir Dis 1962; 85:762-769.
18. Österr. Gesellschaft für Lungenerkrankungen und Tbc. Arbeitsgemeinschaft für Atemphysiologie: Empfehlungen zur Standardisierung der inhalat. Provokationen zur Messung der unspez. bronchialen Reaktivität. Prax Klin Pneumol 1986, 40:356-364.
19. Donnelly WJ, Donnelly JE, Thong YH. Guidelines for maintenance treatment of childhood asthma: development of a score and system by multivariate cluster analysis. Soc Sci Med 1987; 24: 1033-1038.
20. American Thoracic Society. Standardization of spirometry: 1987 update. Am Rev Respir Dis 1987; Attachment 2: 1285-1298.
21. Zapletal A, Samanek M, Paul T. Lung function in children and adolescents: methods, reference values. Progr Respir Res 1987; 22:113-218.
22. Riedler J, Robertson CF. Effect of tidal volume on the output and particle size distribution of hypertonic saline from an ultrasonic nebulizer. Eur Respir J 1994; 7:998-1002.
23. Strachan DP. Repeatability of ventilatory function measurements in a population survey of 7 year old children. Thorax 1989; 44:474-479.
24. Daviskas E, Gonda I, Anderson SD. Local airway heat and water vapour losses. Respir Physiol 1991; 84:115-132.
25. Smith CM, Anderson SD, Black JL. Methacholine responsiveness increases after ultrasonic nebulized water but not after ultrasonic nebulized hypertonic saline. J Allergy Clin Immunol 1987; 79:85-92.