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Volumn 18, Issue 4, 1996, Pages 388-392

Stereoselectivity in drug metabolism and action: Effects of enzyme inhibition and induction

Author keywords

Drug metabolism; Induction; Inhibition; Stereoselectivity

Indexed keywords

CIMETIDINE; CYTOCHROME P450; HEXOBARBITAL; MEPHENYTOIN; PROPAFENONE; RIFAMPICIN; SULFINPYRAZONE; VERAPAMIL; WARFARIN;

EID: 0029832456     PISSN: 01634356     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007691-199608000-00013     Document Type: Conference Paper
Times cited : (18)

References (18)
  • 1
    • 0027523333 scopus 로고
    • Nonchiral, homochiral and composite chiral drugs
    • Ariens EJ. Nonchiral, homochiral and composite chiral drugs. Trends Pharmacol Sci 1993;14:68-75.
    • (1993) Trends Pharmacol Sci , vol.14 , pp. 68-75
    • Ariens, E.J.1
  • 3
    • 0025786589 scopus 로고
    • Age-dependent stereoselective increase in the oral clearance of hexobarbitone isomers caused by rifampicin
    • Smith DA, Chandler MHH, Shedlofsky SI, Wedlund PJ, Blouin RA. Age-dependent stereoselective increase in the oral clearance of hexobarbitone isomers caused by rifampicin. Br J Clin Pharmacol 1991;32:735-9.
    • (1991) Br J Clin Pharmacol , vol.32 , pp. 735-739
    • Smith, D.A.1    Chandler, M.H.H.2    Shedlofsky, S.I.3    Wedlund, P.J.4    Blouin, R.A.5
  • 4
    • 0025014594 scopus 로고
    • Tolbutamide and mephenytoin hydroxylation by human cytochrome P450s in the CYP2C subfamily
    • Relling MV, Aoyama T, Gonzalez FJ, Meyer UA. Tolbutamide and mephenytoin hydroxylation by human cytochrome P450s in the CYP2C subfamily. J Pharmacol Exp Ther 1990;252:442-7.
    • (1990) J Pharmacol Exp Ther , vol.252 , pp. 442-447
    • Relling, M.V.1    Aoyama, T.2    Gonzalez, F.J.3    Meyer, U.A.4
  • 5
    • 0019447990 scopus 로고
    • Effect of pentobarbital on the formation of diastereomeric oxazepam glucuronides in man: Analysis by high performance liquid chromatography
    • Seideman P, Ericsson Ö, Gröningsson K, von Bahr C. Effect of pentobarbital on the formation of diastereomeric oxazepam glucuronides in man: analysis by high performance liquid chromatography. Acta Pharmacol Toxicol Copenh 1981; 49:200-4.
    • (1981) Acta Pharmacol Toxicol Copenh , vol.49 , pp. 200-204
    • Seideman, P.1    Ericsson, Ö.2    Gröningsson, K.3    Von Bahr, C.4
  • 9
    • 0022183599 scopus 로고
    • Verapamil disposition - Effects of sulphinpyrazone and cimetidine
    • Wing LMH, Miners JO, Lillywhite KJ. Verapamil disposition - effects of sulphinpyrazone and cimetidine. Br J Clin Pharmacol 1985;19:385-91.
    • (1985) Br J Clin Pharmacol , vol.19 , pp. 385-391
    • Wing, L.M.H.1    Miners, J.O.2    Lillywhite, K.J.3
  • 10
    • 0025280062 scopus 로고
    • Interaction of verapamil and cimetidine: Stereochemical aspects of drug metabolism, drug disposition and drug action
    • Mikus G, Eichelbaum M, Fischer C, Gumulka S, Klotz U, Kroemer HK. Interaction of verapamil and cimetidine: stereochemical aspects of drug metabolism, drug disposition and drug action. J Pharmacol Exp Ther 1990;253:1042-8.
    • (1990) J Pharmacol Exp Ther , vol.253 , pp. 1042-1048
    • Mikus, G.1    Eichelbaum, M.2    Fischer, C.3    Gumulka, S.4    Klotz, U.5    Kroemer, H.K.6
  • 11
    • 0023248835 scopus 로고
    • Pharmacokinetic interactions of cimetidine 1987
    • Somogyi A, Muirhead M. Pharmacokinetic interactions of cimetidine 1987. Clin Pharmacokinet 1987;12:321-66.
    • (1987) Clin Pharmacokinet , vol.12 , pp. 321-366
    • Somogyi, A.1    Muirhead, M.2
  • 12
    • 0026519541 scopus 로고
    • Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: A role for P-4502C9 in the etiology of (S)-warfarin-drug interactions
    • Rettie AE, Korzekwa KR, Kunze KL, et al. Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin-drug interactions. Chem Res Toxicol 1992;5:54-9.
    • (1992) Chem Res Toxicol , vol.5 , pp. 54-59
    • Rettie, A.E.1    Korzekwa, K.R.2    Kunze, K.L.3
  • 13
    • 0023105521 scopus 로고
    • Comparative effects of ranitidine and cimetidine on the pharmacokinetics and pharmacodynamics of warfarin in man
    • Toon S, Hopkins KJ, Garstang FM, Rowland M. Comparative effects of ranitidine and cimetidine on the pharmacokinetics and pharmacodynamics of warfarin in man. Eur J Clin Pharmacol 1987;32:165-72.
    • (1987) Eur J Clin Pharmacol , vol.32 , pp. 165-172
    • Toon, S.1    Hopkins, K.J.2    Garstang, F.M.3    Rowland, M.4
  • 14
    • 0022655468 scopus 로고
    • The warfarin-sulfinpyrazone interaction: Stereochemical considerations
    • Toon S, Low LK, Gibaldi M, et al. The warfarin-sulfinpyrazone interaction: stereochemical considerations. Clin Pharmacol Ther 1986;39:15-24.
    • (1986) Clin Pharmacol Ther , vol.39 , pp. 15-24
    • Toon, S.1    Low, L.K.2    Gibaldi, M.3
  • 15
    • 0025823440 scopus 로고
    • Enantiomer/enantiomer interaction of (S)- And (R)-propafenone for cytochrome P450IID6-catalyzed 5-hydroxylation: In vitro evaluation of the mechanism
    • Kroemer HK, Fischer C, Meese CO, Eichelbaum M. Enantiomer/enantiomer interaction of (S)- and (R)-propafenone for cytochrome P450IID6-catalyzed 5-hydroxylation: in vitro evaluation of the mechanism. Mol Pharmacol 1991;40: 135-42.
    • (1991) Mol Pharmacol , vol.40 , pp. 135-142
    • Kroemer, H.K.1    Fischer, C.2    Meese, C.O.3    Eichelbaum, M.4
  • 16
    • 0024512026 scopus 로고
    • Stereoselective disposition and pharmacologic activity of propafenone enantiomers
    • Kroemer HK, Funck-Brentano C, Silberstein DJ, et al. Stereoselective disposition and pharmacologic activity of propafenone enantiomers. Circulation 1989;79:1068-76.
    • (1989) Circulation , vol.79 , pp. 1068-1076
    • Kroemer, H.K.1    Funck-Brentano, C.2    Silberstein, D.J.3
  • 17
    • 0028295436 scopus 로고
    • An enantiomer-enantiomer interaction of (S)-and (R)-propafenone modifies the effect of racemic drug therapy
    • Kroemer HK, Fromm MF, Bühl K, Terefe H, Blaschke G, Eichelbaum M. An enantiomer-enantiomer interaction of (S)-and (R)-propafenone modifies the effect of racemic drug therapy. Circulation 1994;89:2396-400.
    • (1994) Circulation , vol.89 , pp. 2396-2400
    • Kroemer, H.K.1    Fromm, M.F.2    Bühl, K.3    Terefe, H.4    Blaschke, G.5    Eichelbaum, M.6
  • 18
    • 0028344079 scopus 로고
    • Mirror, mirror on the wall... Stereochemistry in therapeutics
    • Roden DM. Mirror, mirror on the wall... Stereochemistry in therapeutics. Circulation 1994;89:2451-3.
    • (1994) Circulation , vol.89 , pp. 2451-2453
    • Roden, D.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.