Postsynthetic regulation of insulin-like growth factor-binding protein-3 by MCF-7 human breast cancer cells in culture

Breast Cancer Research and Treatment

Volumn 39, Issue 2, 1996, Pages 187-196

  Grimes, Randall W ^a   Manni, Andrea ^a   Hammond, James M ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

IGF binding proteins; Insulin like growth factors; MCF 7 human breast cancer cells; Proteolysis

Indexed keywords

HEPARIN; PROTEINASE; SOMATOMEDIN; SOMATOMEDIN BINDING PROTEIN 3;

ARTICLE; BINDING SITE; BREAST CANCER; CANCER CELL CULTURE; CELL PROLIFERATION; CELL SURFACE; CONTROLLED STUDY; CULTURE MEDIUM; FEMALE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION;

EID: 0029832278     PISSN: 01676806     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF01806185     Document Type: Article

References (34)

1. Ahmed SR, Manni A, Gray G. Hammond JM: Characterization and hormonal regulation of radioimmunoassayable IGF-I (insulin-like growth factor I) like activity and IGF-binding proteins secreted by human breast cancer cells. Anticancer Res 10: 1217-1224, 1990
2. Freed KA, Herington AC: Insulin-like growth factor-I and its autocrine role in growth of MCF-7 human breast cancer cells in culture. J Mol Endocrinol 3: 183-190, 1989
3. Cullen KJ, Lippman ME, Chow D, Hill S, Rosen N, Zwiebel JA: Insulin-like growth factor-II overexpression in MCF-7 cells induces phenotypic changes associated with malignant progression. Mol Endocrinol 6: 91-100, 1992
4. Yee D, Rosen N, Favoni RE, Cullen KJ: The insulin-like growth factors, their receptors, and their binding proteins in human breast cancer. Cancer Treat Res 53: 93-106, 1991
5. Cullen KJ, Allison A, Martire I, Ellis M, Singer C: Insulin-like growth factor expression in breast cancer epithelium and stroma. Breast Cancer Res Treat 22: 21-29, 1992
6. Rosenfeld RG, Lamson G, Pham H, Oh Y, Conover C, De Leon DD, Donovan SM, Ocrant I, Giudice L: Insulin-like growth factor-binding proteins. Recent Prog Horm Res 46: 99-163, 1990
7. McGuire WL Jr, Jackson JG, Figueroa JA, Shimasaki S, Powell DR, Yee D: Regulation of insulin-like growth factor-binding protein (IGFBP) expression by breast cancer cells: use of IGFBP-1 as an inhibitor of insulin-like growth factor action. J Natl Cancer Inst 84: 1336-1341, 1992
8. Pratt SE, Pollak MN: Insulin-like growth factor binding protein 3 (IGF-BP3) inhibits estrogen-stimulated breast cancer cell proliferation. Biochem Biophys Res Commun 198: 292-297, 1994
9. Schmid C, Rutishauser J, Schlapfer I, Froesch ER, Zapf J: Intact but not truncated insulin-like growth factor binding protein-3 (IGFBP-3) blocks IGF-I induced stimulation of osteoblasts: control of IGF signalling to bone cells by IGFBP-3-specific proteolysis? Biochem Biophys Res Commun 179: 579-585, 1991
10. Glikman PL, Manni A, Bartholomew M, Demers L: Polyamine involvement in basal and estradiol-stimulated insulin-like growth factor-I secretion and action in breast cancer cells in culture. J Steroid Biochem Molec Biol 37: 1-10, 1990
11. Oh Y, Muller HL. Lamson G, Rosenfeld RG: Insulin-like growth factor (IGF)-independent action of IGF-binding protein-3 in Hs578T human breast cancer cells: cell surface binding and growth inhibition. J Biol Chem 268: 14964-14971, 1993
12. Chen JC, Shao ZM, Sheikh MS, Hussain A, LeRoith D, Roberts CT Jr, Fontana JA: Insulin-like growth factor-binding protein enhancement of insulin-like growth faclor-I (IGF-1)-mediated DNA synthesis and IGF-1 binding in a human breast carcinoma cell line. J Cell Physiol 158: 69-78, 1994
13. Kim I, Manni A, Lynch J, Hammond JM: Identification and regulation of insulin-like growth factor binding proteins produced by hormone-dependent and -independent human breast cancer cell lines. Mol Cell Endocrinol 78: 71-78, 1991
14. Adamo ML, Shao ZM, Lanau F, Chen JC, Clemmons DR, Roberts CT Jr, LeRoith D, Fontana JA: Insulin-like growth faclor-I (IGF-I) and retinoic acid modulation of IGF-binding proteins (IGFBPs): IGFBP-2, -3, and -4 gene expression and protein secretion in a breast cancer cell line. Endocrinology 131: 1858-1866, 1992
15. Clemmons DR: IGF binding proteins and their functions. Mol Reprod Develop 35: 368-374, 1993
16. Conover CA, DeLeon DD: Acid-activated insulin-like growth factor-binding protein-3 proteolysis in normal and transformed cells: role of cathepsin D. J Biol Chem 269: 7076-7080, 1994
17. Baxter RC, Skriver L: Altered ligand specificity of proleolysed insulin-like growth factor binding protein-3. Biochem Biophys Res Commun 196: 1267-1273, 1993
18. Grimes RW, Hammond JM: Insulin and insulin-like growth factors (IGFs) stimulate production of IGF-binding proteins by ovarian granulosa cells. Endocrinology 131: 553-558, 1992
19. Grimes RW, Hammond JM: Proteolytic degradation of insulin-like growth factor (IGF)-hinding protein-3 by porcine ovarian granulosa cells in culture: regulation by IGF-I. Endocrinology 134: 337-343, 1994
20. Walton PE, Baxter RC, Burleigh BD, Etherton TD: Purification of the serum acid-stable insulin-like growth factor binding protein from the pig (Sus scrofa). Comp Biochem Physiol 92B: 561-567, 1989
21. Gill JL: Design and Analysis of Experiments in the Animal and Medical Sciences, vol. 1. Ames: Iowa State University Press, 1978
22. Figueroa JA, Yee D: The insulin-like growth factor binding proteins (IGFBPs) in human breast cancer. Breast Cancer Res Treat 22: 81-90, 1992
23. Rechler MM, Nisley SP: The nature and regulation of the receptors for insulin-like growth factors. Annu Rev Physiol 47: 425-442, 1985
24. Dong XF, Berthois Y, Martin PM: Effect of epidermal growth factor on the proliferation of human epithelial cancer cell lines: correlation with the level of occupied EGF receptor. Anticancer Res 11: 737-743, 1991
25. Smith EP, Lu L, Chernausek SD, Klein DJ: Insulin-like growth factor-binding protein-3 (IGFBP-3) concentration in rat Sertoli cell-conditioned medium is regulated by a pathway involving association of IGFBP-3 with cell surface proteoglycans. Endocrinology 135: 359-364, 1994
26. Martin JL, Ballesteros M, Baxter RC: Insulin-like growth factor-I (IGF-I) and transforming growth factor-beta 1 release IGF-binding protein-3 from human fibroblasts by different mechanisms. Endocrinology 131: 1703-1710, 1992
27. Ballard JF, Walton PE, Bastian S, Tomas FM, Wallace JC, Francis GL: Effects of interactions between IGFBPs and IGFs on the plasma clearance and in vivo biological activities of IGFs and IGF analogs. Growth Regul 3: 40-44, 1993
28. Oh Y, Muller HL, Pham H, Lamson G, Rosenfeld RJ: Insulin-like growth factor binding protein (IGFBP)-3 levels in conditioned media of Hs578T human breast cancer cells are post-transcriptionally regulated. Growth Regul 3: 84-87, 1993
29. Rochefort H, Capony F, Garcia M: Cathepsin D: a protease involved in breast cancer metastasis. Cancer Metastasis Rev 9: 321-331, 1990
30. Frost VJ, Macaulay VM, Wass JA, Holly JM: Proteolytic modification of insulin-like growth factor-binding proteins: comparison of conditioned media from human cell lines circulating proteases and characterized enzymes. J Endocrinol 138: 545-554, 1993
31. Oh Y, Muller HL, Pham H, Rosenfeld RG: Demonstration of receptors for insulin-like growth factor binding protein-3 on Hs578T human breast cancer cells. J Biol Chem 269: 26045-26048, 1993
32. Campbell PG, Novak JF, Wines K, Walton PE: Localization of plasmin activity on osteosarcoma cells: cell surface proteolysis of insulin-like growth factor binding proteins. Growth Regul 3: 95-98, 1993
33. Conover CA: Potentiation of insulin-like growth factor (IGF) action by IGF binding protein-3: studies of an underlying mechanism. Endocrinology 130: 3191-3200, 1992
34. Lamson G. Giudice LC, Cohen P, Liu F, Gargosky S, Muller H, Oh Y, Wilson KF, Hintz RL, Rosenfeld RG: Proteolysis of IGFBP-3 may be a common regulatory mechanism of IGF action in vivo. Growth Regul 3: 91-95, 1993