Phosphodiesterase 4 in macrophages: Relationship between cAMP accumulation, suppression of cAMP hydrolysis and inhibition of [3H]R-(-)-rolipram binding by selective inhibitors

Biochemical Journal

Volumn 318, Issue 2, 1996, Pages 425-436

  Kelly, John J ^a,b   Barnes, Peter J ^a   Giembycz, Mark A ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^b UNIVERSITY OF SOUTH ALABAMA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENAFENTRINE; CYCLIC AMP; ENZYME INHIBITOR; MEMBRANE ENZYME; NITRAQUAZONE; ORG 20241; PHOSPHODIESTERASE; ROLIPRAM; UNCLASSIFIED DRUG; VANADYL DERIVATIVE;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CHEMICAL REACTION KINETICS; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG HYDROLYSIS; DRUG POTENCY; DRUG PROTEIN BINDING; ENZYME CONFORMATION; ENZYME INHIBITION; ISOTOPE LABELING; MACROPHAGE; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; SMOOTH MUSCLE RELAXATION; STOMACH ACID SECRETION;

ANIMALIA; CAVIA PORCELLUS; SUS SCROFA;

EID: 0029831909     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/bj3180425     Document Type: Article

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