Mammillary body and cerebellar shrinkage in chronic alcoholics with and without amnesia

Alcoholism: Clinical and Experimental Research

Volumn 20, Issue 8, 1996, Pages 1489-1495

  Shear, Paula K ^a   Sullivan, Edith V ^a,b   Lane, Barton ^a,b   Pfefferbaum, Adolf ^a,b  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VA PALO ALTO HEALTH CARE SYSTEM   (United States)

Author keywords

Alcohol; Cerebellum; Imaging; Korsakoff; Mammillary Bodies

Indexed keywords

ADULT; ALCOHOLISM; AMNESIA; ARTICLE; BRAIN ATROPHY; CEREBELLUM; CHRONIC DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; KORSAKOFF PSYCHOSIS; MALE; MAMMILLARY BODY; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL;

EID: 0029831564     PISSN: 01456008     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1530-0277.1996.tb01153.x     Document Type: Article

References (52)

1. Ron MA, Acker RW, Shaw GK, Lishman WA: Computerized tomography of the brain in chronic alcoholism: A survey and follow-up study. Brain 105:497-514, 1982
2. Jernigan TL, Zatz LM, Ahumada AJ, Pfefferbaum A, Tinklenberg JR, Moses JA: CT measures of cerebrospinal fluid volume in alcoholics and normal volunteers. Psychiatry Res 7:9-17, 1982
3. Jernigan TL, Butters N, DiTraglia G, Schafer K, Smith T, Irwin M, Grant I, Schuckit M, Cermak LS: Reduced cerebral grey matter observed in alcoholics using magnetic resonance imaging. Alcohol Clin Exp Res 15:418-427, 1991
4. Pfefferbaum A, Rosenbloom MJ, Crusan K, Jernigan TL: Brain CT changes in alcoholics. The effects of age and alcohol consumption. Alcohol Clin Exp Res 12:81-87, 1988
5. Pfefferbaum A, Lim KO, Zipursky RB, Mathalon DH, Rosenbloom MJ, Lane B, Ha CN, Sullivan EV: Brain gray and white matter volume loss accelerates with aging in chronic alcoholics: A quantitative MRI study. Alcohol Clin Exp Res 16:1078-1089, 1992
6. Carlen PL, Wortzman G, Holgate RC, Wilkinson DA, Rankin JC: Reversible cerebral atrophy in recently abstinent chronic alcoholics measured by computed tomography scans. Science 200:1076-1078, 1978
7. Zipursky RB, Lim KO, Pfefferbaum A: MRI study of brain changes with short term abstinence from alcohol. Alcohol Clin Exp Res 13:664-666, 1989
8. Shear PK, Jernigan TL, Butters N: Volumetric magnetic resonance imaging quantification of longitudinal brain changes in abstinent alcoholics. Alcohol Clin Exp Res 18:172-176, 1994
9. Pfefferbaum A, Sullivan EV, Mathalon DH, Shear PK, Rosenbloom MJ, Lim KO: Longitudinal changes in MRI brain volumes in abstinent and relapsed alcoholics. Alcohol din Exp Res 19:1177-1191, 1995
10. Torvik A, Lindboe CF, Rodge S: Brain lesions in alcoholics: A neuropathological study with clinical correlations. J Neurol Sci 56:233-248, 1982
11. Victor M, Adams RD, Collins GH: The Wernicke-Korsakoff Syndrome and Related Neurologic Disorders Due to Alcoholism and Malnutrition, ed 2. Philadelphia: F.A. Davis Co, 1989
12. Arendt T, Bigl V, Arendt A, Tennstedt A: Loss of neurons in the nucleus basalis of Meynert in Alzheimer's disease, paralysis agitans, and Korsakoff's disease. Acta Neuropathol 61:101-108, 1983
13. Shimamura AP, Jernigan TL, Squire LR: Korsakoff's syndrome: Radiological (CT) findings and neuropsychological correlates. J Neurosci 8:4400-4410, 1988
14. Squire LR, Amaral DG, Press GA: Magnetic resonance Imaging of the hippocampal formation and mammillary nuclei distinguish medial temporal lobe and diencephalic amnesia. J Neurosci 10:3106-3117, 1990
15. Charness ME, DeLaPaz RL: Mammillary body atrophy in Wernicke's encephalopathy: Antemortem identification using magnetic resonance imaging. Ann Neurol 22:595-600, 1987
16. Charness ME: Brain lesions in alcoholics. Alcohol Clin Exp Res 17:2-11, 1993
17. Harper C: Wernicke's encephalopathy: A more common disease than realized, A neuropathological study of 51 cases. J Neurol Neurosurg Psychiatry 42:226-232, 1979
18. Harper CG: The incidence of Wernicke's encephalopathy in Australia: A neuropathological study of 131 cases. J Neurol Neurosurg Psychiatry 46:593-598, 1983
19. Harper CG, Kril JJ: Neuropathology of alcoholism. Alcohol Alcohol 25:207-216, 1990
20. Torvik A: Wernicke's encephalopathy: Prevalence and clinical spectrum. Alcohol Alcohol (Suppl. 1):381-384, 1991
21. Torvik A, Torp S: The prevalence of alcoholic cerebellar atrophy: A morphometric and histological study of an autopsy material. J Neurol Sci 75:43-51, 1986
22. Carlen PL, Penn RD, Fornazzari L, Bennett J, Wilkinson DA, Wortzman G: Computerized tomographic scan assessment of alcoholic brain damage and its potential reversibility. Alcohol Clin Exp Res 10:226-232, 1986
23. Haubek A, Lee K: Computed tomography in alcoholic cerebellar atrophy. Neuroradiology 18:77-79, 1979
24. Hillbom M, Muuronen A, Holme L, Hindmarsh T: The clinical versus radiological diagnosis of alcoholic cerebellar degeneration. J Neurol Sci 73:45-53, 1986
25. Blansjaar B, Van Dijk J: Korsakoff minus Wernicke syndrome. Alcohol Alcohol 27:435-437, 1992
26. Davila MD, Shear PK, Lane B, Sullivan EV Pfefferbaum A: Mammillary body and cerebellar shrinkage in chronic alcoholics: An MRI and neuropsychological study. Neuropsychology 8:433-444, 1994
27. Sullivan EV, Deshmukh A, Desmond JE, Lane, B Jr., Lane B, Shear AK, Pfefferbaum A: Volumetric MRI analysis of cerebellar hemispheres and vermis in chronic alcoholics: Relationship to ataxia. J Int Neuropsychol Soc 2:34, 1996 (abstr)
28. Blansjaar B, Vielvoye G, van Dijk J, Rijnders R: Similar brain lesions in alcoholics and Korsakoff patients: MRI, psychometric and clinical findings. Clin Neurol Neurosurg 93:197-203, 1992
29. Raz N, Torres IJ, Acker JD: Age-related shrinkage of the mammillary bodies: In vivo MRI evidence. NeuroReport 3:713-716, 1992
30. Shear PK, Sullivan EV, Davila MD, Lane, B., Pfefferbaum, A: Correlates of mammillary body and cerebellar abnormalities in chronic, nonamnesic alcoholics. 22nd Annual Meeting of the International Neuropsychological Society: Program and Abstracts 109, 1994 (abstr)
31. Sullivan EV, Marsh L, Mathalon DH, Lim KO, Pfefferbaum A: Age-related decline in MRI volumes of temporal lobe gray matter but not hippocampus. Neurobiol Aging 16:591-606, 1995
32. Pfefferbaum A, Mathalon DH, Sullivan EV, Rawles JM, Zipursky RB, Lim KO: A quantitative magnetic resonance imaging study of changes in brain morphology from infancy to late adulthood. Arch Neurol 51:874-887, 1994
33. Endicott J, Spitzer RL: A diagnostic interview: The Schedule for Affective Disorders and Schizophrenia. Arch Gen Psychiatry 35:837-844, 1978
34. Spitzer RL, Endicott J, Robins E: Research Diagnostic Criteria (RDC). New York, Biometrics Research, New York State Psychiatric Institute, 1975
35. Pfefferbaum A, Sullivan EV, Rosenbloom MJ, Shear PK, Mathalon DH, Lim KO: Increase in brain CSF volume is greater in older than younger alcoholics: A replication study and CT/MRI comparison. Psychiatry Res 50:257-274, 1993
36. Pfefferbaum A, Lim KO, Desmond J, Sullivan EV: Thinning of the corpus callosum in older alcoholic men: A magnetic resonance imaging study. Alcohol Clin Exp Res 20:752-757, 1996
37. Sullivan EV, Marsh L, Mathalon DH, Lim KO, Pfefferbaum A: Anterior hippocampal volume deficits in nonamnesic, aging chronic alcoholics. Alcohol Clin Exp Res 19:110-122, 1995
38. American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorder (DSM-IV). Washington, DC, American Psychiatric Association, 1994
39. Wechsler D: Manual for the Wechsler Adult Intelligence Scale Revised. New York, The Psychological Corporation, 1981
40. Nelson HE: The National Adult Reading Scale (NART). Windsor, Nelson Publishing Company, 1982
41. Wechsler D: Wechsler Memory Scale - Revised. San Antonio, TX, The Psychological Corporation, 1987
42. Oscar-Berman M, Clancy JP, Weber DA: Discrepancies between IQ and memory scores in alcoholism and aging. Clin Neuropsychol 7:281-296, 1993
43. Weiskrantz L: On issues and theories of the human amnesic syndrome, in McGaugh JL, Lynch G (eds): Memory Systems of the Brain. New York, Guilford Press, 1985, pp 380-415
44. Crovitz HF, Zener KA: Group test for assessing hand and eye dominance. Am J Psychol 75:271-276, 1962
45. Lim KO, Zipursky RB, Murphy GM, Pfefferbaum A: In vivo quantification of the limbic system using MRI: Effects of normal aging. Psychiatry Res: Neuroimaging 35:15-26, 1990
46. Lim KO, Pfefferbaum A: Segmentation of MR brain images into cerebrospinal fluid spaces, white and gray matter. J Comput Assist Tomogr 13:588-593, 1989
47. Bigler ED, Nelson JE, Schmidt RD: Mammillary body atrophy identified by magnetic resonance imaging in alcohol amnestic (Korsakoffs) syndrome. Neuropsychiatr Neuropsychol Behav Neurol 2:189-201, 1989
48. Bullmore E, Brammer M, Harvey I, Ron M: Against the laterality index as a measure of cerebral asymmetry. Psychiatry Res: Neuroimaging 61:121-124, 1995
49. Welch LW, Nimmerrichter A, Kessler RK, King D, Hoehn R, Margolin R, Martin PR: Severe global amnesia presenting as Wernicke-Korsakoff syndrome but resulting from atypical lesions. Psychol Med 26:421-425, 1996
50. Butters N, Stuss DT: Diencephalic amnesia, in Boller F, Grafman J (eds): Handbook of Neuropsychology, vol 3. Amsterdam, Elsevier, 1989, pp 107-148
51. Squire LR: Comparisons between forms of amnesia: Some deficits are unique to Korsakoff's Syndrome. J Exp Psychol Learn Mem Cog 8:560-571, 1982
52. Jernigan TL, Schafer K, Butters N, Cermak LS: Magnetic resonance imaging of alcoholic Korsakoff patients. Neuropsychopharmacology 4:175-186, 1991