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Volumn 13, Issue 8, 1996, Pages 417-437

Effects of methylprednisolone on lesioned and uninjured mammalian spinal neurons: Viability, ultrastructure, and network electrophysiology

Author keywords

methylprednisolone; neuronal network activity; neuronal survival; spinal cord; toxicity; trauma; ultrastructure

Indexed keywords

4 AMINOBUTYRIC ACID; METHYLPREDNISOLONE SODIUM SUCCINATE; N METHYL DEXTRO ASPARTIC ACID;

EID: 0029831333     PISSN: 08977151     EISSN: None     Source Type: Journal    
DOI: 10.1089/neu.1996.13.417     Document Type: Article
Times cited : (6)

References (65)
  • 1
    • 0022396301 scopus 로고
    • Iron-induced lipid peroxidation in spinal cord: Protection with mannitol and methylprednisolone
    • ANDERSON, D.K., ANDERSON, D.K., and MEANS, E.D. (1985). Iron-induced lipid peroxidation in spinal cord: Protection with mannitol and methylprednisolone. J. Free Radical Biol. Med. 1, 59-64.
    • (1985) J. Free Radical Biol. Med. , vol.1 , pp. 59-64
    • Anderson, D.K.1    Anderson, D.K.2    Means, E.D.3
  • 3
    • 0028088848 scopus 로고
    • Methylprednisolone and membrane properties of primary cultures of mouse spinal cord
    • ANDERSON, D.K., DUGAN, L.L., MEANS, E.D., and HORROCKS, L.A. (1994). Methylprednisolone and membrane properties of primary cultures of mouse spinal cord. Brain Res. 637, 119-125.
    • (1994) Brain Res. , vol.637 , pp. 119-125
    • Anderson, D.K.1    Dugan, L.L.2    Means, E.D.3    Horrocks, L.A.4
  • 4
    • 0018132354 scopus 로고
    • Pathology of experimental spinal cord trauma. II. Ultrastructure of axons and myelin
    • BALENTINE, J.D. (1978). Pathology of experimental spinal cord trauma. II. Ultrastructure of axons and myelin. Lab. Invest. 39, 254-266.
    • (1978) Lab. Invest. , vol.39 , pp. 254-266
    • Balentine, J.D.1
  • 5
    • 0023625506 scopus 로고
    • The multimolecular cascade of spinal cord injury: Studies on prostanoids, calcium and proteinases
    • BANIK, N.L., HOGAN, E.L., and HSU, C.Y. (1987). The multimolecular cascade of spinal cord injury: Studies on prostanoids, calcium and proteinases. Neurochem. Pathol. 7, 57-77.
    • (1987) Neurochem. Pathol. , vol.7 , pp. 57-77
    • Banik, N.L.1    Hogan, E.L.2    Hsu, C.Y.3
  • 6
    • 0020583141 scopus 로고
    • Inhibition of phospholipase
    • BLACKWELL, G.J., and FLOWER, R.J. (1983). Inhibition of phospholipase. Br. Med. Bull. 39, 260-264.
    • (1983) Br. Med. Bull. , vol.39 , pp. 260-264
    • Blackwell, G.J.1    Flower, R.J.2
  • 7
    • 0018849841 scopus 로고
    • Large and persistent electrical currents enter the transected lamprey spinal cord
    • BORGENS, R.B., JOFFE, L.F., and COHEN, M.J. (1980). Large and persistent electrical currents enter the transected lamprey spinal cord. Proc. Natl. Acad. Sci. U.S.A. 77, 1209-1213.
    • (1980) Proc. Natl. Acad. Sci. U.S.A. , vol.77 , pp. 1209-1213
    • Borgens, R.B.1    Joffe, L.F.2    Cohen, M.J.3
  • 8
    • 0025344617 scopus 로고
    • A randomized, controlled trial of methylprednisolone or naloxone in the treatment of acute spinal-cord injury
    • BRACKEN, M.B., SHEPARD, M.J., COLLINS, W.F., et al. (1990). A randomized, controlled trial of methylprednisolone or naloxone in the treatment of acute spinal-cord injury. N. Engl. J. Med. 322, 1405-1411.
    • (1990) N. Engl. J. Med. , vol.322 , pp. 1405-1411
    • Bracken, M.B.1    Shepard, M.J.2    Collins, W.F.3
  • 9
    • 2642692810 scopus 로고
    • Methylprednisolone or naloxone treatment after acute spinal cord injury: 1-year follow-up data
    • BRACKEN, M.B., SHEPARD, M.J., COLLINS, W.F., et al. (1992). Methylprednisolone or naloxone treatment after acute spinal cord injury: 1-year follow-up data. J. Neurosurg. 58, 538-542.
    • (1992) J. Neurosurg. , vol.58 , pp. 538-542
    • Bracken, M.B.1    Shepard, M.J.2    Collins, W.F.3
  • 10
    • 0019510430 scopus 로고
    • +)-ATPase activity in cats following intravenous methylprednisolone
    • +)-ATPase activity in cats following intravenous methylprednisolone. Brain Res. 219, 464-469.
    • (1981) Brain Res. , vol.219 , pp. 464-469
    • Braughler, J.M.1    Hall, E.D.2
  • 11
    • 0019996279 scopus 로고
    • +)-ATPase, lipid peroxidation, and alpha motor neuron function
    • +)-ATPase, lipid peroxidation, and alpha motor neuron function. J. Neurosurg. 56, 838-844.
    • (1982) J. Neurosurg. , vol.56 , pp. 838-844
    • Braughler, J.M.1    Hall, E.D.2
  • 12
    • 0020623237 scopus 로고
    • Uptake and elimination of methylprednisolone from contused cat spinal cord following intravenous injection of the sodium succinate ester
    • BRAUGHLER, J.M., and HALL, E.D. (1983a). Uptake and elimination of methylprednisolone from contused cat spinal cord following intravenous injection of the sodium succinate ester. J. Neurosurg. 58, 538-542.
    • (1983) J. Neurosurg. , vol.58 , pp. 538-542
    • Braughler, J.M.1    Hall, E.D.2
  • 13
    • 0020612791 scopus 로고
    • Lactate and pyruvate metabolism in injured cat spinal cord before and after a single large dose of methylprednisolone
    • BRAUGHLER, J.M., and HALL, E.D. (1983b). Lactate and pyruvate metabolism in injured cat spinal cord before and after a single large dose of methylprednisolone. J. Neurosurg. 59, 256-261.
    • (1983) J. Neurosurg. , vol.59 , pp. 256-261
    • Braughler, J.M.1    Hall, E.D.2
  • 14
    • 0021255932 scopus 로고
    • Effects of multidose methylprednisolone sodium succinate administration on injured cat spinal cord neurofilament degradation and energy metabolism
    • BRAUGHLER, J.M., and HALL, E.D. (1984). Effects of multidose methylprednisolone sodium succinate administration on injured cat spinal cord neurofilament degradation and energy metabolism. J. Neurosurg. 61, 290-295.
    • (1984) J. Neurosurg. , vol.61 , pp. 290-295
    • Braughler, J.M.1    Hall, E.D.2
  • 15
    • 0017852099 scopus 로고
    • An electron microscopic analysis of axonal alterations following blunt contusion of the spinal cord of the rhesus monkey (Macaca mulatta)
    • BRESNAHAN, J.C. (1978). An electron microscopic analysis of axonal alterations following blunt contusion of the spinal cord of the rhesus monkey (Macaca mulatta). J. Neurol. Sci. 37, 59-82.
    • (1978) J. Neurol. Sci. , vol.37 , pp. 59-82
    • Bresnahan, J.C.1
  • 16
    • 0017169750 scopus 로고
    • A neuroanatomical analysis of spinal cord injury in the rhesus monkey (Macaca mulatta)
    • BRESNAHAN, J.C., KING, J.S., MARTIN, G.F., and YASHON, D. (1976). A neuroanatomical analysis of spinal cord injury in the rhesus monkey (Macaca mulatta). J. Neurological Sci. 28, 521-542.
    • (1976) J. Neurological Sci. , vol.28 , pp. 521-542
    • Bresnahan, J.C.1    King, J.S.2    Martin, G.F.3    Yashon, D.4
  • 17
    • 0015389468 scopus 로고
    • The effect of massive pulse steroid therapy on the water content of the rat brain
    • CERILLI, J., and MILLER, J.A. (1972). The effect of massive pulse steroid therapy on the water content of the rat brain. Transplantation 14, 403-405.
    • (1972) Transplantation , vol.14 , pp. 403-405
    • Cerilli, J.1    Miller, J.A.2
  • 18
    • 9544255240 scopus 로고
    • Arachidonic acid metabolites and membrane lipid changes in central nervous system injury
    • D.G. Stein and B.A. Sabels (eds), Plenum, NY
    • DEMEDIUK, P., and FADEN, A.I. (1988). Arachidonic acid metabolites and membrane lipid changes in central nervous system injury, in: Pharmacological Approaches to the Treatment of Brain and Spinal Cord Injury. D.G. Stein and B.A. Sabels (eds), Plenum, NY, pp. 23-42.
    • (1988) Pharmacological Approaches to the Treatment of Brain and Spinal Cord Injury , pp. 23-42
    • Demediuk, P.1    Faden, A.I.2
  • 19
    • 0020464082 scopus 로고
    • Further studies on free radical pathology in the major nervous system disorders: Effect of very high doses of methylprednisolone on the functional outcome, morphology and chemistry of experimental spinal cord impact injury
    • DEMOPOULOS, H.B., FLAMM, E.S., SELIGMAN, M.L., PIETRONIGRO, D.D., TOMASULA, J., and DECRESCITO, V. (1982). Further studies on free radical pathology in the major nervous system disorders: Effect of very high doses of methylprednisolone on the functional outcome, morphology and chemistry of experimental spinal cord impact injury. Can. J. Physiol. Pharmacol. 60, 1416-1424.
    • (1982) Can. J. Physiol. Pharmacol. , vol.60 , pp. 1416-1424
    • Demopoulos, H.B.1    Flamm, E.S.2    Seligman, M.L.3    Pietronigro, D.D.4    Tomasula, J.5    Decrescito, V.6
  • 21
    • 0023237381 scopus 로고
    • The sequence of ultrastructural changes in cultured neurons after dendrite transection
    • EMERY, D.G., LUCAS, J.H., and GROSS, G.W. (1987). The sequence of ultrastructural changes in cultured neurons after dendrite transection. Exp. Brain Res. 67, 41-51.
    • (1987) Exp. Brain Res. , vol.67 , pp. 41-51
    • Emery, D.G.1    Lucas, J.H.2    Gross, G.W.3
  • 22
    • 0025882688 scopus 로고
    • Contributions of sodium and chloride to ultrastructural damage after dendrotomy
    • EMERY, D.G., LUCAS, J.H., and GROSS, G.W. (1991). Contributions of sodium and chloride to ultrastructural damage after dendrotomy. Exp. Brain Res. 86, 60-72.
    • (1991) Exp. Brain Res. , vol.86 , pp. 60-72
    • Emery, D.G.1    Lucas, J.H.2    Gross, G.W.3
  • 23
    • 9544232079 scopus 로고
    • Reduction of NaCl ameliorates ultrastructural damage to dendrotomized mammalian spinal neurons
    • EMERY, D.G., ROSENBERG, L.J., and LUCAS. J.H. (1995). Reduction of NaCl ameliorates ultrastructural damage to dendrotomized mammalian spinal neurons. Soc. Neurosci. Abstr. 21, 2118.
    • (1995) Soc. Neurosci. Abstr. , vol.21 , pp. 2118
    • Emery, D.G.1    Rosenberg, L.J.2    Lucas, J.H.3
  • 24
    • 0029996583 scopus 로고    scopus 로고
    • Effects of methylprednisolone on the GABA- and glutamate-induced currents: Relevance to glucoconicoid-induced neurotoxicity and brain aging
    • FOROUTAN, A., BEHBEHANI, M.M., and ANDERSON, D.K. (1996). Effects of methylprednisolone on the GABA- and glutamate-induced currents: Relevance to glucoconicoid-induced neurotoxicity and brain aging. Steroids 61, 354-366.
    • (1996) Steroids , vol.61 , pp. 354-366
    • Foroutan, A.1    Behbehani, M.M.2    Anderson, D.K.3
  • 25
    • 0018331316 scopus 로고
    • Simultaneous single unit recording in vitro with a photoetched laser deinsulated gold multimicroelectrode surface
    • GROSS, G.W. (1979). Simultaneous single unit recording in vitro with a photoetched laser deinsulated gold multimicroelectrode surface. IEEE Trans. Biomend. Eng. 26, 273-279.
    • (1979) IEEE Trans. Biomend. Eng. , vol.26 , pp. 273-279
    • Gross, G.W.1
  • 26
    • 0023254869 scopus 로고
    • Cytoplasmic damage gradients in dendrites after transection lesions
    • GROSS, G.W., and HIGGINS, M.L. (1987). Cytoplasmic damage gradients in dendrites after transection lesions. Exp. Brain Res. 67, 52-60.
    • (1987) Exp. Brain Res. , vol.67 , pp. 52-60
    • Gross, G.W.1    Higgins, M.L.2
  • 27
    • 0021086682 scopus 로고
    • Laser microbeam surgery: Ultrastructural changes associated with neunte transection in culture
    • GROSS, G.W., LUCAS, J.H., and HIGGINS, M.L. (1983). Laser microbeam surgery: Ultrastructural changes associated with neunte transection in culture. J. Neurosci. 3, 1979-1993.
    • (1983) J. Neurosci. , vol.3 , pp. 1979-1993
    • Gross, G.W.1    Lucas, J.H.2    Higgins, M.L.3
  • 28
    • 0022367558 scopus 로고
    • Transparent indium-tin oxide patterns for extracellular multisite recording in neuronal cultures
    • GROSS, G.W., WEN, W., and LIN, J. (1985). Transparent indium-tin oxide patterns for extracellular multisite recording in neuronal cultures. J. Neurosci. Methods 15, 243-252.
    • (1985) J. Neurosci. Methods , vol.15 , pp. 243-252
    • Gross, G.W.1    Wen, W.2    Lin, J.3
  • 29
    • 0020014110 scopus 로고
    • Glucocorticoid effects on central nervous excitability and synaptic transmission
    • HALL, E.D. (1982). Glucocorticoid effects on central nervous excitability and synaptic transmission. Int. Rev. Neurobiol. 23, 165-195.
    • (1982) Int. Rev. Neurobiol. , vol.23 , pp. 165-195
    • Hall, E.D.1
  • 30
    • 17044451389 scopus 로고
    • Inhibition of lipid peroxidation in CNS trauma
    • HALL, E.D. (1991). Inhibition of lipid peroxidation in CNS trauma. J. Neurotrauma 8, S31-S41.
    • (1991) J. Neurotrauma , vol.8
    • Hall, E.D.1
  • 31
    • 0027365090 scopus 로고
    • Neuroprotective actions of glucocorticoid and nonglucocorticoid steroids in acute neuronal injury
    • HALL, E.D. (1993). Neuroprotective actions of glucocorticoid and nonglucocorticoid steroids in acute neuronal injury. Cell. Mol. Neurobiol. 13, 415-432.
    • (1993) Cell. Mol. Neurobiol. , vol.13 , pp. 415-432
    • Hall, E.D.1
  • 32
    • 0019418759 scopus 로고
    • Acute effects of intravenous glucocorticoid pretreatment on the in vitro peroxidation of cat spinal cord tissue
    • HALL, E.D., and BRAUGHLER, J.M. (1981). Acute effects of intravenous glucocorticoid pretreatment on the in vitro peroxidation of cat spinal cord tissue. Exp. Neural. 73, 321-324.
    • (1981) Exp. Neural. , vol.73 , pp. 321-324
    • Hall, E.D.1    Braughler, J.M.2
  • 33
    • 0020048289 scopus 로고
    • +)-ATPase activity: Dose-response analysis during the first hour after contusion injury in the cat
    • +)-ATPase activity: Dose-response analysis during the first hour after contusion injury in the cat. J. Neurosurg. 57, 247-253.
    • (1982) J. Neurosurg. , vol.57 , pp. 247-253
    • Hall, E.D.1    Braughler, J.M.2
  • 34
    • 0022527394 scopus 로고
    • A pharmacological analysis of the pathophysiological mechanisms of post-traumatic spinal cord ischemia
    • HALL, E.D., and WOLF, D.L. (1986). A pharmacological analysis of the pathophysiological mechanisms of post-traumatic spinal cord ischemia. J. Neurosurg. 64, 951-961.
    • (1986) J. Neurosurg. , vol.64 , pp. 951-961
    • Hall, E.D.1    Wolf, D.L.2
  • 35
    • 0021267414 scopus 로고
    • Effects of a single large dose of methylprednisolone sodium succinate on experimental posttraumatic spinal cord ischemia: Dose-response and time-action analysis
    • HALL, E.D., WOLF, D.L., and BRAUGHLER, J.M. (1984). Effects of a single large dose of methylprednisolone sodium succinate on experimental posttraumatic spinal cord ischemia: Dose-response and time-action analysis. J. Neurosurg. 61, 124-130.
    • (1984) J. Neurosurg. , vol.61 , pp. 124-130
    • Hall, E.D.1    Wolf, D.L.2    Braughler, J.M.3
  • 36
    • 0023752162 scopus 로고
    • New pharmacological treatment of acute spinal cord trauma
    • HALL, E.D., BRAUGHLER, J.M., and MCCALL, J.M. (1988). New pharmacological treatment of acute spinal cord trauma. J. Neurotrauma 5, 81-89.
    • (1988) J. Neurotrauma , vol.5 , pp. 81-89
    • Hall, E.D.1    Braughler, J.M.2    Mccall, J.M.3
  • 37
    • 0023786642 scopus 로고
    • Analysis of methylprednisolone, methylprednisone and corticosterone for assessment of methylprednisolone disposition in the rat
    • HAUGHEY, D.B., and JUSKO, W.J. (1988). Analysis of methylprednisolone, methylprednisone and corticosterone for assessment of methylprednisolone disposition in the rat. J. Chromatogr. 430, 241-248.
    • (1988) J. Chromatogr. , vol.430 , pp. 241-248
    • Haughey, D.B.1    Jusko, W.J.2
  • 38
    • 0025032726 scopus 로고
    • Effect of methylprednisolone on motor function and spinal cord flow after spinal cord compression in rats
    • HOLTZ, A., NYSTROM, B., and GERDIN, B. (1990). Effect of methylprednisolone on motor function and spinal cord flow after spinal cord compression in rats. Acta Neurolog. Scand. 82, 68-73.
    • (1990) Acta Neurolog. Scand. , vol.82 , pp. 68-73
    • Holtz, A.1    Nystrom, B.2    Gerdin, B.3
  • 39
    • 0027180483 scopus 로고
    • Methylprednisolone treatment of experimental spinal cord injury
    • IWAI, A., MONAFO, W.W., and ELIASSON, S.G. (1993). Methylprednisolone treatment of experimental spinal cord injury. Paraplegia 31, 417-429.
    • (1993) Paraplegia , vol.31 , pp. 417-429
    • Iwai, A.1    Monafo, W.W.2    Eliasson, S.G.3
  • 40
    • 0027285503 scopus 로고
    • Methylprednisolone reduces excitatory amino acid release following experimental spinal cord injury
    • LIU, D., and MCADOO, DJ. (1993). Methylprednisolone reduces excitatory amino acid release following experimental spinal cord injury. Brain Res. 609, 293-297.
    • (1993) Brain Res. , vol.609 , pp. 293-297
    • Liu, D.1    Mcadoo, D.J.2
  • 41
    • 0023579171 scopus 로고
    • Proximal segment retraction increases the probability of nerve cell survival after dendrite transection
    • LUCAS, J.H. (1987). Proximal segment retraction increases the probability of nerve cell survival after dendrite transection. Brain Res. 425, 384-387.
    • (1987) Brain Res. , vol.425 , pp. 384-387
    • Lucas, J.H.1
  • 42
    • 0022189602 scopus 로고
    • Neuronal survival or death after dendrite transection close to the perikaryon: Correlation with electrophysiologic, morphologic and ultrastructural changes
    • LUCAS, J.H., GROSS, G.W., EMERY, D.G., and GARDNER, C.R. (1985). Neuronal survival or death after dendrite transection close to the perikaryon: Correlation with electrophysiologic, morphologic and ultrastructural changes. J. Neurotrauma (formerly Central Nervous System Trauma) 2, 231-255.
    • (1985) J. Neurotrauma (Formerly Central Nervous System Trauma) , vol.2 , pp. 231-255
    • Lucas, J.H.1    Gross, G.W.2    Emery, D.G.3    Gardner, C.R.4
  • 43
    • 0022622033 scopus 로고
    • Adhesion of cultured mammalian central nervous system neurons to flame-modified hydrophobic surfaces
    • LUCAS, J.H., CZISNY, L.E., and GROSS, G.W. (1986). Adhesion of cultured mammalian central nervous system neurons to flame-modified hydrophobic surfaces. In Vitro 22, 37-43.
    • (1986) In Vitro , vol.22 , pp. 37-43
    • Lucas, J.H.1    Czisny, L.E.2    Gross, G.W.3
  • 44
    • 0025151935 scopus 로고
    • Neuronal survival and dynamics of ultrastructural damage after dendrotomy in low calcium
    • LUCAS, J.H., EMERY, D.G., HIGGINS, M.L., and GROSS, G.W. (1990). Neuronal survival and dynamics of ultrastructural damage after dendrotomy in low calcium. J. Neurotrauma 7, 169-192.
    • (1990) J. Neurotrauma , vol.7 , pp. 169-192
    • Lucas, J.H.1    Emery, D.G.2    Higgins, M.L.3    Gross, G.W.4
  • 45
    • 9544241719 scopus 로고
    • Reduction of NaCl increases survival of mammalian spinal cord neurons after neunte transection injury
    • LUCAS, J.H., and ROSENBERG-SCHAFFER, L.J. (1994). Reduction of NaCl increases survival of mammalian spinal cord neurons after neunte transection injury. Soc. Neurosci. Abst. 20, 844.
    • (1994) Soc. Neurosci. Abst. , vol.20 , pp. 844
    • Lucas, J.H.1    Rosenberg-Schaffer, L.J.2
  • 46
    • 0000626258 scopus 로고
    • Tissue culture studies of neuronal responses to physical lesions of the plasma membrane: Environmental influences and experimental interventions
    • S.T. Ohnishi and T. Ohnishi (eds), Taylor and Francis, NY
    • LUCAS, J.H., EMERY, D.G., and GROSS, G.W. (1995). Tissue culture studies of neuronal responses to physical lesions of the plasma membrane: Environmental influences and experimental interventions, in: Membrane-Linked Diseases Vol. 4. S.T. Ohnishi and T. Ohnishi (eds), Taylor and Francis, NY, pp. 353-373.
    • (1995) Membrane-Linked Diseases , vol.4 , pp. 353-373
    • Lucas, J.H.1    Emery, D.G.2    Gross, G.W.3
  • 47
    • 0019414705 scopus 로고
    • Membrane conductance and action potentials of a regenerating axonal tip
    • MEIRI, H., SPIRA, M.E., and PARNAS, I. (1981). Membrane conductance and action potentials of a regenerating axonal tip. Science 211, 709-712.
    • (1981) Science , vol.211 , pp. 709-712
    • Meiri, H.1    Spira, M.E.2    Parnas, I.3
  • 48
    • 0019195324 scopus 로고
    • 2 as a further possible mechanisms of some actions of steroidal anti-inflammatory drugs
    • 2 as a further possible mechanisms of some actions of steroidal anti-inflammatory drugs. Pharm. Res. Commun. 12, 817-827.
    • (1980) Pharm. Res. Commun. , vol.12 , pp. 817-827
    • Mentz, P.1    Gieber, C.2    Forster, W.3
  • 50
    • 0002569886 scopus 로고
    • A three-dye test for cell viability
    • P.F. Kruse, Jr. and M.J. Patterson, Jr. (eds), Academic Press, NY
    • PHILLIPS, H.J. (1973). A three-dye test for cell viability, in: Tissue Culture, Methods and Applications. P.F. Kruse, Jr. and M.J. Patterson, Jr. (eds), Academic Press, NY, pp. 406-408.
    • (1973) Tissue Culture, Methods and Applications , pp. 406-408
    • Phillips, H.J.1
  • 51
    • 0017669602 scopus 로고
    • Mouse spinal cord in cell culture. I. Morphological and intrinsic electrophysiologic properties
    • RANSOM, B.R., NEALE, E., HENKHARY, M., BULLOCK, P.N., and NELSON, P.G. (1977). Mouse spinal cord in cell culture. I. Morphological and intrinsic electrophysiologic properties. J. Neurophysiol. 40, 1132-1150.
    • (1977) J. Neurophysiol. , vol.40 , pp. 1132-1150
    • Ransom, B.R.1    Neale, E.2    Henkhary, M.3    Bullock, P.N.4    Nelson, P.G.5
  • 52
    • 3042907682 scopus 로고
    • Reduction of extracellular Na+ increases survival of spinal cord neurons subjected to dendrotomy
    • ROSENBERG, L.J., EMERY, D.G., and LUCAS, J.H. (1995). Reduction of extracellular Na+ increases survival of spinal cord neurons subjected to dendrotomy. Soc. Neurosci. Abst. 21, 2118.
    • (1995) Soc. Neurosci. Abst. , vol.21 , pp. 2118
    • Rosenberg, L.J.1    Emery, D.G.2    Lucas, J.H.3
  • 53
    • 0027414339 scopus 로고
    • An in vitro study of the effects of methylprednisolone on lesioned and uninjured mammalian spinal neurons
    • ROSENBERG-SCHAFFER, L.J., and LUCAS, J.H. (1993). An in vitro study of the effects of methylprednisolone on lesioned and uninjured mammalian spinal neurons. Brain Res. 605, 327-331.
    • (1993) Brain Res. , vol.605 , pp. 327-331
    • Rosenberg-Schaffer, L.J.1    Lucas, J.H.2
  • 54
    • 0023195163 scopus 로고
    • Effects of methylprednisolone and the combination of alpha-tocopherol and selenium on arachidonic acid metabolism and lipid peroxidation in traumatized spinal cord tissue
    • SAUNDERS, R.D., DUGAN, L.L., DEMEDIUK, P., MEANS, E.D., HORROCKS, L.A., and ANDERSON, D.K. (1987). Effects of methylprednisolone and the combination of alpha-tocopherol and selenium on arachidonic acid metabolism and lipid peroxidation in traumatized spinal cord tissue. J. Neurochem. 49, 24-31.
    • (1987) J. Neurochem. , vol.49 , pp. 24-31
    • Saunders, R.D.1    Dugan, L.L.2    Demediuk, P.3    Means, E.D.4    Horrocks, L.A.5    Anderson, D.K.6
  • 55
    • 0018419001 scopus 로고
    • Corticosteroid (methylprednisolone) modulation of photoperoxidation by ultraviolet light in liposomes
    • SELIGMAN, M.L., MITAMURA, J., SHERA, N., and DEMOPOULOS, H.B. (1979). Corticosteroid (methylprednisolone) modulation of photoperoxidation by ultraviolet light in liposomes. Photochem. Photobiol. 29, 549-558.
    • (1979) Photochem. Photobiol. , vol.29 , pp. 549-558
    • Seligman, M.L.1    Mitamura, J.2    Shera, N.3    Demopoulos, H.B.4
  • 56
    • 0022421667 scopus 로고
    • High-performance liquid Chromatographic assay for methylprednisolone and its soluble prodrug esters in dog plasma
    • SHAW, J.A., and WEBER, D.J. (1985). High-performance liquid Chromatographic assay for methylprednisolone and its soluble prodrug esters in dog plasma. J. Chromatogr. 344, 41-49.
    • (1985) J. Chromatogr. , vol.344 , pp. 41-49
    • Shaw, J.A.1    Weber, D.J.2
  • 57
    • 0020622859 scopus 로고
    • Extracellular calcium activity in the injured spinal cord
    • STOKES, B.T., FOX, P., and HOLLINDEN, G. (1983). Extracellular calcium activity in the injured spinal cord. Exp. Neurol. 80, 561-572.
    • (1983) Exp. Neurol. , vol.80 , pp. 561-572
    • Stokes, B.T.1    Fox, P.2    Hollinden, G.3
  • 58
    • 0015882533 scopus 로고
    • Intravenous methylprednisolone sodium succinate: Adverse reactions reported in association with immunosuppressive therapy
    • STUBBS, S.S., and MORRELL, R.M. (1973). Intravenous methylprednisolone sodium succinate: Adverse reactions reported in association with immunosuppressive therapy. Transplant Proc. 5, 1145-1146.
    • (1973) Transplant Proc. , vol.5 , pp. 1145-1146
    • Stubbs, S.S.1    Morrell, R.M.2
  • 59
    • 0020662654 scopus 로고
    • Seizure after pulse therapy with methylprednisolone
    • SUCHMAN, A.L., CONDEMI, J.J., and LEDDY, J.P. (1983). Seizure after pulse therapy with methylprednisolone. Arthritis Rheum. 26, 117.
    • (1983) Arthritis Rheum. , vol.26 , pp. 117
    • Suchman, A.L.1    Condemi, J.J.2    Leddy, J.P.3
  • 61
    • 0027162954 scopus 로고
    • 2 activation and neuronal injury
    • 2 activation and neuronal injury. Ann. N.Y. Acad. Sci. 679, 110-120.
    • (1993) Ann. N.Y. Acad. Sci. , vol.679 , pp. 110-120
    • Verity, M.A.1
  • 62
    • 0019960776 scopus 로고
    • Effect of high dose corticosteroid therapy on blood flow, evoked potentials and extracellular calcium in experimental spinal cord injury
    • YOUNG, W., and FLAMM, E.S. (1982). Effect of high dose corticosteroid therapy on blood flow, evoked potentials and extracellular calcium in experimental spinal cord injury. J. Neurosurg. 57, 557-673.
    • (1982) J. Neurosurg. , vol.57 , pp. 557-673
    • Young, W.1    Flamm, E.S.2
  • 63
    • 0006372956 scopus 로고
    • Potassium and calcium changes in injured spinal cords
    • YOUNG, W., and KOREH, I. (1986). Potassium and calcium changes in injured spinal cords. Brain Res. 253, 189-253.
    • (1986) Brain Res. , vol.253 , pp. 189-253
    • Young, W.1    Koreh, I.2
  • 64
    • 0020361042 scopus 로고
    • Extracellular calcium ionic activity in experimental cord contusion
    • YOUNG, W., YEN, V., and BLIGHT, A. (1982). Extracellular calcium ionic activity in experimental cord contusion. Brain Res. 253, 105-113.
    • (1982) Brain Res. , vol.253 , pp. 105-113
    • Young, W.1    Yen, V.2    Blight, A.3
  • 65
    • 0023782824 scopus 로고
    • Pharmacological therapy of acute spinal cord injury: Studies of high-dose methyl-prednisolone and naloxone
    • YOUNG, W., DECRESCITO, V., FLAMM, E.S., BLIGHT, A.R., and GRUNER, J.A. (1988). Pharmacological therapy of acute spinal cord injury: Studies of high-dose methyl-prednisolone and naloxone. Clin. Neurosurg. 34, 675-697.
    • (1988) Clin. Neurosurg. , vol.34 , pp. 675-697
    • Young, W.1    Decrescito, V.2    Flamm, E.S.3    Blight, A.R.4    Gruner, J.A.5


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