Emotional and behavioral correlates of mediodorsal thalamic neurons during associative learning in rats

Journal of Neuroscience

Volumn 16, Issue 18, 1996, Pages 5812-5829

  Oyoshi, Tatsuki ^b   Nishijo, Hisao ^a   Asakura, Tetsuhiko ^b   Takamura, Yusaku ^a   Ono, Taketoshi ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

^b KAGOSHIMA UNIVERSITY   (Japan)

Author keywords

conditioning; emotionality; learning; mediodorsal thalamic nucleus; motor behavior; neuronal activity

Indexed keywords

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; AUDITORY STIMULATION; CONDITIONING; CONTROLLED STUDY; EMOTION; LIMBIC SYSTEM; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REWARD; STATE DEPENDENT LEARNING; THALAMUS NUCLEUS; VISUAL STIMULATION;

EID: 0029830912     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.16-18-05812.1996     Document Type: Article

References (74)

1. Aggleton JP, Mishkin M (1983) Visual recognition impairment following medial thalamic lesions in monkeys. Neuropsychologia 21:189-197.
2. Aggleton JP, Mishkin M (1984) Projection of the amygdala to the thalamus in the cynomolgus monkey. J Comp Neurol 222:56-68.
3. Andersen E (1986) Periaqueductal gray and cerebral cortex modulate responses of medial thalamic neurons to noxious stimulation. Brain Res 375:30-36.
4. Bachevalier J, Mishkin M (1986) Visual recognition impairment follows ventromedial but not dorsolateral prefrontal lesions in monkey. Behav Brain Res 20:249-261.
5. Butter CM, Snyder DR (1972) Alternations in aversive and aggressive behaviors following orbital frontal lesions in rhesus monkeys. Acta Neurobiol Exp 32:525-565.
6. Cassell MD, Wright DJ (1986) Topography of projections from the medial prefrontal cortex to the amygdala in the rat. Brain Res Bull 17:321-333.
7. Davidson TL, McKernan MG, Jarrard LE (1993) Hippocampal lesions do not impair negative patterning: a challenge to configural association theory. Behav Neurosci 107:227-234.
8. Davis M (1992) The role of the amygdala in conditioned fear. In: The amygdala: neurobiological aspects of emotion, memory, and mental dysfunction (Aggleton JP, ed), pp 255-305. New York: Wiley.
9. Davis M (1994) The role of the amygdala in emotional learning. Int Rev Neurobiol 36:225-266.
10. Drevets W (1995) PET and the functional anatomy of major depression. In: Emotion, memory and behavior (Nakajima T, Ono T, eds), pp 43-62. Tokyo: Japan Scientific.
11. Everitt BJ, Cador M, Robbins TW (1989) Interactions between the amygdala and ventral striatum in stimulus-reward associations: studies using second-order schedule of sexual reinforcement. Neuroscience 30:63-75.
12. Fahy FL, Riches IP, Brown MW (1993) Neuronal signals of importance to the performance of visual recognition memory task: evidence from recordings of single neurons in the medial thalamus of primates. Prog Brain Res 95:401-416.
13. Falls WA, Davis M (1995) Lesions of the central nucleus of the amygdala block conditioned excitation, but not conditioned inhibition of fear as measured with the fear-potentiated startle effect. Behav Neurosci 109:379-387.
14. Funahashi S, Bruce CJ, Goldman-Rakic PS (1990) Visuospatial coding in primate prefrontal neurons revealed by oculomotor paradigms. J Neurophysiol 63:814-831.
15. Funahashi S, Bruce CJ, Goldman-Rakic PS (1991) Neuronal activity related to saccadic eye movements in the monkey's dorsolateral prefrontal cortex. J Neurophysiol 65:1464-1483.
16. Fuster JM, Alexander GE (1973) Firing changes in cells of the nucleus medialis dorsalis associated with delayed response behavior. Brain Res 61:79-91.
17. Gaffan D, Harrison S (1987) Amygdalectomy and disconnection in visual learning for auditory secondary reinforcement by monkeys. J Neurosci 7:2285-2292.
18. Gaffan D, Harrison S (1991) Auditory-visual associations, hemispheric specialization and temporal-frontal interaction in the rhesus monkey. Brain 114:2133-2144.
19. Gaffan D, Murray EA (1990) Amygdalar interaction with the mediodorsal nucleus of the thalamus and the ventromedial prefrontal cortex in stimulus-reward associative learning in the monkey. J Neurosci 10:3479-3493.
20. Gaffan D, Murray EA, Fabre-Thorpe M (1993) Interaction of the amygdala with the frontal lobe in reward memory. Eur J Neurosci 5:968-975.
21. Goldman-Rakic PS, Porrino LJ (1985) The primate mediodorsal (MD) nucleus and its projection to the frontal lobe. J Comp Neurol 242:535-560.
22. Graff-Radford N, Damasio H, Yamada T, Eslinger PJ, Damasio AR (1985) Nonhemorrhagic thalamic infarction. Brain 108:485-516.
23. Groenewegen HJ (1988) Organization of the afferent connections of the mediodorsal thalamic nucleus in the rat, related to the mediodorsalprefrontal topography. Neuroscience 24:379-431.
24. Groenewegen HJ, Berendse HW, Wolters JG, Lohman AHM (1990) The anatomical relationship of the prefrontal cortex with the striatopallidal system, the thalamus and the amygdala: evidence for a parallel organization. Prog Brain Res 85:95-116.
25. Higuchi S, Zhou X, Konishi S, Hasegawa I, Miyashita Y (1995) Disruption of rhinal backward signals impairs visual associative coding of the inferotemporal neurons in monkeys. Soc Neurosci Abstr 47:10.
26. Hikosaka O, Wurtz RH (1983) Visual and oculomotor functions of monkey substantia nigra pars reticulata. III. Memory contingent visual and saccade response. J Neurophysiol 49:1268-1284.
27. Hikosaka O, Sakamoto M, Usui S (1989) Functional properties of monkey caudate neurons. I. Activities related to saccadic eye movements. J Neurophysiol 61:780-798.
28. Isseroff A, Rosvold HE, Galkin TW, Goldman-Rakic PS (1982) Spatial memory impairments following damage to the mediodorsal nucleus of the thalamus in rhesus monkeys. Brain Res 232:97-113.
29. Kim M, McGaugh JL (1992) Effects of intra-amygdala injections of NMDA receptor antagonists on acquisition and retention of inhibitory avoidance. Brain Res 585:35-48.
30. Krettek JE, Price JL (1977) The cortical projections of the mediodorsal nucleus and adjacent thalamic nuclei in the rat. J Comp Neurol 171:157-192.
31. Kurata K, Tanji J (1986) Premotor cortex neurons in macaques: activity before distal and proximal forelimb movements. J Neurosci 6:403-411.
32. Kubota K, Hamada I (1978) Visual tracking and neuron activity in the post-arcuate area in monkey. J Physiol (Paris) 74:297-313.
33. Kubota K, Niki H, Goto A (1972) Thalamic unit activity and delayed alternation performance in the monkey. Acta Neurobiol Exp 32:177-192.
34. Kubota Y, Gabriel M (1995) Studies of the limbic comparator: limbic circuit training-induced unit activity and avoidance behavior in rabbits with anterior dorsal thalamic lesions. Behav Neurosci 109:258-277.
35. Kuroda M, Price JL (1991a) Synaptic organization of projections from basal forebrain structures to the mediodorsal thalamic nucleus of the rat. J Comp Neurol 303:513-533.
36. Kuroda M, Price JL (1991b) Ultrastructure and synaptic organizations of axon terminals from brainstem structures to the mediodorsal thalamic nucleus of the rat. J Comp Neurol 313:539-552.
37. Lamarre Y, Busby L, Spidalieri G (1983) Fast ballistic arm movements triggered by visual, auditory, and somesthetic stimuli in the monkey. I. Activity of precentral cortical neurons. J Neurophysiol 50:1343-1358.
38. LeDoux JE (1987) Emotion. In: Handbook of physiology. I. The nervous system, Vol 5 (Mountcastle VB, ed), pp 419-459. Bethesda, MD: American Physiological Society.
39. Le Gros Clark WE (1932a) The structure and connections of the thalamus. Brain 55:406-470.
40. Le Gros Clark WE (1932b) An experimental study of thalamic connections in the rat. Philos Trans R Soc Lond [Biol] 221:1-28.
41. Leonard CM (1969) The prefrontal cortex of the rat. Brain Res 12:321-343.
42. Liles SL (1985) Activity of neurons in the putamen during active and passive movements of wrist. J Neurophysiol 53:217-236.
43. Markowitsch HJ (1982) Thalamic mediodorsal nucleus and memory: a critical evaluation of studies in animals and man. Neurosci Biobehav Rev 6:351-380.
44. Miserendino MJD, Sananes CB, Melia KR, Davis M (1990) Blocking of acquisition but not expression of conditioned fear-potentiated startle by NMDA antagonists in the amygdala. Nature 345:716-718.
45. Mishkin M, Aggleton JP (1981) Multiple functional contributions of the amygdala in the monkey. In: The amygdaloid complex (Ben-Ari Y, ed), pp 409-420. Amsterdam: Elsevier/North-Holland Biomedical.
46. Mitchell SJ, Richardson RT, Baker FH, DeLong MR (1987) The primate globus pallidus: neuronal activity related to direction of movement. Exp Brain Res 68:491-505.
47. Murray EA, Gaffan D, Mishkin M (1993) Neural substrates of visual stimulus-stimulus association in rhesus monkeys. J Neurosci 13:4549-4561.
48. Nishijo H, Norgren R (1990) Responses from parabrachial gustatory neurons in behaving rats. J Neurophysiol 63:707-724.
49. Nishijo H, Norgren R (1991) Parabrachial neuronal activity during licking by rats. J Neurophysiol 66:974-985.
50. Nishijo H, Ono T, Nishino H (1988a) Topographic distribution of modality-specific amygdalar neurons in alert monkey. J Neurosci 8:3556-3569.
51. Nishijo H, Ono T, Nishino H (1988b) Single neuron responses in amygdala of alert monkey during complex sensory stimulation with effective significance. J Neurosci 8:3570-3583.
52. Ono T, Sasaki K, Nakamura K, Norgren R (1985) Integrated lateral hypothalamic neural responses to natural and artificial rewards and cue signals in the rat. Brain Res 327:303-306.
53. Palestini M, Mariotti M, Velasco JM, Formenti A, Mancia M (1987) Medialis dorsalis thalamic unitary response to tooth pulp stimulation and its conditioning by brainstem and limbic activation. Neurosci Lett 78:161-165.
54. Paxinos G, Watson C (1986) The rat brain in stereotaxic coordinates, 2nd Ed. San Diego: Academic.
55. Peinado-Manzano MA, Pozo-Garcia R (1991) The role of different nuclei of the thalamus in processing episodic information. Behav Brain Res 45:17-27.
56. Ray JP, Price JL (1992) The organization of the thalamocortical connections of the mediodorsal thalamic nucleus in the rat, related to the ventral forebrain-prefrontal cortex topography. J Comp Neurol 323:167-197.
57. Rudy JW, Sutherland RJ (1993) The hippocampal formation is necessary for rats to learn and remember configural discriminations. Behav Brain Res 34:97-109.
58. Russchen FT, Amaral DG, Price JL (1987) The afferent input to the magnocellular division of the mediodorsal thalamic nucleus in the monkey, Macaca fascicularis. J Comp Neurol 256:175-210.
59. Sarter M, Markowitsch HJ (1983) Convergence of basolateral amygdaloid and mediodorsal thalamic projections in different areas of the frontal cortex in the rat. Brain Res Bull 10:607-622.
60. Sarter M, Markowitsch HJ (1984) Collateral innervation of the medial and lateral prefrontal cortex by amygdaloid, thalamic, and brain-stem neurons. J Comp Neurol 224:445-460.
61. Schulman S (1957) Bilateral symmetrical degeneration of the thalamus: a clinico-pathological study. J Neuropathol Exp Neurol 16:446-470.
62. Shima K, Aya K, Mushiake H, Inase M, Aizawa H, Tanji J (1991) Two movement-related foci in the primate cingulate cortex observed in signal-triggered and self-paced forelimb movements. J Neurophysiol 65:188-202.
63. Slotnick BM, Risser JM (1990) Odor memory and learning in rats with lesions of the lateral olfactory tract and mediodorsal thalamic nucleus. Brain Res 529:23-29.
64. Squire LR, Moore RY (1979) Dorsal thalamic lesion in a noted case of human memory dysfunction. Ann Neurol 6:503-506.
65. Staubli U, Schottler F, Nejat-Bina D (1987) Role of dorsomedial thalamic nucleus and piriform cortex in processing olfactory information. Behav Brain Res 25:117-129.
66. Stokes KA, Best PJ (1990) Mediodorsal thalamic lesions impair "reference" and "working" memory in rats. Physiol Behav 47:471-476.
67. Tanji J, Kurata K (1982) Comparison of movement-related activity in two cortical motor areas of primates. J Neurophysiol 48:633-653.
68. Uwano T, Nishijo H, Ono T, Tamura R (1995) Neuronal responsiveness to various sensory stimuli, and associative learning in the rat amygdala. Neuroscience 68:339-361.
69. Victor M, Adams RD, Collins GH (1971) The Wernicke-Korsakoff Syndrome. Philadelphia: Davis.
70. Waring AE, Means LW (1976) The effect of medial thalamic lesions on emotionality, activity, and discrimination learning in the rat. Physiol Behav 17:181-186.
71. Weiskrantz L (1956) Behavioral changes associated with ablation of the amygdaloid complex in monkeys. J Comp Physiol Psychol 49:381-391.
72. Whishaw IQ, Tomie JA (1995) Rats with fimbria-fornix lesions can acquire and retain a visual-tactile transwitching (configural) task. Behav Neurosci 109:607-612.
73. Whishaw IQ, Tomie JA, Kolb B (1992) Ventrolateral prefrontal cortex lesions in rats impair the acquisition and retention of a tactile-olfactory configural task. Behav Neurosci 106:597-603.
74. Zola-Morgan S, Squire LR (1985) Amnesia in monkeys after lesions of the mediodorsal nucleus of the thalamus. Ann Neurol 17:558-564.