An approach to predictive testing of contact sensitizers in vitro by monitoring their influence on endocytotic mechanisms

International Archives of Allergy and Immunology

Volumn 111, Issue 1, 1996, Pages 64-70

  Lempertz, Uwe ^a   Kühn, Ulrich ^a   Knop, Jürgen ^a   Becker, Detlef ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

Contact sensitizers; Endocytosis; Langerhans cells

Indexed keywords

CONCANAVALIN A; FLUOROCHROME; HAPTEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MONOCLONAL ANTIBODY; PHORBOL 13 ACETATE 12 MYRISTATE;

ANIMAL CELL; ANTIGEN ANTIBODY COMPLEX; ARTICLE; CELL SUSPENSION; CONTACT SENSITIVITY; CONTROLLED STUDY; ENDOCYTOSIS; EPIDERMIS CELL; FEMALE; FLOW CYTOMETRY; LANGERHANS CELL; MALE; MOUSE; NONHUMAN; PH; PRIORITY JOURNAL; RISK; SKIN ALLERGY;

EID: 0029830002     PISSN: 10182438     EISSN: 14230097     Source Type: Journal    
DOI: 10.1159/000237347     Document Type: Article

References (26)

1. Kligman AM, Basketter DA: A critical commentary and updating of the guinea pig maximization test. Contact Dermatitis 1995:32:129-134.
2. Gerberick GF, House RV, Flctschcr ER, Rvan CA: Examination of the local lymph node assay for use in contact sensitization risk assessment. Fundam Appl Toxicol 1992;19:438-445.
3. Hauser C, Katz SI: Activation and expansion of hapten- and protein-specific T helper cells from nonsensitized mice. Proc Natl Acad Sei USA 1988;85:5625-5628.
4. Moulon C, Peguet-Navarro J, Courtellemont P, Redziniak G, Schmitt D: In vitro primary sensitization and restimulation of hapten-specific T cells by fresh and cultured human epidermal Langcrhans'cclls. Immunology 1993:80:373-379.
5. Yokozcki H, Katayama I, Nishioka K: Experimental study for the development of an in vitro test for contact allergens. Int Arch Allergy Immunol 1995:106:394-400.
6. Stingl GL, Katz SI, Shevach EM, Rosenthal AS, Green I: Analogous functions of macrophages and Langerhans cells in the initiation of the immune response. J Invest Dermatol 1978;71:59-64.
7. Toews GB, Bergstresser PR, Streilein JW: Epidermal Langerhans cell density determines whether contact hypersensitivity or unrcspon-siveness follows skin painting with DNFB. J Immunol 1980:124:445-453.
8. Streilcin JW: Antigen-presenting cells in tile induction of contact hypersensitivity in mice: Evidence that Langerhans cell are sufficient but not required. J Invest Dermatol 1989:93:443-448.
9. Enk AH, Katz SI: Early molecular events in the induction phase of contact sensitivity. Proc Natl Acad Sci USA 1992;89:1398-1402.
10. Becker D, Neiss U, Neis S, Reske K, Knop J: Contact allergens modulate the expression of MHC class II molecules on murine epidermal Langerhans cells by endocytotic mechanisms. J Invest Dermatol 1992:98:700-705.
11. Becker D, Mohamadzadch M, Reske K, Knop J: Increased level of intracellular MI IC class II molecules in murine Langerhans cells following in vivo and in vitro administration of contact allergens. J Invest Dermatol 1992:99:545-549.
12. Becker D, Kolde G, Reske K, Knop J: An in vitro test for endocytotic activation of murine epidermal Langerhans cells under the influence of contact allergens. J Immunol Methods 1994: 169:195-204.
13. Kappler JW, Skidmore B, White J, Marrack P: Antigen-inducible. H-2-restricted, intcrieu-kin-2-producing T cell hybridomas. J Exp Med 1981:153:1198-1214.
14. Girolomoni G, Cruz PD Jr, Bergstresser PR: Internalization and acidification of surface HLA-DR molecules by epidermal Langerhans cells: A paradigm for antigen processing. J Invest Dermatol 1990;94:753-760.
15. Yoshimori T, Yamamoto A, Moriyama Y, Futai M, Tashiro Y: Bafilomycin A, a specific inhibitor of vacuolar-type 11 -ATPasc. inhibits acidification and protein degradation in lysosomes of cultured cells. J BiolChem 1991:266:17707-17712.
16. Nakamura K, Ishii A, Tamaki K: Subpopulation of murine epidermal Langerhans cells identified by lectin-binding sites. Arch Dermatol Res 1990;282:253-257.
17. Nishizuka Y: Studies and prospectives of the protein kinase C family for cellular regulation. Cancer 1989:63:1892-1903.
18. Okuda K, Ishii N, Ikezawa Z, Tani K, Ishigat-subo Y: Genetic control of contact hypersensitivity. I, 1-A subregion as well as non-H-2 loci codes for the gene of 2.4-dinitro-l-fluoroben-zene antigen. Eur J Immunol 1980:10:969-971.
19. Menne T, Frosch PJ, Veien NK, Hannuksela M, Bjorkner B, Lachapelle JM, White IR, Vejls-gaard G, Schubert HJ, Andersen KE: Contact sensitization to 5-chloro-2-methyl-4-isothiazo-lin-3-onc and 2-methyl-4-isothiazolin-3-one (MCI/Ml). A European multicentre study. Contact Dermatitis 1991;24:334-341.
20. Maurer T, Kimber I: Draining lymph node cell activation in guinea pigs: Comparisons with the murine local lymph node assay. Toxicology 1991;69:209-218.
21. Ishii N, Ishii H, Ono H, Horiuchi Y, Nakajima H, Aoki I: Genetic control of nickel sulfate de-layed-type hypersensitivity. J Invest Dermatol 1990;94:673-676.
22. Mor S, Ben-Efraim S, Lcibovici J, Ben David A: Successful contact sensitization to chromate in mice. Int Arch Allergy Appl Immunol 1988: 85:452-457.
23. Fuchs Th, Enders F, Przybilla B, Ippen H, Aber-er W, Bauer R, Schulzc-Dirks A, Frosch PJ, Peters K-P, Gailhofer G, Steffan M-A, Wassilew SW. Ilcnscl O. Gehring W, Lischka G, Agathos M, Breit R, Balmier F, Stary A, Brasch J: Contact allergy to Euxyl K 400. Results of a multi-center study of the German Contact Allergy Group. Dermatosen 1991;39:151-153.
24. Hausen BM: The sensitizing potency of Euxyl K 400 and its components l,2-dibromo-2,4-di-cyanobutane and phenoxyethanol. Contact Dermatitis 1993;28:149-153.
25. Menne T, Hjorth N: Routine patch testing with paraben esters. Contact Dermatitis 1988:19: 189-191.
26. Rastogi SC, Schouten A, de Kruif N, Weijland JW: Contents of methyl-, ethyl-, propyl-, butyl-and benzylparaben in cosmetic products. Contact Dermatitis 1995:32:28-30.