Interleukin-10 inhibited the expression of tumor antigens and major histocompatibility complex antigen on EJ-ras oncogene transformants

Artificial Organs

Volumn 20, Issue 8, 1996, Pages 895-897

  Tsuruma, Tetsuhiro ^a   Yagihashi, Atsuhito ^a   Torigoe, Toshihiko ^a   Okada, Yojiro ^a   Sato, Noriyuki ^a   Kikuchi, Kokichi ^a   Hirata, Koichi ^a  

^a SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Interleukin 10; Major histocompatibility complex antigen class I; Natural killer cell; Tumor antigens

Indexed keywords

CELL CULTURE; CELLS; MOLECULES; MONOCLONAL ANTIBODIES; RATS; TUMORS;

CELL-BE; CELL/B.E; CLASS I; CYTOKINES; INTERLEUKIN-10; MAJOR HISTOCOMPATIBILITY COMPLEX; MAJOR HISTOCOMPATIBILITY COMPLEX ANTIGEN CLASS I; NATURAL KILLER CELLS; TRANSFORMANTS; TUMOR ANTIGEN;

ANTIGENS;

INTERLEUKIN 10; TUMOR ANTIGEN;

ANIMAL CELL; ARTICLE; CELL CULTURE; FETUS; HISTOCOMPATIBILITY COMPLEX; NATURAL KILLER CELL; NONHUMAN; ONCOGENE EJ RAS; PRIORITY JOURNAL; RAT;

ANIMALIA;

EID: 0029829974     PISSN: 0160564X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1525-1594.1996.tb04565.x     Document Type: Article

References (14)

1. Fong TAT, Mosmann TR. Alloreactive murine CD8 T cell clones secrete the Th 1 pattern of cytokines. J Immunol 1990; 144:1744-52.
2. Chen WF, Zlotnik A. IL-10: A novel cytotoxic T cell differentiation factor. J Immunol 1991;147:528-34.
3. Taga K, Tosato G. IL-10 inhibits human T cell proliferation and IL-2 production. J Immunol 1992;148:1143-8.
4. de Waal Malefyt R, Abrams J, Bennett B, Figdor CG, de Vries JE. Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: An autoregulatory role of IL-10 produced by monocytes. J Exp Med 1991;74:1209-20.
5. Gazzinelli RT, Oswald IP, James SL, Sher A. IL-10 inhibits parasite killing and nitrogen oxide production by IFN-γ-activated macrophages. J Immunol 1992;48:1792-6.
6. Bogdan C, Vodovotz Y, Nathan C. Macrophage deactivation by interleukin 10. J Exp Med 1991;74:1549-55.
7. Cunha FQ, Moncada S, Liew FY. Interleukin-10 (IL-10) inhibits the induction of nitric oxide syntheses by interferon-γ in murine macrophages. Biochem Biophys Res Commun 1992;182:1155-9.
8. Oswald IP, Gazzinelli RT, Sher A, James SL. IL-10 synergizes with IL-4 and transforming growth factor-β to inhibit macrophage cytotoxic activity. J Immunol 1992;148: 3578-83.
9. de Waal Malefyt R, Haanen J, Spits H, Roncarcolo MG, de Velde A, Figdor C, Johnson K, Kastelein R, Yssel H, de Vries JE. Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression. J Exp Med 1991;174:915-24.
10. Chao, S-H, Chu S-H, Lee S-C, Lin J-K, Chen K-M. Interleukin-10 (IL-10) prevents primary nonfunction in allogeneic islet transplantation. Transplant Proc 1995;27:602-4.
11. Sato N, Torigoe T, Yagihashi A, Okubo M, Takahashi S, Takahashi H, Enomoto K, Yamashita T, Fujinaga K. Kikuchi K. Assessment and establishment of a WKA rat fetus derived cell for the oncogene transfection. Tumor Res 1987; 22:15-26.
12. Yagihashi A, Sato N, Torigoe T, Okubo N, Konno A, Takahashi N, Yamashita T, Fujinaga K, Kuzumaki N, Kikuchi K. Identification of the transformation-associated cell surface antigen expressed on the rat fetus-derived fibroblast. Cancer Res 1988;48:2798-804.
13. Salazar-Onfray F, Petersson M, Franksson L, Matsuda M. Blankenstein T, Karre K, Kiessling R. IL-10 converts mouse lymphoma cells to a CTL-resistant, NK-sensitive phenotype with low but peptide-inducible MHC class 1 expression. J Immunol 1995;154:6291-8.
14. Matsuda M, Salazar F, Petersson M, Masucci G, Hansson J, Pisa P, Zhang QJ, Masucci MG, Kiessling R. Interleukin 10 pretreatment protects target cells from tumor- and allospecific cytotoxic T cells and downregulates HLA class I expression. J Exp Med 1994;180:2371-6.