Characterization of substance P release from the intermediate area of rat thoracic spinal cord

Synapse

Volumn 23, Issue 4, 1996, Pages 265-273

  Yang, Ling ^a   Thomas, Nigel D ^b   Helke, Cinda J ^a  

^a UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

^b NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

Coexistence; Intermediolateral cell column; NK1 receptor; Sympathetic function; Tachykinins

Indexed keywords

2 METHYLSEROTONIN; 4 (4 METHYL 1 PIPERAZINYL) 7 TRIFLUOROMETHYLPYRROLO[1,2 A]QUINOXALINE; 5 AMINOVALERYLSUBSTANCE P [7-11][9 PROLINE 10 (N METHYLLEUCINE)]; 5 METHOXY 3 (1,2,3,6 TETRAHYDRO 4 PYRIDYL) 1H INDOLE; 5,7 DIHYDROXYTRYPTAMINE; NEUROKININ 1 RECEPTOR; NEUROKININ 1 RECEPTOR ANTAGONIST; NEUROKININ A; NEUROKININ A [3-10][3 LYSINE 8 GLYCINE GAMMA LACTAM 9 LEUCINE]; POTASSIUM ION; PRESYNAPTIC RECEPTOR; PROTIRELIN; PYRO 2 AMINOADIPYLHISTIDYLTHIAZOLIDINE 4 CARBOXAMIDE; SEROTONIN; SUBSTANCE P; SUBSTANCE P DERIVATIVE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEPOLARIZATION; HORMONE RELEASE; MALE; NERVE ENDING; NONHUMAN; PRESYNAPTIC INHIBITION; PRIORITY JOURNAL; RAT; SEROTONINERGIC NERVE; SPINAL CORD DORSAL HORN; SPINAL CORD VENTRAL HORN; SYMPATHETIC FUNCTION; THORACIC SPINAL CORD;

5,7-DIHYDROXYTRYPTAMINE; ANIMALS; AUTONOMIC FIBERS, PREGANGLIONIC; MALE; NERVE ENDINGS; NEUROKININ A; NEUROTOXINS; POTASSIUM; RATS; RATS, SPRAGUE-DAWLEY; SEROTONIN; SEROTONIN AGENTS; SPINAL CORD; SUBSTANCE P; THORAX; THYROTROPIN-RELEASING HORMONE;

EID: 0029829962     PISSN: 08874476     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2396(199608)23:4<265::AID-SYN4>3.0.CO;2-5     Document Type: Article

References (42)

1. Backman, S.B., and Henry, J.L. (1984) Effects of substance P and thyrotropin-releasing hormone on sympathetic neurons in the upper thoracic intermediolateral nucleus of the rat. Can. J. Physiol. Pharmacol., 62:248-251.
2. Bartfai, T., Iverfeldt, K., Brodin, E., and Ogren, S.O. (1986) Functional consequences of coexistence of classical and peptide neurotransmitters. Pro. Brain Res., 68:321-330.
3. Baumgarten, H.G., Bjorklund, A., Lachenmayer, L., and Nobin, A. (1973) Evaluation of the effects of 5,7-dihydroxytryptamine on serotonin and catecholamine neurons in the rat CNS. Acta. Physiol. Scand. Suppl., 391:1-19.
4. Beaudt, A., and Descarries, L. (1987) Ultrastructural identification of serotonin neurons. In: Monoaminergic Neurons: Light Microscopy and Ultrastructure. H.W.M. Steinbusch, ed. John Wiley, Chichester, pp. 265-313.
5. Bourgoin, S., Pohl, M., Mauborgne, A., Benoliel, J.J., Collin, E., Hamon, M., and Cesselin, F. (1993) Monoaminergic control of the release of calcitonin gene-related peptide- and substance P-like materials from rat spinal cord slices. Neuropharmacology, 32:633-640.
6. Bucsics, A., Mayer, N., Pabst, M.A., and Lembeck, F. (1984) Distribution of spinal cord nerve endings containing various neurotransmitters on a continuous density gradient. J. Neurochem., 42:692-697.
7. Buma, P. (1989) Synaptic and non-synaptic release of neuromediators in the central nervous system. Act. Morphol. Neurol. Scand., 26:81-113.
8. Charlton, C.G., and Heike, C.J. (1985) Autoradiographic localization and characterization of spinal cord substance P binding sites: High densities in sensory, autonomic, phrenic, and Onuf's motor nuclei. J. Neurosci., 5:1653-1661.
9. Chen, J.J., Barber, L., Dymshitz, J., and Vasko, M.R. (1993) Selective peptidase inhibitors enhance recovery of substance P and calcitonin gene-related peptide released from rat spinal cord slices. Soc. Neurosci. Abstr., 19:1364.
10. Collin, E., Mauborgne, A., Bourgoin, S., Mantelet, S., Ferhat, L., Hamon, M., and Cesselin, F. (1992) Kappa-/Mu-receptor interactions of the opiate control of the in vivo release of substance P-like material from the rat spinal cord. Neuroscience, 51:347-355.
11. Davis, B.M., Krause, J.E., McKeley, J.F., and Cabot, J.B. (1984) Effects of spinal lesions on substance P levels in the rat sympathetic preganglionic cell column: Evidence for local spinal regulation. Neuroscience, 13:1311-1326.
12. Franck, J., Brodin, E., and Fried, G. (1993) Differential release of endogenous 5-hydroxytryptamine, substance P, and neurokinin A from rat ventral spinal cord in response to electrical stimulation. J. Neurochem., 61:704-711.
13. Fried, G., Franck, J., Brodin, E., Born, W., Fisher, J.A., Hiort, W., and Hokfelt, T. (1989) Evidence for differential storage of calcitonin generelated peptide, substance P and serotonin in synaptosomal vesicles of rat spinal cord. Brain Res., 499:315-320.
14. Hancock, M.B., and Peveto, C.A. (1979) A preganglionic autonomic nucleus in the dorsal gray commissure of the lumbar spinal cord of the rat. J. Comp. Neural., 201:65-79.
15. Helke, C.J., Jacobowitz, D.M., and Thoa, N.B. (1981) Capsaicin and potassium evoked substance P release from the nucleus tractus solitarius and spinal trigeminal nucleus in vitro. Life Sci., 29:1779-1785.
16. Heike, C.J., Neil, J.J., Massari, V.J., and Loewy, A.D. (1982) Substance P neurons project from the ventral medulla to the intermediolateral cell column and ventral horn in the rat. Brain Res., 243:147-152.
17. Heike, C.J., Charlton, C.G., and Wiley, R.G. (1986) Studies on the cellular localization of spinal cord substance P receptors. Neuroscience, 19:523-533.
18. Heike, C.J., Phillips, E.T., and O'Neill, J.T. (1987a) Regional peripheral and CNS hemodynamic effects of intrathecal administration of a substance P receptor agonist. J. Autonomic Nervous Sys., 21:1-7.
19. Helke, C.J., Phillips, E.T., and O'Neill, J.T. (1987b) Intrathecal administration of a substance P receptor antagonist: Studies on peripheral and central nervous system hemodynamics and on specificity of action. J. Pharmacol. Exp. Ther., 242:131-136.
20. 3H]serotonin from tissue slices of rat ventral spinal cord. Acta Physiol. Scand., 137:63-71.
21. Jansen, I., Alafaci, C., McCulloch, J., Uddman, R., and Edvinsson, L. (1991) Tachykinins (substance P, neurokinin A, neuropeptide K, and neurokinin B) in the central circulation: Vasomotor responses in vitro and in situ. J. Cerebral Blood Flow and Metabolism, 11:567-575.
22. Keeler, J.R., Charlton, C.G., and Heike, C.J. (1985) Cardiovascular effects of spinal cord substance P: Studies with a stable receptor agonist. J. Pharmacol. Exp. Ther., 233:755-760.
23. Krukoff, T.L., Ciriello, J., and Calaresu, F.R. (1985) Segmental distribution of peptide-like immunoreactivity in cell bodies of the thoracolumbar sympathetic nuclei in the cat. J. Comp. Neurol., 240:90-102.
24. Lowry, O.H., Rosebrough, N.Y., Farr, A.L., and Randall, R.J. (1951) Protein measurement with the folin phenol reagent. J. Bio. Chem., 193:266-275.
25. Lundberg, J., and Hökfelt, T. (1983) Co-existence of peptides and classical neurotransmitters. Trends Neurosci., 6:325-333.
26. Maggi, C.A., Patacchini, R., Rovero, P., and Giacheyi, A. (1993) Tachykinin receptors and tachykinin receptor antagonists. J. Auto. Pharmacol., 13:23-93.
27. Malcangio, M., and Bowery, N.G. (1994) Effect of the tachykinin NK, receptor antagonists, RP 67580 and SR 140333, on electricallyevoked substance P release from rat spinal cord. Br. J. Pharmacol., 113:635-641.
28. Manaker, S., Winokur, A., Rostene, W.H., and Rainbow, T.C. (1985) Autoradiographic localization of thyrotropin-releasing hormone receptors in the rat central nervous system. J. Neurosci., 5:167-174.
29. Mantyh, P.W., Gates, T.S., Mantyh, C.R., and Maggio, J.E. (1989) Autoradiographic localization and characterization of tachykinin receptor binding sites in the rat brain and peripheral tissues. J. Neurosci., 9:258-279.
30. Nevin, K., Zhuo, H., and Helke, C.J. (1994) Neurokinin A coexists with substance P and serotonin in ventral medullary spinally projecting neurons of the rat. Peptides, 15:1003-1011.
31. Pelletier, G., Steinbusch, H.W.M., and Verhofstad, A.J. (1981) Immunoreactive substance P and serotonin present in the same densecore vesicles. Nature (England), 293:71-72.
32. Petras, J.M., and Cummings, J.F. (1972) Autonomic neurons in the spinal cord of the Rhesus monkey: A correlation of the findings of cytoarchitectonics and sympathectomy with fiber degeneration following dorsal rhizotomy. J. Comp. Neurol., 146:189-218.
33. Pham, T., and Couture, R. (1993) Inhibitory action of (+/-)CP-96,345 on the cardiovascular responses to intrathecal substance P and neuropeptide K in the conscious freely moving rat. Naunyn Schmiedeberg's Arch. Pharmacol., 347:34-41.
34. Poulat, P., Marlier, L., Rajaofetra, N., and Privat, A. (1992) 5-Hydroxytryptamine, substance P and thyrotropin-releasing hormone synapses in the inermediolateral cell column of the rat thoracic spinal cord. Neurosci. Lett., 136:19-22.
35. 3 receptor antagonists inhibit sensory neuropeptide release from the rat spinal cord. Neuroreport, 2:104-106.
36. Sasek, C.A., Wessendorf, M.W., and Helke, C.J. (1990) Evidence for co-existence of thyrotropin-releasing hormone, substance P and serotonin in ventral medullary neurons that project to the intermediolateral cell column in the rat. Neuroscience, 35:105-119.
37. Sharif, N.A., and Burt, D.R. (1983) Rat brain TRH receptors: Kinetics, pharmacology, distribution and ionic effects. Reg. Peptides, 7:399-411.
38. (1-17). J. Pharmacol. Exp. Ther., 252:539-545.
39. Wessendorf, M.W., and Elde, R. (1987) The coexistence of serotonin-and substance P-like immunoreactivity in the spinal cord of the rat as shown by immunofluorescent double labeling. J. Neurosci., 7:2352-2363.
40. Yang, L., and Heike, C.J. (1995) Effects of coexisting neurochemicals on the release of serotonin from the intermediate area of rat thoracic spinal cord. Synapse, 21:319-323.
41. 3H]5-hydroxytryptamine from the intermediate area of rat thoracic spinal cord is modulated by presynaptic autoreceptors. Synapse, 18:198-204.
42. Yarnrough, G.G., and McGuffin-Clineschmidt, J.C. (1979) MK-771 induced electromyographic (EMG) activity in the rat: Comparison with thyrotropin-releasing hormone (TRH) and antagonism by neurotensin. Eur. J. Pharmacol., 60:41-46.