Sequence analysis of hypervariable region of hepatitis C virus (HCV) associated with immune complex in patients with chronic HCV infection

Journal of Infectious Diseases

Volumn 174, Issue 6, 1996, Pages 1316-1320

  Aiyama, Toshiyuki ^a   Yoshioka, Kentaro ^a   Okumura, Akihiko ^a   Takayanagi, Masahiro ^a   Iwata, Kazuo ^a   Ishikawa, Tetsuya ^a   Kakumu, Shinichi ^a  

^a NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS RNA;

ADULT; AGED; AMINO ACID SEQUENCE; ANTIBODY RESPONSE; ANTIGEN ANTIBODY COMPLEX; ARTICLE; CLINICAL ARTICLE; FEMALE; FRACTIONATION; HEPATITIS C VIRUS; HUMAN; MALE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; VIRUS INFECTION;

EID: 0029829717     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1093/infdis/174.6.1316     Document Type: Article

References (15)

1. Choo QL, Kuo G, Weiner AJ, Overby LR, Bradley DW, Houghton M. Isolation of a cDNA derived from a blood borne non-A, non-B viral hepatitis genome. Science 1989;244:359-62.
2. Miyamoto H, Okamoto H, Sato K, Tanaka T, Mishiro S. Extraordinarily low density of hepatitis C virus estimated by sucrose density gradient centrifugation and the polymerase chain reaction. J Gen Virol 1992;73:715-8.
3. Hijikata M, Shimizu YK, Kato H, et al. Equilibrium centrifugation studies of hepatitis C virus: evidence for circulating immune complexes. J Virol 1993;67:1953-8.
4. Kanto T, Hayashi H, Takehara T, et al. Buoyant density of hepatitis C virus recovered from infected hosts: two different features in sucrose equilibrium density-gradient centrifugation related to degree of liver inflammation. Hepatology 1994;19:296-302.
5. Tanaka K, Aiyama T, Imai J, Morishita Y, Fukatsu T, Kakumu S. Serum cryoglobulin and chronic hepatitis C virus disease among Japanese patients. Am J Gastroenterol 1995;90:1847-52.
6. Lunel F, Musset L, Cacoub P, et al. Cryoglobulinemia in chronic liver diseases: role of hepatitis C virus and liver damage. Gastroenterology 1994;106:1291-300.
7. Shimizu YK, Hijikata M, Iwamoto A, Alter HJ, Purcell RH, Yoshikura H. Neutralizing antibodies against hepatitis C virus and the emergence of neutralization escape mutant viruses. J Virol 1994;68:1494-500.
8. Desmet VJ, Gerber M, Hoofnagle JH, Manns M, Scheuer PJ. Classification of chronic hepatitis: diagnosis, grading, and staging. Hepatology 1994;19:1513-20.
9. Musset L, Diemert MC, Taibi F, et al. Characterization of cryoglobulins by immunoblotting. Clin Chem 1992;38:798-802.
10. Havel RJ, Howard AE, Bragton JH. The distribution and chemical composition of ultra centrifugally separated lipoproteins in human serum. J Clin Invest 1955;34:1345-53.
11. Yoshioka K, Kakumu S, Wakita T, et al. Detection of hepatitis C virus by polymerase chain reaction and response to interferon-α therapy: relationship to genotypes of hepatitis C virus. Hepatology 1992;16:293-9.
12. Okamoto H, Sugiyama Y, Okada S, et al. Typing hepatitis C virus by polymerase chain reaction with type-specific primers: application to clinical surveys and tracing infectious sources. J Gen Virol 1992;73:673-9.
13. Simmonds P, McOmish F, Yap PL, et al. Sequence variability in 5′ non-coding region of hepatitis C virus: identification of a new virus type and restrictions on sequence diversity. J Gen Virol 1993;74:661-8.
14. Kato N, Hijikata M, Ootsuyama Y, et al. Molecular cloning of the human hepatitis C virus genome from Japanese patients with non-A, non-B hepatitis. Proc Natl Acad Sci USA 1990;87:9524-8.
15. Wei X, Ghosh SK, Taylor ME, et al. Viral dynamics in human immunodeficiency virus type 1 infection. Nature 1995;373:117-22.