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Volumn 270, Issue 6 33-6, 1996, Pages

Inhibition of rat sinusoidal GSH transporter by thioethers: Specificity, sidedness, and kinetics

Author keywords

cystathionine; functional expression; hepatocellular transport; methionine; reduced glutathione; S adenosyl L methionine; Xenopus oocytes

Indexed keywords

CYSTATHIONINE; GLUTATHIONE; METHIONINE; S ADENOSYLMETHIONINE; SULFIDE;

EID: 0029829429     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.1996.270.6.g969     Document Type: Article
Times cited : (13)

References (26)
  • 1
    • 0021165902 scopus 로고
    • Inhibition of glutathione efflux from isolated hepatocytes by methionine
    • Aw, T. Y., M. Ookhtens, and N. Kaplowitz. Inhibition of glutathione efflux from isolated hepatocytes by methionine. J. Biol. Chem. 259: 9355-9358, 1984.
    • (1984) J. Biol. Chem. , vol.259 , pp. 9355-9358
    • Aw, T.Y.1    Ookhtens, M.2    Kaplowitz, N.3
  • 2
    • 0022493791 scopus 로고
    • Mechanisms of inhibition of glutathione efflux by methionine from isolated rat hepatocytes
    • Gastrointest. Liver Physiol. 13
    • Aw, T. Y., M. Ookhtens, and N. Kaplowitz. Mechanisms of inhibition of glutathione efflux by methionine from isolated rat hepatocytes. Am. J. Physiol. 250 (Gastrointest. Liver Physiol. 13): G354-G361, 1986.
    • (1986) Am. J. Physiol. , vol.250
    • Aw, T.Y.1    Ookhtens, M.2    Kaplowitz, N.3
  • 3
    • 0022017210 scopus 로고
    • Sulfobromophthalein inhibition of glutathione and methyl mercury secretion into bile
    • Gastrointest. Liver Physiol. 11
    • Ballatori, N., and T. W. Clarkson. Sulfobromophthalein inhibition of glutathione and methyl mercury secretion into bile. Am. J. Physiol. 248 (Gastrointest. Liver Physiol. 11): G238-G245, 1985.
    • (1985) Am. J. Physiol. , vol.248
    • Ballatori, N.1    Clarkson, T.W.2
  • 4
    • 0028148189 scopus 로고
    • Identification and characterization of high and low affinity transport systems for reduced glutathione in liver cell canalicular membranes
    • Ballatori, N., and W. J. Dutczak. Identification and characterization of high and low affinity transport systems for reduced glutathione in liver cell canalicular membranes. J. Biol. Chem. 267: 19731-19737, 1994.
    • (1994) J. Biol. Chem. , vol.267 , pp. 19731-19737
    • Ballatori, N.1    Dutczak, W.J.2
  • 5
    • 0019165593 scopus 로고
    • Involvement of the cystathionine pathway in the biosynthesis of glutathione by isolated rat hepatocytes
    • Beatty, P. W., and D. J. Reed. Involvement of the cystathionine pathway in the biosynthesis of glutathione by isolated rat hepatocytes. Arch. Biochem. Biophys. 204: 80-87, 1980.
    • (1980) Arch. Biochem. Biophys. , vol.204 , pp. 80-87
    • Beatty, P.W.1    Reed, D.J.2
  • 6
    • 0023079953 scopus 로고
    • High performance liquid chromatography of thiols and disulfides
    • Fariss, M. W., and D. L. Reed. High performance liquid chromatography of thiols and disulfides. Methods Enzymol. 143: 101-109, 1987.
    • (1987) Methods Enzymol. , vol.143 , pp. 101-109
    • Fariss, M.W.1    Reed, D.L.2
  • 7
    • 16044368208 scopus 로고
    • The use of monochlorobimane to determine the levels and synthesis of hepatic glutathione
    • Fernández-Checa, J. C., and N. Kaplowitz. The use of monochlorobimane to determine the levels and synthesis of hepatic glutathione. Anal. Biochem. 212: 190-197, 1990.
    • (1990) Anal. Biochem. , vol.212 , pp. 190-197
    • Fernández-Checa, J.C.1    Kaplowitz, N.2
  • 8
    • 0025347773 scopus 로고
    • Inhibition of GSH efflux from rat liver by methionine: Effects of GSH synthesis in cells and perfused organ
    • Gastrointest. Liver Physiol. 21
    • Fernández-Checa, J. C., T. Maddatu, M. Ookhtens, and N. Kaplowitz. Inhibition of GSH efflux from rat liver by methionine: effects of GSH synthesis in cells and perfused organ. Am. J. Physiol. 258 (Gastrointest. Liver Physiol. 21): G967-G973, 1990.
    • (1990) Am. J. Physiol. , vol.258
    • Fernández-Checa, J.C.1    Maddatu, T.2    Ookhtens, M.3    Kaplowitz, N.4
  • 9
    • 0024604102 scopus 로고
    • Effects of chronic ethanol feeding on rat hepatocytic glutathione. Relationship of cytosolic glutathione to efflux and mitochondrial sequestration
    • Fernández-Checa, J. C., M. Ookhtens, and N. Kaplowitz. Effects of chronic ethanol feeding on rat hepatocytic glutathione. Relationship of cytosolic glutathione to efflux and mitochondrial sequestration. J. Clin. Invest 83: 1247-1252, 1989.
    • (1989) J. Clin. Invest , vol.83 , pp. 1247-1252
    • Fernández-Checa, J.C.1    Ookhtens, M.2    Kaplowitz, N.3
  • 10
    • 0027247438 scopus 로고
    • Selective induction by phenobarbital of the electrogenic transport of glutathione and organic anions in rat liver canalicular membrane vesicles
    • Fernández-Checa, J. C., M. Ookhtens, and N. Kaplowitz. Selective induction by phenobarbital of the electrogenic transport of glutathione and organic anions in rat liver canalicular membrane vesicles. J. Biol. Chem. 268: 10836-10841, 1993.
    • (1993) J. Biol. Chem. , vol.268 , pp. 10836-10841
    • Fernández-Checa, J.C.1    Ookhtens, M.2    Kaplowitz, N.3
  • 11
    • 0023809525 scopus 로고
    • Effect of membrane potential and cellular ATP on glutathione efflux from isolated rat hepatocytes
    • Gastrointest. Liver Physiol. 18
    • Fernández-Checa, J. C., C. Ren, T. Y. Aw, M. Ookhtens, and N. Kaplowitz. Effect of membrane potential and cellular ATP on glutathione efflux from isolated rat hepatocytes. Am. J. Physiol. 255 (Gastrointest. Liver Physiol. 18): G403-G408, 1988.
    • (1988) Am. J. Physiol. , vol.255
    • Fernández-Checa, J.C.1    Ren, C.2    Aw, T.Y.3    Ookhtens, M.4    Kaplowitz, N.5
  • 12
    • 0026511550 scopus 로고
    • Canalicular transport of reduced glutathione in normal and mutant Eisai hyperbilirubinemic rats
    • Fernández-Checa, J. C., H. Takikawa, T. Horie, M. Ookhtens, and N. Kaplowitz. Canalicular transport of reduced glutathione in normal and mutant Eisai hyperbilirubinemic rats. J. Biol. Chem. 267: 1667-1673, 1992.
    • (1992) J. Biol. Chem. , vol.267 , pp. 1667-1673
    • Fernández-Checa, J.C.1    Takikawa, H.2    Horie, T.3    Ookhtens, M.4    Kaplowitz, N.5
  • 14
    • 0026564310 scopus 로고
    • Bidirectional mechanism of plasma membrane transport of reduced glutathione in intact rat hepatocytes and membrane vesicles
    • García-Ruiz, C., J. C. Fernández-Checa, and N. Kaplowitz, Bidirectional mechanism of plasma membrane transport of reduced glutathione in intact rat hepatocytes and membrane vesicles. J. Biol. Chem. 267: 22256-22264, 1992.
    • (1992) J. Biol. Chem. , vol.267 , pp. 22256-22264
    • García-Ruiz, C.1    Fernández-Checa, J.C.2    Kaplowitz, N.3
  • 18
    • 0024417885 scopus 로고
    • Hepatoprotective effects of cystathionine against acetaminophen-induced necrosis
    • Kitamura, Y., Y. Kamisaki, and T. Itoh. Hepatoprotective effects of cystathionine against acetaminophen-induced necrosis. J. Pharmacol. Exp. Ther. 250: 667-671, 1989.
    • (1989) J. Pharmacol. Exp. Ther. , vol.250 , pp. 667-671
    • Kitamura, Y.1    Kamisaki, Y.2    Itoh, T.3
  • 22
    • 0023711202 scopus 로고
    • Inhibition of glutathione efflux in the perfused rat liver and isolated hepatocytes by organic anions and bilirubin: Kinetics, sidedness and molecular forms
    • Ookhtens, M., I. Lyon, J. C. Fernández-Checa, and N. Kaplowitz. Inhibition of glutathione efflux in the perfused rat liver and isolated hepatocytes by organic anions and bilirubin: kinetics, sidedness and molecular forms. J. Clin. Invest. 82: 608-616, 1988.
    • (1988) J. Clin. Invest. , vol.82 , pp. 608-616
    • Ookhtens, M.1    Lyon, I.2    Fernández-Checa, J.C.3    Kaplowitz, N.4
  • 23
    • 0014481378 scopus 로고
    • Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues
    • Tietze, F. Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues. Anal. Biochem. 27: 502-522, 1969.
    • (1969) Anal. Biochem. , vol.27 , pp. 502-522
    • Tietze, F.1
  • 24
    • 0014772665 scopus 로고
    • A direct assessment of the importance of conjugation for biliary transport of sulfobromophthalein sodium
    • Whelam, G. J., J. Hock, and B. Combes. A direct assessment of the importance of conjugation for biliary transport of sulfobromophthalein sodium. J. Lab. Clin. Med. 75: 542-557, 1970.
    • (1970) J. Lab. Clin. Med. , vol.75 , pp. 542-557
    • Whelam, G.J.1    Hock, J.2    Combes, B.3
  • 25
    • 0028297372 scopus 로고
    • Expression cloning of a rat hepatic reduced glutathione transporter with canalicular characteristics
    • Yi, J.-R., S. Lu, J. C. Fernández-Checa, and N. Kaplowitz. Expression cloning of a rat hepatic reduced glutathione transporter with canalicular characteristics. J. Clin. Invest. 93: 1841-1845, 1994.
    • (1994) J. Clin. Invest. , vol.93 , pp. 1841-1845
    • Yi, J.-R.1    Lu, S.2    Fernández-Checa, J.C.3    Kaplowitz, N.4
  • 26
    • 0028898222 scopus 로고
    • Expression cloning of the cDNA for a polypeptide associated rat hepatic sinusoidal reduced glutathione transport: Characteristics and comparison with the canalicular transporter
    • Yi, J.-R., S. Lu, J. C. Fernández-Checa, and N. Kaplowitz. Expression cloning of the cDNA for a polypeptide associated rat hepatic sinusoidal reduced glutathione transport: characteristics and comparison with the canalicular transporter. Proc. Natl. Acad. Sci. USA 92: 1425-1429, 1995.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 1425-1429
    • Yi, J.-R.1    Lu, S.2    Fernández-Checa, J.C.3    Kaplowitz, N.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.