Receptor-specific somatostatin analogs: Correlations with biological activity

Metabolism: Clinical and Experimental

Volumn 45, Issue SUPPL.1, 1996, Pages 21-23

  Coy, David H ^a   Taylor, John E ^b  

^a TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOPEPTIN; BIM 23126; BIM 23268D; BIM 23508D; DEXTRO PHENYLALANYLPHENYLALANYLPHENYLALANYL DEXTRO TRYPTOPHYLLYSYLTHREONYLPHENYLALANYLTHREONINAMIDE; L 362856; OCTREOTIDE; SEGLITIDE; SOMATOSTATIN 14; SOMATOSTATIN 28; SOMATOSTATIN DERIVATIVE; SOMATOSTATIN RECEPTOR; UNCLASSIFIED DRUG; VAPREOTIDE;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; DOSE RESPONSE; DRUG ACTIVITY; HUMAN; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BINDING;

AMINO ACID SEQUENCE; ANIMALS; BINDING, COMPETITIVE; HUMANS; MOLECULAR SEQUENCE DATA; RATS; RECEPTORS, SOMATOSTATIN; SOMATOSTATIN;

EID: 0029829062     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0026-0495(96)90073-6     Document Type: Article

References (14)

1. Yamada Y, Post SR, Wang K, et al: Cloning and functional characterization of a family of human and mouse somatostatin receptors expressed in brain, gastrointestinal tract and kidney. Proc Natl Acad Sci USA 89:251-255, 1992
2. Yasuda K, Rens-Domiano S, Breder CD, et al: Cloning of a novel somatostatin receptor, SRIFTR-3, coupled to adenyl cyclase. J Biol Chem 267:20422-20428, 1992
3. Bruno J, Xu Y, Song J, et al: Molecular cloning and functional expression of brain specific somatostatin receptor. Proc Natl Acad Sci USA 89:11151-11155, 1992
4. O'Carroll A-M, Lolait SJ, Koni M, et al: Molecular cloning of the SRIFTR-5 receptor. Mol Pharmacol 42:939-946, 1992
5. Raynor K, Murphy WA, Coy DH, et al: Cloned somatostatin receptors: Identification of subtype selective peptides and demonstration of high affinity binding of linear peptides. Mol Pharmacol 43:838-844, 1993
6. Raynor K, O'Carroll A-M, Kong H, et al: Characterization of cloned somatostatin receptors SRIFTR4 and SRIFTR5. Mol Pharmacol 44:385-392, 1993
7. Rossowski WJ, Gu ZF, Akarca US, et al: Characterization of somatostatin receptor subtypes controlling rat gastric acid and pancreatic amylase release. Peptides 15:1421-1424, 1994
8. Lloyd KCK, Wang J, Aurang K, et al: Activation of somatostatin receptor subtype 2 inhibits acid secretion in rats. Am J Physiol 269:G102-G106, 1995
9. Rossowski WJ, Coy DH: Specific inhibition of rat pancreatic insulin or glucagon release by receptor-selective somatostatin analogues. Biochem Biophys Res Commun 206:341-346, 1994
10. Gu Z-F, Corletto VD, Mantey SA, et al: Somatostatin receptor subtype 3 mediates the inhibitory action of somatostatin on gastric smooth muscle cells. Am J Physiol 31:G739-G748, 1995
11. Patel YC, Srikant CB: Subtype selectivity of peptide analogues for all five cloned human somatostatin receptors. Endocrinology 135:2814-2817, 1994
12. O'Carroll AM, Raynor K, Lolait SJ, et al: Characterization of cloned human somatostatin receptor SRIFTR6. Mol Pharmacol 46:291-298, 1994
13. Moldovan S, Atiya A, Adrian T, et al: Somatostatin inhibits β-cell secretion via a subtype-2 somatostatin receptor in the isolated perfused human pancreas. J Surg Res 59:85-90, 1995
14. Vale W, Rivier J, Ling N, et al: Biologic and immunologic activities and applications of somatostatin analogues. Metabolism 27:1391-1401, 1978 (suppl 1)