Development of ventilatory responsiveness to progressive hypoxia and hypercapnia in low-birth-weight lambs

Journal of Applied Physiology

Volumn 81, Issue 4, 1996, Pages 1555-1561

  Moss, T J ^a   Davey, M G ^a   McCrabb, G J ^a   Harding, R ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

growth restriction; newborn; rebreathing; small for gestational age

Indexed keywords

CARBON DIOXIDE; OXYGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL CARBON DIOXIDE TENSION; ARTERIAL OXYGEN TENSION; ARTERIAL PH; ARTICLE; CONTROLLED STUDY; HYPERCAPNIA; HYPOXIA; LAMB; LOW BIRTH WEIGHT; NONHUMAN; PRIORITY JOURNAL; REBREATHING;

EID: 0029828672     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/jappl.1996.81.4.1555     Document Type: Article

References (30)

1. Alvaro, R., J. Alvarez, K. Kwiatkowski, D. Cates, and H. Rigatto. Small preterm infants (≤1500 g) have only a sustained decrease in ventilation in response to hypoxia. Pediatr. Res. 32: 403-406, 1992.
2. Bard, H., F. C. Battaglia, E. L. Makowski, and G. Meschia. The synthesis of fetal and adult hemoglobin in sheep during the perinatal period. Proc. Soc. Exp. Biol. Med. 139: 1148-1150, 1972.
3. Beal, S. Sudden infant death syndrome in twins. Pediatrics 84: 1038-1044, 1989.
4. Bonora, M., M. Boule, and H. Gautier. Diaphragmatic and ventilatory responses to alveolar hypoxia and hypercapnia in conscious kittens. J. Appl. Physiol. 72: 203-210, 1992.
5. Davey, M. G., T. J. Moss, G. J. McCrabb, and R. Harding. Prematurity alters hypoxic and hypercapnic ventilatory responses in developing lambs. Respir. Physiol. In press.
6. Duke, H. N., J. H. Green, and E. Neil. Carotid chemoreceptor impulse activity during inhalation of carbon monoxide mixtures. J. Physiol. Lond. 118: 520-527, 1952.
7. Edelman, N. H., S. Lahiri, L. Braudo, N. S. Cherniack, and A. P. Fishman. The blunted ventilatory response to hypoxia in cyanotic congenital heart disease. N. Engl. J. Med. 282: 405-411, 1970.
8. Eden, G. J., and M. A. Hanson. Maturation of the respiratory response to acute hypoxia in the newborn rat. J Physiol. Lond. 392: 1-9, 1987.
9. Eden, G. J., and M. A. Hanson. Effects of chronic hypoxia from birth on the ventilatory response to acute hypoxia in the newborn rat. J. Physiol. Lond. 392: 11-19, 1987.
10. Farber, J. R, H. N. Hultgren, and S. M. Tenney. Development of the chemical control of breathing in the Virginia opossum. Respir. Physiol 14: 267-277, 1972.
11. Fukuda, Y. Changes in ventilatory response to hypoxia in the rat during growth and aging. Pfluegers Arch. 421: 200-203, 1992.
12. Gaultier, C. Apnea and sleep state in newborns and infants. Biol. Neonate 65: 231-234, 1994.
13. Greenspan, J. S., S. Abbasi, and V. K. Bhutani. Sequential changes in pulmonary mechanics in the very low birth weight (≤1000 grams) infant. J. Pediatr. 113: 732-737, 1988.
14. Kumar, P., and M. A. Hanson. Re-setting of the hypoxic sensitivity of aortic chemoreceptors in the new-born lamb. J. Dev. Physiol 11:199-206, 1989.
15. Lahiri, S. Carotid body chemoreception: mechanisms and dynamic protection against apnea. Biol. Neonate 65:134-139, 1994.
16. Liggins, G. C., J. Schellenberg, M. Manzai, J. A. Kitterman, and C. H. Lee. Synergism of cortisol and thyrotropin-releasing hormone in lung maturation in fetal sheep. J. Appl. Physiol. 65: 1880-1884, 1988.
17. Lindroth, M., B. Johnson, H. Ahlström, and N. W. Svenningsen. Pulmonary mechanics in early infancy. Subclinical grunting in low-birth-weight infants. Pediatr. Res. 15: 979-984, 1981.
18. Marcus, C. L., W. B. Glomb, D. J. Basinski, S. L. Davidson Ward, and T. G. Keens. Developmental pattern of hypercapnic and hypoxic ventilatory responses from childhood to adulthood. J. Appl. Physiol 76: 314-320, 1994.
19. Moss, T. J., A. E. Jakubowska, G. J. McCrabb, K. Billings, and R. Harding. Ventilatory responses to progressive hypoxia and hypercapnia in developing sheep. Respir. Physiol. 100: 33-44, 1995.
20. Øyen, N., R. SKJæerven, R. E. Little, and A. J. Wilcox. Fetal growth retardation in sudden infant death syndrome (SIDS) babies and their siblings. Am. J. Epidemiol. 142: 84-90, 1995.
21. Phillipson, E. A., and L. F. Kozar, Effect of aging on metabolic respiratory control in sleeping dogs. Am. Rev. Respir. Dis. 147: 1521-1525, 1993.
22. Rees, S., A. D. Bocking, and R. Harding. Structure of the fetal sheep brain in experimental growth retardation. J. Dev. Physiol. 10: 211-224,1988.
23. Rees, S., J. Ng, K. Dickson, T. Nicholas, and R. Harding. Growth retardation and the development of the respiratory system in fetal sheep. Early Hum. Dev. 26: 13-27,1991.
24. Rees, S. M., and M. Tolcos. Chronic placental insufficiency in fetal guinea pigs affects neurochemical and neuroglial development but not neuronal numbers in the brainstem. Abstr. Soc. Neurosci. 25th Annu. Meet., San Diego, CA 21: 2016, 1995.
25. Robinson, J. J., I. McDonald, C. Fraser, and R. M. J. Crofts. Studies on reproduction in prolific ewes. I. Growth of the products of conception. J.Agric. Sci. 88: 539-552, 1977.
26. Robinson, J. S. Fetal growth and development. In: Turnbull's Obstetrics, edited by G. Chamberlain. London: Churchill Livingstone, 1995, p. 97-113.
27. Rona, R. J., M. C. Gulliford, and S. Chinn. Effects of prematurity and intrauterine growth on respiratory health and lung function in childhood. Br. Med. J. 306: 817-820,1993.
28. Spiers, P. S. Sibling birthweights and maternal age in SIDS cases. Growth 47: 104-108,1983.
29. Springer, C., D. M. Cooper, and K. Wasserman. Evidence that maturation of the peripheral chemoreceptors is not complete in childhood. Respir. Physiol. 74: 55-64, 1988.
30. Weese-Mayer, D. E., L. M. Klemka-Walden, G. A. Barkov, and J. L. Gingras. Effects of prenatal cocaine on the ventilatory response to hypoxia in newborn rabbits. Dev. Pharmacol. Ther. 18: 116-124, 1992.