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Volumn 118, Issue 38, 1996, Pages 9204-9205

Predicting antibody catalyst selectivity from optimum binding of catalytic groups to a hapten

Author keywords

[No Author keywords available]

Indexed keywords

FURAN DERIVATIVE; PYRAN DERIVATIVE;

EID: 0029827813     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja961353u     Document Type: Article
Times cited : (36)

References (25)
  • 8
    • 0027922032 scopus 로고
    • and references therein
    • (b) Danishefsky, S. Science 1993, 259, 469 and references therein,
    • (1993) Science , vol.259 , pp. 469
    • Danishefsky, S.1
  • 20
    • 10244220140 scopus 로고    scopus 로고
    • note
    • The theoretical catalyst, or theoretical enzyme, has been nicknamed a "theozyme".
  • 21
    • 10244278268 scopus 로고    scopus 로고
    • note
    • Calculations on both five-membered complexes for more than 200 optcycles produce the complexes shown. After the first 100 steps, the optimizations showed an oscillating pattern between optcycles, but no real change in structure or energy occurs. Both six-membered complexes are energy-minimized structures.
  • 23
    • 10244239611 scopus 로고    scopus 로고
    • note
    • N1 character for the endo opening was found to be true for the cis case also, as well as the cis and trans 4-exo- vs 5-endoepoxide openings.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.