Chronic clozapine versus chronic haloperidol treatment: Differential effects on electrically evoked dopamine efflux in the rat caudate putamen, but not in the nucleus accumbens

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 354, Issue 6, 1996, Pages 725-730

  Feasey Truger, Karin J ^a   Alzheimer, Christian ^a   Ten Bruggencate, Gerrit ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

Caudate putamen; Chronic treatment; Clozapine; Dopamine; Haloperidol; In vivo fast cyclic voltammetry; Nucleus accumbens; Rat

Indexed keywords

CLOZAPINE; HALOPERIDOL; NEUROLEPTIC AGENT;

ANIMAL EXPERIMENT; ARTICLE; BRAIN REGION; CONTROLLED STUDY; CYCLIC POTENTIOMETRY; DOPAMINE RELEASE; ELECTROSTIMULATION; MALE; NONHUMAN; NUCLEUS ACCUMBENS; ORAL DRUG ADMINISTRATION; PUTAMEN; RAT;

EID: 0029827810     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF00166898     Document Type: Article

References (43)

1. Armstrong-James M, Millar J (1979) Carbon fibre microelectrodes. J Neurosci Methods 1:279-287
2. Blaha CD, Lane RF (1987) Chronic treatment with classical and atypical antipsychotic drugs differentially decreases dopamine release in striatum and nucleus accumbens in vivo. Neurosci Lett 78:199-204
3. Bunney BS, Grace AA (1978) Acute and chronic haloperidol treatment: Comparison of effects on nigral dopaminergic cell activity. Life Sci 23:1715-1728
4. Chai B, Meltzer HY (1992) The effect of chronic clozapine on basal dopamine release and apomorphine-induced DA release in the striatum and nucleus accumbens as measured by in vivo brain microdialysis. Neurosci Lett 136:47-50
5. Chen J, Paredes W, Gardner EL (1991) Chronic treatment with dozapine selectively decreases basal dopamine release in nucleus accumbens but not in caudate-putamen as measured by in vivo brain microdialysis: further evidence for depolarization block. Neurosci Lett 122:127-131
6. Chesi AJR, Feasey-Truger KJ, Alzheimer C, ten Bruggencate G (1995) Dopamine autoreceptor sensitivity is unchanged in rat nucleus accumbens after chronic haloperidol treatment: an in vivo and in vitro voltammetric study. Eur J Neurosci 7:2450-2457
7. Chiodo LA, Bunney BS (1983) Typical and atypical neuroleptics: differential effects of chronic administration on the activity of A9 and AlO midbrain dopaminergic neurons. J Neurosci 3:1607-1619
8. Chiodo LA, Bunney BS (1985) Possible mechanisms by which repeated clozapine administration differentially affects the activity of two subpopulations of midbrain dopamine neurons. J Neurosci 5: 2539-2544
9. 2 receptor occupancy in patients treated with classical neuroleptics and clozapine. Relation to extrapyramidal side-effects. Arch Gen Psychiatry 49:538-544
10. Feasey-Truger KJ, Earl CD, Alzheimer C, ten Bruggencate G (1995a) Stimulus-evoked dopamine overflow in the rat nucleus accumbens is decreased following chronic haloperidol administration: an in vivo voltammetric study. Neurosci Lett 183:91-95
11. Feasey-Truger KJ, Alzheimer C, ten Bruggencate G (1995b) Chronic clozapine administration reduces stimulus-evoked dopamine overflow in the rat nucleus accumhens in vivo. Soc Neurosci. Abstr. 21, 1139
12. Grace AA, Bunney BS (1986) Induction of depolarization block in midbrain dopamine neurons by repeated administration of haloperidol: analysis using in vivo intracellular recording. J Pharmacol Exp Ther 238:1092-1100
13. Hernandez L, Hoebel BG (1989) Haloperidol given chronically decreases basal dopamine in the prefrontal cortex more than the striatum or nucleus aecumbens as simultaneously measured by microdialysis. Brain Res Bull 22:763-769
14. Hernandez L, Hoebel BG (1995) Chronic clozapine selectively decreases prefrontal cortex dopamine as shown by simultaneous cortical, aecumbens, and striatal microdialysis in freely moving rats. Pharmacol Biochem Behav 52:581-589
15. Ichikawa J, Meltzer HY (1990) Apomorphine does not reverse reduced basal dopamine release in rat striatum and nucleus accumbens after chronic haloperidol treatment. Brain Res 507:138-142
16. Ichikawa J, Meltzer HY (1991) Differential effects of repeated treatment with haloperidol and clozapine on dopamine release and metabolism in the striatum and the nucleus aecumbens. J Pharmacol Exp Ther 256:348-357
17. Invernizzi R, Morali F, Pozzi L, Samanin R (1990) Effects of acute and chronic clozapine on dopamine release and metabolism in the striatum and nucleus accumbens of conscious rats. Br J Pharmacol 100:744-748
18. Invernizzi R, Pozzi L, Samanin R (1995) Further studies on the effects of chronic clozapine on regional extracellular dopamine levels in the brain of conscious rats. Brain Res 670:165-168
19. Kuhr WG, Bigelow JC, Wightman RM (1986) In vivo comparison of the regulation of releasable dopamine in the caudate nucleus and the nucleus accumbens of the rat brain. J Neurosci 6:974-982
20. Lane RE, Blaha CD (1987) Chronic haloperidol decreases dopamine release in striatum and nucleus accumbens in vivo: depolarization block as a possible mechanism of action. Brain Res Bull 18:135-138
21. 1-noradrenergic receptors demonstrated by in vivo voltammetry. Brain Res 460:398-401
22. 2 receptor modulation in rat striatum and nucleus accumbens after subchronic and chronic haloperidol treatment. Brain Res 575:47-56
23. Mereu G, Lilliu V, Vargiu P, Muntoni AL, Diana M, Gessa GL (1994) Failure of chronic haloperidol to induce depolarization inactivation of dopamine neurons in unanesthetized rats. Eur J Pharmacol 264:449-453
24. Mereu G, Lilliu V, Vargiu P, Muntoni AL, Diana M, Gessa GL (1995) Depolarization inactivation of dopamine neurons: an artifact? J Neurosci 15:1144-1149
25. Millar J, Stamford JA, Kruk ZL, Wightman RM (1988) Electrochemical, pharmacological and electrophysiological evidence of rapid dopamine release and removal in the rat caudate nucleus following electrical stimulation of the median forebrain bundle. Eur J Pharmacol 109:341-348
26. Moghaddam B, Bunney BS (1993) Depolarization inactivation of dopamine neurons: terminal release characteristics. Synapse 14:195-200
27. Nowak JZ, Arbilla S, Galzin AM, Langer SZ (1983) Changes in sensitivity of release modulating dopamine autoreceptors after chronic treatment with haloperidol. J Parmacol Exp Ther 226: 558-564
28. O'Dell SJ, La Hoste GJ, Widmark CB, Shapiro RM, Potkin SG, Marshall JF (1990) Chronic treatment with clozapine or haloperidol differentially regulates dopamine and serotonin receptors in rat brain. Synapse 6:146-153
29. O'Donnell P, Grace AA (1995) Different effects of subchronic clozapine and haloperidol on dye-coupling between neurons in the rat striatal complex. Neuroscience 66:763-767
30. Onn S-P, Grace AA (1995) Repeated treatment with haloperidol and clozapine exerts differential effects on dye coupling between neurons in subregions of striatum and nucleus accumbens. J Neurosci 15:7024-7036
31. Paxinos G, Watson C (1982) The rat brain in stereotaxic coordinates. Academic Press, New York
32. Reynolds GP (1992) Developments in the drug treatment of schizophrenia. Trends Pharmaeol 13:116-121
33. Rupniak NMJ, Hall MD, Mann S, Fleminger S, Kilpatrick G, Jenner P, Marsden CD (1985) Chronic treatment with clozapine, unlike haloperidol, does not induce changes in striatal D-2 receptor function in the rat. Biochem Pharmacol 34:2755-2763
34. Saller CF, Salania AI (1985) Alterations in dopamine metabolism after chronic administration of haloperidol. Neuropharmacol 24: 123-129
35. Stamford JA, Kruk ZL, Millar J (1988a) Stimulated limbic and striatal dopamine release measured by last cyclic voltammetry: anatomical, electrochemical and pharmacological characterization. Brain Res 454:282-288
36. Stamford JA, Kruk ZL, Millar J (1988b) Actions of dopamine antagonists on stimulated striatal and limbic dopamine release: an in vivo volummetric study. Br J Pharmacol 94:924-932
37. Stamford JA (1989) In vivo voltammetry - prospects for the next decade. Trends Neurosci 12:407-412
38. White FJ, Wang RY (1983) Differential effects of classical and atypical antipsychotic drugs on A9 and A10 dopamine neurons. Science 221:1054-1057
39. Wiedemann DJ, Garris PA, Near JA, Wightman RM (1992) Effect of chronic haloperidol treatment on stimulated synaptic overflow of dopamine in the rat striatum. J Pharm Exp Ther 261:574-579
40. 2) receptors in the rat brain. Brain Res 487:288-298
41. Yamada S, Yokoo H, Nishi S (1993) Chronic treatment with haloperidol modifies the sensitivity of autoreceptors that modulate dopamine release in rat striatum. Eur J Pharmacol 232:1-6
42. Yamamoto BK, Cooperman MA (1994) Differential effects of chronic antipsychotic drug treatment on extracellular glutamate and dopumine concentrations. J Neurosci 14:4159-4166
43. Youngren KD, Moghaddam B, Bunney BS, Roth RH (1994) Preferential activation of dopamine overflow in prefrontal cortex produced by chronic clozapine treatment. Neurosci Lett 165:41-44