Exploration of the possible roles of phospholipase D and protein kinase C in the mechanism of ischemic preconditioning in the myocardium

Annals of the New York Academy of Sciences

Volumn 793, Issue , 1996, Pages 210-225

  Eskildsen Helmond, Yvonne E G ^a   Gho, Ben C G ^a   Bezstarosti, Karel ^a   Dekkers, Dick H W ^a   Soei, Loe Kie ^a   Van Heugten, Han A A ^a   Verdouw, Pieter D ^a   Lamers, Jos M J ^a  

^a ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE; PHOSPHOLIPASE D; POLYMYXIN B; PROTEIN KINASE C; SERINE; THREONINE;

CONFERENCE PAPER; ENZYME ACTIVATION; HEART INFARCTION; HEART LEFT VENTRICLE; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HYDROLYSIS; NONHUMAN; POTASSIUM CURRENT; PROTEIN EXPRESSION; PROTEIN TRANSPORT; SECOND MESSENGER;

EID: 0029827427     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1996.tb33516.x     Document Type: Conference Paper

References (79)

1. DOWNEY, J. M. 1992. Ischemic preconditioning: nature's own cardioprotective intervention. Trends Cardiovasc. Med. 2: 170-176.
2. MURRY, C. E. & R. B. JENNINGS. 1986. Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation 74: 1124-1136.
3. LIU, Y. & J. M. DOWNEY. 1992. Ischemic preconditioning protects against infarction in rat heart. Am. J. Physiol. 263: H1107-H1112.
4. LI, G. C., J. A. VASQUEZ, K. P. GALLAGHER & B. R. LUCCHESI. 1990. Myocardial protection with preconditioning. Circulation 82: 609-619.
5. URABE, K., T. M. MIURA, T. I. IWAMOTO, T. OGAWA, M. GOTO, J. SAKAMOTO & O. IIMURA. 1993. Preconditioning enhances myocardial resistance to post-ischaemic myocardial stunning via adenosine receptor activation. Cardiovasc. Res. 27: 657-662.
6. SCHOTT, R. J., S. ROHMAN, E. R. BRAUN & W. SCHAPER. 1990. Ischemic preconditioning reduces infarct size in swine myocardium. Circ. Res. 66: 1122-1142.
7. KONING, M. M. G., L. A. J. SIMONIS, S. DE ZEEUW, S. NIEUKOOP, S. POST & P. D. VERDOUW. 1994. Ischaemic preconditioning by partial occlusion without intermittent reperfusion. Cardiovasc. Res. 28: 1146-1151.
8. KLONER, R. A. & D. YELLON. 1994. Does ischemic preconditioning occur in patients? J. Am. Coll. Cardiol. 24: 1133-1142.
9. LAWSON, C. S. 1994. Does ischemic preconditioning occur in the human heart? Cardiovasc. Res. 28: 1461-1466.
10. VERDOUW, P. D., B. C. G. GHO & D. J. DUNCKER. 1995. Ischaemic preconditioning: is it clinically relevant? Eur. Heart J. 16: 1169-1176.
11. SHIKI, K. & D. J. HEARSE. 1987. Preconditioning of ischemic myocardium: reperfusion-induced arrhythmias. Am. J. Physiol. 253: H1470-H1476.
12. VEGH, A., S. KOHMARI, L. SZEKERES & J. R. PARRATT. 1992. Antiarrhythmic effects of preconditioning in anaesthetized dogs and rats. Cardiovasc. Res. 26: 487-495.
13. LAWSON, C. S. & J. M. DOWNEY. 1993. Preconditioning: state of the art myocardial protection. Cardiovasc. Res. 27: 542-550.
14. LI, Y., P. WHITTAKER & R. A. KLONER. 1992. The transient nature of the effect of ischemic preconditioning on myocardial infarct size and ventricular arrhythmia. Am. Heart J. 123: 346-353.
15. KLONER, R. A., K. PRZYKLENK, P. WHITTAKER & S. HALE. 1995. Editorial. Preconditioning stimuli and inadvertent preconditioning. J. Mol Cell. Cardiol. 27: 743-747.
16. 1 adenosine receptors in rabbit heart. Circulation 84: 350-356.
17. GROSS, G. J. & J. A. AUCHAMPACH. 1992. Blockade of ATP-sensitive potassium channels prevents myocardial preconditioning in dogs. Circ. Res. 70: 223-233.
18. BANERJEE, A., C. LOCKE-WINTER, K. B. ROGERS, M. B. MITCHELL, E. C. BREW, C. B. CAIRNS, D. D. BENSARD & A. H. HARKEN. 1993. Preconditioning against myocardial dysfunction after ischemia and reperfusion by an α-adrenergic mechanism. Circ. Res. 73: 656-670.
19. 1-Adrenergic agonists precondition rabbit ischemic myocardium independent of adenosine by direct activation of protein kinase C. Circ. Res. 75: 576-585.
20. THORNTON, J. D., G. S. LIU & J. M. DOWNEY. 1993. Pretreatment with pertussis toxin blocks the protective effects of preconditioning: evidence for a G-protein mechanism. J. Mol. Cell. Cardiol. 25: 311-320.
21. YAO, Z. & G. J. GROSS. 1993. Acetylcholine mimics ischemic preconditioning via a glibencamide-sensitive mechanism in dogs. Am. J. Physiol. 264: H2221-H2225.
22. PARRATT, J. R. 1994. Protection of the heart by ischemic preconditioning mechanisms and possibilities for pharmacological exploitation. Trends Pharmacol. Sci. 15: 19-25.
23. GOTO, M., Y. LIU, X-M. YANG, J. L. ARDELL, M. V. COHEN & J. M. DOWNEY. 1995. Role of bradykinin in protection of ischemic preconditioning in rabbit heart. Circ. Res. 77: 611-621.
24. LIU, Y., A. TSUCHIDA, M. V. COHEN & J. M. DOWNEY. 1995. Pretreatment with angiotensin II activates protein kinase C and limits myocardial infarction in isolated rabbit hearts. J. Mol. Cell. Cardiol. 27: 883-892.
25. 2 phenylisopropyl-adenosine (PIA) acts as a therapeutic preconditioning-mimetic agent in rabbits. Cardiovasc. Res. 27: 2140-2145.
26. TOOMBS, C. F., D. S. MCGAE, W. E. JOHNSON & J. VINTON-JOHANSON. 1992. Myocardial protective effects of adenosine: infarct size reduction with pretreatment and continued receptor stimulation during ischemia. Circulation 86: 986-994.
27. YTREHUS, K., Y. LIU & J. M. DOWNEY. 1993. Preconditioning protect the ischemic rabbit heart by protein kinase C activation. Am. J. Physiol. 266: H1145-H1152.
28. SPEECHLY-DICK, M. E., M. M. MOCANU & D. M. YELLON. 1994. Protein kinase C. Its role in ischemic preconditioning in the rat. Circ. Res. 75: 586-590.
29. MITCHELL, M. B., X. MENG, L. AO, J. M. BROWN, A. H. HARKEN & A. BANERJEE. 1995. Preconditioning of isolated rat heart is mediated by protein kinase C. Circ. Res. 76: 73-81.
30. DE JONGE, H. W., H. A. A. VAN HEUGTEN & J. M. J. LAMERS. 1995. Review. Signal transduction by the phosphatidylinositol cycle in myocardium. J. Mol. Cell. Cardiol. 27: 93-106.
31. + channel? Studies of the contractile function after simulated ischemia in an atrial in vivo model. Circ. Res. 77: 1030-1035.
32. LIU, G. S., W. D. GAO, B. O'ROURKE & E. MARBAN. 1995. Synergistic potentiation of ATP-sensitive potassium current by protein kinase C and adenosine: implications for ischemic preconditioning. Circulation 92: I-251.
33. HU, K., D. DUAN & S. NATTEL. 1995. Protein kinase C-mediated activation of ATP-sensitive potassium current - the missing link in ischemic preconditioning. Circulation 92(Suppl. I): I-251.
34. LINDMAR, R., K. LÖFFELHOLZ & J. SANDMAN. 1988. On the mechanism of muscarinic hydrolysis of choline phospholipids. Biochem. Pharmacol. 37: 4689-4695.
35. KURZ, T. & R. A. WOLF. 1993. Phosphatidic acid stimulates inositol 1,4,5-triphosphate production in adult cardiac myocytes. Circ. Res. 72: 701-706.
36. SADOSHIMA, J. & S. IZUMO. 1993. Signal transduction pathways of angiotensin II induced c-fos gene expression in cardiac myocytes in vitro. Circ. Res. 73: 424-438.
37. LAMERS, J. M. J., H. W. DE JONGE, V. PANAGIA & H. A. A. VAN HEUGTEN. 1993. Receptor mediated signalling pathways acting through membrane phospholipid hydrolysis in cardiomyocytes. Cardioscience 4: 121-131.
38. LAMERS, J. M. J., Y. E. G. ESKILDSEN-HELMOND, A. M. RESINK, H. W. DE JONGE, K. BEZSTAROSTI, H. S. SHARMA, H. A. A. VAN HEUGTEN. 1995. Endothelin-1-induced phospholipase C-β and D and protein kinase C isoenzyme signalling leading to hypertrophy in rat cardiomyocytes. J. Cardiovasc. Pharmacol. 26(Suppl. 3): S100-S103.
39. ESKILDSEN-HELMOND, Y. E. G., H. A. A. VAN HEUGTEN & J. M. J. LAMERS. 1996. Regulation and functional significance of phospholipase D in myocardium. Mol. Cell. Biochem. In press.
40. MORARU, I. I., L. M. POPESCU, N. MAULIK, X. LIU & D. K. DAS. 1992. Phospholipase D signalling in ischemic heart. Biochim. Biophys. Acta 1139: 148-154.
41. PRZYKLENK, K., M. A. SUSSMAN, B. Z. SIMKHOVICH & R. A. KLONER. 1995. Does ischemic preconditioning trigger translocation of protein kinase C in the canine model. Circulation 92: 1546-1557.
42. BUGGE, E. & K. YTREHUS. 1995. Ischemic preconditioning is protein kinase C dependent but not through stimulation of α-adrenergic or adenosine receptors in the isolated rat heart. Cardiovasc. Res. 29: 401-406.
43. LIU, Y., K. YTREHUS & J. M. DOWNEY. 1994. Evidence that translocation of protein kinase C is a key event during ischemic preconditioning of rabbit myocardium. J. Mol. Cell. Cardiol. 26: 661-668.
44. LIU, Y., M. V. COHEN & J. M. DOWNEY. 1994. Chelerythrine, a highly selective protein kinase C inhibitor, blocks the anti-infarct effect of ischemic preconditioning in rabbit hearts. Cardiovasc. Drugs Ther. 8: 881-882.
45. LI, Y. & R. A. KLONER. 1995. Does protein kinase C play a role in ischemic preconditioning in rat hearts? Am. J. Physiol. 268: H426-H431.
46. ARMSTRONG, S., J. M. DOWNEY & C. E. GANOTE. 1994. Preconditioning of isolated rabbit cardiomyocytes: induction by metabolic stress and blockade by the adenosine antagonist SPT and calphostin C, a protein kinase C inhibitor. Cardiovasc. Res. 28: 72-77.
47. TAMAOKI, T. 1991. Use and the specificity of staurosporine, UCN-01, and calphostin C as protein kinase inhibitors. Methods Enzymol. 201: 340-347.
48. HERBERT, J. M., J. M. AUGEREAU, J. GLEYE & J. P. MAFFRAND. 1990. Chelerythrine is a potent and specific inhibitor of protein kinase C. Biochem. Biophys. Res. Commun. 172: 993-999.
49. KOBAYASHI, E., H. NAKANO, M. MORIMOTO & T. TAMAOKI. 1989. Calphostin C (UCN-1028C), a novel microbial compound, is a highly potent and specific inhibitor of protein kinase C. Biochem. Biophys. Res. Commun. 159: 548-553.
50. HUG, H. & T. F. SARRE. 1990. Protein kinase C isoenzymes: divergence in signal transduction? Biochem. J. 291: 329-343.
51. NAKAMURA, S. & Y. NISHIZUKA. 1994. Lipid mediators and PKC activation for the intracellular signalling network. J. Biochem. 115: 1029-1034.
52. STEINBERG, S. F., M. GOLDBERG & V. O. RYBIN. 1995. Protein kinase C isoform diversity in the heart. J. Mol. Cell. Cardiol. 27: 141-153.
53. HARRINGTON, E. O. & J. A. WARE. 1995. Diversity of the protein kinase C gene family. Implications for cardiovascular disease. Trends Cardiovasc. Med. 5: 193-198.
54. ALLEN, B. G. & S. KATZ. 1991. Isolation and characterization of the calcium and phospholipid-dependent protein kinase (protein kinase C) subtypes from bovine heart. Biochemistry 30: 4334-4343.
55. RYBIN, V. O. & S. F. STEINBERG. 1994. Protein kinase C isoform expression and regulation in the developing heart. Circ. Res. 74: 299-309.
56. MOCHLY-ROSEN, D., C. J. HEINRICH, L. CHEEVER, H. KHANER & P. C. SIMPSON. 1990. A protein kinase C isoenzyme is translocated to cytoskeletal elements on activation. Cell Regul. 1: 693-706.
57. WEINBRENNER, C. E., G. SIMONIS, R. MARQUETANT & R. H. STRASSER. 1993. Selective regulation of calcium-dependent and calcium-independent subtypes of protein kinase C in acute and prolonged myocardial ischemia. Circulation 88(Suppl. 1): I-101.
58. BOGOYEVITCH, M. A., P. J. PARKER & P. H. SUGDEN. 1993. Characterization of protein kinase C isotype expression in adult rat heart. Circ. Res. 72: 757-767.
59. VOGT, A., M. BARANCIK, D. WEIHRAUCH, M. ARRAS, T. PODZUWEIT & W. SCHAPER. 1994. Protein kinase C inhibitors reduce infarct size in pig hearts in vivo. Circulation 90(Suppl. I): I-647.
60. SCHAAP, D. & P. J. PARKER. 1990. Expression, purification, and characterization of protein kinase C-ε. J. Biol. Chem. 265: 7301-7307.
61. CLERK, A., M. A. BOGOYEVITSCH, M. B. ANDERSON & P. SUGDEN. 1994. Differential activation of protein kinase C isoforms by endothelin-1, and phenylephrine and subsequent stimulation of p42 and p44 mitogen-activated protein kinases in ventricular myocytes cultured from neonatal rat hearts. J. Biol. Chem. 269: 32848-32857.
62. LINDMAR, R., K. LÖFFELHOLZ & J. SANDMANN. 1988. On the mechanism of muscarinic hydrolysis of choline phospholipids. Biochem. Pharmacol. 37: 4689-4695.
63. PANAGIA, V., C. OU, Y. TAIRA, J. DAI & N. S. DHALLA. 1991. Phospholipase D activity in subcellular membranes of rat ventricular myocardium. Biochim. Biophys. Acta 1064(2): 242-250.
64. TAKI, T. & J. N. KANFER. 1981. Phospholipase D from rat brain. Methods Enzymol. 71: 746-750.
65. SADOSHIMA, J. & S. IZUMO. 1993. Signal transduction pathways of angiotensin II-induced c-fos gene expression in cardiac myocytes in vitro. Circ. Res. 73: 424-438.
66. HONGPING, Y., R. A. WOLF, T. KURZ & P. B. CORR. 1994. Phosphatidic acid increases in response to noradrenaline and endothelin-1 in adult rabbit ventricular myocytes. Cardiovasc. Res. 28: 18128-18134.
67. KURZ, T., R. A. WOLF & P. B. CORR. 1993. Phosphatidic acid stimulates inositol 1,4,5-triphosphate production in adult cardiac myocytes. Circ. Res. 72: 701-706.
68. BERRIDGE, M. J. 1987. Inositol trisphosphate and diacylglycerol: two interacting second messengers. Annu. Rev. Biochem. 56: 159-193.
69. THOMPSON, N. T., R. W. BONSER & L. G. GARLAND. 1991. Receptor-coupled phospholipase D and its inhibition. Trends Pharmacol. Sci. 12: 404-408.
70. 1-adrenergic agonist- and ET-1 evoked phosphoinositide cycle responses in cultured neonatal rat cardiomyocytes. Biochem. Biophys. Res. Commun. 203: 422-429.
71. PESSIN, M. S. & D. M. RABEN. 1989. Molecular species analysis of 1,2-diglycerides stimulated by α-thrombin in cultured fibroblasts. J. Biol. Chem. 264: 8729-8738.
72. LEE, M. W. & D. L. SEVERSON. 1994. Signal transduction in vascular smooth muscle: diacylglycerol messengers and PKC action. Am. J. Physiol. 267: C659-C678.
73. VAN HEUGTEN, H. A. A., H. W. DE JONGE, K. BEZSTAROSTI, H. S. SHARMA, P. D. VERDOUW & J. M. J. LAMERS. 1995. Intracellular signalling and genetic reprogramming during agonist-induced hypertrophy of cardiomyocytes. Ann. N. Y. Acad. Sci. 752: 343-352.
74. 1-adrenergic stimulated phosphatidylinositol cycle in cultured rat cardiomyocytes. J. Mol. Cell. Cardiol. 26: 1081-1093.
75. VAN HEUGTEN, H. A. A., K. BEZSTAROSTI, D. H. W. DEKKERS & J. M. J. LAMERS. 1993. Homologous desensitization of the endothelin-1 receptor mediated phosphoinositide response in cultured neonatal rat cardiomyocytes. J. Mol. Cell. Cardiol. 25: 41-52.
76. THOMPSON, N. T., K. G. GARLAND & R. W. BONSER. 1993. Phospholipase D: regulation and functional significance. Adv. Pharmacol. 24: 199-238.
77. CLERK, A., M. A. BOGOYEVITCH, M. B. ANDERSSON & P. SUGDEN. 1994. Differential activation of protein kinase C isoforms by endothelin-1 and phenylephrine and subsequent stimulation of p42 and p44 mitogen-activated protein kinases in ventricular myocytes cultured from neonatal rat hearts. J. Biol. Chem. 269: 32848-32857.
78. BRUNNER, F. 1995. Tissue endothelin-l levels in perfused rat heart following stimulation with agonists and in ischaemia and reperfusion. J. Mol. Cell. Cardiol. 27: 1953-1963.
79. LISCOVITCH, M., P. BEN-AV, M. DANIN, G. FAIMAN, H. ELDAR & E. LIVNEH. 1993. Phosphatidylcholine: a role in cell signalling. J. Lipid Mediators 8: 177-182.