Sepsis increases endocytosis of endotoxin into hepatocytes

Surgery

Volumn 120, Issue 2, 1996, Pages 389-394

  Ghermay, A P ^a   Brady, S ^a   Havel, R J ^a   Harris, H W ^a   Rapp, J H ^a  

^a SAN FRANCISCO GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHYLOMICRON; ENDOTOXIN; LIPOPOLYSACCHARIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENDOCYTOSIS; ENDOSOME; HYPERTRIGLYCERIDEMIA; LIVER CELL; NONHUMAN; PRIORITY JOURNAL; RAT; SEPSIS;

EID: 0029827161     PISSN: 00396060     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0039-6060(96)80314-X     Document Type: Article

References (20)

1. Flegel WA Wolpl D Mannel DN Northoff H Inhibition of endotoxin-induced activation of human monocytes by human lipoproteins Infect Immun 57 1989 2237 2245
2. Cavaillon JM Fitting C Cavaillon NH Warren H Cytokine response by monocytes and macrophages to free and lipoprotein bound lipopolysaccharide Infect Immun 58 1990 2375 2382
3. Harris HW Grunfeld C Feingold KR Read TE Kane JP Rapp JH Chylomicrons alter the fate of endotoxin, decreasing tumor necrosis factor release and preventing death J Clin Invest 91 1993 1028 1034
4. Read TE Harris HW Grunfeld C Feingold KR Kane JP Rapp JH Chylomicrons enhance endotoxin excretion in bile Infect Immun 61 1993 3496 3502
5. Read TE Grunfeld C Feingold KR Calhoun MC Kumwenda Z Rapp JH Triglyceride-rich lipoproteins prevent septic death in rats J Exp Med 182 1995 267 272
6. Windler E Greeve J Daerr W Greten H Binding of rat chylomicrons and their remnants to the hepatic low-density-lipoprotein receptor and its role in remnant removal Biochem J 252 1988 553 561
7. Choi SY Cooper AD A comparison of the roles of the low density lipoprotein (LDL) receptor and the LDL receptor-related protein/alpha 2 macroglobulin receptor in chylomicron remnant removal in the mouse in vivo J Biol Chem 268 1993 15804 15811
8. Willnow TE Goldstein SL Orth K Brown MS Herz J Low density lipoprotein receptor-related protein and gp 330 bind similar ligands, including plasminogen activator-inhibitor complexes and lactoferrin an inhibitor of chylomicron remnant clearance J Biol Chem 267 1992 26172 26180
9. Yen FT Mann CJ Lydie MG Identification of a lipolysis-stimulated receptor that is distinct from the LDL receptor and the LDL receptor-related protein Biochemistry 33 1994 1172 1180
10. Herz J Qui S Oesterle A Desilva HV Shafi S Havel RJ Initial hepatic removal of chylomicron remnants is unaffected but endocytosis is delayed in mice lacking the low density lipoprotein receptor Proc Natl Acad Sci 92 1995 4611 4615
11. Levin J Tomasulo PA Oser RS Detection of endotoxin in human blood and demonstration of an inhibitor J Lab Clin Med 75 1970 903 911
12. Uleveitch RJ The preparation and characterization of radioiodinated bacterial lipopolysaccharide Immunochemistry 15 1978 157 164
13. Belcher JD Hamilton RL Brady SE Isolation and characterization of three endosomal fractions from the liver of estradiol-treated rats Proc Natl Acad Sci 84 1987 6785 6789
14. Havel RJ Chylomicron remnants: hepatic receptors and metabolism Curr Opin Lipidol 6 1995 312 316
15. Mokuno H Brady S Kotite L Herz J Havel R Effect of 39 K-da receptor-associated protein on the hepatic uptake and endocytosis of chylomicron remnants and low density lipoproteins in rats J Biol Chem 269 1994 13238 13243
16. Jackson RL Busch SJ Cardin AD Glycosaminoglycans: molecular properties, protein interactions, and role in physiological processes Physiol Rev 71 1991 481 539
17. Shafi S Brady SE Bensadoun S Havel RJ Role of hepatic lipase in the uptake of chylomicron remnants in rat liver J Lipid Res 35 1994 709 719
18. Obayashi T Addition of perchloric acid to blood samples for colorimetric limulus test using chromogenic substrate: comparison with conventional procedures and clinical applications J Lab Clin Med 104 1984 321 330
19. Harris HW Eichbaum EB Kane JP Rapp JH Detection of endotoxin in triglyceride-rich lipoproteins in vitro J Lab Clin Med 118 1991 186 193
20. Eichbaum EB Harris HW Kane JP Rapp JH Chylomicrons can inhibit endotoxin activity in vitro J Surg Res 51 1991 413 416