Direct effects of ethanol on signaling proteins

Alcoholism: Clinical and Experimental Research

Volumn 20, Issue 8 SUPPL., 1996, Pages

  Charness, Michael E ^a  

^a VA BOSTON HEALTHCARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; CYCLIC AMP DEPENDENT PROTEIN KINASE; NERVE CELL ADHESION MOLECULE; POTASSIUM CHANNEL;

ALCOHOL CONSUMPTION; ALCOHOLISM; CHANNEL GATING; CONFERENCE PAPER; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

EID: 0029826622     PISSN: 01456008     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1530-0277.1996.tb01767.x     Document Type: Conference Paper

References (35)

1. Deitrich RA, Dunwiddie TV, Harris RA, Erwin VG: Mechanism of action of ethanol: initial central nervous system actions. Pharmacol Rev 41:489-537, 1989
2. Weight FF: Cellular and molecular physiology of alcohol actions in the nervous system. Int Rev Neurobiol 33:289-348, 1992
3. Franks NP, Lieb WR: Molecular mechanisms of general anesthesia. Nature 300:487-493, 1982
4. Wood WG, Schroeder F, Rao AM: Significance of ethanol-induced changes in membrane lipid domains. Alcohol Alcohol (Suppl) 1:221-225, 1991
5. Avdulov NA, Wood WG, Harris RA: Effects of ethanol on structural parameters of rat brain membranes: relationship to genetic differences in ethanol sensitivity. Alcohol Clin Exp Res 18:53-59, 1994
6. Schroeder F, Colles SM, Kreishman GP, Heyliger CE, Wood WG: Synaptic plasma membrane structure and polarity of long-sleep and short-sleep mice. Arch Biochem Biophys 309:369-376, 1994
7. Franks NP, Lieb WR: Do general anaesthetics act by competitive binding to specific receptors? Nature 310:599-601, 1984
8. Peoples RW, Weight FF: Cutoff in potency implicates alcohol inhibition ot N-methyl-D-aspartate receptors in alcohol intoxication, Proc Natl Acad Sci USA 92:2825-2829, 1995
9. Li C, Peoples RW, Weight FF: Alcohol action on a neuronal membrane receptor: Evidence for a direct interaction with the receptor protein. Proc Natl Acad Sci USA 91:8200-8204, 1994
10. 3 receptor-activated current. Soc Neurosci 20:1127, 1994 (abstr)
11. Slater SJ, Cox KJ, Lombardi JV, Ho C, Kelly MB, Rubin E, Stubbs CD: Inhibition of protein kinase C by alcohols and anaesthetics. Nature 364:82-84, 1993
12. Wong EV, Kenwrick S, Willems P, Lemmon V: Mutations in the cell adhesion molecule L1 cause mental retardation. Trends Neurosci 18:168-172, 1995
13. Zhao X, Siu C-H: Colocalization of the homophilic binding site and the neuritogenic activity of the cell adhesion molecule L1 to its second Ig-like domain. J Biol Chem 270:29413-29421, 1995
14. Wong EV, Cheng G, Payne HR, Lemmon V: The cytoplasmic domain of the cell adhesion molecule L1 is not required for homophilic adhesion. Neurosci Lett 200:155-158, 1995
15. Doherty P, Williams E, Walsh FS: A soluble chimeric form of the L1 glycoprotein stimulates neunte outgrowth. Neuron 14:57-66, 1995
16. Ignelzi M, Jr., Miller DR, Soriano P, Maness PF: Impaired neurite outgrowth of src-minus cerebellar neurons on the cell adhesion molecule L1. Neuron 12:873-884, 1994
17. Charness ME, Safran RM, Perides G: Ethanol inhibits neural cell-cell adhesion. J Biol Chem 269:9304-9309, 1994
18. Ramanathan R, Wilkemeyer MF, Mittal B, Perides G, Charness ME: Ethanol inhibits cell-cell adhesion mediated by human L1. J Cell Biol 133:381-390, 1996
19. McCreery MJ, Hunt WA: Physico-chemical correlates of alcohol intoxication. Neuropharmacology 17:451-461, 1978
20. Lyon RC, McComb JA, Schreurs J, Goldstein DB: A relationship between alcohol intoxication and the disordering of brain membranes by a series of short-chain alcohols. J Pharmacol Exp Ther 218:669-675, 1981
21. Akinshola BE, Weight FF: Aliphatic N-alcohols exhibit a cutoff in potency for the inhibition of recombinant GLUR3 receptor subunit current in Xenopus oocytes. Soc Neurosci Abstr 21:1815, 1995
22. Peoples RW, Weight FF: Aliphatic alcohols exhibit a cutoff in potency for enhancement of GABA-activated ion current. Soc Neurosci 21:1814, 1995 (abstr)
23. Yu D, Zhang L, Weight FF: Ethanol inhibits recombinant α 7 nicotinic acetylcholine receptor mediated current in Xenopus oocytes. Soc Neurosci 21:1814, 1995 (abstr)
24. Zhang L, Yu DH, Changeux J-P, Weight FF: N-terminal domain mediates alcohol action on a neurotransmitter receptor. Alcohol Clin Exp Res (suppl) 20: 9A, 1996 (abstr)
25. Covarrubias M, Rubin E: Ethanol selectively blocks a nonactivating K+ current expressed in Xenopus oocytes. Proc Natl Acad Sci USA 90:6957-6960, 1993
26. Anantharam V, Bayley H, Wilson A, Treistman SN: Differential effects of ethanol on electrical properties of various potassium channels expressed in oocytes. Mol. Pharmacol 42:499-505, 1992
27. Covarrubias M, Vyas TB, Escobar L, Wei A: Alcohols inhibit a cloned potassium channel at a discrete saturable site. Insights into the molecular basis of general anesthesia. J Biol Chem 270:19408-19416, 1995
28. Gordon AS, Sapru MK, Krauss SW, Diamond I: Nucleoside transport and ethanol-induced heterologous desensitization. in Ailing C, Diamond I, Leslie SW et al.(eds): Alcohol, Cell Membranes, and Signal Transduction in Brain. New York, Plenum Press, 1993, pp 195-203
29. Rius RA, Govoni S, Battaini F, Trabucchi M: Cyclic AMP-dependent protein phosphorylation is reduced in rat striatum after chronic ethanol treatment. Brain Res 365:355-359, 1986
30. Coe IR, Dohrman DP, Constantinescu A, Diamond I, Gordon AS: Activation of cyclic AMP-dependent protein kinase reverses tolerance of a nucleoside transporter to ethanol. J Pharmacol Exp Ther 276:365-369, 1996
31. Mochly-Rosen D: Localization of protein kinases by anchoring proteins: a theme in signal transduction. Science 268:247-251, 1995
32. Bacskai BJ, Hochner B, Mahaut-Smith M, Adams SR, Kaang BK, Kandel ER, Tsien RY: Spatially resolved dynamics of cAMP and protein kinase A subunits in Aplysia sensory neurons. Science 260:222-226, 1993
33. Wilke N, Sganga M, Barhite S, Miles MF: Effects of alcohol on gene expression in neural cells, in Jansson B, Jörnvall H, Rydberg-U et al. (eds): Toward a Molecular Basis of Alcohol Use and Abuse. Basel, Birkhaüser Verlag, 1994, pp49-54
34. Sapru MK, Diamond I, Gordon AS: Adenosine receptors mediate cellular adaption to ethanol in NG108-15 cells. J Pharmacol Exp Ther 271:542-548, 1994
35. Avdulov NA, Chochina S, Daragan VA, Schroeder F, Mayo KH, Wood WG: Direct binding of ethanol to bovine serum albumin: A fluorescent and 13C NMR multiplet study. Biochem 35:340-347, 1996