Local extravascular growth factor delivery in myocardial ischemia

Drug Delivery: Journal of Delivery and Targeting of Therapeutic Agents

Volumn 3, Issue 3, 1996, Pages 143-147

  Lopez, John J ^b   Simons, Michael ^a  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b NONE

Author keywords

angiogenesis; collateral circulation; growth factors

Indexed keywords

ANGIOGENIC FACTOR; FIBROBLAST GROWTH FACTOR; GROWTH FACTOR; MICROSPHERE; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL MODEL; COLLATERAL CIRCULATION; CONFERENCE PAPER; CORONARY ARTERY BLOOD FLOW; DRUG DELIVERY SYSTEM; HEART MUSCLE ISCHEMIA; MICROVASCULATURE; MINIPUMP; NONHUMAN; OSMOTIC MINIPUMP; PHARMACEUTICS; PRIORITY JOURNAL; SWINE;

EID: 0029825728     PISSN: 10717544     EISSN: None     Source Type: Journal    
DOI: 10.3109/10717549609029443     Document Type: Conference Paper

References (29)

1. Folkman, J., and Klagsbrun, M. (1987) Angiogenic factors. Science 235, 442-447.
2. Yanagisawa-Miwa, A., Uchida, Y., Nakamura, F., Tomaru, T., Kido, H., Kamijo, T., Sugimoto, T., Kaji, K., Utsuyama, M., Kurashima, C., and Ito, H. (1992) Salvage of infarct myocardium by angiogenic action of basic fibroblast growth factor. Science 257, 1401-1403.
3. Battler, A., Scheinowitz, M., Bor, A., Hasdai, D., Bered, Z., Di Segni, E., Varda-Bloom, N., Nass, D., Engelberg, S., Eldar, M., Belkin, M., and Savion, N. (1993) Intracoronary injection of basic fibroblast growth factor enhances angiogenesis in infarcted swine myocardium. J. Am. Coll. Cardiol. 22, 2001-2006.
4. Harada, K., Grossman, W., Friedman, M., Edelman, E. R., Prasad, P., Manning, W. J., Sellke, F. W., and Simons, M. (1994) Basic fibroblast growth factor improves myocardial function in chronically ischemic porcine hearts. J. Clin. Invest. 94, 623-630.
5. Unger, E., Banai, S., Shou, M., Lazarous, D., Jaklitsch, M., Scheinowitz, M., Correa, R., Klingbeil, C., and Epstein, S. E. (1994) Basic fibroblast growth factor enhances myocardial collateral flow in a canine model. Am. J. Physiol. 266, H1588-H1595.
6. Lazarous, D. F., Scheinowitz, M., Shou, M., Hodge, E., Rajanayagam, M. A., Hunsberger, S., Robison, W. G., Jr., Stiber, J. A., Correa, R., Epstein, S. E., and Unger, E. F. (1995) Effects of chronic systemic administration of basic fibroblast growth factor on collateral development in the canine heart. Circulation 91, 145-153.
7. Baffour, R., Berman, J., Garb, J. L., Rhee, S. W., Kaufman, J., and Friedman, P. (1992) Enhanced angiogenesis and growth of collaterals by in vivo administration of recombinant basic fibroblast growth factor in a rabbit model of acute lower limb ischemia: dose response effect of basic fibroblast growth factor. J. Vasc. Surg. 16, 181-191.
8. Asahara, T., Bauters, C., Zheng, L. P., Takeshita, S., Buntig, S., Ferrara, N., Symes, J. F., and Isner, J. M. (1995) Synergistic effects of VEGF and bFGF on angiogenesis in vivo. Circulation 92(Suppl. II):365-371.
9. Harada, K., Friedman, M., Lopez, J. J., Prasad, P., Hibberd, M., Pearlman, J., Sellke, F., and Simons, M. (1996) VEGF improves coronary flow and myocardial function in chronically ischemic porcine hearts. Am. J. Physiol, 270, H1791-H1802.
10. Banai, S., Jaklitsch, M., Shou, M., Lazarous, D., Scheinowitz, M., Biro, S., Epstein, S., and linger, E. (1994) Angiogenic-induced enhancement of collateral blood flow to ischemic myocardium by vascular endothelial growth factor in dogs. Circulation 89, 2183-2189.
11. Lopez, J., Stamler, A., Edelman, E. R., Hibberd, M., Caputo, R. P., Carrozza, J. P., Prasad, P., Douglas, P., Sellke, F., and Simons, M. (1995) Local bFGF treatment results in angiographic collateral development, dose related increase in coronary flow and myocardial function in chronic myocardial ischemia. Circulation 92(8):1-67. (abstract)
12. Sporn, M. B., and Roberts, A. B. (1988) Peptide growth factors are multifunctional. Nature 332, 217-219.
13. Mazue, G., Bertolero, F., Garofano, L., Brughera, M., and Carminati, P. (1992) Experience with the preclinical assessment of basic fibroblast growth factor (bFGF). Toxicol. Lett. 64/65, 329-338.
14. Mazue, G., Bertolo, F., Jacob, C., Sarmientos, P., and Roncucci, R. (1991) Preclinical and clinical studies with recombinant human basic fibroblast growth factor. Ann. N.Y.Acad. Sci. 638, 329-340.
15. Cuevas, P., Carceller, F., Ortega, S., Zazo, M., Nieto, I., and Gimenez-Gallego, G. (1991) Hypotensive activity of fibroblast growth factor. Science 250, 1208-1210.
16. Ku, D. D., Zaleski, J. K., Kiu, S., and Brock, T. A. (1993) Vascular endothelial growth factor induces EDRF-dependent relaxation in coronary arteries. Am. J. Physiol. 265, H586-H592.
17. Isner, J., Walsh, K., Symes, J., Pieczek, A., Takeshita, S., Lowry, J., Rossow, S., Rosenfield, K., Weir, L., Brogi, E., and Schainfeld, R. (1995) Arterial gene therapy for therapeutic angiogenesis in patients with peripheral artery disease. Circulation 91, 2687-2692.
18. Edelman, E. R., Nugent, M. A., and Karnovsky, M. J. (1993) Perivascular and intravenous administration of basic fibroblast growth factor: vascular and solid organ deposition. Proc. Natl. Acad. Sci. USA 90, 1513-1517.
19. Whalen, G. F., Shing, Y., and Folkman, J. (1989) The fate of intravenously administered bFGF and the effect of heparin. Growth Factors 1, 157-164.
20. Hondermarck, H., Courty, J., Boilly, B., and Thomas, D. (1990) Distribution of intravenously administered acidic and basic fibroblast growth factors in the mouse. Experientia 46, 973-974.
21. White, F. C., Carroll, S. M., Magnet, A., and Bloor, C. M. (1992) Coronary collateral development in swine after coronary artery occlusion. Circ. Res. 71, 1490-1500.
22. Roth, D. M., Maruoka, Y., Rogers, J., White, R. C., Longhurst, J. C., and Bloor, C. M. (1987) Development of coronary collateral circulation in left circumflex ameroid-occluded swine myocardium. Am. J. Physiol. 253, H1279-H1288.
23. Gorge, G., Schmidt, T., Ito, B. R., Pantely, G. A., and Schaper, W. (1989) Microvascular and collateral adaptation in swine hearts following progressive coronary artery stenosis. Basic Res. Cardiol. 84, 524-535.
24. Sharma, H. S., and Schaper, W. (1993) The role of growth factors during development of a collateral circulation in the porcine heart. In: Collateral Circulation Heart, Brain, Kidney, Limbs (Schaper, W., and Schaper, J., eds.), pp. 123-149, Kluwer Academic, Boston.
25. Edelman, E. R., Nugent, M. A., Smith, L. T., and Karnovsky, M. J. (1992) Basic fibroblast growth factor enhances the coupling of intimal hyperplasia and proliferation of vasa vasorum in injured rat arteries. J. Clin. Invest. 89, 465-473.
26. Schaper, W., Gorge, G., Winkler, B., and Schaper, J. (1988) The collateral circulation of the heart. Prog. Cardiovasc. Dis. 31, 57-77.
27. Fujita, M., Sasayama, Ohno, A., Nakajima, H., and Asanoi, H. (1987) Importance of angina for the development of collateral circulation. Br. Heart J. 57, 139-143.
28. Hirai, T., Fujita, M., Nakajima, H., Asanoi, H., Yamamishi, K., Ohno, A., and Sasayama, S. (1989) Importance of collateral circulation for prevention of left ventricular aneurysm formation in acute myocardial infarction. Circulation 79, 791-796.
29. TIMI Study Group. (1988) The thrombolysis in myocardial infarction trial. N. Engl. J. Med. 312, 932-939.