Prostaglandin production via induction of cyclooxygenase-2 by human gingival fibroblasts stimulated with lipopolysaccharides

Inflammation

Volumn 20, Issue 5, 1996, Pages 555-568

  Noguchi, K ^a   Shitashige, M ^a   Yanai, M ^a   Morita, I ^a   Nishihara, T ^b   Murota, S ^a   Ishikawa, I ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; DEXAMETHASONE; GENISTEIN; HERBIMYCIN A; INDOMETACIN; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE;

ACTINOBACILLUS ACTINOMYCETEMCOMITANS; ARTICLE; CELL STIMULATION; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; ENZYME INDUCTION; ESCHERICHIA COLI; FIBROBLAST; GINGIVA; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; PATHOGENESIS; PERIODONTAL DISEASE; PORPHYROMONAS; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION;

ACTINOBACILLUS ACTINOMYCETEMCOMITANS; CELLS, CULTURED; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; DINOPROSTONE; ENZYME INDUCTION; ESCHERICHIA COLI; FIBROBLASTS; GINGIVA; HUMANS; ISOENZYMES; LIPOPOLYSACCHARIDES; MEMBRANE PROTEINS; PERIODONTAL DISEASES; PORPHYROMONAS GINGIVALIS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES;

ACTINOBACILLUS ACTINOMYCETEMCOMITANS; BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; PORPHYROMONAS GINGIVALIS;

EID: 0029825727     PISSN: 03603997     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF01487046     Document Type: Article

References (47)

1. NEEDLEMAN, P., J. TURK, B. A. JAKSCHIK, A. R. MORRISON, and B. LEFKOWITH. 1986. Arachidonic acid metabolism. Ann. Rev. Biochem. 55:69-102.
2. 2 secretion as a determination of periodontal disease expression. J. Periodontol. 64:432-444.
3. OHM, K., VON H-K. ALBERS, and B. P. LISBOA. 1984. Measurement of 8 prostaglandins in human gingival and periodontal disease using high pressure liquid chromatography and radioimmunoassay. J. Periodont. Res. 19:235-249.
4. OFFENBACHER, S., B. M. ODLE, and T. E. VAN DYKE. 1984. The use of crevicular fluid prostaglandin E levels as a measure of the periodontal disease status of adult and juvenile periodontitis patients. J. Periodont. Res. 19:1-13.
5. 2 levels as a predictor of periodontal attachment loss. J. Periodont. Res. 21:101-112.
6. KLEIN, D. C., and L. G. RAISZ. 1970. Prostaglandins: stimulation of bone resorption in tissue culture. Endocrinology 86:1436-1440.
7. 2 stimulated bone resorption. Lab. Invest. 42:290-295.
8. WAITE, I. M., C. A. SAXON, A. YOUNG, B. J. WAGG, and M. CORBETT. 1981. The periodontal status of subjects receiving non-steroidal anti-inflammatory drugs. J. Periodont. Res. 16:100-108.
9. WILLIAMS, R. C., M. K. JEFFOCAT, T. H. HOWELL, A. ROLLA, D. STUBBS, K. W. TEOH, M. S. REDDY, and P. GOLDHABER. 1989. Altering the progression of human alveolar bone loss with the non-steroidal anti-inflammatory drug flurbiprofen. 60:485-490.
10. PAGELS, W. R., R. J. SACHS, L. S. MARNETT, D. L. DEWITT, J. S. DAY, and W. L. SMITH. 1983. Immunochemical evidence for the involvement of prostaglandin H synthase in hydroperoxide-dependent oxidations by ram seminal microsomes. J. Biol. Chem. 258:6517-6525.
11. MIYAMOTO, T., N. OGINO, S. YAMAMOTO, and O. HAYAISHI. 1976. Purification of prostaglandin endoperoxide synthase from bovine vesicular gland microsomes. J. Biol. Chem. 251:2629-2636.
12. KREAMER, S. A., E. A. MEADA, and D. L. DEWITT. 1992. Prostaglandin endoperoxide synthase gene structure: Identification of the transcriptional start site and 5′-flanking regulatory sequences. Arch. Biochem. Biophy. 293:391-400.
13. KUJUBU, D. A., and H. R. HERSHMAN. 1992. Dexamethasone inhibits mitogen induction of the TIS10 prostaglandin synthase/cyclooxygenase/cyclooxygenase gene. J. Biol. Chem. 267:7991-7994.
14. O'NEILL, G. P., and A. W. FORD-HUTCHINSON. 1993. Expression of mRNA for cyclooxygenase-1 and cyclooxygenase-2 in human tissues. 330:156-160.
15. HLA, T., and K. NEILSON. 1992. Human cyclooxygenase-2 cDNA. Proc. Natl. Acad. Sci. U.S.A. 89:7384-7388.
16. JONES, D. A., D. P. CARLTON, T. M. MCINTYRE, G. A. ZIMMERMAN, and S. M. PRESCOTT. 1993. Molecular cloning of human prostaglandin endoperoxide synthase type II and demonstration of expression in response to cytokines. J. Biol. Chem. 268:9049-9054.
17. LEE, S. H., E. SOYOOLA, P. CHANMUGAM, S. HART, W. SUN, H. ZHONG, S. LIOU, D. SIMMON, and D. HWANG. 1992. Selective expression of mitogen-inducible cyclooxygenase in macrophages stimulated with lipopolysaccharide. J. Biol. Chem. 267:25934-25938.
18. MAIER, J. A. M., T. HLA, and T. MACING. 1990. Cyclooxygenase is an immediate-early gene induced by interleukin-1 in human endothclial cells. J. Biol. Chem. 265:10805-10808.
19. SIMON, B. I., H. M. GOLDMAN, M. P. RUBEN, and E. BAKER. 1970. The role of endotoxin in periodontal disease II. Correlation of the quantity of endotoxin in human gingival exudate with the clinical degree of inflammation. J. Periodont. 41:81-86.
20. SIMON, B. I., H. M. GOLDMAN, M. P. RUBEN, and E. BAKER. 1971. The role of endotoxin in periodontal disease. 3. Correlation of the amount of endotoxin in human gingival exudate with the histologic degree of inflammation. J. Periodontol. 42:210-216.
21. SCHWARTZ, J., F. STINSON, and R. PARKER. 1972. The passage of tritiated bacterial endotoxin across intact gingival crevicular epithelium. J. Periodontol. 43:270-279.
22. ZAMBON, J. J., L. A. CHRISTERSSON, and J. SLOTS. 1983. Actinobacillus actinomycetemcomitans in human periodontal disease: prevalence in patient groups and distribution of biotypes and serotypes within families. J. Periodontol. 54:707-711.
23. DZINK, J. L., A. C. TANNER, A. D. HAFFAJEE, and S. S. SOCRANSKY. 1985. Gram negative species associated with active destructive periodontitis lesions. J. Clin. Periodontol. 12:648-659.
24. 2 synthesis in human gingival fibroblasts through a primary effect on circulating mononuclear cells. Infect. Immun. 55:2148-2154.
25. 3 and interleukin-1β release from rat peritoneal and human gingival fibroblasts in vitro. Oral Microbiol. Immunol. 6:378-380.
26. WESTPHAL, O., and K. JANN. 1965. Bacterial lipopolysaccharides. Extraction with phenolwater and further applications of the procedure. In Methods Carbohydrate Chemistry. R. Whistler, J. Demiller, and E. Wolfrom, editors, Academic Press, New York, pp. 83-91.
27. KOGA, T., T. NISHIHARA, T. FUJIWARA, T. NISHIZUKA, N. OKAHASHI, T. NOGUCHI, and S. HAMADA. 1985. Biochemical and immunological properties of lipopolysaccharide (LPS) from Bacteroides gingivalis and comparison with LPS from Escherichia coli. Infect. Immun. 47:638-647.
28. NISHIHARA, T., T. FUJIWARA, T. KOGA, and S. HAMADA. 1986. Chemical and composition and immunological properties of lipopolysaccharide and lipid-associated proteoglycan from Actinobacillus actinomycetemcomitans. J. Periodont. Res. 21:521-530.
29. MORITA, I., M. SCHINDLER, M. K. REGIER, J. C. OTTO, T. HORI, D. L. DEWITT, and W. L. SMITH. 1995. Differential intracellular locations for prostaglandin endoperoxide H synthase-1 and -2. J. Biol. Chem. 270:10902-10908.
30. MORITA, I., W. L. SMITH, D. L. DEWITT, and M. SCHINDLER. 1995. Expression-activity profiles of cells transfected with prostaglandin endoperoxide H synthase measured by quantitative fluorescence microscopy. Biochemistry. 34:7194-7199.
31. FUTAKI, N., S. TAKAHASHI, M. YOKOYAMA, I. ARAI, S. HIGUCHI, and S. OTOMO. 1994. New anti-inflammatory agent, selectively inhibits prostaglandin G/H synthase/cyclooxygenase (COX-2) activity in vitro. Prostaglandins 47:55-59.
32. 2 in mouse bone marrow-derived mast cells. J. Biol. Chem. 269:22269-22275.
33. O'BANION, M. K., V. D. WINN, and D. A. YOUNG. 1992. cDNA cloning and functional activity of a glucocorticoid-regulated inflammatory cyclooxygenase. Proc. Natl. Acad. Sci. U.S.A. 89:4888-4892.
34. MASFERRER, J. L., S. T. REDDY, B. S. ZWEIFEL, K. SEIBERT, P. NEEDLEMAN, R. S. GILBERT, and H. R. HERSHMAN. 1994. In vivo glucocorticoids regulate cyclooxygenase-2 but not cyclooxygenase-1 in peritoneal macrophages. J. Pharmacol. Experiment. Therapeutics. 270:1340-1344.
35. RICHARDS, D., and B. RUTHERFORD. 1988. The effects of interleukin 1 on collagenolytic activity and prostaglandin-E secretion by human periodontal-ligament and gingival fibroblast. Archs. Oral Biol. 33:237-243.
36. NOVOTNY, A. 1984. Heterogeneity of endotoxin. In Handbook of Endotoxins. Vol. 1. E. T. Reitschel, editors, Elsevier Science Publishers, Amsterdam, p. 308.
37. HEMPEL, S. L., H. MARTHA, M. MONICK, and G. W. HUNNINGHAKE. 1994. Lipopolysaccharide induces prostaglandin H synthase-2 protein and mRNA in human alveolar macrophages and blood monocytes. J. Clin. Invest. 93:391-396.
38. CHANMUOAM, P., L. FENG, S. LIOU, B. C. JANG, M. BOUDREAU, G. YU, J. H. LEE, H. J. KWON, T. BEPPU, M. YOSHIDA, Y. XIAS, CV. B. WILSON, and D. HWANG. 1995. Radicicol, a protein tyrosine kinase inhibitor, suppresses the expression of mitogen-inducible cyclooxygenase in macrophages stimulated with lipopolysaccharide and in experimental glomerulonephritis. J. Biol. Chem. 270:5418-5426.
39. FENG, L., Y. XIA, G. E. GARCIA, D. HWANG, and C. B. WILSON. 1995. Involvement of reactive oxygen intermediates in cycloxygenase-2 expression induced by interleukin-1, tumor necrosis factor-alpha, and lipopolysaccharide. J. Clin. Invest. 95:1669-1675.
40. UEHARA, Y., and H. FUKAZAWA. 1991. Use and selectivity of herbimycin A as inhibitor of protein-tyrosine kinases. Meth. Enzymol. 201:370-379.
41. GRABER, M., C. H. JUNE, L. E. SAMELSON, and A. WEISS. 1992. The protein tyrosine kinase inhibitor herbimycin A, but not genistein, specifically inhibits signal transduction by the T cell antigen receptor. Int. Immunol. 4:1201-1210.
42. AKIYAMA, T., J. ISHIDA, S. NAKAGAWA, H. OGAWARA, S. WATANABE, N. ITOH, M. SHIBUYA, and Y. FUKAMI. 1987. Genistein, a specific inhibitor of tyrosine-specific protein kinases. J. Biol. Chem. 262:5592-5595.
43. TAKADA, H., J. MIHARA, I. MORISAKI, and S. HAMADA. 1991. Induction of interleukin-1 and -6 in human gingival fibroblast cultures stimulated with Bacteroides lipopolysaccharides. 59:295-301.
44. NEWTON, R. C., and M. COVINGTIN. 1987. The activation of human fibroblast prostaglandin E production by interleukin 1. Cellular Immunology 110:338-349.
45. NOGUCHI, K., M. YANAI, and I. ISHIKAWA. Prostaglandin production via cyclooxygenase-2 by human gingival fibroblasts. J. Dent. Res. (special issue); 419.
46. MASFERRER, J. L., B. S. ZWEIFEL, P. T. MANNING, S. D. HAUSER, K. M. LEAHY, W. G., SMITH, P. C. ISAKSON, and K. SEIBERT. 1994. Selective inhibition of inducible cyclooxygenase-2 in vivo is antiinflammatory and nonulcerogenic. Proc. Natl. Acad. Sci. U.S.A. 91:3228-3232.
47. SEIBERT, K., Y. ZHANG, K. LEAHY, S. HAUSER, J. MASFERRER, W. PERKINS, L. LEE, and P. ISAKSON. 1994. Pharmacological and biochemical demonstration of the role of cyclooxygenase in inflammation and pain. Proc. Natl. Acad. Sci. U.S.A. 91:12013-12017.