Detection of exogenous DNA in blastocysts after continuous exposure to DNA carrier sperm

Journal of Assisted Reproduction and Genetics

Volumn 13, Issue 7, 1996, Pages 602-605

  Chan, Philip J ^a,b   King, Alan ^a   Kalugdan, Theresa ^a   Cabrera, Milagros ^a   Seraj, Ibrahim M ^a  

^a LOMA LINDA UNIVERSITY   (United States)

^b Department of Physiology and Pharmacology ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA FRAGMENT;

ARTICLE; BLASTOCYST; DNA DETERMINATION; EMBRYO DEVELOPMENT; ENZYME ACTIVITY; FERTILIZATION IN VITRO; HUMAN; HUMAN CELL; ISOTOPE LABELING; PREIMPLANTATION EMBRYO; PRIORITY JOURNAL; SEMEN ANALYSIS; SPERMATOZOON;

EID: 0029825060     PISSN: 10580468     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02066616     Document Type: Article

References (7)

1. Chan PJ, Kalugdan T, Su BC, Whitney EA, Perrott W, Tredway DR, King A: Sperm as a noninvasive gene delivery system for preimplantation embryos. Fertil Steril 1995;63:1121-1124
2. Camaioni A, Russo MA, Odorisio T, Gandolfi F, Fazio, VM, Siracusa G: Uptake of exogenous DNA by mammalian spermatozoa: Specific localization of DNA on sperm heads. J Reprod Fert 1992;96:203-212
3. Francolini M, Lavitrano M, Lamia CL, French D, Frati L, Cotelli F, Spadafora C: Evidence for nuclear internalization of exogenous DNA into mammalian sperm cells. Mol Reprod Dev 1993;34:139
4. Barbosa M, Schlegel R: The E6 and E7 genes of HPV 18 are sufficient for inducing two stage in vitro transformation of human keratinocytes. Oncogene 1989;4:1529-1532
5. Snow MHL, McLaren A: The effect of exogenous DNA upon cleaving mouse embryos. Exp Cell Res 1974;86:1-8
6. Brackett BG, Baranska W, Sawicki W, Koprowsky H: Uptake of heterologous genome by mammalian sprematozoa and its transfer to ova through fertilization. Proc Natl Acad Sci USA 1971;68:353-357
7. Ng SC, Sathananthan AH, Bongso TA, Ratnam SS, Tok VCN, Ho JKC: Subzonal transfer of multiple sperm (MIST) into early human embryos. Mol Reprod Dev 1990;26:253-260