Radiosensitivity of human breast cancer cell lines of different hormonal responsiveness. Modulatory effects of oestradiol

International Journal of Radiation Biology

Volumn 70, Issue 2, 1996, Pages 161-169

  Villalobos, M ^a   Becerra, D ^a   Nunez M I ^a   Valenzuela, M T ^a   Siles, E ^a   Olea, N ^a   Pedraza, V ^a   Ruiz De Almodovar J M ^a  

^a HOSPITAL UNIVERSITARIO VIRGEN DE LAS NIEVES   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ESTRADIOL;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CONTROLLED STUDY; DNA STRAND BREAKAGE; FEMALE; HORMONE RESPONSE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; RADIOSENSITIVITY;

BREAST NEOPLASMS; CELL CYCLE; CELL SURVIVAL; DNA DAMAGE; ESTRADIOL; FEMALE; HUMANS; RADIATION TOLERANCE; TUMOR CELLS, CULTURED;

EID: 0029824327     PISSN: 09553002     EISSN: None     Source Type: Journal    
DOI: 10.1080/095530096145157     Document Type: Article

References (42)

1. BARTEK, J., IGGO, R., GANNON, J., and LANE, D. P., 1990. Genetic and immunochemical analysis of mutant p53 in human breast cancer cell lines. Oncogene, 10, 893-899.
2. BOHR, V. A., PHILLIPS, D. H., and HANAWALI, P. C., 1987, Heterogeneous DNA damage and repair in the mammalian genoma. Cancer Research, 47, 6426-6436.
3. CHIU, S. M., OLFINICK, N. L., FRIEDMAN, L. R., and STAMBROOK, J. P., 1982. Hypersensitivity of DNA in transcriptionally active chromatin to ionizing radiation. Biochimica et Biophysica Acta, 699, 15-21.
4. DEL MORAL, R., FERNANDEZ, J. C., LOPEZ-GONZALEZ, J. D., GOMEZ, M., RUTZ DE ALMODOVAR, J. M., OLEA, N., and PEDRAZA, V., 1991, Kinetics of cellular proliferation and hormonal receptors in EVSA-T breast cancer cell line. Revist Española de Fisiología, 7, 25-30.
5. ELLA, M. C., and BRADLEY, M. O., 1992, Influence of chromatin structure on the induction of DNA double strand breaks by ionizing radiation, Cancer Research, 52, 1580-1586.
6. HAIMOVTTZ-FRIEDMAN, A., VLODAVSKY, I., CHAUDHURI, A., WITTE, L., AND FUKS, Z., 1991, Autocrine effects of fibroblast growth factor in repair of radiation damage in endothelial cells. Cancer Research, 51, 2552-2558.
7. IHAKIS, G. F.., METZGER, L., DENKO, N., and STAMATO, T. D., 1991, Detection of DNA double-strand breaks in synchronous cultures of CHO cells by means of asymmetric field inversion gel electrophoresis. International Journal of Radiation Biology, 59, 321-341.
8. KEYDAR, I., CHEN, L., KARBY, S., WEISS, F. R., DELAREA, J., RADU, M., CHAITCIK, S. and BRENNER, H. J., 1979, Establishment and characterization of a cell line of human breast carcinoma origin. European Journal of Cancer, 15, 659-670.
9. KWOK, T. T., and SUTHERLAND, R. M., 1989, Enhancement of sensitivity of human squamous carcinoma cells to radiation by epidermal growth factor. Journal of the National Cancer Institute, 81, 1020-1024.
10. LIPPMAN, M., BOLAN, G., and HUFF, K., 1976, The effects of estrogen and antiestrogens on hormone-responsive human breast cancer in long-term tissue culture. Cancer Research, 36, 4595-4601.
11. LOTTERING, M. L., HAAG, M., and SEEGERS, J., 1992, Effects of 17β-estradiol metabolites on cell cycle events in MCF-7 cells. Cancer Research, 52, 5926-5932.
12. MCILWRATH, A. J., VASEY, P. A., ROSS, G. M., and BROWN, R., 1994, Cell cycle arrests and radiosensitivity of human tumor cell lines: Dependence on wild-type p53 for radiosensitivity. Cancer Research, 54, 3718-3722.
13. NUÑEZ, M. I., VILLALOBOS, M., OLEA, N., VALENZUELA, M. T., PEDRAZA, V., MCMILLAN, T. J., and RUTZ DE ALMODÓVAR, J. M., 1995, Radiation-induced DNA double-strand break rejoining in human tumour cells. British Journal of Cancer, 71, 311-316.
14. OKAYASU, R., BLÓVHER, D. M., and ILIAKIS, G. F., 1988, Variation through the cell cycle of DNA neutral filter elution dose response in X-irradiated synchronous CHO-cells. Internationl Journal of Radiation Biology, 53, 729-747.
15. OLEA, N., VILLALOBOS, M., RUTZ, DE ALMODÓVAR, J. M., and PEDRAZA, V., 1992, MCF-7 Breast cancel cells grown as multicellular spheroids in vitro: effects of 17β estradiol. International Journal of Cancer, 50, 112-117.
16. OLEA, N., VILLALOBOS, M., THOMAS, J., LOPEZ GONZALEZ, J. D., RUTZ DE ALMODÓVAR, J. M., and PEDRAZA, V., 1987, Cinética de proliferación en cultivos celulares MCF-7. II. Sincronización y reclutamiento celular hormonalmente-inducidos. Revista Española de Fisiología, 43, 215-222.
17. OLIVE, P. L., 1992, DNA organization affects radiosensitivity and detection of initial DNA strand breaks. International Journal of Radiation Biology, 62, 389-396.
18. OLIVE, P. L., WLODEKD, C., and BANATH, J. P., 1991, DNA double strand breaks measured in individual cells subjected to gel electrophoresis. Cancer Research, 51, 4671-4676.
19. OSBORM, C. K., BOLDI, D., and ESTRADA, P., 1984, Human breast cancer cell cycle synchronization by estrogens and anti-estrogens in culture. Cancer Research, 43, 1433-1439.
20. PEACOCK, J. H., EADY, J. J., EDWARDS, S. M., MCMILLAN, T. J., and STEEL, G. G., 1992, The intrinsic α/β ratio for tumour cells: is it a constant? International Journal of Radiation Biology, 61, 479-487.
21. PEACOCK, J. H., RUTZ, DE ALMODÓVAR, J. M., MCMILLLAN, T. J., and STEEL, G. G., 1993, The nature of the initial slope of radiation cell survival curves. British Journal of Radiology. Suppl. 24, 57-60.
22. ROBINSON, J. P., 1993, Measurements of DNA. In: Handbook of Flow Cytometry Methods. Edited by: J. P. Robinson, Z. Darzynkiewicz, P. Dean, L. Dressler, H. Tanke and L. Wheeles (Wiley-Liss, New York), pp. 90-126.
23. RUTZ DE ALMODÓVAR, J. M., BUSH, C., PEACOCK J. H., STEEL, G. G., WHITAKER, S. J., and MCMILLAN, T. J., 1994a, Dose-Rate effect for DNA damage induced by ionizing radiation in human tumor cells. Radiation Research, 138, S93-S96.
24. RUTZ DE ALMODÓVAR, J. M., MCMILLAN, T. J., OLEA, N., PEACOCK, J. H., PEDRAZA, Y., STEEL, G. G., VILLALOBOS, M., and WHITAKER, S. J., 1993, Aspectos moleculares, celulares y multicelulares de la radiosensibilidad, In: Avances de la Investigación Oncológica Española. Edited by: J. C. Lacal and M. Barbacid. (Farmiindustria, serie científica. Madrid), pp. 187-226.
25. RUTZ DE ALMODÓVAR, J. M., NUÑEZ, M. I., MCMILLAN, T. J., OLEA, N., MORI, N., VILLALOBOS, M., PEDRAZA, V., and STEEL, G. G., 1994c, Initial radiation-induced DNA damage in human tumour cell lines: a correlation with intrinsic cellular radiosensitivity, British Journal of Cancer, 69, 457-462.
26. RUTZ DE ALMODÓVAR, J. M., STEEL, G. G., WHITAKER, S. J., and MCMILLAN, T. J., 1994b, A comparison of methods for calculating DNA double-strand break induction frequency in mammalian cells by pulsed-gel electrophoresis. International Journal of Radiation Biology, 65, 641-649.
27. SARKARIA, J. N., GIBSON, D. F. C., JORDAN, V. C., FOWLER, J. F., LIDSTRIM, M. J., and MULCAHY, R. T., 1993, Tamoxifen-induced increase in the potential doubling time (Tpot) of MCF-7 xenografts as determined by bromodeoxyuridine labelling and flow cytometry. Cancer Research, 53, 4413-4417.
28. SARKARIA, J. N., MILLER, E. M., PARKER, C. J., JORDAN, V. C., and MULCAHY, R. T., 1994, 4-Hydroxytamoxifen, an active-metabolite of tamoxifen, does not alter the radiation sensitivity of MCF-7 breast carcinoma cells irradiated in vitro. Breast Cancer Research and Treatment. 30, 159-165.
29. SILES, E., VILLALOBOS, M., VALENZUELA, M. T., NUÑEZ, M. I., GORDON, A., MCMILLAN, T. J., PEDRAZA, V., and RUTZ DE ALMODÓVAR, J. M., 1996, Relationship between p53 status and radiosensitivity in human tumour cell lines, 73, 581-588.
30. SOTO, A. M., and SONNENSCHEIN, C., 1985, The role of estrogens on the proliferation of human breast tumor cells (MCF-7). Journal of Steroid Biochemistry. 23, 87-94.
31. SOULE, H. D., VAZQUEZ, J., LONG, A., ALBERI, S., and BRENNAN, M. J., 1973, A human cell line from a pleural effusion derived from a breast carcinoma. Journal of the National Cancer Institute, 51, 1409-1413.
32. SWEIGERT, A., ROWLEY, A., WARTERS, R., and DETHLEFSEN, L., 1988, Cell cycle effect on the induction of DNA double strand breaks by X-ray. Radiation Research, 121, 196-205.
33. TAKAHASHI, K., and SUZUKI, K., 1993, Association of insulin-like growth-factor-I-induced DNA synthesis with phosphorylation and nuclear exclusion of p53 in human breast cancer MCF-7 cells. International Journal of Cancer, 55, 453-458.
34. VAN DER MEER, Y., HUISKAMP, R., DAVIDS, J. A. G., VAN DER TWEEL, I., and DE ROOIJ, D. G., 1992, The sensitivity of quiescent and proliferating mouse spermatogonial stem cells to X irradiation. Radiation Research, 130, 289-295.
35. VILLALOBOS, M., ARANDA, M., NUÑEZ, M. I., BECFRRA, D., OLEA, N., RUTZ DE ALMODÓVAR, J. M., and PEDRAZA, Y., 1995a, Interaction between ionizing radiation, estrogens and antiestrogens in the modification of tumor microenvironment in estrogen dependent multicellular spheroids. Acta Oncologica, 34, 413-417.
36. VILLALOBOS, M., OLEA, N., BROTONS, J. A., OLEA-SERRANO, M. F., RUTZ DE ALMODÓVAR, J. M., and PEDRAZA, V., 1995b, The E-SCREEN assay: Comparison between different MCF7 cell stocks. Environ Health Perspectives, 103, 844-850.
37. VILLALOBOS, M., OLEA, N., GORGOJO, L., LOPEZ-GONZALEZ, J. G., RUTZ DE ALMODÓVAR, J. M., and PEDRAZA, V., 1987, Cinética de proliferación en cultivos celulares MCF-7. I. Influencia relativa de los estrógenos antiestrógenos sobre el crecimiento de la población celular. Revista Española de Fisiología, 43, 209-214.
38. WARD, J. F., 1990, The yield of DNA double strand breaks produced intracellularly by ionizing radiation: a review, 1990. International Journal of Radiation Biology, 44, 75-85.
39. WAZER, D. E., JOYCE, M., CHAN, W., GEWITZ, D., PECK-SUN, L., SOLARE, G., and SCHMIDT-ULRICH, R. K., 1993, Effects of Tamoxifen on the radiosensitivity of hormonally responsive and unresponsive breast carcinoma cells. Radiation Oncology Investigations, 1, 20-28.
40. WAZER, D. E., TERCILLA, O. F., LIN, P. S., and SCHMIDT-ULRICH, R. K., 1989, Modulation in the radiosensitivity of MCF-7 human breast carcinoma cells by 17.3 estradiol and tamoxifen. British Journal of Radiology, 62, 1009-1013.
41. WHEELER, K. T., NELSON, G. B., TERRELL, K. F., and WALLEN, C. A., 1988, Regulation of DNA repair kinetics in proliferative and quiescent tumor cells. International Journal of Radiation Biology, 54, 245-255.
42. WHITAKER, S. J., UNG, Y., and MCMILLAN, T. J., 1995, DNA double strand break induction and rejoining as determinant of human tumor cell radiosensitivity. A pulsed gel electrophoresis study. International Journal of Radiation Biology, 67, 7-18.