Metabolism and toxicity of coumarin on cultured human, rat, mouse and rabbit hepatocytes

Fundamental and Clinical Pharmacology

Volumn 10, Issue 6, 1996, Pages 504-510

  Ratanasavanh, D ^a   Lamiable, D ^b   Biour, M ^c   Guedes Y ^a   Gersberg, M ^d   Leutenegger, E ^d   Riche C ^a  

^a BREST UNIVERSITY HOSPITAL   (France)

^b HÔPITAL MAISON BLANCHE   (France)

^c SORBONNE UNIVERSITÉ   (France)

^d Metabolism Therapeutic Division   (France)

Author keywords

Coumarin; Hepatocyte culture; Metabolism; Toxicity

Indexed keywords

2 HYDROXYPHENYLACETIC ACID; 4 HYDROXYCOUMARIN; COUMARIN; COUMARIN DERIVATIVE; DRUG METABOLITE; LACTATE DEHYDROGENASE; ORTHO COUMARIC ACID; PROADIFEN; UMBELLIFERONE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CULTURE; CYTOTOXICITY; DRUG METABOLISM; DRUG TOXICITY; ENZYME ACTIVITY; HUMAN; LIVER CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; RABBIT; RAT;

EID: 0029824041     PISSN: 07673981     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1472-8206.1996.tb00607.x     Document Type: Article

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