Elements in the murine c-mos messenger RNA 5'-untranslated region repress translation of downstream coding sequences

Cell Growth and Differentiation

Volumn 7, Issue 10, 1996, Pages 1415-1424

  Steel, Laura F ^a   Telly, Diane L ^b   Leonard, Jackie ^a   Rice, Bobbie A ^b   Monks, Bob ^b   Sawicki, Janet A ^b  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b LANKENAU INSTITUTE FOR MEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; MESSENGER RNA;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CELL STRAIN 3T3; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION REGULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTO ONCOGENE; TRANSGENE; TRANSLATION REGULATION;

ANIMALS; CELL LINE; GENES, MOS; MALE; MICE; MOLECULAR SEQUENCE DATA; PROTEIN BIOSYNTHESIS; RNA, MESSENGER; TESTIS;

ANIMALIA; ESCHERICHIA COLI; MURINAE; MUS MUSCULUS;

EID: 0029823747     PISSN: 10449523     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (50)

1. mos. Virology, 143: 321-333, 1985.
2. Yew, N., Strobel, M., and Vande Woude, G. F. Mos and the cell cycle: the molecular basis of the transformed phenotype. Curr. Opin. Genet. Dev., 3: 19-25, 1993.
3. Propst, F., Rosenberg, M. P., Iyer, A., Kaul, K., and Vande Woude, G. F. c-mos proto-oncogene RNA transcripts in mouse tissues: structural features, developmental regulation, and localization in specific cell types. Mol. Cell. Biol., 7: 1629-1637, 1987.
4. Mutter, G. L., and Wolgemuth, D. J. Distinct developmental patterns of c-mos protooncogene expression in female and male mouse germ cells. Proc. Natl. Acad. Sci. USA, 84: 5301-5305, 1987.
5. Goldman, D. S., Kiessling, A. A., Millette, C. F., and Cooper, G. M. Expression of c-mos RNA in germ cells of male and female mice. Proc. Natl. Acad. Sci. USA, 84: 4509-4513, 1987.
6. Colledge, W. H., Carlton, M. B. L., Udy, G. B., and Evans, M. J. Disruption of c-mos causes parthenogenetic development of unfertilized mouse eggs. Nature (Lond.), 370: 65-67, 1994.
7. Hashimoto, N., Watanabe, N., Furuta, Y., Tamemoto, H., Sagata, N., Yokoyama, M., Okazaki, K., Nagayoshi, M., Takeda, N., Ikawa, Y., and Aizawa, S. Parthenogenetic activation of oocytes in c-mos-deficient mice. Nature (Lond.), 370: 68-71, 1994.
8. Papkoff, J., Verma, I. M., and Hunter, T. Detection of a transforming gene product in cells transformed by Moloney murine sarcoma virus. Cell, 29: 417-426, 1982.
9. Blair, D. G., Oakarsson, M., Wood, T. G., McClements, W. L., Fischinger, P. J., and Vande Woude, G. G. Activation of the transforming potential of a normal cell sequence: a molecular model for oncogenesis. Science (Washington DC), 212: 941-943, 1981.
10. Rosenberg, M. P., Aversa, C. R., Wallace, R., and Propst, F. Expression of the c-mos oncogene in male meiotic germ cells of transgenic mice results in metaphase arrest. Cell Growth & Differ., 6: 325-336, 1995.
11. Mutter, G. L., Grills, G. S., and Wolgemuth, D. J. Evidence for the involvement of the proto-oncogene c-mos in mammalian meiotic maturation and possibly very early embryogenesis. EMBO J., 7: 683-689, 1988.
12. Sagata, N., Oskarsson, M., Copeland, T., Brumbaugh, J., and Vande Woude, G. F. Function of c-mos proto-oncogene product in meiotic maturation in Xenopus oocytes. Nature (Lond.), 335: 519-525, 1988.
13. Gebauer, F., Xu, W., Cooper, G. M., and Richter, J. D. Translational control by cytoplasmic polyadenylation of c-mos mRNA is necessary for oocyte maturation in the mouse. EMBO J., 134: 5712-5720, 1994.
14. Sheets, M. D., Fox, C. A., Hunt, T., Vande Woude, G., and Wickens, M. The 3′-untranslated regions of c-mos and cyclin mRNAs stimulate translation by regulating cytoplasmic polyadenylation. Genes Dev., 8: 926-938, 1994.
15. Iwaoki, Y., Matsuda, H., Mutter, G. L., Watrin, F., and Wolgemuth, D. J. Differential expression of the proto-oncogenes c-abl and c-mos in developing mouse germ cells. Exp. Cell Res., 206: 212-219, 1993.
16. Kozak, M. The scanning model for translation: an update. J. Cell Biol., 108: 229-241, 1989.
17. Manzella, J. M., and Blackshear, P. J. Regulation of rat ornithine decarboxylase mRNA translation by its 5′-untranslated region. J. Biol. Chem., 265: 11817-11822, 1990.
18. Rao, C. D., Pech, M., Robbins, K. C., and Aaronson, S. A. The 5′ untranslated sequence of the c-sis/platelet-derived growth factor 2 transcript is a potent translational inhibitor. Mol. Cell. Biol., 8: 284-292, 1988.
19. Ratner, L. Regulation of expression of the c-sis proto-oncogene. Nucleic Acids Res., 17: 4101-4115, 1989.
20. Horvath, P., Suganuma, A., Inaba, M., Pan, Y-B., and Gupta, K. C. Multiple elements in the 5′ untranslated region down-regulate c-sis messenger RNA translation. Cell Growth & Differ., 6: 1103-1110, 1995.
21. Propst, F., and Vande Woude, G. F. Expression of c-mos protooncogene transcripts in mouse tissues. Nature (Lond.), 315: 516-518, 1985.
22. Frohman, M. A., Dush, M. K., and Martin, G. R. Rapid production of full-length cDNAs from rare transcripts: amplification using a single genespecific oligonucteotide primer. Proc. Natl. Acad. Sci. USA, 85: 8998-9002, 1988.
23. Pal, S. K., Zinkel, S. S., Kiessling, A. A., and Cooper, G. M. c-mos expression in mouse oocytes is controlled by initiator-regulated sequences immediately downstream of the transcription initiation site. Mol. Cell. Biol., 11: 5190-5196, 1991.
24. Kozak, M. Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes. Cell, 44: 283-292, 1986.
25. Zuker, M., and Stiegler, P. Optimal folding of large RNA sequences using thermodynamics and auxiliary information. Nucleic Acids Res., 9. 133-148, 1981.
26. Geballe, A. P., and Morris, D. R. Initiation codons within 5′-leaders of mRNAs as regulators of translation. Trends Biochem. Sci., 19: 159-164, 1994.
27. Johansen, H., Schumperli, D., and Rosenberg, M. Affecting gene expression by altering the length and sequence of the 5′ leader. Proc. Natl. Acad. Sci. USA, 81: 7698-7702, 1984.
28. Kozak, M. Selection of initiation sites by eucaryotic ribosomes: effect of inserting AUG triplets upstream from the coding sequence for preproinsulin. Nucleic Acids Res., 12: 3873-3893, 1984.
29. Liu, C-C., Simonsen, C. C., and Levinson, A. D. Initiation of translation at internal AUG codons in mammalian cells. Nature (Lond.), 309: 82-85, 1984.
30. Peabody, D. S., Subramani, S., and Berg, P. Effect of upstream reading frames on translation efficiency in simian virus 40 recombinants. Mol. Cell. Biol., 6: 2704-2711, 1986.
31. Kozak, M. Effects of intercistronic length on the efficiency of reinitiation by eucaryotic ribosomes. Mol. Cell. Biol., 7: 3438-3445, 1987.
32. Miller, P. F., and Hinnebusch, A. G. Sequences that surround the stop codons of upstream open reading frames in GCN4 mRNA determine their distinct functions in translational control. Genes Dev., 3: 1217-1225, 1989.
33. Hill, J. R., and Morris, D. R. Cell-specific translational regulation of S-adenosylmethionine decarboxylase mRNA: dependence on translation and coding capacity of the cis-acting upstream open reading frame. J. Biol. Chem., 268: 726-731, 1993.
34. Degnin, C. R., Schleiss, M. R., Cao, J., and Geballe, A. P. Translational inhibition mediated by a short upstream open reading frame in the human cytomegalovirus gpUL4 (gp48) transcript. J. Virol., 67: 5514-5521, 1993.
35. Kozak, M. An analysis of 5′-noncoding sequences from 699 vertebrate messenger RNAs. Nucleic Acids Res., 15: 8125-8148, 1987.
36. Kozak, M. An analysis of vertebrate mRNA sequences: intimations of translational control. J. Cell Biol., 115: 887-903, 1991.
37. Rechavi, G., Givol, D., and Canaani, E. Activation of a cellular oncogene by DNA rearrangement: possible involvement of an IS-like element. Nature (Lond.), 300: 607-611, 1982.
38. Cohen, J. B., Unger, T., Rechavi, G., Canaani, E., and Givol, D. Rearrangement of the oncogene c-mos in mouse myeloma NSI and hybridomas. Nature (Lond.), 306: 797-799, 1983.
39. Paules, R. S., Propst, F., Dunn, K. J., Blair, D. G., Kaul, K., Palmer, A. E., and Vande Woude, G. F. Primate c-mos proto-oncogene structure and expression: transcription initiation both upstream and within the gene in a tissue-specific manner. Oncogene, 3: 59-68, 1988.
40. Ohuchi, T., Kurita, Y., Sasai, H., Miyoshi, J., Nomura, T., and Kumao, T. Oncogenic activation of murine mos protein kinase by DNA rearrangement of its N-terminal coding region. Oncogene, 7: 331-338, 1992.
41. Marth, J. D., Overell, R. W., Meier, K. E., Krebs, E. G., and Perlmutter, R. M. Translational activation of the Ick proto-oncogene. Nature (Lond.), 332: 171-173, 1988.
42. Bernstein, J., Shefler, I., and Elroy-Stein, O. The translational repression mediated by the platelet-derived growth factor 2/c-sis mRNA leader is relieved during megakaryocytic differentiation. J. Biol. Chem., 270: 10559-10565, 1995.
43. Hill, J. R., and Morris, D. R. Cell-specific translation of S-adenosyl-methionine decarboxylase mRNA: regulation by the 5′ transcript leader. J. Biol. Chem., 267: 21886-21893, 1992.
44. Ruan, H., Hill, J. R., Fatemie-Nainie, S., and Morris, D. R. Cell-specific translational regulation of S-adenosylmethionine decarboxylase mRNA: influence of the structure of the 5′ transcript leader on regulation by the upstream open reading frame. J. Biol. Chem., 269: 17905-17910, 1994.
45. Zimmer, A., Zimmer, A. M., and Reynolds, K. Tissue specific expression of the retinoic acid receptor-β2: regulation by short open reading frames in the 5′-noncoding region. J. Cell Biol., 127: 1111-1119, 1994.
46. Eustice, D. C., Feldman, P. A., Colberg-Poley, A. M., Buckery, R. M., and Neubauer, R. H. A sensitive method for the detection of (3-galactosidase in transfected mammalian cells. Biotechniques, 11: 739-743, 1991.
47. Chirgwin, J. M., Przbyla, A. E., MacDonald, R. J., and Rutter, W. J. Isolation of biologically active ribonucleic acid from sources enriched in ribonuctease. Biochemistry, 18: 5294-5299, 1979.
48. McMaster, G. K., and Carmichael, G. G. Analysis of single- and double-stranded nucleic acids on polyacrylamide and agarose gels by using glyoxal and acridine orange. Proc. Natl. Acad. Sci. USA, 74: 4835-4838, 1977.
49. Hogan, B., Costantini, F., and Lacy, E. Manipulating the Mouse Embryo. Cold Spring Harbor, Cold Spring Harbor Laboratory, 1986.
50. Wood, T. G., McGeady, M. L., Baroudy, B. M., Blair, D. G., and Vande Woude, G. F. Mouse c-mos oncogene activation is prevented by upstream sequences. Proc. Natl. Acad. Sci. USA, 81: 7817-7821, 1984.