Synthesis, molecular modeling, and K+ channel-blocking activity of dequalinium analogues having semirigid linkers

Journal of Medicinal Chemistry

Volumn 39, Issue 21, 1996, Pages 4247-4254

  Rosa, Joaquin Campos ^a,b   Galanakis, Dimitrios ^a,c   Ganellin, C Robin ^a   Dunn, Philip M ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF GRANADA   (Spain)

^c ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

DEQUALINIUM; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT;

AFTERHYPERPOLARIZATION; ANIMAL CELL; ARTICLE; DRUG CONFORMATION; DRUG SYNTHESIS; MOLECULAR MODEL; NONHUMAN; RAT; SYMPATHETIC NERVE CELL;

ANIMALS; CELLS, CULTURED; DEQUALINIUM; MODELS, MOLECULAR; NEURONS; POTASSIUM CHANNELS; RATS; STRUCTURE-ACTIVITY RELATIONSHIP; SUPERIOR CERVICAL GANGLION;

EID: 0029823523     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm950884a     Document Type: Article

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