메뉴 건너뛰기




Volumn 74, Issue 8, 1996, Pages 1263-1268

mdm2 gene mediates the expression of mdr1 gene and P-glycoprotein in a human glioblastoma cell line

Author keywords

Chemotherapy; Glioma; mdm2; mdr1; P glycoprotein

Indexed keywords

ETOPOSIDE; GLYCOPROTEIN P;

EID: 0029823094     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/bjc.1996.527     Document Type: Article
Times cited : (39)

References (42)
  • 2
    • 0027459198 scopus 로고
    • mdm2 expression is induced by wild-type p53 activity
    • BARAK Y, JUVEN T, HAFFNER R AND OREN M. (1993). mdm2 expression is induced by wild-type p53 activity. EMBO J., 12, 461 - 468.
    • (1993) EMBO J. , vol.12 , pp. 461-468
    • Barak, Y.1    Juven, T.2    Haffner, R.3    Oren, M.4
  • 3
    • 0023339504 scopus 로고
    • Molecular analysis and chromosomal mapping of amplified genes isolated from a transformed mouse 3T3 cell line
    • CAHILLY-SNYDER L, YANG-FENG T, FRANCKE U AND GEORGE DL. (1987). Molecular analysis and chromosomal mapping of amplified genes isolated from a transformed mouse 3T3 cell line. Somatic Cell Mol. Genet., 13, 235 - 244.
    • (1987) Somatic Cell Mol. Genet. , vol.13 , pp. 235-244
    • Cahilly-Snyder, L.1    Yang-Feng, T.2    Francke, U.3    George, D.L.4
  • 4
    • 0026017638 scopus 로고
    • Reversal of multidrug resistance
    • CHABNER BA AND WILSON W. (1991). Reversal of multidrug resistance (editorial). J. Clin. Oncol., 9, 4 - 6.
    • (1991) J. Clin. Oncol. , vol.9 , pp. 4-6
    • Chabner, B.A.1    Wilson, W.2
  • 6
    • 0026555717 scopus 로고
    • Modulation of activity of the promoter of the human MDR1 gene by Ras and p53
    • CHIN K-V, UEDA K, PASTAN I AND GOTTESMAN MM. (1992). Modulation of activity of the promoter of the human MDR1 gene by Ras and p53. Science, 255, 459 - 462.
    • (1992) Science , vol.255 , pp. 459-462
    • Chin, K.-V.1    Ueda, K.2    Pastan, I.3    Gottesman, M.M.4
  • 7
    • 0026530432 scopus 로고
    • Clonal p53 mutation in primary cervical cancer: Assocation with human-papillomavirus-negative tumours
    • CROOK T, WREDE D, TIDY JA, MASON WP, EVANS DJ AND VOUSDEN KH. (1992). Clonal p53 mutation in primary cervical cancer: assocation with human-papillomavirus-negative tumours. Lancet, 339, 1070 - 1073.
    • (1992) Lancet , vol.339 , pp. 1070-1073
    • Crook, T.1    Wrede, D.2    Tidy, J.A.3    Mason, W.P.4    Evans, D.J.5    Vousden, K.H.6
  • 8
    • 0024544045 scopus 로고
    • The three mouse multidrug resistance (mdr) genes are expressed in a tissue-specific manner in normal mouse tissues
    • CROOP JM, RAYMOND M, WABER D, DEVAULT A, ARCECI RJ, GROSP P AND HOUSMAN DE. (1989). The three mouse multidrug resistance (mdr) genes are expressed in a tissue-specific manner in normal mouse tissues. Mol. Cell Biol., 9, 1346 - 1350.
    • (1989) Mol. Cell Biol. , vol.9 , pp. 1346-1350
    • Croop, J.M.1    Raymond, M.2    Waber, D.3    Devault, A.4    Arceci, R.J.5    Grosp, P.6    Housman, D.E.7
  • 9
    • 0025853776 scopus 로고
    • Tumorigenic potential associated with enhanced expression of a gene that is amplified in a mouse tumour cell line
    • FAKHARZADEH SS, TRUSKO SP AND GEORGE DL. (1991). Tumorigenic potential associated with enhanced expression of a gene that is amplified in a mouse tumour cell line. EMBO J., 10, 1565-1569.
    • (1991) EMBO J. , vol.10 , pp. 1565-1569
    • Fakharzadeh, S.S.1    Trusko, S.P.2    George, D.L.3
  • 10
    • 0027498314 scopus 로고
    • The mdm-2 oncogene can overcome wild-type p53 suppression of transformed cell growth
    • FINLAY CA. (1993). The mdm-2 oncogene can overcome wild-type p53 suppression of transformed cell growth. Mol. Cell Biol., 13, 301 - 306.
    • (1993) Mol. Cell Biol. , vol.13 , pp. 301-306
    • Finlay, C.A.1
  • 12
    • 0026648674 scopus 로고
    • Identification of programmed cell death in situ via specific labelling of nuclear DNA fragmentation
    • GAVRIELI Y, SHERMAN Y AND BEN-SASSON SA. (1992). Identification of programmed cell death in situ via specific labelling of nuclear DNA fragmentation. J. Cell Biol., 119, 493 - 501.
    • (1992) J. Cell Biol. , vol.119 , pp. 493-501
    • Gavrieli, Y.1    Sherman, Y.2    Ben-Sasson, S.A.3
  • 13
    • 0025038349 scopus 로고
    • Protein-binding elements in the promoter region of the mouse p53 gene
    • GINSBERG D, OREN M, YANIV M AND PIETTE J. (1990). Protein-binding elements in the promoter region of the mouse p53 gene. Oncogene, 5, 1285 - 1290.
    • (1990) Oncogene , vol.5 , pp. 1285-1290
    • Ginsberg, D.1    Oren, M.2    Yaniv, M.3    Piette, J.4
  • 16
    • 0023006005 scopus 로고
    • Isolation and expression of a complementary DNA that confers multidrug resistance
    • GROS P, BEN-NERIAH Y, CROOP JM AND HOUSMAN DE. (1986). Isolation and expression of a complementary DNA that confers multidrug resistance. Nature, 323, 728 - 731.
    • (1986) Nature , vol.323 , pp. 728-731
    • Gros, P.1    Ben-Neriah, Y.2    Croop, J.M.3    Housman, D.E.4
  • 17
    • 0027489384 scopus 로고
    • Clinical implications of the p53 tumor-suppressor gene
    • HARRIS CC AND HOLLSTEIN M. (1993). Clinical implications of the p53 tumor-suppressor gene. N. Engl. J. Med., 329, 1318 - 1327.
    • (1993) N. Engl. J. Med. , vol.329 , pp. 1318-1327
    • Harris, C.C.1    Hollstein, M.2
  • 18
    • 0025618980 scopus 로고
    • Mutant p53 cDNAs from human colorectal carcinomas can cooperate with ras in transformation of primary rat cells: A comparison of the 'hot spot' mutant phenotype
    • HINDS PW, FINLAY CA, QUARTIN RS, BAKER SJ, FEARON ER, VOGELSTEIN B AND LEVIN AJ. (1990). Mutant p53 cDNAs from human colorectal carcinomas can cooperate with ras in transformation of primary rat cells: a comparison of the 'hot spot' mutant phenotype. Cell Growth Different., 1, 571 - 580.
    • (1990) Cell Growth Different. , vol.1 , pp. 571-580
    • Hinds, P.W.1    Finlay, C.A.2    Quartin, R.S.3    Baker, S.J.4    Fearon, E.R.5    Vogelstein, B.6    Levin, A.J.7
  • 20
    • 33645830172 scopus 로고
    • A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants
    • JULIANO RL AND LING V. (1976). A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants. Biochim. Biophys. Acta, 455, 152 - 162.
    • (1976) Biochim. Biophys. Acta , vol.455 , pp. 152-162
    • Juliano, R.L.1    Ling, V.2
  • 21
    • 0028283265 scopus 로고
    • Transfection with a bcl-2 expression vector protects transplanted bone marrow from chemotherapy-induced myelosuppression
    • KONDO S, YIN D, MORIMURA T, ODA Y, KIKUCHI H AND TAKEUCHI J. (1994). Transfection with a bcl-2 expression vector protects transplanted bone marrow from chemotherapy-induced myelosuppression. Cancer Res., 54, 2928 - 2933.
    • (1994) Cancer Res. , vol.54 , pp. 2928-2933
    • Kondo, S.1    Yin, D.2    Morimura, T.3    Oda, Y.4    Kikuchi, H.5    Takeuchi, J.6
  • 22
    • 0029044606 scopus 로고
    • MDM2 protein confers the resistance of a human glioblastoma cell line to cisplatin-induced apoptosis
    • KONDO S, BARNETT GH, HARA H, MORIMURA T AND TAKEUCHI J. (1995). MDM2 protein confers the resistance of a human glioblastoma cell line to cisplatin-induced apoptosis. Oncogene. 10, 2001 - 2006.
    • (1995) Oncogene , vol.10 , pp. 2001-2006
    • Kondo, S.1    Barnett, G.H.2    Hara, H.3    Morimura, T.4    Takeuchi, J.5
  • 23
    • 0025876591 scopus 로고
    • The p53 tumour suppressor gene
    • LEVINE AJ, MOMAND J AND FINLAY CA. (1991). The p53 tumour suppressor gene. Nature, 351, 453 - 456.
    • (1991) Nature , vol.351 , pp. 453-456
    • Levine, A.J.1    Momand, J.2    Finlay, C.A.3
  • 24
    • 0027451668 scopus 로고
    • p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
    • LOWE SW, RULEY HE, JACKS T AND HOUSMAN DE. (1993). p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell, 74, 957 - 967.
    • (1993) Cell , vol.74 , pp. 957-967
    • Lowe, S.W.1    Ruley, H.E.2    Jacks, T.3    Housman, D.E.4
  • 26
    • 0026649648 scopus 로고
    • The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
    • MOMAND J, ZAMBETTI GP, OLSON DC, GEORGE D AND LEVINE AJ. (1992). The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation. Cell, 69, 1237-1245.
    • (1992) Cell , vol.69 , pp. 1237-1245
    • Momand, J.1    Zambetti, G.P.2    Olson, D.C.3    George, D.4    Levine, A.J.5
  • 27
    • 0026740449 scopus 로고
    • Amplification of a gene encoding a p53-associated protein in human sarcomas
    • OLINER JD, KINZLER KW, MELTZER PS, GEORGE DL AND VOGELSTEIN B. (1992). Amplification of a gene encoding a p53-associated protein in human sarcomas. Nature, 358, 80-83.
    • (1992) Nature , vol.358 , pp. 80-83
    • Oliner, J.D.1    Kinzler, K.W.2    Meltzer, P.S.3    George, D.L.4    Vogelstein, B.5
  • 29
    • 0027179604 scopus 로고
    • Identification and characterization of multiple mdm-2 proteins and mdm-2-p53 protein complexes
    • OLSON DC, MARECHAL V, MOMAND J, CHEN J, ROMOCKI C AND LEVINE AJ. (1993). Identification and characterization of multiple mdm-2 proteins and mdm-2-p53 protein complexes. Oncogene, 8, 2353-2360.
    • (1993) Oncogene , vol.8 , pp. 2353-2360
    • Olson, D.C.1    Marechal, V.2    Momand, J.3    Chen, J.4    Romocki, C.5    Levine, A.J.6
  • 31
    • 0027196974 scopus 로고
    • Amplification and overexpression of the MDM2 gene in a subset of human malignant gliomas without p53 mutations
    • REIFENBERGER G, LIU L, ICHIMURA K, SCHMIDT EE AND COLLINS VP. (1993). Amplification and overexpression of the MDM2 gene in a subset of human malignant gliomas without p53 mutations. Cancer Res., 53, 2736-2739.
    • (1993) Cancer Res. , vol.53 , pp. 2736-2739
    • Reifenberger, G.1    Liu, L.2    Ichimura, K.3    Schmidt, E.E.4    Collins, V.P.5
  • 32
    • 0021288268 scopus 로고
    • Amplification of specific DNA sequences correlates with multidrug-resistance in Chinese hamster cells
    • RONINSON IB, ABELSON HT, HOUSMAN DE, HOWELL N AND VARSHAVSKY A. (1984). Amplification of specific DNA sequences correlates with multidrug-resistance in Chinese hamster cells. Nature, 309, 626-628.
    • (1984) Nature , vol.309 , pp. 626-628
    • Roninson, I.B.1    Abelson, H.T.2    HOUSMAN, D.E.3    Howell, N.4    Varshavsky, A.5
  • 33
    • 0022975468 scopus 로고
    • Vinblastine photoaffinity labelling of a high molecular weight surface membrane glycoprotein specific for multidrug-resistant cells
    • SAFA AR, GLOVER CJ, MEYERS MB, BIEDLER JL AND FELSTAD RL. (1986). Vinblastine photoaffinity labelling of a high molecular weight surface membrane glycoprotein specific for multidrug-resistant cells. J. Biol. Chem., 261, 6137-6140.
    • (1986) J. Biol. Chem. , vol.261 , pp. 6137-6140
    • Safa, A.R.1    Glover, C.J.2    Meyers, M.B.3    Biedler, J.L.4    Felstad, R.L.5
  • 34
    • 0026722467 scopus 로고
    • Expression of the human multidrug resistance cDNA in insect cells generates a high activity drug-stimulated membrane ATPase
    • SARKADI B, PRICE EM, BOUCHER RC, GERMANN V AND SCABOROUGH GA. (1992). Expression of the human multidrug resistance cDNA in insect cells generates a high activity drug-stimulated membrane ATPase. J. Biol. Chem., 267, 4854-4858.
    • (1992) J. Biol. Chem. , vol.267 , pp. 4854-4858
    • Sarkadi, B.1    Price, E.M.2    Boucher, R.C.3    Germann, V.4    Scaborough, G.A.5
  • 35
    • 0025639158 scopus 로고
    • The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
    • SCHEFFNER M, WERNESS BA, HUIBREGSTE JM, LEVINE AJ AND HOWLEY PM. (1990). The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53. Cell, 63, 1129-1136.
    • (1990) Cell , vol.63 , pp. 1129-1136
    • Scheffner, M.1    Werness, B.A.2    Huibregste, J.M.3    Levine, A.J.4    Howley, P.M.5
  • 36
    • 0024378054 scopus 로고
    • Characterization of the multidrug resistance protein expressed in cell clones stably transfected with the mouse mdr1 cDNA
    • SCHURR E, RAYMOND M, BELL J AND GROS P. (1989). Characterization of the multidrug resistance protein expressed in cell clones stably transfected with the mouse mdr1 cDNA. Cancer Res., 49, 2729-2734.
    • (1989) Cancer Res. , vol.49 , pp. 2729-2734
    • Schurr, E.1    Raymond, M.2    Bell, J.3    Gros, P.4
  • 39
    • 0008632564 scopus 로고
    • Expression of a full-length cDNA for the human 'MDR1' gene confers resistance to colchicine, doxorubicine, and vinblastine
    • UEDA K, CARDARELLI C, GOTTESMAN MM AND PASTAN I. (1987). Expression of a full-length cDNA for the human 'MDR1' gene confers resistance to colchicine, doxorubicine, and vinblastine. Proc. Natl Acad. Sci. USA, 84, 3004-3008.
    • (1987) Proc. Natl Acad. Sci. USA , vol.84 , pp. 3004-3008
    • Ueda, K.1    Cardarelli, C.2    Gottesman, M.M.3    Pastan, I.4
  • 40
    • 0026669469 scopus 로고
    • p53 function and dysfunction
    • VOGHLSTEIN B AND KINZLER KW. (1992). p53 function and dysfunction. Cell, 70, 523-526.
    • (1992) Cell , vol.70 , pp. 523-526
    • Voghlstein, B.1    Kinzler, K.W.2
  • 41
    • 0028328912 scopus 로고
    • Induction of apoptosis in murine ACTH-secreting pituitary adenoma cells by bromocriptine
    • YIN D, KONDO S, TAKEUCHI J AND MORIMURA T. (1994). Induction of apoptosis in murine ACTH-secreting pituitary adenoma cells by bromocriptine. FEBS Lett., 339, 73-75.
    • (1994) FEBS Lett. , vol.339 , pp. 73-75
    • Yin, D.1    Kondo, S.2    Takeuchi, J.3    Morimura, T.4
  • 42
    • 0027191153 scopus 로고
    • The core promoter region of the P-glycoprotein gene is sufficient to confer differential responsiveness to wild-type and mutant p53
    • ZASTAWNY RL, SALVINO R, CHEN J, BENCHIMOL S AND LING V. (1993). The core promoter region of the P-glycoprotein gene is sufficient to confer differential responsiveness to wild-type and mutant p53. Oncogene, 8, 1529-1535.
    • (1993) Oncogene , vol.8 , pp. 1529-1535
    • Zastawny, R.L.1    Salvino, R.2    Chen, J.3    Benchimol, S.4    Ling, V.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.