메뉴 건너뛰기




Volumn 45, Issue 5, 1996, Pages 543-551

The sequential administration of growth hormone-releasing hormone followed 120 minutes later by hexarelin, as an effective test to assess the pituitary GH reserve in man

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE; GROWTH HORMONE RELEASING FACTOR; HEXARELIN; SERMORELIN;

EID: 0029822968     PISSN: 03000664     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2265.1996.00841.x     Document Type: Article
Times cited : (12)

References (43)
  • 3
    • 0026016294 scopus 로고
    • 2 stimulate growth hormone release through distinct receptor sites
    • 2 stimulate growth hormone release through distinct receptor sites. Journal of Endocrinology, 129, 11-19.
    • (1991) Journal of Endocrinology , vol.129 , pp. 11-19
    • Blake, A.D.1    Smith, R.G.2
  • 4
    • 0018899801 scopus 로고
    • Structure-activity relationships of a synthetic pentapeptide that specifically releases GH in vitro
    • Bowers, C.Y., Momany, F.A., Chang, D., Hong, A. & Chang, K. (1980) Structure-activity relationships of a synthetic pentapeptide that specifically releases GH in vitro. Endocrinology, 106, 663-667.
    • (1980) Endocrinology , vol.106 , pp. 663-667
    • Bowers, C.Y.1    Momany, F.A.2    Chang, D.3    Hong, A.4    Chang, K.5
  • 5
    • 0021322884 scopus 로고
    • On the in vitro and in vivo activity of a new synthetic hexapeptide that acts on the pituitary to specifically release growth hormone
    • Bowers, C.Y., Momany, F.A., Reynolds, G.A. & Hong, A. (1984) On the in vitro and in vivo activity of a new synthetic hexapeptide that acts on the pituitary to specifically release growth hormone. Endocrinology, 114, 1537-1545.
    • (1984) Endocrinology , vol.114 , pp. 1537-1545
    • Bowers, C.Y.1    Momany, F.A.2    Reynolds, G.A.3    Hong, A.4
  • 7
    • 0025809717 scopus 로고
    • On the actions of the growth hormone-releasing hexapeptide, GHRP-6
    • Bowers, C.Y., Sartor, A.O., Reynolds, G.A. & Badger, T.M. (1991) On the actions of the growth hormone-releasing hexapeptide, GHRP-6. Endocrinology, 128, 2027-2035.
    • (1991) Endocrinology , vol.128 , pp. 2027-2035
    • Bowers, C.Y.1    Sartor, A.O.2    Reynolds, G.A.3    Badger, T.M.4
  • 8
    • 0028566216 scopus 로고
    • Value and limits of pharmacological and physiological tests to diagnose growth hormone (GH) deficiency and predict therapy response: First and second retesting during replacement therapy of patients defined as GH deficient
    • Cacciari, E., Tassoni, P., Cicognani, A., Pirazolli, P., Salardi, S., Balsamo, A., Cassio, A., Zucchini, S., Colli, C., Tassinari, D., Tani, G. & Gualardi, S. (1994) Value and limits of pharmacological and physiological tests to diagnose growth hormone (GH) deficiency and predict therapy response: first and second retesting during replacement therapy of patients defined as GH deficient. Journal of Clinical Endocrinology Metabolism, 79, 1663-1669.
    • (1994) Journal of Clinical Endocrinology Metabolism , vol.79 , pp. 1663-1669
    • Cacciari, E.1    Tassoni, P.2    Cicognani, A.3    Pirazolli, P.4    Salardi, S.5    Balsamo, A.6    Cassio, A.7    Zucchini, S.8    Colli, C.9    Tassinari, D.10    Tani, G.11    Gualardi, S.12
  • 10
    • 10544251706 scopus 로고
    • The Spanish experience on the rationalization of expensive treatments for endocrine disorders
    • abstr.
    • Casanueva, F.F. (1995) The Spanish experience on the rationalization of expensive treatments for endocrine disorders. Journal of Endocrinology, 144 (Suppl. S42) (abstr.).
    • (1995) Journal of Endocrinology , vol.144 , Issue.SUPPL. S42
    • Casanueva, F.F.1
  • 11
    • 0024453883 scopus 로고
    • The effects of a growth hormone-releasing peptide and growth hormone-releasing factor in conscious and anaesthetized rats
    • Clark, R.G., Carlsson, L.M.S., Trojnar, J. & Robinson, I.C.A.F. (1989) The effects of a growth hormone-releasing peptide and growth hormone-releasing factor in conscious and anaesthetized rats. Journal of Neuroendocrinology, 1, 249-255.
    • (1989) Journal of Neuroendocrinology , vol.1 , pp. 249-255
    • Clark, R.G.1    Carlsson, L.M.S.2    Trojnar, J.3    Robinson, I.C.A.F.4
  • 12
    • 0024396484 scopus 로고
    • Binding of a growth hormone releasing hexapeptide to specific hypothalamic and pituitary binding sites
    • Codd, E.E., Shu, A.Y.L. & Walker, R.F. (1989) Binding of a growth hormone releasing hexapeptide to specific hypothalamic and pituitary binding sites. Neuropharmacology, 28, 1139-1144.
    • (1989) Neuropharmacology , vol.28 , pp. 1139-1144
    • Codd, E.E.1    Shu, A.Y.L.2    Walker, R.F.3
  • 13
    • 0027419864 scopus 로고
    • Massive growth hormone (GH) discharge in obese subjects after the combined administration of GH-releasing hormone and GHRP-6: Evidence for a marked somatotroph secretory capability in obesity
    • Cordido, F., Peñalva, A., Dieguez, C. & Casanueva, F.F. (1993) Massive growth hormone (GH) discharge in obese subjects after the combined administration of GH-releasing hormone and GHRP-6: Evidence for a marked somatotroph secretory capability in obesity. Journal of Clinical Endocrinology and Metabolism, 76, 819-823.
    • (1993) Journal of Clinical Endocrinology and Metabolism , vol.76 , pp. 819-823
    • Cordido, F.1    Peñalva, A.2    Dieguez, C.3    Casanueva, F.F.4
  • 14
    • 0023633340 scopus 로고
    • Growth disorders in childhood
    • Cuttler, L. (1987) Growth disorders in childhood. Pediatrician, 14, 109-120.
    • (1987) Pediatrician , vol.14 , pp. 109-120
    • Cuttler, L.1
  • 15
    • 0025740899 scopus 로고
    • Growth hormone (GH) secretion during continuous infusion of GH releasing peptide: Partial response attenuation
    • De Bell, W.K., Pezzoli, S.S. & Thorner, M.O. (1991) Growth hormone (GH) secretion during continuous infusion of GH releasing peptide: Partial response attenuation. Journal of Clinical Endocrinology and Metabolism, 72, 1312-1316.
    • (1991) Journal of Clinical Endocrinology and Metabolism , vol.72 , pp. 1312-1316
    • De Bell, W.K.1    Pezzoli, S.S.2    Thorner, M.O.3
  • 16
    • 0028944463 scopus 로고
    • Clinical aspects of growth hormone deficiency in adults
    • De Boer, H., Blok, G.-J. & Van der Veen, E.A. (1995). Clinical aspects of growth hormone deficiency in adults. Endocrine Reviews, 16, 63-86.
    • (1995) Endocrine Reviews , vol.16 , pp. 63-86
    • De Boer, H.1    Blok, G.-J.2    Van Der Veen, E.A.3
  • 17
    • 0028922330 scopus 로고
    • Influence of metabolic substrates and obesity on growth hormone secretion
    • Dieguez, C. & Casanueva, F.F. (1995) Influence of metabolic substrates and obesity on growth hormone secretion. Trends in Endocrinology Metabolism, 6, 55-59.
    • (1995) Trends in Endocrinology Metabolism , vol.6 , pp. 55-59
    • Dieguez, C.1    Casanueva, F.F.2
  • 18
    • 0023853012 scopus 로고
    • Growth hormone neuroregulation and its alterations in disease states
    • Dieguez, C., Page, M.D. & Scanlon, M.F. (1988) Growth hormone neuroregulation and its alterations in disease states. Clinical Endocrinology, 28, 109-143.
    • (1988) Clinical Endocrinology , vol.28 , pp. 109-143
    • Dieguez, C.1    Page, M.D.2    Scanlon, M.F.3
  • 20
    • 0028265587 scopus 로고
    • Growth hormone-releasing activity of hexarelin, a new synthetic hexapeptide, after intravenous, subcutaneous, intranasal, and oral administration in man
    • Chigo, E., Arvat, E., Gianotti, L., Imbimbo, B.P., Lenaerts, V., Deghenghi, R. & Camanni, F. (1994) Growth hormone-releasing activity of hexarelin, a new synthetic hexapeptide, after intravenous, subcutaneous, intranasal, and oral administration in man. Journal of Clinical Endocrinology and Metabolism, 78, 693-698.
    • (1994) Journal of Clinical Endocrinology and Metabolism , vol.78 , pp. 693-698
    • Chigo, E.1    Arvat, E.2    Gianotti, L.3    Imbimbo, B.P.4    Lenaerts, V.5    Deghenghi, R.6    Camanni, F.7
  • 21
    • 0026607276 scopus 로고
    • Pituitary adenylate cyclase activating polypeptide, growth hormone (GH)-releasing peptide and GH-releasing hormone stimulate GH release through distinct pituitary receptors
    • Goth, M.I., Lyons, C.E., Canny. B.J. & Thorner, M.O. (1992) Pituitary adenylate cyclase activating polypeptide, growth hormone (GH)-releasing peptide and GH-releasing hormone stimulate GH release through distinct pituitary receptors. Endocrinology, 130, 939-944.
    • (1992) Endocrinology , vol.130 , pp. 939-944
    • Goth, M.I.1    Lyons, C.E.2    Canny, B.J.3    Thorner, M.O.4
  • 22
    • 0026762569 scopus 로고
    • Clinical usefulness of urinary growth hormone measurements in normal and short children according to different expressions of urinary growth hormone data
    • Granada, M.L., Sanmarti, A., Lucas, A., Salinas, I., Cuatrecasas, J.M., Foz, M., Carrascosa, A. & Audí, L. (1992) Clinical usefulness of urinary growth hormone measurements in normal and short children according to different expressions of urinary growth hormone data. Pediatric Research, 32, 73-76.
    • (1992) Pediatric Research , vol.32 , pp. 73-76
    • Granada, M.L.1    Sanmarti, A.2    Lucas, A.3    Salinas, I.4    Cuatrecasas, J.M.5    Foz, M.6    Carrascosa, A.7    Audí, L.8
  • 24
    • 0029150025 scopus 로고
    • Short stature and growth hormone deficiency
    • Hindmarsh, P.C. & Brook, C.G.D. (1995) Short stature and growth hormone deficiency. Clinical Endocrinology, 43, 133-142.
    • (1995) Clinical Endocrinology , vol.43 , pp. 133-142
    • Hindmarsh, P.C.1    Brook, C.G.D.2
  • 25
    • 0028903627 scopus 로고
    • Growth hormone-releasing peptide and its analogues: Novel stimuli to growth hormone release
    • Korbonits, M. & Grossman, A.B. (1995) Growth hormone-releasing peptide and its analogues: novel stimuli to growth hormone release. Trends in Endocrinology and Metabolism, 6, 43-49.
    • (1995) Trends in Endocrinology and Metabolism , vol.6 , pp. 43-49
    • Korbonits, M.1    Grossman, A.B.2
  • 26
    • 0029097574 scopus 로고
    • The effect of an opiate antagonist on the hormonal changes induced by hexarelin
    • Korbonits, M., Trainer, J.P. & Besser, G.M. (1995) The effect of an opiate antagonist on the hormonal changes induced by hexarelin. Clinical Endocrinology, 43, 365-371.
    • (1995) Clinical Endocrinology , vol.43 , pp. 365-371
    • Korbonits, M.1    Trainer, J.P.2    Besser, G.M.3
  • 27
    • 0029044139 scopus 로고
    • Growth hormone (GH) responses to the combined administration of GH-releasing hormone plus GH-releasing peptide 6 in adults with GH deficiency
    • Leal, A., Garcia, E., Astorga, R., Casanueva, F.F. & Dieguez, C. (1995) Growth hormone (GH) responses to the combined administration of GH-releasing hormone plus GH-releasing peptide 6 in adults with GH deficiency. European Journal of Endocrinology, 132, 712-715.
    • (1995) European Journal of Endocrinology , vol.132 , pp. 712-715
    • Leal, A.1    Garcia, E.2    Astorga, R.3    Casanueva, F.F.4    Dieguez, C.5
  • 28
    • 0027988189 scopus 로고
    • Inhibition of growth hormone release after the combined administration of GHRH and GHRP-6 in patients with Cushing's syndrome
    • Leal, A., Pumar, A., Garcia, E., Dieguez, C. & Casanueva, F.F. (1994) Inhibition of growth hormone release after the combined administration of GHRH and GHRP-6 in patients with Cushing's syndrome. Clinical Endocrinology, 41, 649-654.
    • (1994) Clinical Endocrinology , vol.41 , pp. 649-654
    • Leal, A.1    Pumar, A.2    Garcia, E.3    Dieguez, C.4    Casanueva, F.F.5
  • 29
    • 0028832011 scopus 로고
    • Growth hormone secretion after the administration of GHRP-6, or GHRP-6 combined with GHRH does not decline in late adulthood
    • Micic, D., Popovic, V., Kendereski, A., Macut, D., Casanueva, F.F. & Dieguez, C. (1995) Growth hormone secretion after the administration of GHRP-6, or GHRP-6 combined with GHRH does not decline in late adulthood. Clinical Endocrinology, 42, 191-194.
    • (1995) Clinical Endocrinology , vol.42 , pp. 191-194
    • Micic, D.1    Popovic, V.2    Kendereski, A.3    Macut, D.4    Casanueva, F.F.5    Dieguez, C.6
  • 30
    • 0021368643 scopus 로고
    • Conformational energy studies and in vitro activity data on active GH releasing peptides
    • Momany, F.A., Bowers, C.Y., Reynolds, G.A., Hong, A. & Newlander, K. (1984) Conformational energy studies and in vitro activity data on active GH releasing peptides. Endocrinology, 144, 1531-1536.
    • (1984) Endocrinology , vol.144 , pp. 1531-1536
    • Momany, F.A.1    Bowers, C.Y.2    Reynolds, G.A.3    Hong, A.4    Newlander, K.5
  • 31
    • 0027390227 scopus 로고
    • Effect of growth hormone (GH)-releasing hormone (GHRH), atropine, pyridostigmine, or hypoglycemia on GHRP-6-induced GH secretion in man
    • Peñalva, A., Carballo, A., Pombo, M., Casanueva, F.F. & Dieguez, C. (1993) Effect of growth hormone (GH)-releasing hormone (GHRH), atropine, pyridostigmine, or hypoglycemia on GHRP-6-induced GH secretion in man. Journal of Clinical Endocrinology and Metabolism, 76, 168-171.
    • (1993) Journal of Clinical Endocrinology and Metabolism , vol.76 , pp. 168-171
    • Peñalva, A.1    Carballo, A.2    Pombo, M.3    Casanueva, F.F.4    Dieguez, C.5
  • 32
    • 0028807113 scopus 로고
    • Absence of growth hormone (GH) secretion after the administration of either GH-releasing hormone (GHRH), GH-releasing peptide (GHRP-6) or GHRH plus GHRP-6, in children with neonatal pituitary stalk transaction
    • Pombo, M., Barreiro, J., Peñalva, A., Peino, R., Dieguez, C. & Casanueva, F.F. (1995) Absence of growth hormone (GH) secretion after the administration of either GH-releasing hormone (GHRH), GH-releasing peptide (GHRP-6) or GHRH plus GHRP-6, in children with neonatal pituitary stalk transaction. Journal of Clinical Endocrinology and Metabolism, 80, 3180-3184.
    • (1995) Journal of Clinical Endocrinology and Metabolism , vol.80 , pp. 3180-3184
    • Pombo, M.1    Barreiro, J.2    Peñalva, A.3    Peino, R.4    Dieguez, C.5    Casanueva, F.F.6
  • 33
    • 0028968462 scopus 로고
    • Blocked growth hormone-releasing peptide (GHRP-6)-induced GH secretion and absence of the synergic action of GHRP-6 plus GH-releasing hormone in patients with hypothalamopituitary disconnection: Evidence that GHRP-6 main action is exerted at the hypothalamic level
    • Popovic, V., Damjanovic, S., Micic, D., Djurovic, M., Dieguez, C. & Casanueva, F.F. (1995) Blocked growth hormone-releasing peptide (GHRP-6)-induced GH secretion and absence of the synergic action of GHRP-6 plus GH-releasing hormone in patients with hypothalamopituitary disconnection: evidence that GHRP-6 main action is exerted at the hypothalamic level. Journal of Clinical Endocrinology and Metabolism, 80, 942-947.
    • (1995) Journal of Clinical Endocrinology and Metabolism , vol.80 , pp. 942-947
    • Popovic, V.1    Damjanovic, S.2    Micic, D.3    Djurovic, M.4    Dieguez, C.5    Casanueva, F.F.6
  • 35
    • 0028293475 scopus 로고
    • Growth hormone (GH)-releasing peptide stimulation of GH release from human somatotroph adenoma cells: Interaction with GH-releasing hormone, thyrotropin-releasing hormone, and octreotide
    • Renner, U., Brockmeier, S., Strasburger, C.J., Lange, M., Schopohl, J., Müller, O.A., Werder, Kv. & Stalla, O.K. (1994) Growth hormone (GH)-releasing peptide stimulation of GH release from human somatotroph adenoma cells: interaction with GH-releasing hormone, thyrotropin-releasing hormone, and octreotide. Journal of Clinical Endocrinology and Metabolism, 78, 1090-1096.
    • (1994) Journal of Clinical Endocrinology and Metabolism , vol.78 , pp. 1090-1096
    • Renner, U.1    Brockmeier, S.2    Strasburger, C.J.3    Lange, M.4    Schopohl, J.5    Müller, O.A.6    Werder, K.7    Stalla, O.K.8
  • 36
    • 0023759047 scopus 로고
    • The advantage of measuring stimulated as compared with spontaneous growth hormone levels in the diagnosis of growth hormone deficiency
    • Rose, S.R., Ross, S.L., Uriarte, M., Barnes, K.M., Cassorla, F.G. & Cutler, J.B. (1988) The advantage of measuring stimulated as compared with spontaneous growth hormone levels in the diagnosis of growth hormone deficiency. New England Journal of Medicine, 319, 201-207.
    • (1988) New England Journal of Medicine , vol.319 , pp. 201-207
    • Rose, S.R.1    Ross, S.L.2    Uriarte, M.3    Barnes, K.M.4    Cassorla, F.G.5    Cutler, J.B.6
  • 38
    • 0023555150 scopus 로고
    • GH feedback occurs through modulation of hypothalamic somatostatin under cholinergic control: Studies with pyridostigmine and GHRH
    • Ross, R.J.M., Tsagarakis, S., Grossman, A., Nhagabong, L., Touzel, R.J., Rees, L.H. & Besser, G.M. (1988) GH feedback occurs through modulation of hypothalamic somatostatin under cholinergic control: studies with pyridostigmine and GHRH. Clinical Endocrinology, 27, 727-733.
    • (1988) Clinical Endocrinology , vol.27 , pp. 727-733
    • Ross, R.J.M.1    Tsagarakis, S.2    Grossman, A.3    Nhagabong, L.4    Touzel, R.J.5    Rees, L.H.6    Besser, G.M.7
  • 39
    • 0021982065 scopus 로고
    • 2 and human pancreatic growth hormone-releasing factor -44-NH2 in rat primary pituitary cell monolayer culture
    • 2 and human pancreatic growth hormone-releasing factor -44-NH2 in rat primary pituitary cell monolayer culture. Endocrinology, 116, 952-957.
    • (1985) Endocrinology , vol.116 , pp. 952-957
    • Sartor, O.1    Bowers, C.Y.2    Chang, D.3
  • 41
    • 0027752056 scopus 로고
    • Metabolic status and growth hormone secretion in man
    • Vance, M.L. (1993) Metabolic status and growth hormone secretion in man. Journal of Paediatric Endocrinology, 6, 3-4.
    • (1993) Journal of Paediatric Endocrinology , vol.6 , pp. 3-4
    • Vance, M.L.1
  • 43
    • 0026045803 scopus 로고
    • Robust growth hormone (GH) secretion in aged female rats co-administered GH-releasing hexapeptide (GHRP-6) and GH-releasing hormone (GHRH)
    • Walker, R.F., Yang, S.W. & Bercu, B.B. (1991) Robust growth hormone (GH) secretion in aged female rats co-administered GH-releasing hexapeptide (GHRP-6) and GH-releasing hormone (GHRH). Life Sciences, 49, 1499-1504.
    • (1991) Life Sciences , vol.49 , pp. 1499-1504
    • Walker, R.F.1    Yang, S.W.2    Bercu, B.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.