Pentoxifylline maintains vascular endothelial cell function during hyperdynamic and hypodynamic sepsis

Surgery

Volumn 120, Issue 2, 1996, Pages 367-373

  Wang, P ^a   Wood, T J ^a   Ba, Z F ^a   Chaudry, I H ^a  

^a RHODE ISLAND HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PENTOXIFYLLINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL FUNCTION; CONTROLLED STUDY; DRUG EFFECT; ENDOTHELIUM CELL; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SEPSIS;

EID: 0029822874     PISSN: 00396060     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0039-6060(96)80311-4     Document Type: Article

References (25)

1. Steeb GD Wilson MA Garrison RN Pentoxifylline preserves small-intestine microvascular blood flow during bacteremia Surgery 112 1992 756 764
2. Hadjiminas DJ McMasters KM Robertson SE Cheadle WG Enhanced survival from cecal ligation and puncture with pentoxifylline is associated with altered neutrophil trafficking and reduced interleukin-1β expression but not inhibition of tumor necrosis factor synthesis Surgery 116 1994 348 355
3. Chalkiadakis GE Kostakis A Karayannacos PE Pentoxifylline in the treatment of experimental peritonitis in rats Arch Surg 120 1985 1141 1144
4. Lundblad R Ekstrom P Giercksky K-E Pentoxifylline improves surival and reduces tumor necrosis factor, interleukin-6 and endothelin-1 in fulminant intra-abdominal sepsis in rats Shock 3 1995 210 215
5. Zhang H Spapen H Benlabed M Nguyen DT Buurman WA Vincent JL Pentoxifylline improves the tissue extraction capacities during endotoxic shock Shock 2 1994 90 97
6. Refsum SE Norwood W Rowlands BJ Boston VE Pentoxifylline improves resting membrane potential in sepsis J Pediatr Surg 28 1993 1144 1146
7. Breuille D Farge MC Rose F Arnal M Attaix D Obled C Pentoxifylline decreases body weight loss and muscle protein wasting characteristics of sepsis Am J Physiol 265 1993 E660 E666
8. Wang P Ba ZF Zhou M Tait SM Chaudry IH Pentoxifylline restores cardiac output and tissue perfusion following traumahemorrhage and decreases susceptibility to sepsis Surgery 114 1993 352 359
9. Doherty GM Jensen C Alexander HR Buresh CM Norton JA Pentoxifylline suppression of tumor necrosis factor gene transcription Surgery 110 1991 192 198
10. Wang P Ba ZF Morrison MH Ayala A Chaudry IH Mechanism of the beneficial effects of pentoxifylline on hepatocellular function following trauma-hemorrhage and resuscitation Surgery 112 1992 451 458
11. Wichterman KA Baue AE Chaudry IH Sepsis and septic shock—a review of laboratory models and a proposal J Surg REs 29 1980 189 201
12. Wang P Ba ZF Chaudry IH Endothelial cell dysfunction occurs very early following trauma-hemorrhage and persists despite fluid resuscitation Am J Physiol 265 1993 H973 H979
13. Moncada S Palmer RMJ Higgs EA Nitric oxide: physiology, pathophysiology, and pharmacology Pharmacol Rev 43 1991 109 142
14. Myers PR Wright TF Tanner MA Adams HR EDRF and nitric oxide production in cultured endothelial cells: direct inhibition by E. coli endotoxin Am J Physiol 262 1992 H710 H718
15. Parker JL Adams HR Selective inhibition of endothelium-dependent vasodilator capacity by Escherichia coli endotoxemia Circ Res 72 1993 539 551
16. Young JS Headrick JP Berne RM Endothelial-dependent and-independent responses in the thoracic aorta during endotoxic shock Circ Shock 35 1991 25 30
17. Wang P Ba ZF Chaudry IH Nitric oxide: To block or enhance its production during sepsis? Arch Surg 129 1994 1137 1143
18. Wang P Ba ZF Chaudry IH Endothelium-dependent relaxation is depressed at the marco- and microcirculatory levels during sepsis Am J Physiol 269 1995 R988 R994
19. Siegfried MR Carey C Ma XL Lefer AM Beneficial effects of SPM-5185, a cysteine-containing NO donor in myocardial ischemia-reperfusion Am J Physiol 263 1992 H771 H777
20. Lorente JA Landin L Renes E Role of nitric oxide in the hemodynamic changes of sepsis Crit Care Med 21 1993 759 767
21. Zabel P Schade FU Schlaak M Inhibition of endogenous TNF formation by pentoxifylline Immunobiology 187 1993 447 463
22. Greenberg S Xie J Wang Y Tumor necrosis factor-alpha inhibits endothelium-dependent relaxation J Appl Physiol 74 1993 2394 2403
23. Wang P Ba ZF Chaudry IH Administration of tumor necrosis factor-α in vivo depresses endothelium-dependent relaxation Am J Physiol 266 1994 H2535 H2541
24. Ertel W Morrison MH Wang P Ba ZF Ayala A Chaudry IH The complex pattern of cytokines in sepsis—association between prostaglandins, cachectin and interleukins Ann Surg 214 1991 141 148
25. Palmer RMJ The discovery of nitric oxide in the vessel wall: a unifying concept in the pathogenesis of sepsis Arch Surg 128 1993 396 401