Differential regulation of 5-hydroxytryptamine release by GABA(A) and GABA(B) receptors in midbrain raphe nuclei and forebrain of rats

British Journal of Pharmacology

Volumn 119, Issue 7, 1996, Pages 1375-1384

  Tao, Rui ^b   Ma, Zhiyuan ^b   Auerbach, Sidney B ^a,b  

^a RUTGERS UNIVERSITY   (United States)

^b RUTGERS UNIVERSITY   (United States)

Author keywords

5 hydroxytryptamine (5 HT) release; Dorsal raphe nucleus; GABA receptor; Median raphe nucleus; Microdialysis

Indexed keywords

2 HYDROXYSACLOFEN; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID B RECEPTOR; BACLOFEN; BICUCULLINE; MUSCIMOL; PHACLOFEN; SEROTONIN;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DORSAL RAPHE NUCLEUS; FOREBRAIN; INTRACEREBRAL DRUG ADMINISTRATION; MALE; MEDIAN RAPHE NUCLEUS; MESENCEPHALON; MICRODIALYSIS; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; RAPHE NUCLEUS; RAT; SEROTONIN RELEASE; SEROTONINERGIC NERVE CELL;

EID: 0029822667     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1996.tb16049.x     Document Type: Article

References (45)

1. AUERBACH, S.B., LUNDBERG, J.F. & HJORTH, S. (1995). Differential inhibition of serotonin release by 5-HT and NA reuptake blockers after systemic administration. Neuropharmacology, 34, 89-96.
2. AUERBACH, S.B., MINZENBERG, M.J. & WILKINSON, L.O. (1989). Extracellular serotonin and 5-hydroxyindoleacetic acid in hypothalamus of the unanesthetized rat measured by in vivo dialysis coupled to high-performance liquid chromatography with electrochemical detection: dialysate serotonin reflects neuronal release. Brain Res., 499, 281-290.
3. BELIN, M.F., AGUERA, M., TAPPAZ, M , MCRAE-DEGUERCE, A., BOBILLIER, P. & PUJOL, J.F. (1979). GABA-accumulating neurons in the nucleus raphe dorsalis and periaqueductal gray in the rat: a biochemical and radioautographic study. Brain Res., 170, 279-297.
4. BLIER, P., SERRANO, A. & SCATTON, B. (1990). Differential responsiveness of the rat dorsal and median raphe 5-HT systems to 5-HT1 receptor agonists and p-chloroamphetamine. Synapse, 5, 120-133.
5. BOSKER, F., KLOMBMAKERS, A. & WESTENBERG, H. (1994). 5-Hydroxytryptamine in median raphe nucleus of the conscious rat is decreased by nanomolar concentrations of 8-hydroxy-2-(di-n-propylamino)tetralin and is sensitive to tetrodotoxin. J. Neurochem., 63, 2165-2171.
6. BOWERY, N.G., HILL, D.R., HUDSON, A.L., DOBLE, A., MIDDLE-MISS, D.N., SHAW, J. & TURNBULL, M. (1980). (-)Baclofen decreases neurotransmitter release in the mammalian CNS by an action at a novel GABA receptor. Nature, 283, 92-94.
7. CHAPUT, Y., DE MONTIGNY, C. & BLIER, P. (1986). Effects of a selective 5-HT reuptake blocker, citalopram, on the sensitivity of 5-HT autoreceptors: electrophysiological studies in the rat brain. Naunyn-Schmiedeberg's Arch. Pharmacol., 333, 342-348.
8. B receptors in the central nervous system. Nature, 332, 156-158.
9. DYKSTRA, K.H., HSIAO, J.K., MORRISON, P.F., BUNGAY, P.M., MEFFORD, I.N., SCULLY, M.N. & DEDRICK, R.L. (1992). Quantitative examination of tissue concentration profiles associated with microdialysis. J. Neurochem., 58, 931-940.
10. FORCHETTI, C.M. & MEEK, J.L. (1981). Evidence for a tonic GABAergic control of serotonin neurons in the median raphe nucleus. Brain Res., 206, 208-212.
11. GALLAGER, D.W. & AGHAJANIAN, G.K. (1976). Effect of anti-psychotic drugs on the firing of dorsal raphe cells. II. Reversal by picrotoxin. Eur. J. Pharmacol., 39, 357-364.
12. HERY, F. & TERNAUX, J.P. (1981). Regulation of release processes in central serotoninergic neurons. J. Physiol. (Paris), 77, 287-301.
13. B sites in rat brain. Nature, 290, 149-152.
14. HJORTH, S. (1992). Functional differences between ascending 5-HT systems. Adv. Biosci., 85, 203-218.
15. INNIS, R.B. & AGHAJANIAN, G.K. (1987). Pertussis toxin blocks 5-HT1A and GABAB receptor-mediated inhibition of serotonergic neurons. Eur. J. Pharmacol., 143, 195-204.
16. JACOBS, B.L. & FORNAL, C.A. (1991). Activity of brain serotonergic neurons in the behaving animal. Pharmacol. Rev., 43, 563-578.
17. KALEN, P., STRECKER, R.E , ROSENGREN, E. & BJORKLUND, A. (1988). Endogenous release of neuronal serotonin and 5-hydroxyindoleacetic acid in the caudate-putamen of the rat as revealed by intracerebral dialysis coupled to high-performance liquid chromatography with fluorimetric detection. J. Neurochem., 51, 1422-1435.
18. KALEN, P., STRECKER, R.E., ROSENGREN, E. & BJORKLUND, A. (1989). Regulation of striatal serotonin release by the lateral habenula-dorsal raphe pathway in the rat as demonstrated by in vivo microdialysis: role of excitatory amino acids and GABA. Brain Res., 492, 187-202.
19. KINNEY, G.G., KOCSIS, B. & VERTES, R.P. (1995). Injections of muscimol into the median raphe nucleus produce hippocampal theta rhythm in the urethane anesthetized rat. Psychopharmacology, 120, 244-248.
20. LEVINE, E.S. & JACOBS, B.L. (1992). Neurochemical afferents controlling the activity of serotonergic neurons in the dorsal raphe nucleus: microiontophoretic studies in the awake cat. J. Neurosci., 12, 4037-4044.
21. MAMOUNAS, L.A. & MOLLIVER, M.E. (1988). Evidence for dual serotonergic projections to neocortex: axons from the dorsal and median raphe nuclei are differentially vulnerable to the neurotoxin p-chloroamphetamine (PCA). Exp. Neurol., 102, 23-26.
22. A receptor: New insights from single channel recording. Synapse, 1, 96-101.
23. NEWBERRY, N.R. & NICOLL, R.A. (1985). Comparison of the action of baclofen with gamma-aminobutyric acid on rat hippocampal pyramidal cells in vitro. J. Physiol., 360, 161-185.
24. NISHIKAWA, T. & SCATTON, B. (1983). Evidence for a GABAergic inhibitory influence on serotonergic neurons originating from the dorsal raphe. Brain Res., 279, 325-329.
25. NISHIKAWA, T. & SCATTON, B. (1985a). Inhibitory influence of GABA on central serotonergic transmission. Involvement of the habenulo-raphe pathways in the GABAergic inhibition of ascending cerebral serotonergic neurons. Brain Res., 331, 81-90.
26. NISHIKAWA, T. & SCATTON, B. (1985b). Inhibitory influence of GABA on central serotonergic transmission. Raphe nuclei as the neuroanatomical site of the GABAergic inhibition of cerebral serotonergic neurons. Brain Res., 331, 91-103.
27. PAXINOS, G. & WATSON, C. (1982). The Rat Brain in Stereotaxic Coordinates. Sydney: Academic Press.
28. REISINE, T.D., SOUBRIE, P., ARTAUD, F. & GLOWINSKI, J. (1982). Involvement of lateral habenula-dorsal raphe neurons in the differential regulation striatal and nigral serotonergic transmission in cats. J. Neurosci., 2, 1062-1071.
29. ROMANDINI, S. & SAMANIN, R. (1984). Muscimol injection in the nucleus raphe dorsalis blocks the antinociceptive effect of morphine in rats: apparent lack of 5-hydroxytryptamine involvement in muscimol's effect. Br. J. Pharmacol., 81, 25-29.
30. RUTTER, J.J., GUNDLAH, C. & AUERBACH, S.B. (1995). Systemic uptake inhibition decreases serotonin release via somatodendritic autoreceptor activation. Synapse, 20, 225-233.
31. B receptor-mediated inhibition of serotonin release in the rat brain. Naunyn-Schmiedeberg's Arch. Pharmacol., 26, 99-105.
32. SHARP, T., BRAMWELL, S.R., CLARK, D. & GRAHAME-SMITH, D.G. (1989a). In vivo measurement of extracellular 5-hydroxytryptamine in hippocampus of the anaesthetized rat using microdialysis: changes in relation to 5-hydroxytryptaminergic neuronal activity. J. Neurochem., 53, 234-240.
33. SHARP, T., BRAMWELL, S.R., HJORTH, S. & GRAHAME-SMITH, D.G. (1989b). Pharmacological characterization of 8-OH-DPAT-induced inhibition of rat hippocampal 5-HT release in vivo as measured by microdialysis. Br. J. Pharmacol., 98, 989-997.
34. SMITH, D. & GALLAGER, D.W. (1987). GABA, benzodiazepine and serotonergic receptor development in the dorsal raphe nucleus: electrophysiological studies. Develop. Brain Res., 35, 191-198.
35. TAO, R. & AUERBACH, S.B. (1994). Anesthetics block morphine-induced increases in serotonin release in rat CNS. Synapse, 18, 307-314.
36. TAO, R. & AUERBACH, S.B. (1995). Involvement of the dorsal raphe but not median raphe nucleus in morphine-induced increases in serotonin release in the rat forebrain. Neuroscience, 68, 553-561.
37. TAO, R. & AUERBACH, S.B. (1996). Differential effect of NMDA on extracellular serotonin in rat midbrain raphe and forebrain sites. J. Neurochem., 66, 1067-1075.
38. TAO, R. & HJORTH, S. (1992). Differences in the in vitro and in vivo 5-hydroxytryptamine extraction performance among three common microdialysis membranes. J. Neurochem., 59, 1778-1785.
39. TORK, I. (1990). Anatomy of the serotonergic system. Ann. New York Acad. Sci., 600, 9-35.
40. WALDMEIER, P.C., WICKI, P., FELDTRAUER, J.J. & BAUMANN, P.A. (1988). Potential involvement of a baclofen-sensitive autoreceptor in the modulation of the release of endogenous GABA from rat brain slices in vitro. Naunyn-Schmiedeberg's Arch. Pharmacol., 337, 289-295.
41. WANG, Q.P., OCHIAI, H. & NAKAI, Y. (1992). GABAergic innervation of serotonergic neurons in the dorsal raphe nucleus of the rat studies by electron microscopy double immunostaining. Brain Res. Bull., 29, 943-948.
42. WANG, R.Y. & AGHAJANIAN, G.K. (1977). Physiological evidence for habenula as major link between forebrain and midbrain raphe. Science, 197, 89-91.
43. WANG, R.Y., GALLAGER, D.W. & AGHAJANIAN, G.K. (1976). Stimulation of pontine reticular formation suppresses firing of serotonergic neurons in the dorsal raphe. Nature, 264, 365-367.
44. WILKINSON, L.O., AUERBACH, S.B. & JACOBS, B.L. (1991). Extracellular serotonin levels change with behavioural state but not with pyrogen-induced hyperthermia. J. Neurosci., 11, 2732-2741.
45. WIRTSHAFTER, D., KLITENICK, M.A. & ASIN, K.E. (1987). Is dopamine involved in the hyperactivity produced by injections of muscimol into the median raphe nucleus? Pharmacol. Biochem. Behav., 30, 577-583.