The molecular cloning and expression of α2,8-sialyltransferase (GD3 synthase) in a rat brain

Journal of Biochemistry

Volumn 120, Issue 5, 1996, Pages 1020-1027

  Watanabe, Yumiko ^a   Nara, Kiyomitsu ^a,b   Takahashi, Hiroshi ^b   Nagai, Yoshitaka ^a,b   Sanai, Yutaka ^a  

^a TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^b MITSUBISHI KASEI INST OF LIFE SCI   (Japan)

Author keywords

Central nervous system; Gangliosides; GD3 synthase; Sialyltransferase

Indexed keywords

COMPLEMENTARY DNA; GANGLIOSIDE GD3; MESSENGER RNA; SIALYLTRANSFERASE;

ANIMAL CELL; ARTICLE; BRAIN CORTEX; BRAIN DEVELOPMENT; CEREBELLUM; DNA LIBRARY; HIPPOCAMPUS; IN SITU HYBRIDIZATION; MOLECULAR CLONING; NONHUMAN; RAT; SPLEEN; THALAMUS;

ANIMALIA; MAMMALIA;

EID: 0029822290     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a021494     Document Type: Article

References (42)

1. Ledeen, R.W. and Yu, R.K. (1982) Gangliosides: Structure, isolation, and analysis. Methods Enzymol. 83, 139-191
2. Yu, R.K. (1994) Development regulation of ganglioside metabolism. Prog. Brain Res. 101, 31-44
3. Rösner, H., Al-Aqtum, M., and Rahmann, H. (1992) Gangliosides and neuronal differentiation. Neurochem. Int. 20, 339-351
4. Yu, R.K., Macala, L.J., Taki, T., Weinfield, H.M., and Yu, F.S. (1988) Developmental changes in ganglioside composition and synthesis in embryonic rat brain. J. Neurochem. 50, 1825-1829
5. Goldman, J.E., Hirano, M., Yu, R.K., and Seyfried, T.N. (1984) GD3 ganglioside is a glycolipid characteristic of immature neuroectodermal cells. J. Neuroimmunol. 7, 179-192
6. Schaal, H., Wille, C., and Wille, W. (1985) Changes of ganglioside pattern during cerebellar development of normal and staggerer mice. J. Neurochem. 45, 544-551
7. Rösner, H. (1983) Developmental expression of gangliosides in vivo and in vitro in Polysialic Acid (Roth, J., Rutishauser, U., and Troy, F.A., eds.) pp. 279-297, Birkhäuser Verlag, Basel
8. Kotani, M., Kawashima, I., Ozawa, H., Ogura, K., Ishizuka, I., Terashima, T., and Tai, T. (1994) Immunohistochemical localization of minor gangliosides in the rat central nervous system. Glycobiology 4, 855-865
9. Kawai, K., Mori, M., Watarai, S., and Yasuda, T. (1994) Immunohistochemical demonstration of ganglioside GD3 in the central nervous system. Neurosci. Res. 19, 119-124
10. Kawai, K., Kuroda, S., Watarai, S., and Takahashi, H. (1994) Developmental profile of ganglioside GD3 in the central nervous system: An immunohistochemical study in the rat. Neurosci. Res. 19, 77-82
11. Cheresh, D.A., Pierschbacher, M.D., Herzig, M.A., and Mujoo, K. (1986) Disialogangliosides GD2 and GD3 are involved in the attachment of human melanoma and neuroblastoma cells to extracellular matrix proteins. J. Cell Biol. 102, 688-696
12. Sariola, H., Aufderheide, E., Bernhard, H., Henke, F.S., Dippold, W., and Ekblom, P. (1988) Antibodies to cell surface ganglioside GD3 perturb inductive epithelial-mesenchymal interactions. Cell 54, 235-245
13. van Echten, G. and Sandhoff, K. (1993) Ganglioside metabolism. Enzymology, topology, and regulation. J. Biol. Chem. 268, 5341-5344
14. Schüz, H.R., Ullmer, E., Prinz, C., and Decker, K. (1989) The activity of GD3 synthase modulates the ganglioside pattern in rat liver. Eur. J. Biochem. 186, 327-330
15. Nara, K., Watanabe, Y., Maruyama, K., Kasahara, K., Nagai, Y., and Sanai, Y. (1994) Expression cloning of a CMP-NeuAc: NeuAcα2-3Galβ1-4Glcβ1-1′Cer α2,8-sialyltransferase (GD3 synthase) from human melanoma cell. Proc. Natl. Acad. Sci. USA 91, 7952-7956
16. Sasaki, K., Kurata, K., Kojima, N., Kurosawa, N., Ohta, S., Hanai, N., Tsuji, S., and Nishi, T. (1994) Expression cloning of a GM3-specific α-2,8-sialyltransferase (GD3 synthase). J. Biol. Chem. 269, 15950-15956
17. Haraguchi, M., Yamashiro, S., Yamamoto, A., Furukawa, K., Takamiya, K., Lloyd, K.O., Shiku, H., and Furukawa, K. (1994) Isolation of GD3 synthase gene by expression cloning of GM3 α-2,8-sialyltransferase cDNA using anti-GD2 monoclonal antibody. Proc. Natl. Acad. Sci. USA 91, 10455-10459
18. Matsuda, Y., Nara, K., Watanabe, Y., Saito, T., and Sanai, Y. (1996) Chromosome mapping of the GD3 synthase gene (SIAT8) in human and mouse. Genomics 32, 137-139
19. Wen, D.X., Livingston, B.D., Medzihradszky, K.F., Kelm, S., Burlingame, A.L., and Paulson, J.C. (1992) Primary structure of Gal β1,3(4)GlcNAc α2,3-sialyltransferase determined by mass spectrometry sequence analysis and molecular cloning. Evidence for a protein motif in the sialyltransferase gene family. J. Biol. Chem. 267, 21011-21019
20. Sanchez-Lopez, R., Nicholson, R., Gesnel, M.C., Matrisian, L.M., and Breathnach, R. (1988) Structure-function relationships in the collagenase family member transin. J. Biol. Chem. 263, 11892-11899
21. Shirasawa, T., Sakamoto, K., Akashi, T., Takahashi, H., and Kawashima, A. (1992) Nucleotide sequence of rat elongation factor-1α cDNA. Nucleic Acid Res. 20, 909
22. Kasahara, K., Guo, L., Nagai, Y., and Sanai, Y. (1994) Enzymatic assay of glycosphingolipid sialyltransferase using reverse-phase thin-layer chromatography. Anal. Biochem. 218, 224-226
23. Simmons, D.M., Arriza, J.L., and Swanson, L.W. (1989) A complete protocol for in situ hybridization of messenger RNAs in brain and other tissues with radiolabeled single-stranded RNA probes. J. Histotechnol. 12, 169-181
24. Nara, K., Watanabe, Y., Kawashima, I., Tai, T., Nagai, Y., and Sanai, Y. (1996) Acceptor substrate specificity of a cloned GD3 synthase that catalyzes the biosynthesis of both GD3 and GD1c/GT1a/GQ1b. Eur. J. Biochem. 238, 647-652
25. Nakayama, J., Fukuda, M.N., Hirabayashi, Y., Kanamori, A., Sasaki, K., Nishi, T., and Fukuda, M. (1996) Expression cloning of a human GT3 synthase, GD3 and GT3 are synthesized by a single enzyme. J. Biol. Chem. 271, 3684-3691
26. Tsuji, S., Arita, M., and Nagai, Y. (1983) GQ1b, a bioactive ganglioside that exhibits novel nerve growth factor (NGF)-like activities in the two neuroblastoma cell lines. J. Biochem. 94, 303-306
27. Kojima, N., Kurosawa, N., Nishi, T., Hanai, N., and Tsuji, S. (1994) Induction of cholinergic differentiation with neurite sprouting by de novo biosynthesis and expression of GD3 and b-series gangliosides in Neuro2a cells. J. Biol. Chem. 269, 30451-30456
28. Yamamoto, A., Haraguchi, M., Yamashiro, S., Fukumoto, S., Furukawa, K., Takamiya, K., Atsuta, M., Shiku, H., and Furukawa, K. (1996) Heterogeneity in the expression pattern of two ganglioside synthase genes during mouse brain development. J. Neurochem. 66, 26-34
29. Nakamura, K., Hashimoto, Y., Yamakawa, T., and Suzuki, A. (1988) Genetic polymorphism of ganglioside expression in mouse organs. J. Biochem. 103, 201-208
30. Welte, K., Miller, G., Chapman, P.B., Yuasa, H., Natoli, E., Kunicka, J.E., Cordon, C.C., Buhrer, C., Old, L.J., and Houghton, A.N. (1987) Stimulation of T lymphocyte proliferation by monoclonal antibodies against GD3 ganglioside. J. Immunol. 139, 1763-1771
31. Irwin, L.N., Michael, D.B., and Irwin, C.C. (1980) Ganglioside patterns of fetal rat and mouse brain. J. Neurochem. 34, 1527-1530
32. Chou, K.H., Nolan, C.E., and Jungalwala, F.B. (1982) Composition and metabolism of gangliosides in rat peripheral nervous system during development. J. Neurochem. 39, 1547-1558
33. Rösner, H. (1982) Ganglioside changes in the chicken optic lobes as biochemical indicators of brain development and maturation. Brain Res. 236, 49-61
34. Dreyfus, H., Urban, P.F., Edel, H.S., and Mandel, P. (1975) Developmental patterns of gangliosides and of phospholipids in chick retina and brain. J. Neurochem. 25, 245-250
35. Irwin, L.N. and Irwin, C.C. (1979) Phylogenetic and regional variations in brain gangliosides of tetrapods. Comp. Biochem. Physiol. B: Comp. Biochem. 64, 121-123
36. Rösner, H. (1980) A new thin-layer Chromatographic approach for separation of multisialogangliosides. Novel gangliosides fractions in the embryonic chicken brain. Anal. Biochem. 109, 437-442
37. Graus, F., Cordon, C.C., Houghton, A.N., Melamed, M.R., and Old, L.J. (1984) Distribution of the ganglioside GD3 in the human nervous system detected by R24 mouse monoclonal antibody. Brain Res. 324, 190-194
38. Reynolds, R. and Wilkin, G.P. (1988) Expression of GD3 ganglioside by developing rat cerebellar Purkinje cells in situ. J. Neurosci. Res. 20, 311-319
39. Seyfried, T.M., Yu, R.K., Miyazawa, N., and Lai, Y.L. (1982) Retinal gangliosides in RCS mutant rats. J. Neurochem. 39, 277-279
40. Daniotti, J.L., Landa, C.A., Rösner, H., and Maccioni, H.J.F. (1992) Adult rat retina interneurons synthesize GD3: GD3 expression by these cells is regulated by cell-cell interactions. J. Neurochem. 59, 107-117
41. Yamamoto, A., Yamashiro, S., Fukumoto, S., Haraguchi, M., Atsuta, M., Shiku, H., and Furukawa, K. (1996) Site restricted and neuron dominant expression of α2,8sialyltransferase gene in the adult mouse brain and retina. Glycoconjugate J. 13, 471-480
42. Svennerholm, L. (1963) Chromatographic separation of human brain gangliosides. J. Neurochem. 10, 613-623