메뉴 건너뛰기




Volumn 10, Issue 6, 1996, Pages 851-858

Review article: Methotrexate in gastroenterology - Dangerous villain or simply misunderstood?

Author keywords

[No Author keywords available]

Indexed keywords

METHOTREXATE;

EID: 0029821008     PISSN: 02692813     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2036.1996.70244000.x     Document Type: Article
Times cited : (24)

References (64)
  • 1
    • 0014411308 scopus 로고
    • Cirrhosis associated with methotrexate treatment of psoriasis
    • Coe RO, Bull FE. Cirrhosis associated with methotrexate treatment of psoriasis. J Am Med Assoc 1968; 206: 1515-20.
    • (1968) J Am Med Assoc , vol.206 , pp. 1515-1520
    • Coe, R.O.1    Bull, F.E.2
  • 2
    • 0015845084 scopus 로고
    • Synthesis and biological evaluation of poly-glutamyl derivatives of methotrexate
    • Nair MG, Baugh CM. Synthesis and biological evaluation of poly-glutamyl derivatives of methotrexate. Biochemistry 1973; 12: 3923-7.
    • (1973) Biochemistry , vol.12 , pp. 3923-3927
    • Nair, M.G.1    Baugh, C.M.2
  • 3
    • 0022547880 scopus 로고
    • Methotrexate metabolism analysis in blood and liver of rheumatoid arthritis patients
    • Kremer JM, Galivan J, Streckfuss A, et al. Methotrexate metabolism analysis in blood and liver of rheumatoid arthritis patients. Arthritis Rheum 1986; 29: 832-5.
    • (1986) Arthritis Rheum , vol.29 , pp. 832-835
    • Kremer, J.M.1    Galivan, J.2    Streckfuss, A.3
  • 4
    • 0023481797 scopus 로고
    • Transient acute hepatotoxicity of high dose methotrexate treatment during childhood
    • Weber BI, Tanyer G, Poplack DG, et al Transient acute hepatotoxicity of high dose methotrexate treatment during childhood. Natl Cancer Inst Monograph 1987; 5: 207-12.
    • (1987) Natl Cancer Inst Monograph , vol.5 , pp. 207-212
    • Weber, B.I.1    Tanyer, G.2    Poplack, D.G.3
  • 5
    • 0017505482 scopus 로고
    • Methotrexate hepatotoxicity in children with leukaemia
    • Mclntosh S, Davidson DC, O'Brien RT, et al. Methotrexate hepatotoxicity in children with leukaemia. J Pediatr 1977; 90: 1019-21.
    • (1977) J Pediatr , vol.90 , pp. 1019-1021
    • Mclntosh, S.1    Davidson, D.C.2    O'Brien, R.T.3
  • 6
    • 0001395239 scopus 로고
    • Hepatic fibrosis in children with acute leukaemia: A complication of therapy
    • Hutter RVP, Shipkey FH, Tam CTC, et al. Hepatic fibrosis in children with acute leukaemia: A complication of therapy. Cancer 1960; 13: 288-307.
    • (1960) Cancer , vol.13 , pp. 288-307
    • Hutter, R.V.P.1    Shipkey, F.H.2    Tam, C.T.C.3
  • 7
    • 0025678922 scopus 로고
    • Aspirin, hydroxychloroquine, and hepatic enzyme abnormalities with methotrexate in rheumatoid arthritis
    • Fries JF, Singh G. Lenert L, et al. Aspirin, hydroxychloroquine, and hepatic enzyme abnormalities with methotrexate in rheumatoid arthritis. Arthritis Rheum 1990; 33: 1611-9.
    • (1990) Arthritis Rheum , vol.33 , pp. 1611-1619
    • Fries, J.F.1    Singh, G.2    Lenert, L.3
  • 8
    • 0017877011 scopus 로고
    • Effect of pleural effusion on high dose methotrexate kinetics
    • Evans WE, Pratt CB. Effect of pleural effusion on high dose methotrexate kinetics. Clin Pharmacol Ther 1987; 23: 68-72.
    • (1987) Clin Pharmacol Ther , vol.23 , pp. 68-72
    • Evans, W.E.1    Pratt, C.B.2
  • 9
    • 0023143528 scopus 로고
    • Pulmonary disease during the treatment of rheumatoid arthritis with low dose pulse methotrexate
    • Carson CW, Cannon GW, Egger MJ, et al. Pulmonary disease during the treatment of rheumatoid arthritis with low dose pulse methotrexate. Semin Arthritis Rheum 1987; 21: 186-195.
    • (1987) Semin Arthritis Rheum , vol.21 , pp. 186-195
    • Carson, C.W.1    Cannon, G.W.2    Egger, M.J.3
  • 10
    • 0027310972 scopus 로고
    • Reversible lymphoma associated with Epstein-Barr virus occurring during methotrexate therapy for rheumatoid arthritis and dermatomyositis
    • Kamel OW, Van de Rijn M, Weisslm, et al. Reversible lymphoma associated with Epstein-Barr virus occurring during methotrexate therapy for rheumatoid arthritis and dermatomyositis. N Engl J Med 1993; 328: 1317-21.
    • (1993) N Engl J Med , vol.328 , pp. 1317-1321
    • Kamel, O.W.1    Van De Rijn, M.2    Weisslm3
  • 11
    • 0023633197 scopus 로고
    • Hepatocellular carcinoma in a long term survivor of acute lymphocytic leukaemia
    • Fried M, Kalro J, Ilardi C, et al. Hepatocellular carcinoma in a long term survivor of acute lymphocytic leukaemia. Cancer 1987; 60: 2548-52.
    • (1987) Cancer , vol.60 , pp. 2548-2552
    • Fried, M.1    Kalro, J.2    Ilardi, C.3
  • 12
    • 0017608288 scopus 로고
    • Hepatoma in a child with methotrexate induced hepatic fibrosis
    • Ruymann FB, Mosijczuk A, Sayers RJ. Hepatoma in a child with methotrexate induced hepatic fibrosis. J Am Med Assoc 1977; 238: 2631-3.
    • (1977) J Am Med Assoc , vol.238 , pp. 2631-2633
    • Ruymann, F.B.1    Mosijczuk, A.2    Sayers, R.J.3
  • 13
    • 0017646050 scopus 로고
    • Liver biopsies from psoriatics related to methotrexate therapy
    • Nyfors A. Liver biopsies from psoriatics related to methotrexate therapy. Acta Pathol Microbiol Scand Sect A 1977; 85: 511-8.
    • (1977) Acta Pathol Microbiol Scand Sect A , vol.85 , pp. 511-518
    • Nyfors, A.1
  • 15
    • 0018837419 scopus 로고
    • Methotrexate induced liver cirrhosis: Studies including serial liver biopsies during continued treatment
    • Zachariae H, Kragbelle K, Sogaard H. Methotrexate induced liver cirrhosis: Studies including serial liver biopsies during continued treatment. Br J Dermatol 1980; 102: 407-12.
    • (1980) Br J Dermatol , vol.102 , pp. 407-412
    • Zachariae, H.1    Kragbelle, K.2    Sogaard, H.3
  • 16
    • 0027523650 scopus 로고
    • Determinants of serious liver disease among patients receiving low dose methotrexate for rheumatoid arthritis
    • Walker Am, Funch D, Dreyer NA, et al. Determinants of serious liver disease among patients receiving low dose methotrexate for rheumatoid arthritis. Arthritís Rheum 1993; 36: 329-35.
    • (1993) Arthritís Rheum , vol.36 , pp. 329-335
    • Walker, Am.1    Funch, D.2    Dreyer, N.A.3
  • 18
    • 0024386009 scopus 로고
    • Acute, reversible hepatic failure associated with methotrexate treatment of rheumatoid arthritis
    • Clegg DO, Furst DE, Tolman KG, et al. Acute, reversible hepatic failure associated with methotrexate treatment of rheumatoid arthritis. J Rheumatol 1989; 16: 1123-6.
    • (1989) J Rheumatol , vol.16 , pp. 1123-1126
    • Clegg, D.O.1    Furst, D.E.2    Tolman, K.G.3
  • 19
    • 0025287127 scopus 로고
    • Hepatitis with bridging fibrosis and reversible hepatic insufficiency in a woman with rheumatoid arthritis taking methotrexate
    • Kujala GA, Shamma'a JM, Chang WL, et al. Hepatitis with bridging fibrosis and reversible hepatic insufficiency in a woman with rheumatoid arthritis taking methotrexate. Arthritis Rheum 1990; 33: 1037-41.
    • (1990) Arthritis Rheum , vol.33 , pp. 1037-1041
    • Kujala, G.A.1    Shamma'a, J.M.2    Chang, W.L.3
  • 20
    • 0025266211 scopus 로고
    • Methotrexate induced cirrhosis requiring liver transplantation in three patients with psoriasis
    • Gilbert SC, Klintmalm G, Menter A, et al. Methotrexate induced cirrhosis requiring liver transplantation in three patients with psoriasis. Arch Intern Med 1990; 150: 889-91.
    • (1990) Arch Intern Med , vol.150 , pp. 889-891
    • Gilbert, S.C.1    Klintmalm, G.2    Menter, A.3
  • 21
    • 76549239323 scopus 로고
    • Therapeutic suppression of tissue reactivity II. Effect of aminopterin in rheumatoid arthritis and psoriasis
    • Gubner R, August S, Ginsberg V. Therapeutic suppression of tissue reactivity II. Effect of aminopterin in rheumatoid arthritis and psoriasis. Am J Med Sci 1951; 221: 176-82.
    • (1951) Am J Med Sci , vol.221 , pp. 176-182
    • Gubner, R.1    August, S.2    Ginsberg, V.3
  • 22
    • 0025289490 scopus 로고
    • Methotrexate side effect
    • Zachariae H. Methotrexate side effect. Br J Dermatol 1990; 122 (Suppl. 36): 127-33.
    • (1990) Br J Dermatol , vol.122 , Issue.36 SUPPL. , pp. 127-133
    • Zachariae, H.1
  • 23
    • 0014602935 scopus 로고
    • Cirrhosis following methotrexate administration for psoriasis
    • Epstein EH, Croft JR. Cirrhosis following methotrexate administration for psoriasis. Arch Dermatol 1969; 100: 531-4.
    • (1969) Arch Dermatol , vol.100 , pp. 531-534
    • Epstein, E.H.1    Croft, J.R.2
  • 24
    • 0014602724 scopus 로고
    • Cirrhosis caused by methotrexate in the treatment of psoriasis
    • Muller SA, Farrow GM, Martalock DL. Cirrhosis caused by methotrexate in the treatment of psoriasis. Arch Dermatol 1969; 100: 523-30.
    • (1969) Arch Dermatol , vol.100 , pp. 523-530
    • Muller, S.A.1    Farrow, G.M.2    Martalock, D.L.3
  • 25
    • 0017274306 scopus 로고
    • Liver biopsies from psoriatics related to methotrexate therapy: Findings in 123 consecutive non-methotrexate treated patients
    • Nyfors A, Poulsen H. Liver biopsies from psoriatics related to methotrexate therapy: Findings in 123 consecutive non-methotrexate treated patients. Acta Pathol Microbiol Scand Sect A 1976; 84: 253-61.
    • (1976) Acta Pathol Microbiol Scand Sect A , vol.84 , pp. 253-261
    • Nyfors, A.1    Poulsen, H.2
  • 26
    • 0019974635 scopus 로고
    • Complications in methotrexate treatment of psoriasis with particular reference to liver fibrosis
    • Ashton RE, Millward-Sadler GH, White JE. Complications in methotrexate treatment of psoriasis with particular reference to liver fibrosis. J Invest Dermatol 1982; 79: 229-32.
    • (1982) J Invest Dermatol , vol.79 , pp. 229-232
    • Ashton, R.E.1    Millward-Sadler, G.H.2    White, J.E.3
  • 27
    • 0018906122 scopus 로고
    • Methotrexate hepatotoxicity in psoríasis. Consideration of liver biopsies at regular intervals
    • Robinson AK, Baughman RD, Auerbach R, et al. Methotrexate hepatotoxicity in psoríasis. Consideration of liver biopsies at regular intervals. Arch Dermatol 1980; 116: 413-5.
    • (1980) Arch Dermatol , vol.116 , pp. 413-415
    • Robinson, A.K.1    Baughman, R.D.2    Auerbach, R.3
  • 28
    • 0024444047 scopus 로고
    • The role of liver biopsies in psoriatic patients receiving long term methotrexate treatment. Improvement in liver abnormalities after cessation of treatment
    • Newman M, Auerbach R, Feiner H, et al. The role of liver biopsies in psoriatic patients receiving long term methotrexate treatment. Improvement in liver abnormalities after cessation of treatment. Arch Dermatol 1989; 125: 1218-24.
    • (1989) Arch Dermatol , vol.125 , pp. 1218-1224
    • Newman, M.1    Auerbach, R.2    Feiner, H.3
  • 30
    • 0016169437 scopus 로고
    • Effects of methotrexate on the liver in psoriasis
    • Reese LT, Grisham JW, Aach RD, et al. Effects of methotrexate on the liver in psoriasis. J Invest Dermatol 1974; 62: 597-602.
    • (1974) J Invest Dermatol , vol.62 , pp. 597-602
    • Reese, L.T.1    Grisham, J.W.2    Aach, R.D.3
  • 31
    • 0023263542 scopus 로고
    • Methotrexate-induced liver cirrhosis
    • Zachariae H, Søgaard H. Methotrexate-induced liver cirrhosis. Dermatologica 1987; 175: 178-82.
    • (1987) Dermatologica , vol.175 , pp. 178-182
    • Zachariae, H.1    Søgaard, H.2
  • 32
    • 0026052187 scopus 로고
    • Guidelines for management of patients with psoriasis
    • Workshop of the Research Unit of the Royal College of Physicians of London; Department of Dermatology, University of Glasgow; British Association of Dermatogists. Guidelines for management of patients with psoriasis. Br Med J 1991; 303: 829-35.
    • (1991) Br Med J , vol.303 , pp. 829-835
  • 33
    • 0025832517 scopus 로고
    • Methotrexate in rheumatoid arthritis: Effects on disease activity in a multicentre prospective study
    • Weinblatt ME, Kaplan H, Germain BF, et al. Methotrexate in rheumatoid arthritis: effects on disease activity in a multicentre prospective study. J Rheumatol 1991; 18: 334-8.
    • (1991) J Rheumatol , vol.18 , pp. 334-338
    • Weinblatt, M.E.1    Kaplan, H.2    Germain, B.F.3
  • 34
    • 0021951021 scopus 로고
    • Interleukin-2 rheumatoid arthritis: Production of and response to interleukin-2 in rheumatoid synovial fluid, synovial tissue and peripheral blood
    • Combe B, Pope RM. Fischbach M, et al. Interleukin-2 rheumatoid arthritis: production of and response to interleukin-2 in rheumatoid synovial fluid, synovial tissue and peripheral blood. Clin Exp Immunol 1985; 59: 520-8.
    • (1985) Clin Exp Immunol , vol.59 , pp. 520-528
    • Combe, B.1    Pope, R.M.2    Fischbach, M.3
  • 35
    • 0023853643 scopus 로고
    • Long term prospective trial of low dose methotrexate in rheumatoid arthritis
    • Weinblatt ME, Trentham DE, Fraser DA, et al Long term prospective trial of low dose methotrexate in rheumatoid arthritis. Arthritis Rheum 1988; 31: 167-75.
    • (1988) Arthritis Rheum , vol.31 , pp. 167-175
    • Weinblatt, M.E.1    Trentham, D.E.2    Fraser, D.A.3
  • 36
    • 0023196267 scopus 로고
    • Immunologic studies of rheumatoid arthritis patients treated with methotrexate
    • Olsen NJ, Callahan LF, Pincus T. Immunologic studies of rheumatoid arthritis patients treated with methotrexate. Arthritis Rheum 1987; 30: 481-8.
    • (1987) Arthritis Rheum , vol.30 , pp. 481-488
    • Olsen, N.J.1    Callahan, L.F.2    Pincus, T.3
  • 37
    • 0018835239 scopus 로고
    • The effect of methotrexate and hydroxyurea on neutrophil chemotaxis
    • Cream JJ, Pole DS. The effect of methotrexate and hydroxyurea on neutrophil chemotaxis. Br J Dermatol 1980; 102: 557-63.
    • (1980) Br J Dermatol , vol.102 , pp. 557-563
    • Cream, J.J.1    Pole, D.S.2
  • 38
    • 0023255416 scopus 로고
    • Methotrexate in rheumatoid arthritis
    • Health and Public Policy Committee, American College of Physicians. Methotrexate in rheumatoid arthritis. Ann Intern Med 1987; 107: 418-9.
    • (1987) Ann Intern Med , vol.107 , pp. 418-419
  • 39
    • 0028215036 scopus 로고
    • Methotrexate for rheumatoid arthritis. Suggested guidelines for monitoring liver toxicity
    • Kremer JM, Alarcon GS, Lightfoot RW, et al. Methotrexate for rheumatoid arthritis. Suggested guidelines for monitoring liver toxicity. Arthritis Rheum 1994; 37: 316-28.
    • (1994) Arthritis Rheum , vol.37 , pp. 316-328
    • Kremer, J.M.1    Alarcon, G.S.2    Lightfoot, R.W.3
  • 40
    • 0024239180 scopus 로고
    • Hepatic ultra-structure after methotrexate therapy for rheumatoid arthritis
    • Bjorkman DJ, Hammond EH, Lee RG, et al. Hepatic ultra-structure after methotrexate therapy for rheumatoid arthritis. Arthritis Rheum 1988; 31: 1465-72.
    • (1988) Arthritis Rheum , vol.31 , pp. 1465-1472
    • Bjorkman, D.J.1    Hammond, E.H.2    Lee, R.G.3
  • 41
    • 0027507819 scopus 로고
    • The effect of long term methotrexate therapy on hepatic fibrosis in rheumatoid arthritis
    • Bjorkman DJ, Boschert M, Tolman KG, et al. The effect of long term methotrexate therapy on hepatic fibrosis in rheumatoid arthritis. Arthritis Rheum 1993; 36: 1697-1701.
    • (1993) Arthritis Rheum , vol.36 , pp. 1697-1701
    • Bjorkman, D.J.1    Boschert, M.2    Tolman, K.G.3
  • 42
    • 0026315404 scopus 로고
    • Methotrexate and histologic hepatic abnormalities: A meta-analysis
    • Whiting-O'Keefe QE, Fye KH, Sack KD, Methotrexate and histologic hepatic abnormalities: a meta-analysis. Am J Med 1991; 90: 711-6.
    • (1991) Am J Med , vol.90 , pp. 711-716
    • Whiting-O'Keefe, Q.E.1    Fye, K.H.2    Sack, K.D.3
  • 43
    • 0024504349 scopus 로고
    • Liver histology in rheumatoid arthritis patients receiving long term methotrexate therapy
    • Kremer JM. Lee RG, Tolman G. Liver histology in rheumatoid arthritis patients receiving long term methotrexate therapy. Arthritis Rheum 1989; 32: 121-7.
    • (1989) Arthritis Rheum , vol.32 , pp. 121-127
    • Kremer, J.M.1    Lee, R.G.2    Tolman, G.3
  • 44
    • 10544244911 scopus 로고
    • Long term prospective sequential biopsies in patients with rheumatoid arthritis on wekly oral methotrexate
    • Abstract
    • Kremer JM. Long term prospective sequential biopsies in patients with rheumatoid arthritis on wekly oral methotrexate. Arthritis Rheum 1990; 33 (Suppl. 9): S40. (Abstract.)
    • (1990) Arthritis Rheum , vol.33 , Issue.9 SUPPL.
    • Kremer, J.M.1
  • 45
    • 10544251343 scopus 로고
    • Liver histology in methotrexate treated rheumatoid arthritis patients: Repeat biopsies after the development of fibrosis
    • Aponte J, Petrelli M. Liver histology in methotrexate treated rheumatoid arthritis patients: repeat biopsies after the development of fibrosis. Arthritis Rheum 1988; 31: S116.
    • (1988) Arthritis Rheum , vol.31
    • Aponte, J.1    Petrelli, M.2
  • 46
    • 0026537794 scopus 로고
    • Long term prospective study of methotrexate in the treatment of rheumatoid arthritis: 84 month update
    • Weinblatt ME, Weissman BN, Holdsworth DE, et al. Long term prospective study of methotrexate in the treatment of rheumatoid arthritis: 84 month update. Arthritis Rheum 1992; 35: 129-37.
    • (1992) Arthritis Rheum , vol.35 , pp. 129-137
    • Weinblatt, M.E.1    Weissman, B.N.2    Holdsworth, D.E.3
  • 47
    • 0026550604 scopus 로고
    • A prospective analysis of liver biopsies in rheumatoid arthritis patients receiving long term methotrexate therapy
    • Tishler M, Caspi D, Halperin Z, et al. A prospective analysis of liver biopsies in rheumatoid arthritis patients receiving long term methotrexate therapy. Rheumatol Int 1992; 12 (1): 39-41.
    • (1992) Rheumatol Int , vol.12 , Issue.1 , pp. 39-41
    • Tishler, M.1    Caspi, D.2    Halperin, Z.3
  • 48
    • 0024405598 scopus 로고
    • Prospective analysis of liver biopsies before and after methotrexate therapy in rheumatoid patients
    • Brick JE, Moreland LW, Al-Kawas F, et al. Prospective analysis of liver biopsies before and after methotrexate therapy in rheumatoid patients. Semin Arthritis Rheum 1989; 19: 31-44.
    • (1989) Semin Arthritis Rheum , vol.19 , pp. 31-44
    • Brick, J.E.1    Moreland, L.W.2    Al-Kawas, F.3
  • 49
    • 0027996053 scopus 로고
    • Cirrhosis in patients with rheumatoid arthritis receiving low dose methotrexate
    • Chandran G, Ahern MJ, Hall PM, et al. Cirrhosis in patients with rheumatoid arthritis receiving low dose methotrexate. Br J Rheumatol 1994; 33: 981-4.
    • (1994) Br J Rheumatol , vol.33 , pp. 981-984
    • Chandran, G.1    Ahern, M.J.2    Hall, P.M.3
  • 50
    • 0026576192 scopus 로고
    • Clinical liver disease in patients with rheumatoid arthritis taking methotrexate
    • Phillips CA, Cera PJ, Mangan TF, et al. Clinical liver disease in patients with rheumatoid arthritis taking methotrexate. J Rheumatol 1992; 19: 229-33.
    • (1992) J Rheumatol , vol.19 , pp. 229-233
    • Phillips, C.A.1    Cera, P.J.2    Mangan, T.F.3
  • 51
    • 0028965107 scopus 로고
    • The cost-effectiveness of liver biopsy in rheumatoid arthritis patients treated with methotrexate
    • Bergquist SR, Felson DT, Prashker MJ, et al. The cost-effectiveness of liver biopsy in rheumatoid arthritis patients treated with methotrexate. Arthritis Rheum 1995; 38: 326-33.
    • (1995) Arthritis Rheum , vol.38 , pp. 326-333
    • Bergquist, S.R.1    Felson, D.T.2    Prashker, M.J.3
  • 52
    • 0023735825 scopus 로고
    • Primary biliary cirrhosis treated with low-dose oral pulse methotrexate
    • Kaplan MM, Knox TA, Arora S. Primary biliary cirrhosis treated with low-dose oral pulse methotrexate. Ann Intern Med 1988; 109: 429-31.
    • (1988) Ann Intern Med , vol.109 , pp. 429-431
    • Kaplan, M.M.1    Knox, T.A.2    Arora, S.3
  • 54
    • 0026014151 scopus 로고
    • Treatment of primary cirrhosis with low-dose weekly methotrexate
    • Kaplan MM, Knox TA. Treatment of primary cirrhosis with low-dose weekly methotrexate. Gastroenterology 1991; 101: 1332-8.
    • (1991) Gastroenterology , vol.101 , pp. 1332-1338
    • Kaplan, M.M.1    Knox, T.A.2
  • 55
    • 10544248876 scopus 로고
    • Oral methotrexate for primary biliary cirrhosis: Preliminary report
    • Abstract
    • Bergasa N, Hoofnagle J, Axiotis C, et al. Oral methotrexate for primary biliary cirrhosis: preliminary report. Gastroenterology 1991; 100: A720. (Abstract.)
    • (1991) Gastroenterology , vol.100
    • Bergasa, N.1    Hoofnagle, J.2    Axiotis, C.3
  • 56
    • 0027190525 scopus 로고
    • Positive responses to methotrexate and ursodeoxycholic acid in patients with primary biliary cirrhosis responding in sufficiently to ursodeoxycholic acid alone
    • Buscher HP, Zietzschmann Y, Gerok W. Positive responses to methotrexate and ursodeoxycholic acid in patients with primary biliary cirrhosis responding in sufficiently to ursodeoxycholic acid alone. J Hepatol 1993; 18: 9-14.
    • (1993) J Hepatol , vol.18 , pp. 9-14
    • Buscher, H.P.1    Zietzschmann, Y.2    Gerok, W.3
  • 57
    • 10544230938 scopus 로고    scopus 로고
    • Effect of long term, low-dose methotrexate therapy for primary biliary cirrhosis on liver biopsy morphology
    • Abstract
    • Schaffner F, Bach N, Thung SN. Effect of long term, low-dose methotrexate therapy for primary biliary cirrhosis on liver biopsy morphology. Hepatology 1996; 23: 230 (Abstract).
    • (1996) Hepatology , vol.23 , pp. 230
    • Schaffner, F.1    Bach, N.2    Thung, S.N.3
  • 58
    • 10544226072 scopus 로고
    • Methotrexate after five years in primary biliary cirrhosis
    • Abstract
    • Kaplan M. Methotrexate after five years in primary biliary cirrhosis. Gastroenterology 1991; 102: A829. (Abstract.)
    • (1991) Gastroenterology , vol.102
    • Kaplan, M.1
  • 59
    • 0026576716 scopus 로고
    • Methotrexate for biliary cirrhosis
    • Letter
    • Kaplan M, Knox T. Methotrexate for biliary cirrhosis. Gastroenterology 1992; 102: 1824. (Letter.)
    • (1992) Gastroenterology , vol.102 , pp. 1824
    • Kaplan, M.1    Knox, T.2
  • 60
    • 0024517127 scopus 로고
    • Methotrexate induces clinical and histologic remission in patients with reflactory inflammatory bowel disease
    • Kozarek RA. Patterson DJ, Gelfand MD, et al. Methotrexate induces clinical and histologic remission in patients with reflactory inflammatory bowel disease. Ann Intern Med 1989; 110: 353-6.
    • (1989) Ann Intern Med , vol.110 , pp. 353-356
    • Kozarek, R.A.1    Patterson, D.J.2    Gelfand, M.D.3
  • 61
    • 0028899859 scopus 로고
    • Methotrexate for the treatment of Crohn's Disease
    • Feagan BG, Rochon J, Fedorak RN, et al. Methotrexate for the treatment of Crohn's Disease. N Engl J Med 1995; 332: 292-7.
    • (1995) N Engl J Med , vol.332 , pp. 292-297
    • Feagan, B.G.1    Rochon, J.2    Fedorak, R.N.3
  • 62
    • 0000141523 scopus 로고    scopus 로고
    • The role of methrexate therapy in the management of patients with cyclosporin A-resistant inflammatory bowel disease
    • Abstract
    • Alvarez F, Dullavis J, O'Brien J. The role of methrexate therapy in the management of patients with cyclosporin A-resistant inflammatory bowel disease. Gastroenterology 1996; 110: A853. (Abstract.)
    • (1996) Gastroenterology , vol.110
    • Alvarez, F.1    Dullavis, J.2    O'Brien, J.3
  • 63
    • 0000401571 scopus 로고    scopus 로고
    • Methotrexate therapy in children with severe Crohn's Disease: Preliminary results
    • Abstract
    • Gohkale R, Kirschner BS. Methotrexate therapy in children with severe Crohn's Disease: preliminary results. Gastroenterology 1996; 110: A916. (Abstract.)
    • (1996) Gastroenterology , vol.110
    • Gohkale, R.1    Kirschner, B.S.2
  • 64
    • 0001303599 scopus 로고    scopus 로고
    • Methotrexate in Crohn's Disease: Long term efficacy and toxicity
    • Abstract
    • Zenjari T, Lemann M, Mesnard B, et al. Methotrexate in Crohn's Disease: long term efficacy and toxicity. Gastroenterology 1996; 110: A1053. (Abstract.)
    • (1996) Gastroenterology , vol.110
    • Zenjari, T.1    Lemann, M.2    Mesnard, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.