Synthesis of novel thiazolo[4,5-d]pyrimidine derivatives for antimicrobial, anti-HIV and anticancer investigation

Pharmazie

Volumn 51, Issue 12, 1996, Pages 927-931

  Rida, S M ^a   Habib, N S ^a   Badawey, E A M ^a   Fahmy, H T Y ^a   Ghozlan, H A ^b  

^a Alexandria University Faculty of Pharmacy   (Egypt)

^b Alexandria University Faculty Of Science   (Egypt)

Author keywords

[No Author keywords available]

Indexed keywords

AMPICILLIN; ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; CLOTRIMAZOLE; PYRIMIDINE DERIVATIVE; STREPTOMYCIN; THIAZOLE DERIVATIVE; THIAZOLO[4,5 D]PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIFUNGAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIVIRAL ACTIVITY; ARTICLE; ASPERGILLUS NIGER; CONTROLLED STUDY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MINIMUM INHIBITORY CONCENTRATION; PENICILLIUM; STRUCTURE ACTIVITY RELATION; TUMOR CELL;

ANTI-BACTERIAL AGENTS; ANTI-HIV AGENTS; ANTI-INFECTIVE AGENTS; ANTIFUNGAL AGENTS; ANTINEOPLASTIC AGENTS; BACTERIA; DRUG SCREENING ASSAYS, ANTITUMOR; FUNGI; HIV-1; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MICROBIAL SENSITIVITY TESTS; PYRIMIDINES; THIAZOLES; TUMOR CELLS, CULTURED;

EID: 0029820742     PISSN: 00317144     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Nagahara, K.; Anderson, J. D.; Kinni, G. D.; Dalley, N. K.; Larson, S. B.; Smee, D. F.; Jin, A.; Sharma, B. S.; Jolley, W. B.; et al.: J. Med. Chem. 33, 407 (1990)
2. Smee, D. F.; Alaghamandan, H. A.; Bartlett, M. L.; Robins, R. K.: Antiviral Chem. 1, 47 (1990); C.A. 113, 184255 t (1990)
3. Smee, D. F.; Alaghamandan, H. A.; Bartlett, M. L.; Robins, R. K.: Antiviral Chem. 1, 47 (1990); C.A. 113, 184255 t (1990)
4. Kinni, G. D.; Anderson, J. D.; Sanghvi, Y. S.; Lewis, A. F.; Smee, D. F.; Revankar, G. R.; Robins, R. K.; Cottam, H. B.: J. Med. Chem. 34, 3006 (1991)
5. Smee, D. F.; Alaghamandan, H. A.; Gilbert, J., Burger, R. A.; Jin, A.; Sharma, B. S.; Ramasamy, K.; Revankar, G. R.; Cottam, H. B.; et al.: Antimicrob. Agents Chemother. 35, 152 (1991); C.A. 114, 94699 g (1991)
6. Smee, D. F.; Alaghamandan, H. A.; Gilbert, J., Burger, R. A.; Jin, A.; Sharma, B. S.; Ramasamy, K.; Revankar, G. R.; Cottam, H. B.; et al.: Antimicrob. Agents Chemother. 35, 152 (1991); C.A. 114, 94699 g (1991)
7. Ghose, A. K.; Crippen, G. M.; Revankar, G. R.; Mckernan, P. A.; Smee, D. F.; Robins, R. K.: J. Med. Chem. 32, 746 (1989)
8. Robins, R. K.; Cottam, H. B.: PCT Int. Appl. W.O. 89 05, 649; C.A. 112, 56584s (1990)
9. Devani, M. B.; Schishoo, C. J.; Pathak, U. S.; Parikh, S. H.; Radhakrishman, A. V.; Padhya, A. C.: Arzneim.-Forsch. 27, 1652 (1977)
10. Grohe, K.; (Bayer AG): Ger. Offen 2, 223, 421 (1973); C.A. 80, 37148g (1974)
11. Grohe, K.; (Bayer AG): Ger. Offen 2, 223, 421 (1973); C.A. 80, 37148g (1974)
12. Abdel-Rahman, R. M.; El-Gendy, Z.; Mahmoud, M. B.: J. Indian Chem. Soc. 67, 61 (1990)
13. Cowper, A. J.; Astik, R. R.; Thaker, K. A.: J. Inst. Chem. 53, 224 (1981); C.A. 96, 122679 f (1982)
14. Cowper, A. J.; Astik, R. R.; Thaker, K. A.: J. Inst. Chem. 53, 224 (1981); C.A. 96, 122679 f (1982)
15. Lakhan, R.: Agric. Biol. Chem. 46, 557 (1982); C.A. 96, 157185 μ (1982)
16. Lakhan, R.: Agric. Biol. Chem. 46, 557 (1982); C.A. 96, 157185 μ (1982)
17. Garnaik, B. K.; Behera, R. K.: Indian J. Chem. Sect. B, 27B, 1157 (1988)
18. Habib, N. S.; El-Hawash, S. A.: Farmaco Ed. Sci. 44, 1225 (1989)
19. Singh, H.; Yadav, L. D. S.; Shukla, K. N.; Dwivedi, R.: Indian J. Pharm. Sci. 53, 1 (1991)
20. Reiner, R.: Antibiotics, p. 107, Georg Thieme Verlag, Stuttgart - New York 1982
21. Reynolds, J. E. F.: Martindale. The Extra Pharmacopoeia 29th ed. part 1, p. 147, The Pharmaceutical Press London 1989
22. Gupta, P. K.; Daunert, S.; Nassiri, M. R.; Worthing, L. L.; Drach, J. C.; Townsend, L. B.: J. Med. Chem. 32, 402 (1989)
23. Badawey, E. A. M.; Rida, S. M.; Hazzaa, A. A.; Fahmy, H. T. Y.; Gohar, Y. M.: Eur. J. Med. Chem. 28, 91 (1993)
24. Badawey, E. A. M.; Rida, S. M.; Hazzaa, A. A.; Fahmy, H. T. Y.; Gohar, Y. M.: Eur. J. Med. Chem. 28, 97 (1993)
25. Gewald, K.: J. Prakt. Chem. 32, 26 (1966)
26. Cänback, T.; Erne, K.: Svensk, Farm. Tidskr 59, 89 (1955); C.A. 50, 800 g (1956)
27. Cänback, T.; Erne, K.: Svensk, Farm. Tidskr 59, 89 (1955); C.A. 50, 800 g (1956)
28. Gewald, K.; Hain, U.; Hartung, P.: Monatsh. Chem. 112, 1393 (1981)
29. Jain, S. R.; Kar, A.: Planta. Med. 20, 118 (1971)
30. Weislow, O. W.; Kiser, R.; Fine, D.; Badr, J.; Shoemaker, R. H.; Boyed, M. R.: J. Natl. Cancer. Inst. 81, 577 (1989)
31. Boyed, M. R.: Principles and Practice of Oncology Updates 3, 1 (1989)