Localization and activity of recombinant human CuZn superoxide dismutase after intratracheal administration

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 271, Issue 2 15-2, 1996, Pages

  Sahgal, Namita ^b   Davis, Jonathan M ^a   Robbins, Carolyn ^b   Horowitz, Stuart ^b   Langenback, Edward G ^b   Perry, Robert H ^b   Colflesh, David ^b   Tierney, Joan ^b   Simon, Sanford R ^b  

^a WINTHROP UNIVERSITY HOSPITAL   (United States)

^b NONE

Author keywords

antioxidants; fluorescence

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; DOSE TIME EFFECT RELATION; DRUG ACTIVITY; DRUG DISTRIBUTION; DRUG METABOLISM; FLUORESCENCE; HISTOPATHOLOGY; INTRATRACHEAL DRUG ADMINISTRATION; LUNG INJURY; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; SWINE;

EID: 0029820384     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.1996.271.2.l230     Document Type: Article

References (28)

1. Baker, R. R., L. Czopf, T. Jilling, B. A. Freeman, K. L. Kirk, and S. Matalon. Quantitation of alveolar distribution of liposome-entrapped antioxidant enzymes. Am. J. Physiol. 263 (Lung Cell Mol. Physiol. 7): L585-L594, 1992.
2. Crapo, J. D., D. M. DeLong, K. Sjostrom, G. R. Hasler, and R. T. Drew. The failure of aerosolized superoxide dismutase to modify pulmonary oxygen toxicity. Am. Rev. Respir. Dis. 115: 1027-1033, 1977.
3. Crapo, J. D., J. M. McCord, and I. Fridovich. Preparation and assay of superoxide dismutase. Meth. Enzymol. 53: 382-393, 1978.
4. Crapo, J. D., and D. F. Tierney. Superoxide dismutase and pulmonary oxygen toxicity. Am. J. Physiol. 226: 1401-1407, 1974
5. Davis, J. M., E. G. Langenback, C. G. Robbins, N. Sahgal, R. J. Perry, and S. S. Simon. Improved pulmonary distribution of recombinant human superoxide dismutase (rhSOD) using a newly developed ultrasonic nebulizer (Abstract). Am. J. Respir. Crit. Care Med. 149: A547, 1994.
6. Davis, J. M., W. N. Rosenfeld, R. J. Sanders, and A. Gonenne. Prophylactic effects of recombinant human superoxide dismutase in neonatal lung injury. J. Appl. Physiol. 74: 2234-2241, 1993.
7. Fantone, J. C., D. E. Feltner, J. K. Brieland, and P. A. Ward. Phagocytic cell-derived inflammatory mediators and lung disease. Chest 91: 428-435, 1987.
8. Fox, R. B., J. R. Hoidal, D. M. Brown, and J. E. Repine. Pulmonary inflammation due to oxygen toxicity: involvement of chemotactic factors and polymorphonuclear leukocytes. Am. Rev. Respir. Dis. 123: 521-523, 1981.
9. Frank, L. Developmental aspects of experimental pulmonary oxygen toxicity. Free Radical Biol. Med. 11: 463-494, 1991.
10. Freeman, B. A., and J. D. Crapo. Biology of disease: free radicals and tissue injury. Lab. Invest. 47: 412-426, 1982.
11. Freeman, B. A., and J. D. Crapo. Hyperoxia increases oxygen radical production in rat lungs and lung mitochondria. J. Biol. Chem. 256: 10986-10992, 1981.
12. Freeman, B. A., J. F. Turrens, Z. Mirza, J. D. Crapo, and S. L. Young. Modulation of oxidant lung injury by using liposome-entrapped superoxide dismutase and catalase. Federation Proc. 44: 2591-2595, 1985.
13. ++ superoxide dismutase. Chest 104: 811-815, 1993.
14. Jacobson, J. M., J. R. Michael, M. H. Jafri, Jr., and G. H. Gurtner. Antioxidants and antioxidant enzymes protect against pulmonary oxygen toxicity in the rabbit. J. Appl. Physiol. 68: 1252-1259, 1990.
15. Khanna, P. L., and E. F. Ullman. 4′,5′-Dimethoxy-6-carboxyfluorescein: a novel dipole-dipole coupled fluorescence energy transfer acceptor useful for fluorescence immunoassays. Anal. Biochem. 108: 156-161, 1980.
16. Mayo, L. A., and J. T. Curnutte. Kinetic microplate assay for superoxide production by neutrophils and other phagocytic cells. Meth. Enzymol. 186: 567-575, 1990.
17. McDonald, R. J., E. M. Berger, C. W. White, J. G. White, B.A. Freeman, and J. E. Repine. Effect of superoxide dismutase encapsulated in liposomes or conjugated with polyethylene glycol on neutrophil bactericidal activity in vitro and bacterial clearance in vivo. Am. Rev. Respir. Dis. 131: 633-637, 1985.
18. Merritt, T. A., C. G. Cochrane, K. Holcomb, B. Bohl, M. Hallman, D. Strayer, D. K. Edwards III, and L. Gluck. Elastase and alpha 1-proteinase inhibitor activity in tracheal aspirates during respiratory distress syndrome. Role of inflammation in the pathogenesis of bronchopulmonary dysplasia. J. Clin. Invest. 72: 656-666, 1983.
19. Padmanabhan, R. V., R. Gudapaty, I. E. Liener, B. A. Schwartz, and J. R. Hoidal. Protection against pulmonary oxygen toxicity in rats by the intratracheal administration of liposome-encapsulated superoxide dismutase or catalase. Am. Rev. Respir. Dis. 132: 164-167, 1985.
20. Rosenfeld, W. N., J. M. Davis, L. Parton, S. E. Richter, A. Price, E. Flaster, and N. Kassem. Safety and pharmacokinetics of recombinant human superoxide dismutase administered intratracheally to premature neonates with respiratory distress syndrome. Pediatrics 97: 811-817, 1996.
21. Rosenfeld, W. N., H. Evans, L. Concepcion, R. Jhaveri, H. Schaeffer, and A. Friedman. Prevention of bronchopulmonary dysplasia by administration of bovine superoxide dismutase in preterm infants with respiratory distress syndrome. J. Pediatr. 105: 781-784, 1984.
22. Smith, P. K., R. L. Krohn, G. T. Hermanson, A. K. Mallia, F. H. Gartner, M. D. Provenzano, E. K. Fujimoto, N. M. Goeke, B. J. Olson, and D. C. Klenk. Measurement of protein using bicinchoninic acid. Anal. Biochem. 150: 76-85, 1985.
23. Stenmark, K. R., M. Eyzaguirre, J. Y. Westcott, P. M. Henson, and R. C. Murphy. Potential role of eicosanoids and PAF in the pathophysiology of bronchopulmonary dysplasia. Am. Rev. Respir. Dis. 136: 770-772, 1987.
24. Tang, G., J. E. White, R. J. Gordon, P. D. Lumb, and M. F. Tsan. Polyethylene glycol-conjugated superoxide dismutase protects rats against oxygen toxicity. J. Appl. Physiol. 74: 1425-1431, 1993.
25. 2 tosicity in the newborn rat. J. Appl. Physiol. 63: 347-352, 1987.
26. Turrens, J. F., J. D. Crapo, and B. A. Freeman. Protection against oxygen toxicity by intravenous injection of liposome-entrapped catalase and superoxide dismutase. J. Clin. Invest. 73: 87-95, 1984.
27. Turrens, J. F., B. A. Freeman, J. G. Levitt, and J. D. Crapo. The effect of hyperoxia on superoxide production by lung submitochondrial particles. Arch. Biochem. Biophys. 217: 401-410, 1982.
28. Yam, J., and R. J. Roberts. Oxygen induced lung injury in the newborn piglet. Early Hum. Dev. 4: 411-424, 1980.