메뉴 건너뛰기




Volumn 40, Issue 10, 1996, Pages 2318-2320

Continuous infusion of DL-α-difluoromethylornithine and improved efficacy against a rat model of Pneumocystis carinii pneumonia

Author keywords

[No Author keywords available]

Indexed keywords

DRINKING WATER; EFLORNITHINE; SULFAMETHOXAZOLE; TRIMETHOPRIM;

EID: 0029820317     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.40.10.2318     Document Type: Article
Times cited : (13)

References (25)
  • 1
  • 3
    • 0025108249 scopus 로고
    • Deferoxamine and eflornithine (DL-α-difluoromethylornithine) in a rat model of Pneumocystis carinii pneumonia
    • Clarkson, A. B., Jr., M. Sarić, and R. W. Grady. 1990. Deferoxamine and eflornithine (DL-α-difluoromethylornithine) in a rat model of Pneumocystis carinii pneumonia. Antimicrob. Agents Chemother. 34:1833-1835.
    • (1990) Antimicrob. Agents Chemother. , vol.34 , pp. 1833-1835
    • Clarkson Jr., A.B.1    Sarić, M.2    Grady, R.W.3
  • 4
    • 0023722304 scopus 로고
    • Efficacy of DL-α-difluorumethylornithine in a rat model of Pneumocystis carinii pneumonia
    • Clarkson, A. B., Jr., D. E. Williams, and C. Rosenberg. 1988. Efficacy of DL-α-difluorumethylornithine in a rat model of Pneumocystis carinii pneumonia. Antimicrob. Agents Chemother. 32:1158-1163.
    • (1988) Antimicrob. Agents Chemother. , vol.32 , pp. 1158-1163
    • Clarkson Jr., A.B.1    Williams, D.E.2    Rosenberg, C.3
  • 5
    • 0022409732 scopus 로고
    • Method of testing the susceptibility of Pneumocyslis carinii to antimicrobial agents in vitro
    • Cushion, M. T., D. Stanforth, M. J. Linke, and P. D. Walzer. 1985. Method of testing the susceptibility of Pneumocyslis carinii to antimicrobial agents in vitro. Antimicrob. Agents Chemother. 28:796-801.
    • (1985) Antimicrob. Agents Chemother. , vol.28 , pp. 796-801
    • Cushion, M.T.1    Stanforth, D.2    Linke, M.J.3    Walzer, P.D.4
  • 7
    • 0021717176 scopus 로고
    • Pneumocyslis carinii pneumonia treated with a-difluoromethylornithine. A prospective study among patients with the acquired immunodeficiency syndrome
    • Golden, J. A., A. Sjoerdsma, and D. V. Santi. 1984. Pneumocyslis carinii pneumonia treated with a-difluoromethylornithine. A prospective study among patients with the acquired immunodeficiency syndrome. West. J. Med. 141:613-623.
    • (1984) West. J. Med. , vol.141 , pp. 613-623
    • Golden, J.A.1    Sjoerdsma, A.2    Santi, D.V.3
  • 8
    • 0019830966 scopus 로고
    • Assay of α-difluoromethylornithine in body fluids and tissues by automatic amino-acid analysis
    • Grove, J., J. R. Fozard, and P. S. Mamont. 1981. Assay of α-difluoromethylornithine in body fluids and tissues by automatic amino-acid analysis. J. Chromatogr. 223:409-416.
    • (1981) J. Chromatogr. , vol.223 , pp. 409-416
    • Grove, J.1    Fozard, J.R.2    Mamont, P.S.3
  • 9
    • 0019838777 scopus 로고
    • Kinetics of α-difluoromethylornithine: An irreversible inhibitor of ornithine decarboxylase
    • Haegele, K. D., R. G. Alken, J. Grove, P. J. Schechter, and J. Koch-Weser. 1981. Kinetics of α-difluoromethylornithine: an irreversible inhibitor of ornithine decarboxylase. Clin. Pharmacol. Ther. 30:210-217.
    • (1981) Clin. Pharmacol. Ther. , vol.30 , pp. 210-217
    • Haegele, K.D.1    Alken, R.G.2    Grove, J.3    Schechter, P.J.4    Koch-Weser, J.5
  • 10
    • 0021129248 scopus 로고
    • Efficacy of diaminodiphenylsulfone and other drugs in murine Pneumocystis carinii pneumonitis
    • Hughes, W. T., and B. L. Smith. 1984. Efficacy of diaminodiphenylsulfone and other drugs in murine Pneumocystis carinii pneumonitis. Antimicrob. Agents Chemother. 26:436-440.
    • (1984) Antimicrob. Agents Chemother. , vol.26 , pp. 436-440
    • Hughes, W.T.1    Smith, B.L.2
  • 11
    • 0025873205 scopus 로고
    • Polyamine metabolism in Pneumocystis carinii
    • Lipschik, G. Y., H. Masur, and J. A. Kovacs. 1991. Polyamine metabolism in Pneumocystis carinii. J. Infect. Dis. 163:1121-1127.
    • (1991) J. Infect. Dis. , vol.163 , pp. 1121-1127
    • Lipschik, G.Y.1    Masur, H.2    Kovacs, J.A.3
  • 13
    • 0029868424 scopus 로고    scopus 로고
    • Polyamine content of Pneumocystis carinii and response to the ornithine decarboxylase inhibitor DL-α-difluoromethylornithine
    • Merali, S., and A. B. Clarkson, Jr. 1996. Polyamine content of Pneumocystis carinii and response to the ornithine decarboxylase inhibitor DL-α-difluoromethylornithine. Antimicrob. Agents Chemother. 40:973-978.
    • (1996) Antimicrob. Agents Chemother. , vol.40 , pp. 973-978
    • Merali, S.1    Clarkson Jr., A.B.2
  • 14
    • 10144262187 scopus 로고
    • Merrell Dow Pharmaceutical, Cincinnati, Ohio
    • Merrell Dow Pharmaceuticals. 1981. Investigational brochure for DFMO. Merrell Dow Pharmaceutical, Cincinnati, Ohio.
    • (1981) Investigational Brochure for DFMO
  • 15
    • 0027234946 scopus 로고
    • Eflornithine concentrations in serum and cerebrospinal fluid of 63 patients treated for Trypanosoma brucei gambiense sleeping sickness
    • Milord, F., L. Loko, L. Éthier, B. Mpia, and J. Pépin. 1993. Eflornithine concentrations in serum and cerebrospinal fluid of 63 patients treated for Trypanosoma brucei gambiense sleeping sickness. Trans. R. Soc. Trop. Med. Hyg. 87:473-477.
    • (1993) Trans. R. Soc. Trop. Med. Hyg. , vol.87 , pp. 473-477
    • Milord, F.1    Loko, L.2    Éthier, L.3    Mpia, B.4    Pépin, J.5
  • 17
    • 0026574444 scopus 로고
    • Eflornithine treatment of refractory Pneumocyslis carinii pneumonia in patients with acquired immunodeficiency syndrome
    • Paulson, Y. J., T. M. Gilman, P. N. R. Heseltine, O. P. Sharma, and C. T. Boylen. 1992. Eflornithine treatment of refractory Pneumocyslis carinii pneumonia in patients with acquired immunodeficiency syndrome. Chest 101:66-74.
    • (1992) Chest , vol.101 , pp. 66-74
    • Paulson, Y.J.1    Gilman, T.M.2    Heseltine, P.N.R.3    Sharma, O.P.4    Boylen, C.T.5
  • 18
    • 0024110205 scopus 로고
    • Lack of detectable activity of ornithine decarboxylase in Pneumocystis carinii
    • Pesanti, E. L., M. S. Bartlett, and J. W. Smith. 1988. Lack of detectable activity of ornithine decarboxylase in Pneumocystis carinii. J. Infect. Dis. 158:1137-1138.
    • (1988) J. Infect. Dis. , vol.158 , pp. 1137-1138
    • Pesanti, E.L.1    Bartlett, M.S.2    Smith, J.W.3
  • 19
    • 0024507336 scopus 로고
    • Eflornithine for the treatment of Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome: A preliminary review
    • Sahai, J., and A. J. Berry. 1989. Eflornithine for the treatment of Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome: a preliminary review. Pharmacotherapy 9:29-33.
    • (1989) Pharmacotherapy , vol.9 , pp. 29-33
    • Sahai, J.1    Berry, A.J.2
  • 20
    • 0027971603 scopus 로고
    • Ornithine decarboxylase in Pneumocystis carinii and implications for therapy
    • Sarić, M., and A. B. Clarkson, Jr. 1994. Ornithine decarboxylase in Pneumocystis carinii and implications for therapy. Antimicrob. Agents Chemother. 38:2545-2552.
    • (1994) Antimicrob. Agents Chemother. , vol.38 , pp. 2545-2552
    • Sarić, M.1    Clarkson Jr., A.B.2
  • 21
    • 0026558453 scopus 로고
    • New developments in the treatment of Pneumocystis carinii pneumonia
    • Sattler, F. R., and J. Feinberg. 1992. New developments in the treatment of Pneumocystis carinii pneumonia. Chest 101:451-457.
    • (1992) Chest , vol.101 , pp. 451-457
    • Sattler, F.R.1    Feinberg, J.2
  • 22
    • 0025197133 scopus 로고
    • Pneumocystis carinii pneumonia treated with eflornithine in AIDS patients resistant to conventional therapy
    • Smith, D., S. Davies, M. Nelson, M. Youle, J. Gleeson, and B. Gazzard. 1990. Pneumocystis carinii pneumonia treated with eflornithine in AIDS patients resistant to conventional therapy. AIDS 4:1019-1021.
    • (1990) AIDS , vol.4 , pp. 1019-1021
    • Smith, D.1    Davies, S.2    Nelson, M.3    Youle, M.4    Gleeson, J.5    Gazzard, B.6
  • 23
    • 0027082509 scopus 로고
    • Eflornithine versus cotrimoxizole in the treatment of Pneumocystis carinii pneumonia in AIDS patients
    • Smith, D. E., S. Davies, J. Smithson, I. Harding, and B. G. Gazzard. 1992. Eflornithine versus cotrimoxizole in the treatment of Pneumocystis carinii pneumonia in AIDS patients. AIDS 6:1489-1493.
    • (1992) AIDS , vol.6 , pp. 1489-1493
    • Smith, D.E.1    Davies, S.2    Smithson, J.3    Harding, I.4    Gazzard, B.G.5
  • 24
    • 0027278550 scopus 로고
    • Pharmacokinetic optimisation in the treatment of Pneunocystis carinii pneumonia
    • Vohringer, H.-F., and K. Arasteh. 1993. Pharmacokinetic optimisation in the treatment of Pneunocystis carinii pneumonia. Clin. Pharmacokinet. 24:388-412.
    • (1993) Clin. Pharmacokinet. , vol.24 , pp. 388-412
    • Vohringer, H.-F.1    Arasteh, K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.