In situ detection of hepatitis C virus - A critical appraisal

Journal of Hepatology, Supplement

Volumn 24, Issue 2, 1996, Pages 43-51

  Lau, Johnson Y N ^a   Krawczynski, Krzysztof ^b,e   Negro, Francesco ^c   Gonzâlez Peralta, Regino P ^d  

^a Section of Hcpatobiliary Diseases   (Switzerland)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^c CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^d UNIVERSITY OF GENEVA   (Switzerland)

^e Section of Hepatobiliary Diseases   (United States)

Author keywords

HCV; Immunohistochemistry; In situ detection; In situ hybridization; In situ RT PCR; Localization

Indexed keywords

GENE PRODUCT; VIRUS PROTEIN; VIRUS RNA;

CONFERENCE PAPER; GENE AMPLIFICATION; HEPATITIS C VIRUS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS; RNA VIRUS; TISSUE DISTRIBUTION; VIRUS DETECTION; VIRUS GENOME; VIRUS REPLICATION;

HEPACIVIRUS; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LIVER; POLYMERASE CHAIN REACTION;

EID: 0029819665     PISSN: 01695185     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (35)

1. Feinstone SM, Kapikian AZ, Purcell RH, Alter HJ, Holland PV. Transfusion-associated hepatitis not due to viral hepatitis type A or B. N Engl J Med 1975; 292: 767-70.
2. Dienstag JL, Feinstone SM, Purcell RH, Wong DC, Alter HJ, Holland PV. Non-A, non-B post-transfusion hepatitis. Lancet 1977; 1: 560-2.
3. Choo QL, Weiner AJ, Overby LR, Kuo G, Houghton M, Bradley DW. Hepatitis C virus: The major causative agent of viral non-A, non-B hepatitis. Br Med Bull 1990; 46: 42341.
4. Choo QL, Kuo G, Weiner AJ, Overby LR, Bradley DW, Houghton M. Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome. Science 1989; 244: 359-61.
5. Choo QL, Richman KH, Han JH, Berger K, Lee C, Dong C, Gallegos C, Coit D, Medine-Selby R, Barr J, et al. Genetic organization and diversity of the hepatitis C virus. Proc Natl Acad Sei USA 1991; 88: 2451-5.
6. Takamizawa A, Mori C, Fuke I, Manabe S, Murakami S, Fujita J, Onishi E, Andoh T, Yoshida I, Okayama H. Structure and organization of the hepatitis C virus genome isolated from human carriers. J Virol 1991; 65: 1105-13.
7. Lau JYN, Davis GL, Kniffen J, Qian KP, Urdea MS, Chan CS, Mizokami M, Nuewald PD, Wilber JC. Significance of serum hepatitis C virus RNA levels in chronic hepatitis C. Lancet 1993; 341: 1501.
8. Lau JYN. Hepatitis C virus: from epidemiology and molecular virology to immunobiology. Hepatology 1994; 20: 760-2.
9. Negro F. Pacchioni D, Shimizu Y, Miller RH, Bussolati G, Purcell RH, Bonino F. Detection of intrahepatic replication of hepatitis C virus RNA by in situ hybridization and comparison with histopathology. Proc Natl Acad Sei USA 1992; 89: 2247-51.
10. Noun-Aria KT, Sallie R, Sangar D, Alexander GJM, Smith H, Byrne J. Portmann B. Eddleston ALWF, Williams R. Detection of genomic and intermediate replicative strands of hepatitis C virus in liver tissue by in situ hybridization. J Clin Invest 1993;91:2226-34.
11. Yamada S, Koji T, Nozawa M, Kiyosawa K, Nakane PK. Detection of hepatitis C virus (HCV) RNA in paraffin embedded tissue sections of human liver of non-A, non-B hepatitis patients by in situ hybridization. Dig Dis Sei 1993; 38: 882-7.
12. Tanaka Y, Enomoto N, Kojima S, Tang L, Goto M, Marumo F, Sato C. Detection of hepatitis C virus RNA in the liver by in situ hybridization. Liver 1993; 13: 203-8.
13. Blight K, Trowbridge R, Rowland R, Gowans E. Detection of hepatitis C virus RNA by in situ hybridization. Liver 1992; 12: 286-9.
14. Lamas E. Baccarini P, Housset C, Kremsdorf D, Brechet C. Detection of hepatitic C virus (HCV) RNA sequences in liver tissue by in situ hybridization. J Hepatol 1992; 16: 21923.
15. Haruna Y, Hayashi N, Hiramatsu N, Takehara T, Hagiwara H, Sasaki Y, Kasahara A, Fusamoto H, Kamada T. Detection of hepatitis C virus RNA in liver tissues by an in situ hybridization technique. J Hepatol 1993; 18: 96-100.
16. Tox U, Kolbe E, Tien D, Kraussüch HG, Hoffmann WJ, Muller HM. Goeser T, Nawroth PP, Kommerell B, Theilmann L. Detection of hepatitis C virus RNA in liver paraffin sections by in situ hybridization: distribution and identification of infected cells. Hepatology 1993; 18: 82A.
17. Lau JYN, Davis GL. Detection of hepatitis C virus RNA genome in liver tissue by non-isotopic in situ hybridization. J Med Virol 1994; 42: 268-71.
18. Marrone A, Kleiner D, Mahanev K, Conjeeveran H, Tadeschi V, Hoofnagle JH, Sallie R. The significance of hepatic HCV RNA: Analysis by semiquantitative in situ hybridization. Hepatology 1994; 20: 236A (Abstr).
19. Komminoth P, Adams V, Roth J, Saremaslani P, Flury R, Schmid M, Heitz PU. Evaluation of methods for hepatitis C virus (HCV) detection in archival liver biopsies: comparison of immunohistochemistry, ISH, RT-PCR and in situ RTPCR. Pathol Res Pract 1994; 190: 1017-25.
20. Nuovo GJ, Lidonnici K, MacConnell P, Lane B. Intracellular localization of polymerase chain reaction (PCR)-amplified hepatitis C cDNA. Am J Surg Pathol 1993; 17: 683-90.
21. Lau GKK, Fang JWS, Wu PC, Davis GL, Lau JYN. Detection of hepatitis C virus genome in formalin-fixed paraffinembedded liver tissue by in situ reverse transcription polymerase chain reaction. J Med Virol 1994; 44: 406-9.
22. Lau GKK, Davis GL, Wu SPC, Gish RG, Baiart LA, Lau JYN. Hepatic expression of hepatitis C virus RNA in chronic hepatitis C: a study by in-situ reverse transcription polymerase chain reaction. Hepatology 1996; in press.
23. Infantolino D, Bonino F, Zanetti, Lesniewski RR, Barbazza R, Chiaramonte M. Localization of hepatitis C antigen(s) by immunohistochemistry on fixed-embedded liver tissue. Ital J Gastroenterol 1990; 22: 198-9.
24. Krawczynski K, Beach MJ, Bradley DW, Kuo G, DiBisceglie AM, Houghton M, Reyes GR, Kim JP, Choo QL, Alter MJ. Hepatitis C virus antigen in hepatocytes: immuno'morphologic detection and identification. Gastroenterology 1992; 103: 622-9.
25. DiBisceglie AM, Krawczynski K, Brazzeal D, Hoofnagle JH. Hepatitis C viral antigen (HCV Ag) in the liver: effect of antiviral therapy. Gastroenterology 1993; 105: 858-62.
26. Hiramatsu N, Hayashi N, Haruna Y, Kasahara A, Fusamoto H, Mori C, Fuke I, Okayama H, Kamada T. Immunohistochemical detection of hepatitis C virus-infected hepatocytes in chronic liver disease with monoclonal antibodies to core, envelope and NS3 regions of the hepatitis C virus genome. Hepatology 1992; 16: 306-11.
27. Blight K, Rowland R, Hall PD, Immunohistochemical detection of the NS4 antigen of hepatitis C virus and its relation to histopathology. Am J Pathol 1993; 143: 1568-73.
28. Blight K, Lesniewski RR, LaBrooy JT, Gowans EJ. Detection and distribution of hepatitis C-specific antigens in naturally infected liver. Hepatology 1994; 20: 553-7.
29. Yap SH, Willems M, Van den Oord J, Habets W, Middledorp JM, Hellings JA, Nevens F, Moshage H, Desmet V, Fevery J. Detection of hepatitis C virus antigen by immunohistochemical staining: a histological marker of hepatitis C virus infection. J Hepatol 1994; 20: 275-81.
30. Tsutsumi M, Urashima S, Takada A, Date T, Tanaka Y. Detection of antigens related to hepatitis C virus RNA encoding the NS5 region in the livers of patients with chronic type C hepatitis. Hepatology 1994; 19: 265-72.
31. Sansonno D, Dammacco F. Hepatitis C virus clOO antigen in liver tissue from patients with acute and chronic infection. Hepatology 1993; 18: 240-5.
32. Gonzâlez-Peralta RP, Fang JWS, Davis GL, Gish RG, Tsukiyama-Kohara K, Kohara M, Mondelli MU, Lesniewski R, Phillips MI, Mizokami M, Lau JYN. Optimization for the detection of hepatitis C virus antigens in the liver. J Hepatol 1994; 20: 143-7.
33. Gonzâlez-Peralta RP, Fang JWS, Davis GL, Gish RG, Kohara M, Mondelli MU, Urdea MS, Mizokami M, Lau JYN. Significance of hepatic expression of hepatitis C viral antigens in chronic hepatitis C. Dig Dis Sei 1995; 40: 2595-601.
34. Gretch DR, Gown AM, Bacchi C, Frank I, Lesniewski R, Perkins J, Carithers Jr RL. Detection of hepatitis C virus NS4 antigen in hepatocytes during asymptomatic viremia. Hepatology 1994; 20: suppl 2, 235A (Abstr).
35. Rode J, Lee CS, Ayberk P, Desmond S, Locarnini S, Bowden S, Lee JY. Demonstration of HVC in fixed liver tissue with anti double-stranded RNA. Gastroenterology 1993; 104; part 2: A979 (Abstr).