Self-medication of a single headache episode with ketoprofen, ibuprofen or placebo, home-monitored with an electronic patient diary

British Journal of Clinical Pharmacology

Volumn 42, Issue 4, 1996, Pages 475-481

  Van Gerven, J M A ^a   Schoemaker, R C ^a   Jacobs, L D ^b   Reints, A ^a   Ouwersloot van Der Meij, M J ^a   Hoedemaker, H G J ^c   Cohen, A F ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b Rhone Poulenc Rorer GmbH   (Germany)

^c Rhone Poulenc Rorer Nederland B V   (Netherlands)

Author keywords

clinical trials; electronic diaries; headache; non steroid anti inflammatory drugs; self medication

Indexed keywords

IBUPROFEN; KETOPROFEN; PLACEBO;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; ELECTRONICS; GASTROINTESTINAL SYMPTOM; HEADACHE; HUMAN; MAJOR CLINICAL STUDY; PATIENT MONITORING; PRIORITY JOURNAL; PRURITUS; QUESTIONNAIRE; RANDOMIZED CONTROLLED TRIAL; REGISTRATION; RESTLESSNESS; SELF MEDICATION;

EID: 0029819308     PISSN: 03065251     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2125.1996.tb00011.x     Document Type: Article

References (20)

1. Veys EM. Twenty years experience with ketoprofen. Scand J Rheumatol 1991; 20 (suppl. 90): 3-44.
2. Cooper SA. Ketoprofen in oral surgery pain: a review. J Clin Pharmacol 1988; 28 (suppl. 12): S40-S46.
3. Cooper SA, Berrie R. Cohn P. Comparison of ketoprofen, ibuprofen, and placebo in a dental surgery pain model. Adv Ther 1988; 5: 43-53.
4. Mehlisch DR. Double-blind crossover comparison of ketoprofen, naproxen, and placebo in patients with primary dysmenorrhea. Clin Ther 1990; 12: 398-409.
5. Sunshine A, Zighelboim I, Laska E, Siegel C, Olson NZ, De Castro A. A double-blind, parallel comparison of ketoprofen, aspirin, and placebo in patients with postparlum pain. J Clin Pharmacol 1986; 24: 706-711.
6. Sunshine A, Olson NZ. Analgesic efficacy of ketoprofen in postpartum, general surgery, and chronic cancer pain. J Clin Pharmacol 1988; 28 (suppl. 12): S47-S54
7. Arnold JD. Ketoprofen, ibuprofen, and placebo in the relief of postoperative pain. Adv Ther 1990; 7: 264-275.
8. Turek MD, Baird WM. Double-blind parallel comparison of ketoprofen, acetaminophen + codeine, and placebo in postoperative pain. J Clin Pharmacol 1988; 28 (suppl. 12): S23-S28.
9. Stambaugh J, Drew J. A double-blind parallel evaluation of the efficacy and safety of a single dose of ketoprofen in cancer pain. J Clin Pharmacol 1988; 28 (suppl. 12): S34-S39.
10. Headache Classification Committee of the International Headache Society (IHS). Classification and diagnostic criteria for headache disorders, cranial neuralgias and facial pain. Cephalagia 1988; 8 (suppl. 7): 1-96.
11. Caviness VS jr. O'Brien P. Headache. N Engl J Med 1980; 302: 446-450.
12. Von Graffenfield B, Hill RC, Nuesch E. Headache as a model for assessing mild analgesic drugs. J Clin Pharmacol 1980; 20: 298-302.
13. Miller DD, Talbot CA, Simpson W, Korey A. A comparison of naproxen sodium, acetaminophen and placebo in the treatment of muscle contraction headache. Headache 1987; 27: 392-396.
14. Diamond S. Ibuprofen versus aspirin and placebo in the treatment of muscle contraction headache. Headache 1983; 23: 206-210.
15. Schachtel BP, Thoden WR. Onset of action of ibuprofen in the treatment of muscle-contraction headache. Headache 1988; 28: 471-474.
16. Guidotti M, Zanasi S, Garagiola U. Pirprofen in the treatment of migraine and episodic headache attacks: a placebo-controlled crossover clinical trail. J Int Med Res 1989; 17: 48-54.
17. Anonymous. US ketoprofen switch approved. Scrip 1995; (2069): 21.
18. Schachtel BP, Thoden WR, Konerman JP, Brown A, Chaing DS. Headache pain model for assessing and comparing the efficacy of over-the-counter analgesic agents. Clin Pharmacol Ther 1991; 50: 322-329.
19. Lundström S. Electronic patient diaries. Appl Clin Trials 1993; 2: 35-38.
20. Schachtel BP, Cleves GS, Konerman JP, Brown AT, Markham AO. A placebo-controlled model to assay the onset of action of nonprescription-strength analgesic drugs. Clin Pharmacol Ther 1994; 55: 464-470.