Herpes simplex virus type 1 alters transcript levels of tumor necrosis factor-α and interleukin-6 in retinal glial cells

Investigative Ophthalmology and Visual Science

Volumn 37, Issue 11, 1996, Pages 2302-2312

  Drescher, Kristen M ^a   Whittum Hudson, Judith A ^a  

^a NONE

Author keywords

cytokines; glia; herpes simplex virus type 1 (HSV 1); interleukin 6; mouse; Muller cells; retina; tumor necrosis factor

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; FEMALE; GLIA; GLIA CELL; HERPES SIMPLEX VIRUS 1; IMMUNOMODULATION; INFLAMMATION; MOUSE; MUELLER CELL; NONHUMAN; PRIORITY JOURNAL; RETINA; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION REGULATION; VIRUS INFECTION;

ANIMALS; CELLS, CULTURED; CYTOKINES; EYE INFECTIONS, VIRAL; FEMALE; HERPES SIMPLEX; HERPESVIRUS 1, HUMAN; IN SITU HYBRIDIZATION; INTERFERON-GAMMA, RECOMBINANT; INTERLEUKIN-6; MALE; MICE; MICE, INBRED BALB C; NEUROGLIA; POLYMERASE CHAIN REACTION; RETINA; RETINITIS; RNA, MESSENGER; TRANSCRIPTION, GENETIC; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 0029819301     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (65)

1. Whittum-Hudson JA. HSV-induced stimulation of retinal Müller cells in vivo. ARVO Abstracts. Invest Ophthalmol Vis Sci. 1992;33(suppl):786.
2. Bignami A, Dahl D. The radial glia of Müller in the rat retina and their response to injury: An immunofluorescence study with antibodies to the GFAP. Exp Eye Res. 1979;28:63-69.
3. Sarthy PV, Fu M. Transcriptional activation of an intermediate filament protein gene in mice with retinal dystrophy. DNA. 1989;8:437-446.
4. Ekstrom P, Sanyal S, Narfstrom K, et al. Accumulation of glial fibrillary acidic protein in Müller radial glia during retinal degeneration. Invest Ophthalmol Vis Sci. 1988;29:1363-1371.
5. Erickson PA, Fisher SK, Guerin CJ, et al. Glial acidic fibrillary protein increases in Müller cells after retinal detachment. Exp Eye Res. 1987;44:37-46.
6. Eng LF. Glial fibrillary acidic protein (GFAP): The major protein of glial intermediate filaments in differentiated astrocytes. J Neuroimmunol. 1985;8:203-214.
7. Lieberman AP, Pitha PM, Shin HS, Shin ML. Production of TNF and other cytokines by astrocytes stimulated with lipopolysaccharide or a neurotropic virus. Proc Natl Acad Sci USA. 1989;86:6348-6352.
8. Chung IY, Benveniste EN. Tumor necrosis factor-α production by astrocytes: Induction by lipopolysaccharide, IFN-γ, and IL-1β. J Immunol. 1990;144:2999-3007.
9. Roberge FG, Caspi RR, Chan C, et al. Long-term culture of Müller cells from adult rats in the presence of activated lymphocytes/monocytes products. Exp Eye Res. 1985;4:975-982.
10. Sher A, Coffman RL, Hieny S, et al. Interleukin-5 is required for the blood and tissue eosinophilia but not granuloma formation induced by infection with Schistosoma mansoni. Proc Natl Acad Sci USA. 1990; 87:61-65.
11. Yamamura M, Uyemura K, Deans RJ, et al. Defining protective responses to pathogens: Cytokine profiles in leprosy lesions. Science. 1991;254:277-279.
12. Haanen JB, deWaal Malefijt R, Res PC, et al. Selection of a human T helper type 1-like T cell subset by mycobacteria. J Exp Med. 1991;174:583-592.
13. Kemp M, Hey AS, Kurtzhals JA, et al. Dichotomy of the human T cell response to Leishmania antigens: I: Th1-like response to Leishmania major promastigote antigens in individuals recovered from cutaneous leishmaniasis. Clin Exp Immunol. 1994;96:410-415.
14. Beutler B, Cerami A. The biology of cachectin/TNF - α primary mediator of the host response. Ann Rev Immunol. 1989;7:625-655.
15. Van Snick J. Interleukin-6: An overview. Ann Rev Immunol. 1990;8:253-278.
16. Kishimoto T, Taga T, Akira S. Cytokine signal transduction. Cell. 1994;76:253-262.
17. Genis P, Jett M, Bernton EW, et al. Cytokines and arachidonic metabolites produced during human immunodeficiency virus (HFV)-infected macrophage-astroglia interactions: Implications for the neuropathogenesis of HIV disease. J Exp Med. 1992;176:1703-1718.
18. Vitkovic L, Wood GP, Major EO, Fauci AS. Human astrocytes stimulate HFV-1 expression in a chronically infected promonocyte clone via interleukin-6. AIDS Res Hum Retroviruses. 1991;7:723-727.
19. LaVail MM, Unoki K, Yasumura D, et al. Multiple growth factors, cytokines, and neurotrophins rescue photoreceptors from the damaging effects of constant light. Proc Natl Acad Sci USA. 1992;89:11249-11253.
20. Streilein JW, Bradley D. Analysis of immunosuppressive properties of iris and ciliary body cells and their secretory products. Invest Ophthalmol Vis Sci. 1991; 32:2700-2710.
21. DeVos AF, VanHaren MAC, Verhagen C, et al. Tumour necrosis factor-induced uveitis in the Lewis rat is associated with intraocular interleukin-6 production. Exp Eye Res. 1995;60:199-207.
22. Streilein JW, Cousins SW. Aqueous humor factors and their effect on the immune response in the anterior chamber. Curr Eye Res. 1990;9:175-182.
23. Roberge FG, Caspi RR, Nussenblatt RR. Glial retinal Müller cells produce IL-1 activity and have a dual effect on autoimmune T helper lymphocytes: Antigen presentation manifested after removal of suppressive activity. J Immunol. 1988;140:2193-2196.
24. Pasquale LR, Dorman-Pease ME, Lutty GA, et al. Immunolocalization of TGFβ1, TGFβ2 and TGFβ3 in the anterior segment of the human eye. Invest Ophthalmol Vis Sci. 1993;34:23-30.
25. Kuppner MC, McKillop-Smith S, Forrester JV. TGF-β and IL-1β act in synergy to enhance IL-6 and IL-8 mRNA levels and IL-6 production by human retinal pigment epithelial cells. Immunology. 1995;84:265-271.
26. Planck SR, Dang TT, Graves D, et al. Retinal pigment epithelial cells secrete interleukin-6 in response to interleukin-1. Invest Ophthalmol Vis Sci. 1992;33:78-82.
27. Einer VM, Strieter RM, Einer SG, et al. Neutrophil chemotactic factor (IL-8) gene expression by cytokine-treated retinal pigment epithelial cells. Am J Pathol. 1990;136:745-750.
28. Drescher KM, Whittum-Hudson JA. Modulation of immune-associated surface markers and cytokine production by murine retinal glial cells. J Neuroimmunol. 1996;64:71-81.
29. Merges MJ, Whittum-Hudson JA. In vitro susceptibility of murine retinal cells to herpes simplex virus type 1. Invest Ophthalmol Vis Sci. 1990;31:1223-1230.
30. Politi L, Lehar M, Adler R. Development of neonatal mouse retinal neurons and photoreceptors in low density cell culture. Invest Ophthalmol Vis Sci. 1988; 29:534-543.
31. Whittum JA, McCulley JP, Niederkorn JY, Streilein JW. Ocular disease induced in mice by anterior chamber inoculation of herpes simplex virus. Invest Ophthalmol Vis Sci. 1984;25:1065-1073.
32. Murray L, Martens C. Abnormal T cells from lpr mice down-regulate transcription of interferon-γ and tumor necrosis factor-α in vitro. Cell Immunol. 1990; 126:367-376.
33. Montgomery RA, Dallman MJ. Analysis of cytokine gene expression during fetal thymic ontogeny using the polymerase chain reaction. J Immunol. 1991; 147:554-560.
34. Wynn TA, Eltoum I, Cheever AW, et al. Analysis of cytokine mRNA expression during primary granuloma formation induced by eggs of Schistosoma mansoni. J Immunol. 1993;151:1430-1440.
35. Ginsberg HS. Herpesviruses. In: Dulbecco R, Ginsberg HS, eds. Virology. Philadelphia: JB Lippincott; 1988: 161-178.
36. Whittum JA, Niederkorn JY, McCulley JP, Streilein JW. Intracameral inoculation of HSV type 1 induces anterior chamber associated immune deviation. Curr Eye Res. 1983;2:691-697.
37. Whittum-Hudson J, Merges MJ. Variations in herpes simplex-induced systemic immunity after intracameral injection of DNA polymerase mutants. ARVO Abstracts. Invest Ophthalmol Vis Sci. 1987;28:241.
38. Whittum-Hudson JA, Merges MJ, Field HJ. Immunogenicity versus pathogenicity after anterior chamber inoculation of an acyclovir-induced double mutant of HSV-1. Curr Eye Res. 1987;6:1459-1470.
39. Cousins SW, Gonzalez A, Atherton SS. Herpes simplex retinitis in the mouse: Clinicopathologic correlations. Invest Ophthalmol Vis Sci. 1989;30:1485-1494.
40. Atherton SS, Altman NH, Streilein JW. Two waves of virus following anterior chamber inoculation of HSV-1. Invest Ophthalmol Vis Sci. 1987;28:571-579.
41. Whittum-Hudson JA, Pepose JS. Immunologic modulation of virus-induced pathology in a murine model of acute herpetic retinal necrosis. Invest Ophthalmol Vis Sco. 1987;28:1541-1548.
42. Gillis S. T-cell-derived lymphokines. In: Paul WE, ed. Fundamental Immunology. New York: Raven Press; 1989:621-638.
43. Tamesis RR, Messmer EM, Rice BA, et al. The role of natural killer cells in the development of herpes simplex virus type 1 induced stromal keratitis in mice. Eye. 1994;8(pt3):298-306.
44. Hendricks RL, Weber PC, Taylor JL, et al. Endogenously produced interferon-α protects mice from herpes simplex type 1 corneal disease. J Gen Virol. 1991;72:1601-1610.
45. El-Asrar AM, Maimone D, Morse PH, Lascola C, Reder AT. Interferon-gamma and tumour necrosis factor induce expression of major histocompatibility complex antigen on rat retinal astrocytes. Br J Ophthalmol. 1991;75:473-475.
46. Brandt CR, Salkowski CA. Activation of NK cells in mice following corneal infection with herpes simplex virus type 1. Invest Ophthalmol Vis Sci. 1992;33:113-120.
47. Lotan M, Schwartz M. Cross talk between the immune system and the nervous system in response to injury: Implications for regeneration. FASEB J. 1994;8:1026-1033.
48. Benveniste EN. Inflammatory cytokines within the central nervous system: Sources, function, and mechanism of action. Am J Physiol. 1992;263:C1-C16.
49. Merrill JE, Jonakait GM. Interactions of the nervous and immune systems in development, normal brain homeostasis, and disease. FASEB J. 1995;9:611-618.
50. Benveniste EN, Benos DJ. TNF-α- and IFN-γ-mediated signal transduction pathways: Effects on glial cell gene expression and function. FASEB J. 1995;9:1577-1584.
51. Chakrabarti S, Sima AA, Lee J, et al. Nerve growth factor (NGF), proNGF and NGF receptor-like immunoreactivity in BB rat retina. Bruin Res. 1990;523:11-15.
52. Selmaj K, Raine CS, Cannella B, Brosnan CF. Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions. J Clin Invest. 1991;87:949-954.
53. Hattori A, Tanaka E, Murase K, et al. Tumor necrosis factor stimulates the synthesis and secretion of biologically active nerve growth factor in non-neuronal cells. J Biol Chem. 1993;268:2577-2582.
54. Wen R, Song Y, Cheng T, et al. Injury-induced upregulation of bFGF and CNTF mRNAs in the rat retina. J Neurosci. 1995;15:7377-7385.
55. Portera-Cailliau C, Sung C-H, Nathans J, Adler R. Apoptotic photoreceptor cell death in mouse models of retinitis pigmentosa. Proc Natl Acad Sci USA. 1994;91:974-978.
56. Lolley RN, Rong H, Craft CM. Linkage of photoreceptor degeneration by apoptosis with inherited defect in phototransduction. Invest Ophthalmol Vis Sci. 1994; 35:358-362.
57. Yoshida M, Yoshimura N, Hangai M, et al. Interleukin-1α, interleukin-1β, and tumor necrosis factor gene expression in endotoxin-induced uveitis. Invest Ophthalmol Vis Sci. 1994;35:1107-1113.
58. Rossol-Voth R, Rossol S, Schutt KH, et al. In vivo protective effect of tumor necrosis factor-α against experimental infection with herpes simplex virus type I. J Gen Virol. 1991;72:143-147.
59. Wietzerbin J, Gaudelet C, Catinot L, et al. Synergistic effect of interferon-gamma and tumor necrosis factor-alpha on antiviral activity and (2′-5′) oligo (A) synthetase induction in myelomonocytic cell line. J Leukoc Biol. 1990;48:149-155.
60. Chen S, Oakes JE, Lausch RN. Synergistic anti-HSV effect of tumor necrosis factor-α and interferon gamma in human corneal fibroblasts is associated with interferon-β induction. Antiviral Res. 1993;22:15-29.
61. Schijns VECJ, Van der Neut R, Haagmans BL, et al. Tumor necrosis factor-α, interferon-gamma and interferon-β exert antiviral activity in nervous tissue cells. J Gen Virol. 1991;72:809-815.
62. Schneider-Schaulies J, Schneider-Schaulies S, ter Meulen V. Differential induction of cytokines by primary and persistent measles virus infections in human glial cells. Virology. 1993;195:219-228.
63. Frei K, Malipiero UV, Leist TP, et al. On the cellular source and function of interleukin-6 in the central nervous system in viral disease. Eur J Immunol. 1989; 19:689-694.
64. Maimone D, Cioni C, Rosa S, et al. Norepinephrine and vasoactive intestinal peptide induce IL-6 secretion by astrocytes: Synergy with IL-1β and TNF-α. J Neuroimmunol. 1993;47:73-82.
65. Drescher KM. Glial cells of Müller as intraretinal immunomodulators. Baltimore: Johns Hopkins University; 1995. Thesis.