The tissue-specific transcriptional regulation of the megakaryocytic glycoprotein IIb gene is controlled by interactions between a repressor and positive cis-acting elements

Blood

Volumn 88, Issue 6, 1996, Pages 2062-2070

  Prandini, Marie Hélène ^a   Martin, Florence ^a   Thevenon, Dominique ^a   Uzan, Georges ^a  

^a CEA GRENOBLE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN IIB; TRANSCRIPTION FACTOR GATA 1;

ANIMAL CELL; ARTICLE; CELL SPECIFICITY; CELL STRAIN K 562; CONTROLLED STUDY; GENE EXPRESSION REGULATION; HELA CELL; HUMAN; HUMAN CELL; MEGAKARYOCYTE; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROMOTER REGION; REPRESSOR GENE; TISSUE SPECIFICITY; TRANSCRIPTION REGULATION;

EID: 0029818864     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v88.6.2062.bloodjournal8862062     Document Type: Article

References (41)

1. McLeod DL, Shreeve MM, Axelrad AA: Chromosome marker evidence for the bipotentiality of BFU-E. Blood 56:318, 1980
2. McDonald TP, Sullivan PS: Megakaryocytes and erythrocytic cell lines share a common precursor cell. Exp Hematol 21:1316, 1993
3. Hunt P: A bipotential megakaryocyte/erythrocyte progenitor cell: The link between erythropoiesis and megakaryocytopoiesis becomes stronger. J Lab Clin Med 125:303, 1995
4. Pevny L, Simon MC, Robertson E, Klein WH, Tsai SF, D'Agati V, Orkin SH, Constantini F: Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcriptional factor GATA-1. Nature 349:257, 1991
5. Romeo PH, Prandini MH, Joulin V, Prenant M, Vainchenker W, Marguerie G, Uzan G: Megakaryocytic and erythrocytic lineages share specific transcription factors. Nature 344:447, 1990
6. Martin DIK, Zon LI, Mutter G, Orkin SH: Expression of an erythroid transcription factor in megakaryocytic and mast cell lineages. Nature 344:444, 1990
7. Mouthon M-A, Bernard O, Mitjavila M-T, Romeo P-H, Vainchenker W, Mathieu-Mahul D: Expression of tal-1 and GATA-binding proteins during human hematopoiesis. Blood 81:647, 1993
8. Shivdasani RA, Mayer E, Orkin SH: Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL. Nature 373:432, 1995
9. Andrews NC, Erdjument-Bromage H, Davidson MB, Tempst P, Orkin SH: Erythroid transcription factor NFE2 is an haematopoietic-specific basic-leucin zipper protein. Nature 363:722, 1993
10. Molla A, Andrieux A, Chapel A Schweitzer A, Berthier R, Marguerie G: Lack of transcription and expression of the αIIb integrin in human early haematopoietic stem cells. Br J Hematol 82:635, 1992
11. Prandini MH, Denarier E, Frachet P, Uzan G, Marguerie G: Isolation of the human platelet GPIIb gene and characterisation of the 5′ flanking region. Biochem Biophys Res Commun 156:595, 1988
12. Uzan G, Prenant M, Prandini MH, Martin F, Marguerie G: Tissue-specific expression of platelet GPIIb gene. J Biol Chem 266:8932, 1991
13. Prandini M-H, Uzan G, Martin F, Thevenon D, Marguerie G: Characterization of a specific erythromegakaryocytic enhancer within the glycoprotein IIb promoter. J Biol Chem 267:10370, 1992
14. Martin F, Prandini M-H, Thevenon D, Marguerie G, Uzan G: The transcription factor GATA-1 regulates the promoter activity of the platelet glycoprotein GPIIb gene. J Biol Chem 268:21606, 1993
15. Heidenreich R, Eisman R, Surrey S, Delgrosso K, Bennett JS, Schwartz E, Poncz M: Organisation of the gene for platelet glycoprotein IIb. Biochemistry 29:1232, 1990
16. Block KL, Ravid K, Phung QH, Poncz M: Characterization of regulatory elements in the 5′-flanking region of the rat GPIIb gene by studies in a primary rat marrow culture system. Blood 84:3385, 1994
17. Lemarchandel V, Ghysdael J, Mignotte V, Rahuel C, Romeo P-H: GATA and Ets cis-acting sequences mediate megakaryocyte-specific expression. Mol Cell Biol 13:668, 1993
18. Hashimoto Y, Ware J: Identification of essential GATA and Ets binding motifs within the promoter of the platelet glycoprotein Ib gene. J Biol Chem 270:24532, 1995
19. Ravid K, Doi T, Beeler DL, Kuter DJ, Rosenberg RD: Transcriptional regulation of the rat platelet factor 4 gene: Interaction between an enhancer/silencer domain and the GATA site. Mol Cell Biol 11:6116, 1991
20. Hickey MJ, Roth GJ: Characterization of the gene encoding human platelet glycoprotein IX. J Biol Chem 268:3438, 1993
21. Lanza F, Morales M, de la Salle C, Cazenave J-P, Clemetson KJ, Shimomura T, Phillips DR: Cloning and characterization of the gene encoding the human platelet glycoprotein V. J Biol Chem 268:20801, 1993
22. Fong AM, Santoro SA: Transcriptional regulation of IIb integrin gene expression during megakaryocytic differentiation of K562 cells. J Biol Chem 269:18441, 1994
23. Luckow B, Schütz G: CAT constructions with unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements. Nucleic Acids Res 15:1311, 1987
24. Mikaelian I, Sergeant A: A general and fast method to generate multiple site directed mutagenesis. Nucleic Acids Res 20:376, 1992
25. De Wet JR, Wood KV, De Luca M, Helinski DR, Subramini S: Firefly luciferase gene: Structure and expression in mammalian cells. Mol Cell Biol 7:725, 1987
26. Gorman CM, Moffat LF, Howard BH: Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol Cell Biol 2:1044, 1982
27. Pevny L, Lin C-S, D'Agati V, Simon MC, Orkin SH, Costantini F: Development of hematopoietic cells lacking transcription factor GATA-1. Development 121:163, 1995
28. Wall L, deBoer E, Grosveld F: The human beta-globin gene 3′ enhancer contains multiple binding sites for an erythroid specific protein. Genes Dev 2:1089, 1988
29. Grosveld F, van Assendelft GB, Greaves DR, Kollias G: Position-independent, high level expression of the human β-globin gene in transgenic mice. Cell 51:975, 1987
30. Talbot D, Grosveld F: The 5′ HS 2 of the globin locus control region enhances transcription through the interaction of a multimeric complex binding at two functionally active distinct NF-E2 binding sites. EMBO J 10:1391, 1991
31. Talbot D, Philipsen S, Farser P, Grosveld F: Detailed analysis of the site 3 region of the human β globin dominant control region. EMBO J 9:2169, 1990
32. Shivdasani RA, Rosenblatt MF, Zucker-Franklin D, Jackson CW, Hunt P, Saris CJM, Orkin SH: Transcription factor NE-F2 is required for platelet formation independent of the action of thrombopoietin/MGDF in megakaryocyte development. Cell 81:695, 1995
33. Okumara N, Tsuji K, Nakahata T: Changes in the cell surface antigen expression during proliferation and differentiation of human erythroid progenitors. Blood 80:642, 1992
34. Tronik-Le Roux D, Roullot V, Schweitzer A, Berthier R, Marguerie G: Suppression of erythro-megakaryocytopoiesis and induction of reversible thrombocytopenia in mice transgenic for the thymidine kinase gene targeted by the platelet alpha IIb promoter. J Exp Med 181:2141, 1995
35. Berry M, Grosveld F, Dillon N: A single point mutation is the cause of the Greek form of hereditary persistence of fetal haemoglobin. Nature 358:499, 1992
36. Raich N, Clegg CH, Grofti J, Romeo PH, Stamatoyannopoulos G: GATA1 and YY1 are developmental repressors of the human ∈-globin gene. EMBO J 14:801, 1995
37. Kulessa H, Frampton J, Graf T: GATA-1 reprograms avian myelomonocytic cell lines into eosinophils, thromboblasts, and erythroblasts. Genes Dev 9:1250, 1995
38. Zutter MM, Painter AA, Staatz WD, Tsung YL: Regulation of α2 integrin gene expression in cells with megakaryocytic features: A common theme of three necessary elements. Blood 86:3006, 1995
39. Ramachandran B, Surrey S, Schwartz E: Megakaryocyte-specific positive regulatory sequence 5′ to the human PF4 gene. Exp Hematol 23:49, 1995
40. Denarier E, Martin F, Martineau S, Marguerie G: PCR cloning and sequence of the murine GPIIb gene promoter. Biochem Biophys Res Commun 195:1360, 1993
41. Dessen P, Fondrat C, Valencien C, Mugnier C: BISANCE: A French service for access to biomolecular sequence databases. CABIOS 6:355, 1990