Pulmonary Pathology in Surfactant-Treated Preterm Infants with Respiratory Distress Syndrome: An Autopsy Study

Neonatology

Volumn 70, Issue 1, 1996, Pages 21-28

  Toti, Paolo ^a   Buonocore, Giuseppe ^a   Rinaldi, Giuseppe ^b   Catella, Anna M ^a   Bracci, Rodolfo ^a  

^a UNIVERSITY OF SIENA   (Italy)

^b Regional Hospital   (Italy)

Author keywords

Haemorrhage; Prematurity; Pulmonary pathology; Respiratory distress syndrome; Surfactant treatment

Indexed keywords

LUNG SURFACTANT; LUNG SURFACTANT EXTRACT; OXYGEN RADICAL;

ARTICLE; AUTOPSY; CELL HYPERPLASIA; CLINICAL ARTICLE; CONTROLLED STUDY; DYSPLASIA; FEMALE; HISTOPATHOLOGY; HUMAN; HYALINE MEMBRANE DISEASE; INHALATIONAL DRUG ADMINISTRATION; LUNG ALVEOLUS CELL TYPE 2; LUNG DYSPLASIA; LUNG HEMORRHAGE; LUNG INJURY; MALE; NEWBORN; PREMATURITY; PRIORITY JOURNAL; RESPIRATORY DISTRESS SYNDROME; RETROSPECTIVE STUDY;

BRONCHOPULMONARY DYSPLASIA; FATAL OUTCOME; FEMALE; GESTATIONAL AGE; HEMORRHAGE; HUMANS; HYALINE MEMBRANE DISEASE; INFANT, NEWBORN; INFANT, PREMATURE; LUNG; LUNG DISEASES; MALE; PULMONARY ALVEOLI; PULMONARY SURFACTANTS; RESPIRATORY DISTRESS SYNDROME, NEWBORN;

EID: 0029818699     PISSN: 16617800     EISSN: 16617819     Source Type: Journal    
DOI: 10.1159/000244343     Document Type: Article

References (34)

1. Fawcett W, Gluck L: Respiratory distress syndrome in the tiny baby, Clin Perinatol 1987;4:441-451.
2. Holm BA: Surfactant replacement therapy: New levels of understanding, Am Rev Respir Dis 1993:148: 834-836.
3. Abbasi S, Bhutani VK, Gerdes JS: Long-term pulmonary consequences of respiratory distress syndrome in preterm infants treated with exogenous surfactant, J Pediatr 1993; 122: 446-452.
4. Hoekstra RE, Jackson JC, Myers TF, Frantz ID III, Stern ME, Powers WF, Maurer M, Rayc JR, Carrier ST, Gunkel JH, Gold AJ: Improved neonatal survival following multiple doses of bovine surfactant in very premature neonates at risk for respiratory distress syndrome, Pediatrics 1991:88:10-18.
5. Liechty EA, Donovan E, Purohit D, Gilhooly J, Feldman B, Noguchi A, Denson SE, Sehgal SS, Gross I, Stevens D, Ikcgami M, Zachman RD, Carrier ST, Gunkel JH, Gold AJ: Reduction of neonatal mortality after multiple doses of bovine surfactant in low birth weight neonates with respiratory distress syndrome, Pediatrics 1991;88:19-28.
6. Speer CP, Robertson B, Curstedt T, Halliday HL, Compagnonc D, Ge-feller O, Harms K, Hcrting E, McClure G, Reid M, Tubman R, Herin P, Noack G, Kok J, Koppe J, van Sonderen L, Laufkotter E, Kohler W, Boenisch H, Albrecht K, Hanssler L, Haim M, Octomo SB, Okken A, Altfeld PC, Groncck P, Kachel W, Relier JP, Walti H: Randomized European multicenter trial of surfactant replacement therapy for severe neonatal respiratory' distress syndrome: Single versus multiple doses of Curosurf, Pediatrics 1992:89:13-20.
7. Collaborative European Multicenter Study Group: Surfactant replacement therapy for severe neonatal respiratory' distress syndrome: An international randomized clinical trial, Pediatrics 1988:82:683-691.
8. Rosan RC: Hyaline membrar, e disease and a related spectrum of neonatal pneumopathies: The relationship of normal to diseased neonatal lung, Perspect Pediatr Pathol 1975; 2:15-60.
9. Anderson V, Singer DB: Iatrogenic lesions of fetuses and neonates, Neonatal intensive care: An overview (abstract), XIXth Int Congr of IAP, Madrid 1992.
10. Pinar H, Makarova N, Ruben LP, Singer DB: Pathology of the lung in surfactant-treated neonates, Pediatr Pathol 1994:14:627-636.
11. Gunther M, Vicrbuchen M, Roth B: Responder und Nonresponder in der Surfactanttherapie schr kleiner Fruhgeborener: Eine klinische, hi-stopathologischc und immunohi-stochemische Analyse, Klin Wo-chenschr 1991; 11(suppl XXVI): 224-228.
12. Thornton CM, Halliday HL, O’Hara MD: Surfactant replacement therapy in preterm neonates: A comparison of postmortem pulmonary' histology in treated and untreated infants, Pediatr Pathol 1994; 14:945-953.
13. Long W, Corbet A, Allen A, McMillan D, Boros S, Vaughan R, Gcr-des J, Houle L, Edwards K, Schiff D: Retrospective search for bleeding diathesis among premature newborn infants with pulmonary hemorrhage after synthetic surfactant treatment, J Pediatr 1992:120 (suppl):45-48.
14. Stevenson D, Walther F, Long W, Sell M, Pauly T, Gong A, Easa D, Pramanik A, LeBlanc M, Anday E, Dhanireddy R, Burchfield D, Corbet A, American Exosurf Neonatal Study Group I: Controlled trial of a single dose of synthetic surfactant at birth in premature infants weighing 500 to 699 grains, J Pediatr 1992; 120(suppl):3-12.
15. Premarick AK, Holtzman RB, Merritt TA: Surfactant replacement therapy for pulmonary diseases, Update Neonatol 1993;40:913-936.
16. Raju TNK, Langcnberger P: Pulmonary' hemorrhage and exogcncous surfactant therapy: A mctaanalysis, J Pediatr 1993;123:603-610.
17. Van Houten J, American Exosurf Neonatal Study Group, Canadian Exosurf Neonatal Study Group: Pulmonary haemorrhage in premature infants after treatment with synthetic surfactant: An autopsy evaluation, J Pediatr 1992; 120(suppl):40-44.
18. Pappin AL, Shenker N, Kack M, Rcdlinc R: Extensive intraalveolar pulmonary hemorrhage in infants dying after surfactant therapy, J Pediatr 1994;124:621-626.
19. Buonocorc G, Toti P, Zani S, Catcl-la AM, Bracci R: Lung pathology in surfactant treated preterm infants with respiratory distress syndrome (abstract), Pediatr Res 1995;38:426.
20. Bhutani VK, Abbasi S, Long WA, Gerdes JS: Pulmonary mechanics and energetics in preterm infants who had respiratory distress syndrome treated with synthetic surfactant, J Pediatr 1992; 120(suppl): 18-24.
21. Saugstad OD, Hallman M, Becher G, Oddoy A, Lachmann B: Respiratory failure caused by intratracheal saline: Additive effect of xanthine oxidase, Biol Neonate 1988;54:61-67.
22. Johnson KJ, Fanton JC, Kaplan J, Ward PA: In vivo damage of rat lungs by oxygen metabolites, J Clin Invest 1981;67:983-993.
23. Saugstad OD: Care, concern and cure in perinatal medicine; in Koppe JG, Eskes TKAB, van Geijn HP, Wiesenhaan PF, Ruys JH (eds), Oxygen Radicals in the Neonatal Period, Carnforth, Parthenon Publishing Group, 1992. pp 351-362.
24. Buonocorc G: Free oxygen radicals in neonatal lung injury; in Cosmi EV, Di Renzo G (eds): Current Progress in Perinatal Medicine, Carnforth, Parthenon Publishing Group, 1994. pp 709-722.
25. Moison RMW, OSIRIS Collaborative Group: Induction of lipid peroxidation of pulmonary' surfactant by plasma of preterm babies, Lancet 1993;341:79-82.
26. Ratych RE, Chuknyiska RS, Nbulk-ley JB: The primary’ localization of free radical generation following anoxia/reoxygcnation in isolated endothelial cells, Surgery 1987:102: 122-131.
27. Rodell TC, Cheronis JC, Ohttemus CL, Piermattci DJ, Repine JE: Xanthine oxidase mediates elastase-in-duccd injury to isolated lungs and endothelium, J Appl Physiol 1987; 63:2159-2163.
28. Rhodes PG, Hall RT, Leonidas JC: Chronic pulmonary disease in neonates with assisted ventilation, Pediatries 1975;55:788-796.
29. Nash G, Blcnnerhassett JB, Pontop-pidan H: Pulmonary lesions associated with oxygen therapy and artificial ventilation, N Engl J Med 1967; 276:368-374.
30. Northway WH Jr., Rosan RC, Sha-hinian L Jr., Catcllino RA, Gvepes MT, Durbridge T: Radiologic and histologic investigation of pulmonary oxygen toxicity in newborn guinea pigs, Invest Radiol 1969;4: 148-155.
31. Buonocorc G, Zani S, Sargentini I, Bracci R: Intraerythrocyte free iron levels and oxidative stress in the newborn (abstract), Pediatr Res 1995;37:280.
32. Buonocorc G, Zani S, Sargcntini I, Gioia D, Bracci R: The erythrocyte oxidative stress during the early neonatal period (abstract), Pediatr Res 1996:39:286.
33. Buonocorc G, Gioia D, DcFilippo M, Picciolini E, Bracci R: Superoxide anion release by polymorphonuclear leukocytes in whole blood of newborns and mothers during the peripartal period, Pediatr Res 1994; 36:619-622.
34. Martini WJ II, Rachel DL: Oxygen-mediated impairment of human pulmonary endothelial cell growth: Evidence for a specific threshold of toxicity, J Lab Clin Med 1989; 113: 413-421.